##fileformat=VCFv4.0
##fileDate=20180419
##source=dbSNP
##dbSNP_BUILD_ID=151
##reference=GRCh37.p13
##phasing=partial
##variationPropertyDocumentationUrl=ftp://ftp.ncbi.nlm.nih.gov/snp/specs/dbSNP_BitField_latest.pdf	
##INFO=<ID=RS,Number=1,Type=Integer,Description="dbSNP ID (i.e. rs number)">
##INFO=<ID=RSPOS,Number=1,Type=Integer,Description="Chr position reported in dbSNP">
##INFO=<ID=RV,Number=0,Type=Flag,Description="RS orientation is reversed">
##INFO=<ID=VP,Number=1,Type=String,Description="Variation Property.  Documentation is at ftp://ftp.ncbi.nlm.nih.gov/snp/specs/dbSNP_BitField_latest.pdf">
##INFO=<ID=GENEINFO,Number=1,Type=String,Description="Pairs each of gene symbol:gene id.  The gene symbol and id are delimited by a colon (:) and each pair is delimited by a vertical bar (|)">
##INFO=<ID=dbSNPBuildID,Number=1,Type=Integer,Description="First dbSNP Build for RS">
##INFO=<ID=SAO,Number=1,Type=Integer,Description="Variant Allele Origin: 0 - unspecified, 1 - Germline, 2 - Somatic, 3 - Both">
##INFO=<ID=SSR,Number=1,Type=Integer,Description="Variant Suspect Reason Codes (may be more than one value added together) 0 - unspecified, 1 - Paralog, 2 - byEST, 4 - oldAlign, 8 - Para_EST, 16 - 1kg_failed, 1024 - other">
##INFO=<ID=WGT,Number=1,Type=Integer,Description="Weight, 00 - unmapped, 1 - weight 1, 2 - weight 2, 3 - weight 3 or more">
##INFO=<ID=VC,Number=1,Type=String,Description="Variation Class">
##INFO=<ID=PM,Number=0,Type=Flag,Description="Variant is Precious(Clinical,Pubmed Cited)">
##INFO=<ID=TPA,Number=0,Type=Flag,Description="Provisional Third Party Annotation(TPA) (currently rs from PHARMGKB who will give phenotype data)">
##INFO=<ID=PMC,Number=0,Type=Flag,Description="Links exist to PubMed Central article">
##INFO=<ID=S3D,Number=0,Type=Flag,Description="Has 3D structure - SNP3D table">
##INFO=<ID=SLO,Number=0,Type=Flag,Description="Has SubmitterLinkOut - From SNP->SubSNP->Batch.link_out">
##INFO=<ID=NSF,Number=0,Type=Flag,Description="Has non-synonymous frameshift A coding region variation where one allele in the set changes all downstream amino acids. FxnClass = 44">
##INFO=<ID=NSM,Number=0,Type=Flag,Description="Has non-synonymous missense A coding region variation where one allele in the set changes protein peptide. FxnClass = 42">
##INFO=<ID=NSN,Number=0,Type=Flag,Description="Has non-synonymous nonsense A coding region variation where one allele in the set changes to STOP codon (TER). FxnClass = 41">
##INFO=<ID=REF,Number=0,Type=Flag,Description="Has reference A coding region variation where one allele in the set is identical to the reference sequence. FxnCode = 8">
##INFO=<ID=SYN,Number=0,Type=Flag,Description="Has synonymous A coding region variation where one allele in the set does not change the encoded amino acid. FxnCode = 3">
##INFO=<ID=U3,Number=0,Type=Flag,Description="In 3' UTR Location is in an untranslated region (UTR). FxnCode = 53">
##INFO=<ID=U5,Number=0,Type=Flag,Description="In 5' UTR Location is in an untranslated region (UTR). FxnCode = 55">
