---
source: src/gnomad_pbs/gnomad2.rs
expression: records
---
- chrom: chr1
  pos: 138653
  ref_allele: C
  alt_allele: G
  filters: []
  vep:
    - allele: G
      consequence: synonymous_variant
      impact: LOW
      symbol: AL627309.1
      gene: ENSG00000237683
      feature_type: Transcript
      feature: ENST00000423372
      feature_biotype: protein_coding
      exon: 1/2
      intron: ~
      hgvsc: "ENST00000423372.3:c.657G>C"
      hgvsp: "ENST00000423372.3:c.657G>C(p.=)"
      cdna_position: "727"
      cds_position: "657"
      protein_position: "219"
      amino_acids: G
      codons: ggG/ggC
      existing_variation: ~
      dbsnp_id: "1"
      distance: ~
      strand: "-1"
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: Clone_based_ensembl_gene
      hgnc_id: ~
      canonical: true
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ENSP00000473460
      swissprot: ~
      trembl: R4GN28&B7Z7W4
      uniparc: UPI0002C88512
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
    - allele: G
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: CICP27
      gene: ENSG00000233750
      feature_type: Transcript
      feature: ENST00000442987
      feature_biotype: processed_pseudogene
      exon: ~
      intron: ~
      hgvsc: ~
      hgvsp: ~
      cdna_position: ~
      cds_position: ~
      protein_position: ~
      amino_acids: ~
      codons: ~
      existing_variation: ~
      dbsnp_id: "1"
      distance: "3817"
      strand: "1"
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: HGNC
      hgnc_id: "48835"
      canonical: true
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ~
      swissprot: ~
      trembl: ~
      uniparc: ~
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
    - allele: G
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: RP11-34P13.13
      gene: ENSG00000241860
      feature_type: Transcript
      feature: ENST00000484859
      feature_biotype: antisense
      exon: ~
      intron: ~
      hgvsc: ~
      hgvsp: ~
      cdna_position: ~
      cds_position: ~
      protein_position: ~
      amino_acids: ~
      codons: ~
      existing_variation: ~
      dbsnp_id: "1"
      distance: "2821"
      strand: "-1"
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: Clone_based_vega_gene
      hgnc_id: ~
      canonical: true
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ~
      swissprot: ~
      trembl: ~
      uniparc: ~
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
    - allele: G
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: RP11-34P13.13
      gene: ENSG00000241860
      feature_type: Transcript
      feature: ENST00000490997
      feature_biotype: antisense
      exon: ~
      intron: ~
      hgvsc: ~
      hgvsp: ~
      cdna_position: ~
      cds_position: ~
      protein_position: ~
      amino_acids: ~
      codons: ~
      existing_variation: ~
      dbsnp_id: "1"
      distance: "4155"
      strand: "-1"
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: Clone_based_vega_gene
      hgnc_id: ~
      canonical: false
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ~
      swissprot: ~
      trembl: ~
      uniparc: ~
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
    - allele: G
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: RP11-34P13.14
      gene: ENSG00000239906
      feature_type: Transcript
      feature: ENST00000493797
      feature_biotype: antisense
      exon: ~
      intron: ~
      hgvsc: ~
      hgvsp: ~
      cdna_position: ~
      cds_position: ~
      protein_position: ~
      amino_acids: ~
      codons: ~
      existing_variation: ~
      dbsnp_id: "1"
      distance: "1137"
      strand: "-1"
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: Clone_based_vega_gene
      hgnc_id: ~
      canonical: true
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ~
      swissprot: ~
      trembl: ~
      uniparc: ~
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
    - allele: G
      consequence: upstream_gene_variant
      impact: MODIFIER
      symbol: RP11-34P13.15
      gene: ENSG00000268903
      feature_type: Transcript
      feature: ENST00000494149
      feature_biotype: processed_pseudogene
      exon: ~
      intron: ~
      hgvsc: ~
      hgvsp: ~
      cdna_position: ~
      cds_position: ~
      protein_position: ~
      amino_acids: ~
      codons: ~
      existing_variation: ~
      dbsnp_id: "1"
      distance: "2758"
      strand: "-1"
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: Clone_based_vega_gene
      hgnc_id: ~
      canonical: true
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ~
      swissprot: ~
      trembl: ~
      uniparc: ~
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
    - allele: G
      consequence: upstream_gene_variant
      impact: MODIFIER
      symbol: RP11-34P13.16
      gene: ENSG00000269981
      feature_type: Transcript
      feature: ENST00000595919
      feature_biotype: processed_pseudogene
      exon: ~
      intron: ~
      hgvsc: ~
      hgvsp: ~
      cdna_position: ~
      cds_position: ~
      protein_position: ~
      amino_acids: ~
      codons: ~
      existing_variation: ~
      dbsnp_id: "1"
      distance: "688"
      strand: "-1"
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: Clone_based_vega_gene
      hgnc_id: ~
      canonical: true
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ~
      swissprot: ~
      trembl: ~
      uniparc: ~
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
    - allele: G
      consequence: regulatory_region_variant
      impact: MODIFIER
      symbol: ""
      gene: ""
      feature_type: RegulatoryFeature
      feature: ENSR00000668505
      feature_biotype: CTCF_binding_site
      exon: ~
      intron: ~
      hgvsc: ~
      hgvsp: ~
      cdna_position: ~
      cds_position: ~
      protein_position: ~
      amino_acids: ~
      codons: ~
      existing_variation: ~
      dbsnp_id: "1"
      distance: ~
      strand: ~
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: ~
      hgnc_id: ~
      canonical: false
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ~
      swissprot: ~
      trembl: ~
      uniparc: ~
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
  allele_counts:
    - cohort: ~
      by_population:
        - population: afr
          counts:
            overall:
              ac: 0
              an: 5224
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 2998
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 2226
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: amr
          counts:
            overall:
              ac: 0
              an: 10882
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 5942
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 4940
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              ac: 0
              an: 1506
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 842
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 664
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: eas
          counts:
            overall:
              ac: 0
              an: 7858
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 3798
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 4060
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: eas_jpn
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_oea
          counts:
            overall:
              ac: 0
              an: 5990
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_kor
          counts:
            overall:
              ac: 0
              an: 1868
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: fin
          counts:
            overall:
              ac: 0
              an: 732
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 350
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 382
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: nfe
          counts:
            overall:
              ac: 0
              an: 20660
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 10040
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 10620
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: nfe_bgr
          counts:
            overall:
              ac: 0
              an: 4
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_est
          counts:
            overall:
              ac: 0
              an: 58
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_nwe
          counts:
            overall:
              ac: 0
              an: 16524
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_onf
          counts:
            overall:
              ac: 0
              an: 4024
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_seu
          counts:
            overall:
              ac: 0
              an: 46
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_swe
          counts:
            overall:
              ac: 0
              an: 4
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: oth
          counts:
            overall:
              ac: 0
              an: 1922
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 932
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 990
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: sas
          counts:
            overall:
              ac: 4
              an: 6086
              nhomalt: 0
              af: 0.000657246
            xx:
              ac: 0
              an: 2388
              nhomalt: 0
              af: 0
            xy:
              ac: 4
              an: 3698
              nhomalt: 0
              af: 0.00108167
          faf95: 0.00022377
          faf99: 0.00022383
      by_sex:
        overall:
          ac: 4
          an: 54870
          nhomalt: 0
          af: 0.0000728996
        xx:
          ac: 0
          an: 27290
          nhomalt: 0
          af: 0
        xy:
          ac: 4
          an: 27580
          nhomalt: 0
          af: 0.000145033
      raw:
        ac: 4
        an: 105176
        nhomalt: 0
        af: 0.0000380315
      popmax: sas
      af_popmax: 0.000657246
      ac_popmax: 4
      an_popmax: 6086
      nhomalt_popmax: 0
    - cohort: controls
      by_population:
        - population: afr
          counts:
            overall:
              ac: 0
              an: 2242
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 1298
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 944
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: amr
          counts:
            overall:
              ac: 0
              an: 5530
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 3116
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 2414
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              ac: 0
              an: 276
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 124
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 152
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: eas
          counts:
            overall:
              ac: 0
              an: 3874
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 1948
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 1926
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: eas_jpn
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_oea
          counts:
            overall:
              ac: 0
              an: 2946
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_kor
          counts:
            overall:
              ac: 0
              an: 928
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: fin
          counts:
            overall:
              ac: 0
              an: 26
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 14
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 12
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: nfe
          counts:
            overall:
              ac: 0
              an: 7114
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 3750
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 3364
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: nfe_bgr
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_est
          counts:
            overall:
              ac: 0
              an: 20
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_nwe
          counts:
            overall:
              ac: 0
              an: 5864
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_onf
          counts:
            overall:
              ac: 0
              an: 1230
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_seu
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_swe
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: oth
          counts:
            overall:
              ac: 0
              an: 702
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 360
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 342
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: sas
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            overall:
              ac: 1
              an: 2804
              nhomalt: 0
              af: 0.000356633
            xx:
              ac: 0
              an: 1108
              nhomalt: 0
              af: 0
            xy:
              ac: 1
              an: 1696
              nhomalt: 0
              af: 0.000589623
          faf95: 0.00022377
          faf99: 0.00022383
      by_sex:
        overall:
          ac: 1
          an: 22568
          nhomalt: 0
          af: 0.0000443105
        xx:
          ac: 0
          an: 11718
          nhomalt: 0
          af: 0
        xy:
          ac: 1
          an: 10850
          nhomalt: 0
          af: 0.0000921659
      raw:
        ac: 1
        an: 42382
        nhomalt: 0
        af: 0.0000235949
      popmax: sas
      af_popmax: 0.000356633
      ac_popmax: 1
      an_popmax: 2804
      nhomalt_popmax: 0
    - cohort: non_cancer
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        - population: afr
          counts:
            overall:
              ac: 0
              an: 5224
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 2998
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 2226
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: amr
          counts:
            overall:
              ac: 0
              an: 10882
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 5942
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 4940
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: asj
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            overall:
              ac: 0
              an: 1506
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 842
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 664
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: eas
          counts:
            overall:
              ac: 0
              an: 7858
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 3798
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 4060
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: eas_jpn
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_oea
          counts:
            overall:
              ac: 0
              an: 5990
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_kor
          counts:
            overall:
              ac: 0
              an: 1868
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: fin
          counts:
            overall:
              ac: 0
              an: 732
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 350
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 382
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: nfe
          counts:
            overall:
              ac: 0
              an: 20660
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 10040
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 10620
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: nfe_bgr
          counts:
            overall:
              ac: 0
              an: 4
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_est
          counts:
            overall:
              ac: 0
              an: 58
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_nwe
          counts:
            overall:
              ac: 0
              an: 16524
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_onf
          counts:
            overall:
              ac: 0
              an: 4024
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_seu
          counts:
            overall:
              ac: 0
              an: 46
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_swe
          counts:
            overall:
              ac: 0
              an: 4
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: oth
          counts:
            overall:
              ac: 0
              an: 1922
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 932
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 990
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: sas
          counts:
            overall:
              ac: 4
              an: 6086
              nhomalt: 0
              af: 0.000657246
            xx:
              ac: 0
              an: 2388
              nhomalt: 0
              af: 0
            xy:
              ac: 4
              an: 3698
              nhomalt: 0
              af: 0.00108167
          faf95: 0.00022377
          faf99: 0.00022383
      by_sex:
        overall:
          ac: 4
          an: 54870
          nhomalt: 0
          af: 0.0000728996
        xx:
          ac: 0
          an: 27290
          nhomalt: 0
          af: 0
        xy:
          ac: 4
          an: 27580
          nhomalt: 0
          af: 0.000145033
      raw:
        ac: 4
        an: 104932
        nhomalt: 0
        af: 0.0000381199
      popmax: sas
      af_popmax: 0.000657246
      ac_popmax: 4
      an_popmax: 6086
      nhomalt_popmax: 0
    - cohort: non_neuro
      by_population:
        - population: afr
          counts:
            overall:
              ac: 0
              an: 5192
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 2984
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 2208
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: amr
          counts:
            overall:
              ac: 0
              an: 7626
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 4234
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 3392
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              ac: 0
              an: 654
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 294
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 360
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: eas
          counts:
            overall:
              ac: 0
              an: 7846
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 3790
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 4056
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: eas_jpn
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_oea
          counts:
            overall:
              ac: 0
              an: 5980
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_kor
          counts:
            overall:
              ac: 0
              an: 1866
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: fin
          counts:
            overall:
              ac: 0
              an: 500
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 186
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 314
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: nfe
          counts:
            overall:
              ac: 0
              an: 16902
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 8748
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 8154
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: nfe_bgr
          counts:
            overall:
              ac: 0
              an: 4
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_est
          counts:
            overall:
              ac: 0
              an: 50
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_nwe
          counts:
            overall:
              ac: 0
              an: 13448
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_onf
          counts:
            overall:
              ac: 0
              an: 3394
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_seu
          counts:
            overall:
              ac: 0