##INFO=<ID=ASS,Number=0,Type=Flag,Description="In acceptor splice site FxnCode = 73">
##INFO=<ID=DSS,Number=0,Type=Flag,Description="In donor splice-site FxnCode = 75">
##INFO=<ID=INT,Number=0,Type=Flag,Description="In Intron FxnCode = 6">
##INFO=<ID=R3,Number=0,Type=Flag,Description="In 3' gene region FxnCode = 13">
##INFO=<ID=R5,Number=0,Type=Flag,Description="In 5' gene region FxnCode = 15">
##INFO=<ID=OTH,Number=0,Type=Flag,Description="Has other variant with exactly the same set of mapped positions on NCBI refernce assembly.">
##INFO=<ID=CFL,Number=0,Type=Flag,Description="Has Assembly conflict. This is for weight 1 and 2 variant that maps to different chromosomes on different assemblies.">
##INFO=<ID=ASP,Number=0,Type=Flag,Description="Is Assembly specific. This is set if the variant only maps to one assembly">
##INFO=<ID=MUT,Number=0,Type=Flag,Description="Is mutation (journal citation, explicit fact): a low frequency variation that is cited in journal and other reputable sources">
##INFO=<ID=VLD,Number=0,Type=Flag,Description="Is Validated.  This bit is set if the variant has 2+ minor allele count based on frequency or genotype data.">
##INFO=<ID=G5A,Number=0,Type=Flag,Description=">5% minor allele frequency in each and all populations">
##INFO=<ID=G5,Number=0,Type=Flag,Description=">5% minor allele frequency in 1+ populations">
##INFO=<ID=HD,Number=0,Type=Flag,Description="Marker is on high density genotyping kit (50K density or greater).  The variant may have phenotype associations present in dbGaP.">
##INFO=<ID=GNO,Number=0,Type=Flag,Description="Genotypes available. The variant has individual genotype (in SubInd table).">
##INFO=<ID=KGPhase1,Number=0,Type=Flag,Description="1000 Genome phase 1 (incl. June Interim phase 1)">
##INFO=<ID=KGPhase3,Number=0,Type=Flag,Description="1000 Genome phase 3">
##INFO=<ID=CDA,Number=0,Type=Flag,Description="Variation is interrogated in a clinical diagnostic assay">
##INFO=<ID=LSD,Number=0,Type=Flag,Description="Submitted from a locus-specific database">
##INFO=<ID=MTP,Number=0,Type=Flag,Description="Microattribution/third-party annotation(TPA:GWAS,PAGE)">
##INFO=<ID=OM,Number=0,Type=Flag,Description="Has OMIM/OMIA">
##INFO=<ID=NOC,Number=0,Type=Flag,Description="Contig allele not present in variant allele list. The reference sequence allele at the mapped position is not present in the variant allele list, adjusted for orientation.">
##INFO=<ID=WTD,Number=0,Type=Flag,Description="Is Withdrawn by submitter If one member ss is withdrawn by submitter, then this bit is set.  If all member ss' are withdrawn, then the rs is deleted to SNPHistory">
##INFO=<ID=NOV,Number=0,Type=Flag,Description="Rs cluster has non-overlapping allele sets. True when rs set has more than 2 alleles from different submissions and these sets share no alleles in common.">
##FILTER=<ID=NC,Description="Inconsistent Genotype Submission For At Least One Sample">
##INFO=<ID=CAF,Number=.,Type=String,Description="An ordered, comma delimited list of allele frequencies based on 1000Genomes, starting with the reference allele followed by alternate alleles as ordered in the ALT column. Where a 1000Genomes alternate allele is not in the dbSNPs alternate allele set, the allele is added to the ALT column. The minor allele is the second largest value in the list, and was previuosly reported in VCF as the GMAF. This is the GMAF reported on the RefSNP and EntrezSNP pages and VariationReporter">
##INFO=<ID=COMMON,Number=1,Type=Integer,Description="RS is a common SNP.  A common SNP is one that has at least one 1000Genomes population with a minor allele of frequency >= 1% and for which 2 or more founders contribute to that minor allele frequency.">
##INFO=<ID=TOPMED,Number=.,Type=String,Description="An ordered, comma delimited list of allele frequencies based on TOPMed, starting with the reference allele followed by alternate alleles as ordered in the ALT column. The TOPMed minor allele is the second largest value in the list.">
#CHROM	POS	ID	REF	ALT	QUAL	FILTER	INFO
17	41267746	rs80357446	C	A,T	.	.	RS=80357446;RSPOS=41267746;RV;dbSNPBuildID=132;SSR=0;SAO=1;VP=0x050168080a05000002100100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;PM;PMC;SLO;NSM;REF;INT;ASP;LSD
17	41267746	rs431825385	C	CA	.	.	RS=431825385;RSPOS=41267746;RV;dbSNPBuildID=138;SSR=0;SAO=1;VP=0x050060081205000002110200;GENEINFO=BRCA1:672;WGT=1;VC=DIV;PM;NSF;REF;INT;ASP;LSD;OM
17	41267746	rs80357951	CA	C	.	.	RS=80357951;RSPOS=41267747;RV;dbSNPBuildID=132;SSR=0;SAO=1;VP=0x050168081205000002100200;GENEINFO=BRCA1:672;WGT=1;VC=DIV;PM;PMC;SLO;NSF;REF;INT;ASP;LSD
17	41267747	rs80357327	A	C,G,T	.	.	RS=80357327;RSPOS=41267747;RV;dbSNPBuildID=132;SSR=0;SAO=1;VP=0x050168080a05000002110100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;PM;PMC;SLO;NSM;REF;INT;ASP;LSD;OM
17	41267749	rs1298544053	A	G	.	.	RS=1298544053;RSPOS=41267749;dbSNPBuildID=151;SSR=0;SAO=0;VP=0x050000080a05000002000100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;NSM;REF;INT;ASP
17	41267752	rs80357943	AT	A	.	.	RS=80357943;RSPOS=41267753;RV;dbSNPBuildID=132;SSR=0;SAO=1;VP=0x050168081205000002100200;GENEINFO=BRCA1:672;WGT=1;VC=DIV;PM;PMC;SLO;NSF;REF;INT;ASP;LSD
17	41267753	rs80357163	T	C,G	.	.	RS=80357163;RSPOS=41267753;RV;dbSNPBuildID=132;SSR=0;SAO=1;VP=0x050168080a05000002100100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;PM;PMC;SLO;NSM;REF;INT;ASP;LSD
17	41267754	rs786202211	G	A	.	.	RS=786202211;RSPOS=41267754;RV;dbSNPBuildID=144;SSR=0;SAO=1;VP=0x050060080305000002100100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;PM;REF;SYN;INT;ASP;LSD
17	41267754	rs397508847	GT	G	.	.	RS=397508847;RSPOS=41267755;RV;dbSNPBuildID=136;SSR=0;SAO=1;VP=0x050068081205000002110200;GENEINFO=BRCA1:672;WGT=1;VC=DIV;PM;PMC;NSF;REF;INT;ASP;LSD;OM
17	41267755	rs80357276	T	A,C	.	.	RS=80357276;RSPOS=41267755;RV;dbSNPBuildID=132;SSR=0;SAO=1;VP=0x050168080a05000002100100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;PM;PMC;SLO;NSM;REF;INT;ASP;LSD