              an: 2
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_swe
          counts:
            overall:
              ac: 0
              an: 4
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: oth
          counts:
            overall:
              ac: 0
              an: 1536
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 790
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 746
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: sas
          counts:
            overall:
              ac: 4
              an: 6084
              nhomalt: 0
              af: 0.000657462
            xx:
              ac: 0
              an: 2388
              nhomalt: 0
              af: 0
            xy:
              ac: 4
              an: 3696
              nhomalt: 0
              af: 0.00108225
          faf95: 0.00022377
          faf99: 0.00022383
      by_sex:
        overall:
          ac: 4
          an: 46340
          nhomalt: 0
          af: 0.0000863185
        xx:
          ac: 0
          an: 23414
          nhomalt: 0
          af: 0
        xy:
          ac: 4
          an: 22926
          nhomalt: 0
          af: 0.000174474
      raw:
        ac: 4
        an: 89150
        nhomalt: 0
        af: 0.0000448682
      popmax: sas
      af_popmax: 0.000657462
      ac_popmax: 4
      an_popmax: 6084
      nhomalt_popmax: 0
    - cohort: non_topmed
      by_population:
        - population: afr
          counts:
            overall:
              ac: 0
              an: 5074
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 2900
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 2174
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: amr
          counts:
            overall:
              ac: 0
              an: 10844
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 5920
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 4924
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              ac: 0
              an: 1478
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 828
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 650
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: eas
          counts:
            overall:
              ac: 0
              an: 7856
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 3798
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 4058
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: eas_jpn
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_oea
          counts:
            overall:
              ac: 0
              an: 5988
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_kor
          counts:
            overall:
              ac: 0
              an: 1868
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: fin
          counts:
            overall:
              ac: 0
              an: 730
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 348
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 382
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: nfe
          counts:
            overall:
              ac: 0
              an: 19652
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 9496
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 10156
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: nfe_bgr
          counts:
            overall:
              ac: 0
              an: 4
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_est
          counts:
            overall:
              ac: 0
              an: 54
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_nwe
          counts:
            overall:
              ac: 0
              an: 15814
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_onf
          counts:
            overall:
              ac: 0
              an: 3730
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_seu
          counts:
            overall:
              ac: 0
              an: 46
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_swe
          counts:
            overall:
              ac: 0
              an: 4
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: oth
          counts:
            overall:
              ac: 0
              an: 1878
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 908
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 970
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: sas
          counts:
            overall:
              ac: 4
              an: 6086
              nhomalt: 0
              af: 0.000657246
            xx:
              ac: 0
              an: 2388
              nhomalt: 0
              af: 0
            xy:
              ac: 4
              an: 3698
              nhomalt: 0
              af: 0.00108167
          faf95: 0.00022377
          faf99: 0.00022383
      by_sex:
        overall:
          ac: 4
          an: 53598
          nhomalt: 0
          af: 0.0000746297
        xx:
          ac: 0
          an: 26586
          nhomalt: 0
          af: 0
        xy:
          ac: 4
          an: 27012
          nhomalt: 0
          af: 0.000148082
      raw:
        ac: 4
        an: 103858
        nhomalt: 0
        af: 0.0000385141
      popmax: sas
      af_popmax: 0.000657246
      ac_popmax: 4
      an_popmax: 6086
      nhomalt_popmax: 0
  nonpar: false
  liftover_info:
    reverse_complemented_alleles: false
    swapped_alleles: false
    original_alleles: []
    original_contig: "1"
    original_start: "138653"
  rf_info:
    rf_tp_probability: 0.561271
    rf_positive_label: false
    rf_negative_label: false
    rf_label: ~
    rf_train: false
  variant_info:
    variant_type: multi-snv
    allele_type: snv
    n_alt_alleles: 3
    was_mixed: false
    has_star: false
  quality_info:
    fs: 2.105
    inbreeding_coeff: 0.0985
    mq: 36.33
    mq_rank_sum: -0.376
    qd: 8.31
    read_pos_rank_sum: 0.84
    vqsr_positive_train_site: false
    vqsr_negative_train_site: false
    base_q_rank_sum: 1.04
    clipping_rank_sum: 0.374
    sor: 0.908
    dp: 4939758
    vqslod: 0.796
    vqsr_culprit: MQ
    segdup: true
    lcr: false
    decoy: false
    transmitted_singleton: false
    pab_max: 0.0423948
  age_info:
    age_hist_hom_bin_freq: []
    age_hist_hom_n_smaller: 0
    age_hist_hom_n_larger: 0
    age_hist_het_bin_freq: []
    age_hist_het_n_smaller: 0
    age_hist_het_n_larger: 0
  depth_info:
    dp_hist_all_n_larger: 15029
    dp_hist_alt_n_larger: 4
    dp_hist_all_bin_freq: []
    dp_hist_alt_bin_freq: []
- chrom: chr1
  pos: 138654
  ref_allele: C
  alt_allele: T
  filters: []
  vep:
    - allele: T
      consequence: missense_variant
      impact: MODERATE
      symbol: AL627309.1
      gene: ENSG00000237683
      feature_type: Transcript
      feature: ENST00000423372
      feature_biotype: protein_coding
      exon: 1/2
      intron: ~
      hgvsc: "ENST00000423372.3:c.656G>A"
      hgvsp: "ENSP00000473460.1:p.Gly219Glu"
      cdna_position: "726"
      cds_position: "656"
      protein_position: "219"
      amino_acids: G/E
      codons: gGg/gAg
      existing_variation: ~
      dbsnp_id: "1"
      distance: ~
      strand: "-1"
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: Clone_based_ensembl_gene
      hgnc_id: ~
      canonical: true
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ENSP00000473460
      swissprot: ~
      trembl: R4GN28&B7Z7W4
      uniparc: UPI0002C88512
      gene_pheno: ~
      sift:
        prediction: deleterious
        score: 0.03
      polyphen:
        prediction: benign
        score: 0.057
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
    - allele: T
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: CICP27
      gene: ENSG00000233750
      feature_type: Transcript
      feature: ENST00000442987
      feature_biotype: processed_pseudogene
      exon: ~
      intron: ~
      hgvsc: ~
      hgvsp: ~
      cdna_position: ~
      cds_position: ~
      protein_position: ~
      amino_acids: ~
      codons: ~
      existing_variation: ~
      dbsnp_id: "1"
      distance: "3818"
      strand: "1"
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: HGNC
      hgnc_id: "48835"
      canonical: true
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ~
      swissprot: ~
      trembl: ~
      uniparc: ~
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
    - allele: T
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: RP11-34P13.13
      gene: ENSG00000241860
      feature_type: Transcript
      feature: ENST00000484859
      feature_biotype: antisense
      exon: ~
      intron: ~
      hgvsc: ~
      hgvsp: ~
      cdna_position: ~
      cds_position: ~
      protein_position: ~
      amino_acids: ~
      codons: ~
      existing_variation: ~
      dbsnp_id: "1"
      distance: "2820"
      strand: "-1"
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: Clone_based_vega_gene
      hgnc_id: ~
      canonical: true
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ~
      swissprot: ~
      trembl: ~
      uniparc: ~
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
    - allele: T
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: RP11-34P13.13
      gene: ENSG00000241860
      feature_type: Transcript
      feature: ENST00000490997
      feature_biotype: antisense
      exon: ~
      intron: ~
      hgvsc: ~
      hgvsp: ~
      cdna_position: ~
      cds_position: ~
      protein_position: ~
      amino_acids: ~
      codons: ~
      existing_variation: ~
      dbsnp_id: "1"
      distance: "4154"
      strand: "-1"
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: Clone_based_vega_gene
      hgnc_id: ~
      canonical: false
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ~
      swissprot: ~
      trembl: ~
      uniparc: ~
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
    - allele: T
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: RP11-34P13.14
      gene: ENSG00000239906
      feature_type: Transcript
      feature: ENST00000493797
      feature_biotype: antisense
      exon: ~
      intron: ~
      hgvsc: ~
      hgvsp: ~
      cdna_position: ~
      cds_position: ~
      protein_position: ~
      amino_acids: ~
      codons: ~
      existing_variation: ~