17	41267756	rs1060502353	G	T	.	.	RS=1060502353;RSPOS=41267756;RV;dbSNPBuildID=150;SSR=0;SAO=0;VP=0x050060080a05000002100100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;PM;NSM;REF;INT;ASP;LSD
17	41267757	rs1060504580	G	A	.	.	RS=1060504580;RSPOS=41267757;RV;dbSNPBuildID=150;SSR=0;SAO=0;VP=0x050060080305000002100100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;PM;REF;SYN;INT;ASP;LSD
17	41267758	rs80357972	TCA	T	.	.	RS=80357972;RSPOS=41267759;RV;dbSNPBuildID=132;SSR=0;SAO=1;VP=0x050168081205000002100200;GENEINFO=BRCA1:672;WGT=1;VC=DIV;PM;PMC;SLO;NSF;REF;INT;ASP;LSD
17	41267759	rs879255290	C	T	.	.	RS=879255290;RSPOS=41267759;RV;dbSNPBuildID=147;SSR=0;SAO=0;VP=0x050068080a05000002100100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;PM;PMC;NSM;REF;INT;ASP;LSD
17	41267760	rs886040898	A	C	.	.	RS=886040898;RSPOS=41267760;RV;dbSNPBuildID=149;SSR=0;SAO=0;VP=0x050060080a05000002100100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;PM;NSM;REF;INT;ASP;LSD
17	41267761	rs80357498	C	A,T	.	.	RS=80357498;RSPOS=41267761;RV;dbSNPBuildID=132;SSR=0;SAO=1;VP=0x050168080a05000002110100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;PM;PMC;SLO;NSM;REF;INT;ASP;LSD;OM
17	41267762	rs80357164	A	C,G,T	.	.	RS=80357164;RSPOS=41267762;RV;dbSNPBuildID=132;SSR=0;SAO=1;VP=0x050168080a05000002110104;GENEINFO=BRCA1:672;WGT=1;VC=SNV;PM;PMC;SLO;NSM;REF;INT;ASP;LSD;OM;NOV
17	41267763	rs1800062	C	A,T	.	.	RS=1800062;RSPOS=41267763;RV;dbSNPBuildID=89;SSR=0;SAO=1;VP=0x050168080b05110536100100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;PM;PMC;SLO;NSM;REF;SYN;INT;ASP;G5;HD;GNO;KGPhase1;KGPhase3;LSD;CAF=0.9874,.,0.01258;COMMON=1;TOPMED=0.99660741590214067,.,0.00339258409785932
17	41267763	rs80357949	CTT	C	.	.	RS=80357949;RSPOS=41267764;RV;dbSNPBuildID=132;SSR=0;SAO=1;VP=0x050168081205000002100200;GENEINFO=BRCA1:672;WGT=1;VC=DIV;PM;PMC;SLO;NSF;REF;INT;ASP;LSD
17	41267766	rs1293537445	T	A	.	.	RS=1293537445;RSPOS=41267766;dbSNPBuildID=151;SSR=0;SAO=0;VP=0x050000080305000002000100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;REF;SYN;INT;ASP
17	41267767	rs80356880	G	C,T	.	.	RS=80356880;RSPOS=41267767;RV;dbSNPBuildID=132;SSR=0;SAO=1;VP=0x050168080a05000002100100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;PM;PMC;SLO;NSM;REF;INT;ASP;LSD;TOPMED=0.99999203618756371,0.00000796381243628,.
17	41267770	rs183557525	G	T	.	.	RS=183557525;RSPOS=41267770;dbSNPBuildID=135;SSR=0;SAO=0;VP=0x050000080a05000036000100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;NSM;REF;INT;ASP;KGPhase1;KGPhase3;CAF=0.9998,0.0001997;COMMON=0
17	41267771	rs905812561	A	T	.	.	RS=905812561;RSPOS=41267771;dbSNPBuildID=150;SSR=0;SAO=0;VP=0x050000000005000002000100;WGT=1;VC=SNV;ASP
17	41267771	rs886039920	AGACAG	A	.	.	RS=886039920;RSPOS=41267772;RV;dbSNPBuildID=149;SSR=0;SAO=0;VP=0x050060081205000002100200;GENEINFO=BRCA1:672;WGT=1;VC=DIV;PM;NSF;REF;INT;ASP;LSD
17	41267771	rs886040338	AGACAGGTT	A	.	.	RS=886040338;RSPOS=41267772;RV;dbSNPBuildID=149;SSR=0;SAO=0;VP=0x050060081205000002100200;GENEINFO=BRCA1:672;WGT=1;VC=DIV;PM;NSF;REF;INT;ASP;LSD