      dbsnp_id: "1"
      distance: "1136"
      strand: "-1"
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: Clone_based_vega_gene
      hgnc_id: ~
      canonical: true
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ~
      swissprot: ~
      trembl: ~
      uniparc: ~
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
    - allele: T
      consequence: upstream_gene_variant
      impact: MODIFIER
      symbol: RP11-34P13.15
      gene: ENSG00000268903
      feature_type: Transcript
      feature: ENST00000494149
      feature_biotype: processed_pseudogene
      exon: ~
      intron: ~
      hgvsc: ~
      hgvsp: ~
      cdna_position: ~
      cds_position: ~
      protein_position: ~
      amino_acids: ~
      codons: ~
      existing_variation: ~
      dbsnp_id: "1"
      distance: "2759"
      strand: "-1"
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: Clone_based_vega_gene
      hgnc_id: ~
      canonical: true
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ~
      swissprot: ~
      trembl: ~
      uniparc: ~
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
    - allele: T
      consequence: upstream_gene_variant
      impact: MODIFIER
      symbol: RP11-34P13.16
      gene: ENSG00000269981
      feature_type: Transcript
      feature: ENST00000595919
      feature_biotype: processed_pseudogene
      exon: ~
      intron: ~
      hgvsc: ~
      hgvsp: ~
      cdna_position: ~
      cds_position: ~
      protein_position: ~
      amino_acids: ~
      codons: ~
      existing_variation: ~
      dbsnp_id: "1"
      distance: "689"
      strand: "-1"
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: Clone_based_vega_gene
      hgnc_id: ~
      canonical: true
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ~
      swissprot: ~
      trembl: ~
      uniparc: ~
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
    - allele: T
      consequence: regulatory_region_variant
      impact: MODIFIER
      symbol: ""
      gene: ""
      feature_type: RegulatoryFeature
      feature: ENSR00000668505
      feature_biotype: CTCF_binding_site
      exon: ~
      intron: ~
      hgvsc: ~
      hgvsp: ~
      cdna_position: ~
      cds_position: ~
      protein_position: ~
      amino_acids: ~
      codons: ~
      existing_variation: ~
      dbsnp_id: "1"
      distance: ~
      strand: ~
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: ~
      hgnc_id: ~
      canonical: false
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ~
      swissprot: ~
      trembl: ~
      uniparc: ~
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
  allele_counts:
    - cohort: ~
      by_population:
        - population: afr
          counts:
            overall:
              ac: 0
              an: 5224
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 2998
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 2226
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: amr
          counts:
            overall:
              ac: 2
              an: 10890
              nhomalt: 0
              af: 0.000183655
            xx:
              ac: 1
              an: 5948
              nhomalt: 0
              af: 0.000168124
            xy:
              ac: 1
              an: 4942
              nhomalt: 0
              af: 0.000202347
          faf95: 0.00003227
          faf99: 0.0000323
        - population: asj
          counts:
            overall:
              ac: 0
              an: 1508
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 844
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 664
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: eas
          counts:
            overall:
              ac: 0
              an: 7858
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 3798
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 4060
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: eas_jpn
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_oea
          counts:
            overall:
              ac: 0
              an: 5990
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_kor
          counts:
            overall:
              ac: 0
              an: 1868
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: fin
          counts:
            overall:
              ac: 0
              an: 732
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 352
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 380
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: nfe
          counts:
            overall:
              ac: 0
              an: 20686
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 10050
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 10636
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: nfe_bgr
          counts:
            overall:
              ac: 0
              an: 4
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_est
          counts:
            overall:
              ac: 0
              an: 58
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_nwe
          counts:
            overall:
              ac: 0
              an: 16544
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_onf
          counts:
            overall:
              ac: 0
              an: 4030
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_seu
          counts:
            overall:
              ac: 0
              an: 48
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_swe
          counts:
            overall:
              ac: 0
              an: 2
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: oth
          counts:
            overall:
              ac: 0
              an: 1920
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 930
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 990
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: sas
          counts:
            overall:
              ac: 0
              an: 6084
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 2390
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 3694
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
      by_sex:
        overall:
          ac: 2
          an: 54902
          nhomalt: 0
          af: 0.0000364285
        xx:
          ac: 1
          an: 27310
          nhomalt: 0
          af: 0.0000366166
        xy:
          ac: 1
          an: 27592
          nhomalt: 0
          af: 0.0000362424
      raw:
        ac: 3
        an: 105366
        nhomalt: 0
        af: 0.0000284722
      popmax: amr
      af_popmax: 0.000183655
      ac_popmax: 2
      an_popmax: 10890
      nhomalt_popmax: 0
    - cohort: controls
      by_population:
        - population: afr
          counts:
            overall:
              ac: 0
              an: 2242
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 1298
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 944
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: amr
          counts:
            overall:
              ac: 0
              an: 5538
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 3126
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 2412
              nhomalt: 0
              af: 0
          faf95: 0.00003227
          faf99: 0.0000323
        - population: asj
          counts:
            overall:
              ac: 0
              an: 276
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 124
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 152
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: eas
          counts:
            overall:
              ac: 0
              an: 3874
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 1948
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 1926
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: eas_jpn
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_oea
          counts:
            overall:
              ac: 0
              an: 2946
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_kor
          counts:
            overall:
              ac: 0
              an: 928
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: fin
          counts:
            overall:
              ac: 0
              an: 26
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 14
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 12
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: nfe
          counts:
            overall:
              ac: 0
              an: 7122
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 3754
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 3368
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: nfe_bgr
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_est
          counts:
            overall:
              ac: 0
              an: 20
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_nwe
          counts:
            overall:
              ac: 0
              an: 5868
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_onf
          counts:
            overall:
              ac: 0
              an: 1234
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_seu
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_swe
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: oth
          counts:
            overall:
              ac: 0
              an: 700
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 358
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 342
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: sas
          counts:
            overall:
              ac: 0
              an: 2804
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 1110
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 1694
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
      by_sex:
        overall:
          ac: 0
          an: 22582
          nhomalt: 0
          af: 0
        xx:
          ac: 0
          an: 11732
          nhomalt: 0
          af: 0
        xy:
          ac: 0
          an: 10850
          nhomalt: 0
          af: 0
      raw:
        ac: 0
        an: 42482
        nhomalt: 0
        af: 0
      popmax: ~
      af_popmax: ~
      ac_popmax: ~
      an_popmax: ~
      nhomalt_popmax: ~
    - cohort: non_cancer
      by_population:
        - population: afr
          counts:
            overall:
              ac: 0
              an: 5224
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 2998
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 2226
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: amr
          counts:
            overall:
              ac: 2
              an: 10890
              nhomalt: 0
              af: 0.000183655
            xx:
              ac: 1
              an: 5948
              nhomalt: 0
              af: 0.000168124
            xy:
              ac: 1
              an: 4942
              nhomalt: 0
              af: 0.000202347
          faf95: 0.00003227
          faf99: 0.0000323
        - population: asj
          counts:
            overall:
              ac: 0
              an: 1508
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 844
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 664
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: eas
          counts:
            overall:
              ac: 0
              an: 7858
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 3798
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 4060
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: eas_jpn
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_oea
          counts:
            overall:
              ac: 0
              an: 5990
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_kor
          counts:
            overall:
              ac: 0
              an: 1868
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: fin
          counts:
            overall:
              ac: 0
              an: 732
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 352
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 380
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: nfe
          counts:
            overall:
              ac: 0
              an: 20686
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 10050
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 10636
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: nfe_bgr
          counts:
            overall:
              ac: 0
              an: 4
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_est
          counts:
            overall:
              ac: 0
              an: 58
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_nwe
          counts:
            overall:
              ac: 0
              an: 16544
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_onf
          counts:
            overall:
              ac: 0
              an: 4030
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_seu
          counts:
            overall:
              ac: 0
              an: 48
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_swe
          counts:
            overall:
              ac: 0
              an: 2
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: oth
          counts:
            overall:
              ac: 0
              an: 1920
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 930
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 990
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: sas
          counts:
            overall:
              ac: 0
              an: 6084
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 2390
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 3694
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
      by_sex:
        overall:
          ac: 2
          an: 54902
          nhomalt: 0
          af: 0.0000364285
        xx:
          ac: 1
          an: 27310
          nhomalt: 0
          af: 0.0000366166
        xy:
          ac: 1
          an: 27592
          nhomalt: 0
          af: 0.0000362424
      raw:
        ac: 3
        an: 105112
        nhomalt: 0
        af: 0.000028541
      popmax: amr
      af_popmax: 0.000183655
      ac_popmax: 2
      an_popmax: 10890
      nhomalt_popmax: 0
    - cohort: non_neuro
      by_population:
        - population: afr
          counts:
            overall:
              ac: 0
              an: 5192
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 2984
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 2208
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: amr
          counts:
            overall:
              ac: 1
              an: 7636
              nhomalt: 0
              af: 0.000130959
            xx:
              ac: 1
              an: 4242
              nhomalt: 0
              af: 0.000235738
            xy:
              ac: 0
              an: 3394
              nhomalt: 0
              af: 0
          faf95: 0.00003227
          faf99: 0.0000323
        - population: asj
          counts:
            overall:
              ac: 0
              an: 656
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 296
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 360
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: eas
          counts:
            overall:
              ac: 0
              an: 7846
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 3790
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 4056
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: eas_jpn
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_oea
          counts:
            overall:
              ac: 0
              an: 5980
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_kor
          counts:
            overall:
              ac: 0
              an: 1866
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: fin
          counts:
            overall:
              ac: 0
              an: 500
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 188
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 312
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: nfe
          counts:
            overall:
              ac: 0
              an: 16918
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 8754
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 8164
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: nfe_bgr
          counts:
            overall:
              ac: 0
              an: 4
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_est
          counts:
            overall:
              ac: 0
              an: 50
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_nwe
          counts:
            overall:
              ac: 0
              an: 13466
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_onf
          counts:
            overall:
              ac: 0
              an: 3394
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_seu
          counts:
            overall:
              ac: 0
              an: 2
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_swe
          counts:
            overall:
              ac: 0
              an: 2
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: oth
          counts:
            overall:
              ac: 0
              an: 1534
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 788
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 746
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: sas
          counts:
            overall:
              ac: 0
              an: 6082
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 2390
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 3692
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
      by_sex:
        overall:
          ac: 1
          an: 46364
          nhomalt: 0
          af: 0.0000215685
        xx:
          ac: 1
          an: 23432
          nhomalt: 0
          af: 0.0000426767
        xy:
          ac: 0
          an: 22932
          nhomalt: 0
          af: 0
      raw:
        ac: 2
        an: 89314
        nhomalt: 0
        af: 0.0000223929
      popmax: amr
      af_popmax: 0.000130959
      ac_popmax: 1
      an_popmax: 7636
      nhomalt_popmax: 0
    - cohort: non_topmed
      by_population:
        - population: afr
          counts:
            overall:
              ac: 0
              an: 5074
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 2900
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 2174
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: amr
          counts:
            overall:
              ac: 2
              an: 10852
              nhomalt: 0
              af: 0.000184298
            xx:
              ac: 1
              an: 5926
              nhomalt: 0
              af: 0.000168748
            xy:
              ac: 1
              an: 4926
              nhomalt: 0
              af: 0.000203004
          faf95: 0.00003227
          faf99: 0.0000323
        - population: asj
          counts:
            overall:
              ac: 0
              an: 1480
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 830
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 650
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: eas
          counts:
            overall:
              ac: 0
              an: 7856
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 3798
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 4058
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: eas_jpn
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_oea
          counts:
            overall:
              ac: 0
              an: 5988
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_kor
          counts:
            overall:
              ac: 0
              an: 1868
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: fin
          counts:
            overall:
              ac: 0
              an: 730
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 350
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 380
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: nfe
          counts:
            overall:
              ac: 0
              an: 19678
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 9506
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 10172
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: nfe_bgr
          counts:
            overall:
              ac: 0
              an: 4
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_est