17	41267773	rs1235706456	A	C	.	.	RS=1235706456;RSPOS=41267773;dbSNPBuildID=151;SSR=0;SAO=0;VP=0x050000080a05000002000100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;NSM;REF;INT;ASP
17	41267774	rs879255284	C	A	.	.	RS=879255284;RSPOS=41267774;RV;dbSNPBuildID=147;SSR=0;SAO=0;VP=0x050068080a05000002100100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;PM;PMC;NSM;REF;INT;ASP;LSD
17	41267774	rs886039922	CA	C	.	.	RS=886039922;RSPOS=41267775;RV;dbSNPBuildID=149;SSR=0;SAO=0;VP=0x050060081205000002100200;GENEINFO=BRCA1:672;WGT=1;VC=DIV;PM;NSF;REF;INT;ASP;LSD
17	41267775	rs80357750	AG	A	.	.	RS=80357750;RSPOS=41267776;RV;dbSNPBuildID=132;SSR=0;SAO=1;VP=0x050168081205000002100200;GENEINFO=BRCA1:672;WGT=1;VC=DIV;PM;PMC;SLO;NSF;REF;INT;ASP;LSD
17	41267776	rs786203319	G	A	.	.	RS=786203319;RSPOS=41267776;RV;dbSNPBuildID=144;SSR=0;SAO=1;VP=0x050060080a05000002100100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;PM;NSM;REF;INT;ASP;LSD
17	41267777	rs1064793357	G	A	.	.	RS=1064793357;RSPOS=41267777;RV;dbSNPBuildID=150;SSR=0;SAO=0;VP=0x050060080a05000002100100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;PM;NSM;REF;INT;ASP;LSD
17	41267779	rs876660844	T	G	.	.	RS=876660844;RSPOS=41267779;RV;dbSNPBuildID=147;SSR=0;SAO=1;VP=0x050060080a05000002100100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;PM;NSM;REF;INT;ASP;LSD
17	41267780	rs80357066	C	G	.	.	RS=80357066;RSPOS=41267780;RV;dbSNPBuildID=132;SSR=0;SAO=1;VP=0x050168080a05000002100100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;PM;PMC;SLO;NSM;REF;INT;ASP;LSD
17	41267783	rs886040332	TG	T	.	.	RS=886040332;RSPOS=41267784;RV;dbSNPBuildID=149;SSR=0;SAO=0;VP=0x050060081205000002100200;GENEINFO=BRCA1:672;WGT=1;VC=DIV;PM;NSF;REF;INT;ASP;LSD
17	41267784	rs80357000	G	C	.	.	RS=80357000;RSPOS=41267784;RV;dbSNPBuildID=132;SSR=0;SAO=1;VP=0x050168080a05000002100100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;PM;PMC;SLO;NSM;REF;INT;ASP;LSD
17	41267788	rs397509331	A	T	.	.	RS=397509331;RSPOS=41267788;RV;dbSNPBuildID=136;SSR=0;SAO=1;VP=0x050068080605000002110100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;PM;PMC;NSN;REF;INT;ASP;LSD;OM
17	41267790	rs1343667553	C	T	.	.	RS=1343667553;RSPOS=41267790;dbSNPBuildID=151;SSR=0;SAO=0;VP=0x050000080305000002000100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;REF;SYN;INT;ASP;TOPMED=0.99999203618756371,0.00000796381243628
17	41267791	rs773841328	T	C	.	.	RS=773841328;RSPOS=41267791;dbSNPBuildID=144;SSR=0;SAO=0;VP=0x050000080a05000002000100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;NSM;REF;INT;ASP
17	41267792	rs80357443	C	A	.	.	RS=80357443;RSPOS=41267792;RV;dbSNPBuildID=132;SSR=0;SAO=1;VP=0x050168080605000002100100;GENEINFO=BRCA1:672;WGT=1;VC=SNV;PM;PMC;SLO;NSN;REF;INT;ASP;LSD
17	41267792	rs80357728	CCA	C	.	.	RS=80357728;RSPOS=41267793;RV;dbSNPBuildID=132;SSR=0;SAO=1;VP=0x050168081205000002100200;GENEINFO=BRCA1:672;WGT=1;VC=DIV;PM;PMC;SLO;NSF;REF;INT;ASP;LSD