          counts:
            overall:
              ac: 0
              an: 54
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_nwe
          counts:
            overall:
              ac: 0
              an: 15834
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_onf
          counts:
            overall:
              ac: 0
              an: 3736
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_seu
          counts:
            overall:
              ac: 0
              an: 48
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_swe
          counts:
            overall:
              ac: 0
              an: 2
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: oth
          counts:
            overall:
              ac: 0
              an: 1876
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 906
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 970
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: sas
          counts:
            overall:
              ac: 0
              an: 6084
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 2390
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 3694
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
      by_sex:
        overall:
          ac: 2
          an: 53630
          nhomalt: 0
          af: 0.0000372926
        xx:
          ac: 1
          an: 26606
          nhomalt: 0
          af: 0.0000375855
        xy:
          ac: 1
          an: 27024
          nhomalt: 0
          af: 0.0000370041
      raw:
        ac: 3
        an: 104050
        nhomalt: 0
        af: 0.0000288323
      popmax: amr
      af_popmax: 0.000184298
      ac_popmax: 2
      an_popmax: 10852
      nhomalt_popmax: 0
  nonpar: false
  liftover_info:
    reverse_complemented_alleles: false
    swapped_alleles: false
    original_alleles: []
    original_contig: "1"
    original_start: "138654"
  rf_info:
    rf_tp_probability: 0.0797253
    rf_positive_label: false
    rf_negative_label: false
    rf_label: ~
    rf_train: false
  variant_info:
    variant_type: snv
    allele_type: snv
    n_alt_alleles: 1
    was_mixed: false
    has_star: false
  quality_info:
    fs: 0.508
    inbreeding_coeff: -0.0431
    mq: 36.86
    mq_rank_sum: 0.482
    qd: 5.59
    read_pos_rank_sum: 0.516
    vqsr_positive_train_site: false
    vqsr_negative_train_site: false
    base_q_rank_sum: 3.84
    clipping_rank_sum: -0.328
    sor: 0.638
    dp: 4938132
    vqslod: 0.585
    vqsr_culprit: QD
    segdup: true
    lcr: false
    decoy: false
    transmitted_singleton: false
    pab_max: 1
  age_info:
    age_hist_hom_bin_freq: []
    age_hist_hom_n_smaller: 0
    age_hist_hom_n_larger: 0
    age_hist_het_bin_freq: []
    age_hist_het_n_smaller: 0
    age_hist_het_n_larger: 0
  depth_info:
    dp_hist_all_n_larger: 15028
    dp_hist_alt_n_larger: 2
    dp_hist_all_bin_freq: []
    dp_hist_alt_bin_freq: []
- chrom: chr1
  pos: 138667
  ref_allele: G
  alt_allele: C
  filters: []
  vep:
    - allele: C
      consequence: missense_variant
      impact: MODERATE
      symbol: AL627309.1
      gene: ENSG00000237683
      feature_type: Transcript
      feature: ENST00000423372
      feature_biotype: protein_coding
      exon: 1/2
      intron: ~
      hgvsc: "ENST00000423372.3:c.643C>G"
      hgvsp: "ENSP00000473460.1:p.Leu215Val"
      cdna_position: "713"
      cds_position: "643"
      protein_position: "215"
      amino_acids: L/V
      codons: Ctt/Gtt
      existing_variation: ~
      dbsnp_id: "1"
      distance: ~
      strand: "-1"
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: Clone_based_ensembl_gene
      hgnc_id: ~
      canonical: true
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ENSP00000473460
      swissprot: ~
      trembl: R4GN28&B7Z7W4
      uniparc: UPI0002C88512
      gene_pheno: ~
      sift:
        prediction: tolerated
        score: 0.09
      polyphen:
        prediction: possibly_damaging
        score: 0.801
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
    - allele: C
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: CICP27
      gene: ENSG00000233750
      feature_type: Transcript
      feature: ENST00000442987
      feature_biotype: processed_pseudogene
      exon: ~
      intron: ~
      hgvsc: ~
      hgvsp: ~
      cdna_position: ~
      cds_position: ~
      protein_position: ~
      amino_acids: ~
      codons: ~
      existing_variation: ~
      dbsnp_id: "1"
      distance: "3831"
      strand: "1"
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: HGNC
      hgnc_id: "48835"
      canonical: true
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ~
      swissprot: ~
      trembl: ~
      uniparc: ~
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
    - allele: C
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: RP11-34P13.13
      gene: ENSG00000241860
      feature_type: Transcript
      feature: ENST00000484859
      feature_biotype: antisense
      exon: ~
      intron: ~
      hgvsc: ~
      hgvsp: ~
      cdna_position: ~
      cds_position: ~
      protein_position: ~
      amino_acids: ~
      codons: ~
      existing_variation: ~
      dbsnp_id: "1"
      distance: "2807"
      strand: "-1"
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: Clone_based_vega_gene
      hgnc_id: ~
      canonical: true
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ~
      swissprot: ~
      trembl: ~
      uniparc: ~
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
    - allele: C
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: RP11-34P13.13
      gene: ENSG00000241860
      feature_type: Transcript
      feature: ENST00000490997
      feature_biotype: antisense
      exon: ~
      intron: ~
      hgvsc: ~
      hgvsp: ~
      cdna_position: ~
      cds_position: ~
      protein_position: ~
      amino_acids: ~
      codons: ~
      existing_variation: ~
      dbsnp_id: "1"
      distance: "4141"
      strand: "-1"
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: Clone_based_vega_gene
      hgnc_id: ~
      canonical: false
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ~
      swissprot: ~
      trembl: ~
      uniparc: ~
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
    - allele: C
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: RP11-34P13.14
      gene: ENSG00000239906
      feature_type: Transcript
      feature: ENST00000493797
      feature_biotype: antisense
      exon: ~
      intron: ~
      hgvsc: ~
      hgvsp: ~
      cdna_position: ~
      cds_position: ~
      protein_position: ~
      amino_acids: ~
      codons: ~
      existing_variation: ~
      dbsnp_id: "1"
      distance: "1123"
      strand: "-1"
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: Clone_based_vega_gene
      hgnc_id: ~
      canonical: true
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ~
      swissprot: ~
      trembl: ~
      uniparc: ~
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
    - allele: C
      consequence: upstream_gene_variant
      impact: MODIFIER
      symbol: RP11-34P13.15
      gene: ENSG00000268903
      feature_type: Transcript
      feature: ENST00000494149
      feature_biotype: processed_pseudogene
      exon: ~
      intron: ~
      hgvsc: ~
      hgvsp: ~
      cdna_position: ~
      cds_position: ~
      protein_position: ~
      amino_acids: ~
      codons: ~
      existing_variation: ~
      dbsnp_id: "1"
      distance: "2772"
      strand: "-1"
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: Clone_based_vega_gene
      hgnc_id: ~
      canonical: true
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ~
      swissprot: ~
      trembl: ~
      uniparc: ~
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
    - allele: C
      consequence: upstream_gene_variant
      impact: MODIFIER
      symbol: RP11-34P13.16
      gene: ENSG00000269981
      feature_type: Transcript
      feature: ENST00000595919
      feature_biotype: processed_pseudogene
      exon: ~
      intron: ~
      hgvsc: ~
      hgvsp: ~
      cdna_position: ~
      cds_position: ~
      protein_position: ~
      amino_acids: ~
      codons: ~
      existing_variation: ~
      dbsnp_id: "1"
      distance: "702"
      strand: "-1"
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: Clone_based_vega_gene
      hgnc_id: ~
      canonical: true
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ~
      swissprot: ~
      trembl: ~
      uniparc: ~
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
    - allele: C
      consequence: regulatory_region_variant
      impact: MODIFIER
      symbol: ""
      gene: ""
      feature_type: RegulatoryFeature
      feature: ENSR00000668505
      feature_biotype: CTCF_binding_site
      exon: ~
      intron: ~
      hgvsc: ~
      hgvsp: ~
      cdna_position: ~
      cds_position: ~
      protein_position: ~
      amino_acids: ~
      codons: ~
      existing_variation: ~
      dbsnp_id: "1"
      distance: ~
      strand: ~
      flags: ~
      variant_class: SNV
      minimised: "1"
      symbol_source: ~
      hgnc_id: ~
      canonical: false
      tsl: ~
      appris: ~
      ccds: ~
      ensp: ~
      swissprot: ~
      trembl: ~
      uniparc: ~
      gene_pheno: ~
      sift: ~
      polyphen: ~
      domains: []
      hgvs_offset: ~
      gmaf: ~
      afr_maf: ~
      amr_maf: ~
      eas_maf: ~
      eur_maf: ~
      sas_maf: ~
      aa_maf: ~
      ea_maf: ~
      exac_maf: ~
      exac_adj_maf: ~
      exac_afr_maf: ~
      exac_amr_maf: ~
      exac_eas_maf: ~
      exac_fin_maf: ~
      exac_nfe_maf: ~
      exac_oth_maf: ~
      exac_sas_maf: ~
      clin_sig: ~
      somatic: ~
      pheno: ~
      pubmed: ~
      motif_name: ~
      motif_pos: ~
      high_inf_pos: ~
      motif_score_change: ~
      lof: ~
      lof_filter: ~
      lof_flags: ~
      lof_info: ~
  allele_counts:
    - cohort: ~
      by_population:
        - population: afr
          counts:
            overall:
              ac: 0
              an: 5228
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 2998
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 2230
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: amr
          counts:
            overall:
              ac: 0
              an: 11078
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 6056
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 5022
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              ac: 0
              an: 1536
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 856
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 680
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: eas
          counts:
            overall:
              ac: 0
              an: 7900
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 3826
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 4074
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: eas_jpn
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_oea
          counts:
            overall:
              ac: 0
              an: 6032
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_kor
          counts:
            overall:
              ac: 0
              an: 1868
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: fin
          counts:
            overall:
              ac: 0
              an: 744
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 358
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 386
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: nfe
          counts:
            overall:
              ac: 0
              an: 21110
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 10294
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 10816
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: nfe_bgr
          counts:
            overall:
              ac: 0
              an: 4
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_est
          counts:
            overall:
              ac: 0
              an: 58
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_nwe
          counts:
            overall:
              ac: 0
              an: 16862
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_onf
          counts:
            overall:
              ac: 0
              an: 4110
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_seu
          counts:
            overall:
              ac: 0
              an: 66
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_swe
          counts:
            overall:
              ac: 0
              an: 10
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: oth
          counts:
            overall:
              ac: 0
              an: 1932
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 936
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 996
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: sas
          counts:
            overall:
              ac: 1
              an: 6132
              nhomalt: 0
              af: 0.000163079
            xx:
              ac: 0
              an: 2400
              nhomalt: 0
              af: 0
            xy:
              ac: 1
              an: 3732
              nhomalt: 0
              af: 0.000267953
          faf95: 0.000008
          faf99: 0.000008
      by_sex:
        overall:
          ac: 1
          an: 55660
          nhomalt: 0
          af: 0.0000179662
        xx:
          ac: 0
          an: 27724
          nhomalt: 0
          af: 0
        xy:
          ac: 1
          an: 27936
          nhomalt: 0
          af: 0.0000357961
      raw:
        ac: 1
        an: 111004
        nhomalt: 0
        af: 0.00000900868
      popmax: sas
      af_popmax: 0.000163079
      ac_popmax: 1
      an_popmax: 6132
      nhomalt_popmax: 0
    - cohort: controls
      by_population:
        - population: afr
          counts:
            overall:
              ac: 0
              an: 2244
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 1298
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 946
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: amr
          counts:
            overall:
              ac: 0
              an: 5638
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 3180
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 2458
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              ac: 0
              an: 278
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 124
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 154
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: eas
          counts:
            overall:
              ac: 0
              an: 3872
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 1948
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 1924
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: eas_jpn
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_oea
          counts:
            overall:
              ac: 0
              an: 2944
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_kor
          counts:
            overall:
              ac: 0
              an: 928
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: fin
          counts:
            overall:
              ac: 0
              an: 26
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 14
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 12
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: nfe
          counts:
            overall:
              ac: 0
              an: 7186
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 3784
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 3402
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: nfe_bgr
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_est
          counts:
            overall:
              ac: 0
              an: 20
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_nwe
          counts:
            overall:
              ac: 0
              an: 5910
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_onf
          counts:
            overall:
              ac: 0
              an: 1254
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_seu
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_swe
          counts:
            overall:
              ac: 0
              an: 2
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: oth
          counts:
            overall:
              ac: 0
              an: 704
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 362
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 342
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: sas
          counts:
            overall:
              ac: 0
              an: 2812
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 1112
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 1700
              nhomalt: 0
              af: 0
          faf95: 0.000008
          faf99: 0.000008
      by_sex:
        overall:
          ac: 0
          an: 22760
          nhomalt: 0
          af: 0
        xx:
          ac: 0
          an: 11822
          nhomalt: 0
          af: 0
        xy:
          ac: 0
          an: 10938
          nhomalt: 0
          af: 0
      raw:
        ac: 0
        an: 44536
        nhomalt: 0
        af: 0
      popmax: ~
      af_popmax: ~
      ac_popmax: ~
      an_popmax: ~
      nhomalt_popmax: ~
    - cohort: non_cancer
      by_population:
        - population: afr
          counts:
            overall:
              ac: 0
              an: 5228
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 2998
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 2230
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: amr
          counts:
            overall:
              ac: 0
              an: 11078
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 6056
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 5022
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              ac: 0
              an: 1536
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 856
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 680
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: eas
          counts:
            overall:
              ac: 0
              an: 7900
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 3826
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 4074
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: eas_jpn
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_oea
          counts:
            overall:
              ac: 0
              an: 6032
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_kor
          counts:
            overall:
              ac: 0
              an: 1868
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: fin
          counts:
            overall:
              ac: 0
              an: 744
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 358
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 386
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: nfe
          counts:
            overall:
              ac: 0
              an: 21110
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 10294
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 10816
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: nfe_bgr
          counts:
            overall:
              ac: 0
              an: 4
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_est
          counts:
            overall:
              ac: 0
              an: 58
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_nwe
          counts:
            overall:
              ac: 0
              an: 16862
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_onf
          counts:
            overall:
              ac: 0
              an: 4110
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_seu
          counts:
            overall:
              ac: 0
              an: 66
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_swe
          counts:
            overall:
              ac: 0
              an: 10
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: oth
          counts:
            overall:
              ac: 0
              an: 1932
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 936
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 996
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: sas
          counts:
            overall:
              ac: 1
              an: 6132
              nhomalt: 0
              af: 0.000163079
            xx:
              ac: 0
              an: 2400
              nhomalt: 0
              af: 0
            xy:
              ac: 1
              an: 3732
              nhomalt: 0
              af: 0.000267953
          faf95: 0.000008
          faf99: 0.000008
      by_sex:
        overall:
          ac: 1
          an: 55660
          nhomalt: 0
          af: 0.0000179662
        xx:
          ac: 0
          an: 27724
          nhomalt: 0
          af: 0
        xy:
          ac: 1
          an: 27936
          nhomalt: 0
          af: 0.0000357961
      raw:
        ac: 1
        an: 110688
        nhomalt: 0
        af: 0.0000090344
      popmax: sas
      af_popmax: 0.000163079
      ac_popmax: 1
      an_popmax: 6132
      nhomalt_popmax: 0
    - cohort: non_neuro
      by_population:
        - population: afr
          counts:
            overall:
              ac: 0
              an: 5196
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 2984
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 2212
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: amr
          counts:
            overall:
              ac: 0
              an: 7820
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 4346
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 3474
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              ac: 0
              an: 662
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 298
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 364
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: eas
          counts:
            overall:
              ac: 0
              an: 7848
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 3790
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 4058
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: eas_jpn
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_oea
          counts:
            overall:
              ac: 0
              an: 5982
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_kor
          counts:
            overall:
              ac: 0
              an: 1866
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: fin
          counts:
            overall:
              ac: 0
              an: 514
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 196
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 318
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: nfe
          counts:
            overall:
              ac: 0
              an: 17284
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 8982
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 8302
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: nfe_bgr
          counts:
            overall:
              ac: 0
              an: 4
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_est
          counts:
            overall:
              ac: 0
              an: 50
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_nwe
          counts:
            overall:
              ac: 0
              an: 13772
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_onf
          counts:
            overall:
              ac: 0
              an: 3446
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_seu
          counts:
            overall:
              ac: 0
              an: 2
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_swe
          counts:
            overall:
              ac: 0
              an: 10
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: oth
          counts:
            overall:
              ac: 0
              an: 1544
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 794
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 750
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: sas
          counts:
            overall:
              ac: 1
              an: 6130
              nhomalt: 0
              af: 0.000163132
            xx:
              ac: 0
              an: 2400
              nhomalt: 0
              af: 0
            xy:
              ac: 1
              an: 3730
              nhomalt: 0
              af: 0.000268097
          faf95: 0.000008
          faf99: 0.000008
      by_sex:
        overall:
          ac: 1
          an: 46998
          nhomalt: 0
          af: 0.0000212775
        xx:
          ac: 0
          an: 23790
          nhomalt: 0
          af: 0
        xy:
          ac: 1
          an: 23208
          nhomalt: 0
          af: 0.0000430886
      raw:
        ac: 1
        an: 93968
        nhomalt: 0
        af: 0.0000106419
      popmax: sas
      af_popmax: 0.000163132
      ac_popmax: 1
      an_popmax: 6130
      nhomalt_popmax: 0
    - cohort: non_topmed
      by_population:
        - population: afr
          counts:
            overall:
              ac: 0
              an: 5078
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 2900
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 2178
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: amr
          counts:
            overall:
              ac: 0
              an: 11040
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 6034
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 5006
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              ac: 0
              an: 1508
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 842
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 666
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: eas
          counts:
            overall:
              ac: 0
              an: 7898
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 3826
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 4072
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: eas_jpn
          counts:
            overall: ~
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_oea
          counts:
            overall:
              ac: 0
              an: 6030
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: eas_kor
          counts:
            overall:
              ac: 0
              an: 1868
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: fin
          counts:
            overall:
              ac: 0
              an: 742
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 356
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 386
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: nfe
          counts:
            overall:
              ac: 0
              an: 20102
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 9750
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 10352
              nhomalt: 0
              af: 0
          faf95: 0
          faf99: 0
        - population: nfe_bgr
          counts:
            overall:
              ac: 0
              an: 4
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_est
          counts:
            overall:
              ac: 0
              an: 54
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_nwe
          counts:
            overall:
              ac: 0
              an: 16152
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_onf
          counts:
            overall:
              ac: 0
              an: 3816
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_seu
          counts:
            overall:
              ac: 0
              an: 66
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: nfe_swe
          counts:
            overall:
              ac: 0
              an: 10
              nhomalt: 0
              af: 0
            xx: ~
            xy: ~
          faf95: ~
          faf99: ~
        - population: oth
          counts:
            overall:
              ac: 0
              an: 1886
              nhomalt: 0
              af: 0
            xx:
              ac: 0
              an: 910
              nhomalt: 0
              af: 0
            xy:
              ac: 0
              an: 976
              nhomalt: 0
              af: 0
          faf95: ~
          faf99: ~
        - population: sas
          counts:
            overall:
              ac: 1
              an: 6132
              nhomalt: 0
              af: 0.000163079
            xx:
              ac: 0
              an: 2400
              nhomalt: 0
              af: 0
            xy:
              ac: 1
              an: 3732
              nhomalt: 0
              af: 0.000267953
          faf95: 0.000008
          faf99: 0.000008
      by_sex:
        overall:
          ac: 1
          an: 54386
          nhomalt: 0
          af: 0.0000183871
        xx:
          ac: 0
          an: 27018
          nhomalt: 0
          af: 0
        xy:
          ac: 1
          an: 27368
          nhomalt: 0
          af: 0.000036539
      raw:
        ac: 1
        an: 109674
        nhomalt: 0
        af: 0.00000911793
      popmax: sas
      af_popmax: 0.000163079
      ac_popmax: 1
      an_popmax: 6132
      nhomalt_popmax: 0
  nonpar: false
  liftover_info:
    reverse_complemented_alleles: false
    swapped_alleles: false
    original_alleles: []
    original_contig: "1"
    original_start: "138667"
  rf_info:
    rf_tp_probability: 0.0108928
    rf_positive_label: false
    rf_negative_label: false
    rf_label: ~
    rf_train: false
  variant_info:
    variant_type: snv
    allele_type: snv
    n_alt_alleles: 1
    was_mixed: false
    has_star: false
  quality_info:
    fs: 18.822
    inbreeding_coeff: -0.0435
    mq: 34.94
    mq_rank_sum: -1.023
    qd: 4.06
    read_pos_rank_sum: -0.527
    vqsr_positive_train_site: false
    vqsr_negative_train_site: false
    base_q_rank_sum: -0.581
    clipping_rank_sum: 0.03
    sor: 0.09
    dp: 4968225
    vqslod: -13.81
    vqsr_culprit: FS
    segdup: true
    lcr: false
    decoy: false
    transmitted_singleton: false
    pab_max: 0.000000000185456
  age_info:
    age_hist_hom_bin_freq: []
    age_hist_hom_n_smaller: 0
    age_hist_hom_n_larger: 0
    age_hist_het_bin_freq: []
    age_hist_het_n_smaller: 0
    age_hist_het_n_larger: 0
  depth_info:
    dp_hist_all_n_larger: 15028
    dp_hist_alt_n_larger: 1
    dp_hist_all_bin_freq: []
    dp_hist_alt_bin_freq: []

