---
source: src/pbs/gnomad/gnomad3.rs
expression: records
---
- chrom: chr1
  pos: 15971
  refAllele: G
  altAllele: C
  vep:
    - allele: C
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: DDX11L1
      gene: ENSG00000223972
      featureType: Transcript
      feature: ENST00000450305
      featureBiotype: transcribed_unprocessed_pseudogene
      dbsnpId: "1"
      distance: "2301"
      strand: "1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:37102"
    - allele: C
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: DDX11L1
      gene: ENSG00000223972
      featureType: Transcript
      feature: ENST00000456328
      featureBiotype: processed_transcript
      dbsnpId: "1"
      distance: "1562"
      strand: "1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:37102"
      canonical: true
      tsl: 1
    - allele: C
      consequence: intron_variant&non_coding_transcript_variant
      impact: MODIFIER
      symbol: WASH7P
      gene: ENSG00000227232
      featureType: Transcript
      feature: ENST00000488147
      featureBiotype: unprocessed_pseudogene
      intron: 8/10
      hgvsc: "ENST00000488147.1:n.1068-24C>G"
      dbsnpId: "1"
      strand: "-1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:38034"
      canonical: true
    - allele: C
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: MIR6859-1
      gene: ENSG00000278267
      featureType: Transcript
      feature: ENST00000619216
      featureBiotype: miRNA
      dbsnpId: "1"
      distance: "1398"
      strand: "-1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:50039"
      canonical: true
    - allele: C
      consequence: intron_variant&non_coding_transcript_variant
      impact: MODIFIER
      symbol: WASH7P
      gene: "653635"
      featureType: Transcript
      feature: NR_024540.1
      featureBiotype: transcribed_pseudogene
      intron: 8/10
      hgvsc: "NR_024540.1:n.1081-24C>G"
      dbsnpId: "1"
      strand: "-1"
      variantClass: SNV
      symbolSource: EntrezGene
      hgncId: "HGNC:38034"
      canonical: true
    - allele: C
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: DDX11L1
      gene: "100287102"
      featureType: Transcript
      feature: NR_046018.2
      featureBiotype: transcribed_pseudogene
      dbsnpId: "1"
      distance: "1562"
      strand: "1"
      variantClass: SNV
      symbolSource: EntrezGene
      hgncId: "HGNC:37102"
      canonical: true
    - allele: C
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: MIR6859-1
      gene: "102466751"
      featureType: Transcript
      feature: NR_106918.1
      featureBiotype: miRNA
      dbsnpId: "1"
      distance: "1398"
      strand: "-1"
      variantClass: SNV
      symbolSource: EntrezGene
      hgncId: "HGNC:50039"
      canonical: true
    - allele: C
      consequence: regulatory_region_variant
      impact: MODIFIER
      featureType: RegulatoryFeature
      feature: ENSR00000344266
      featureBiotype: CTCF_binding_site
      dbsnpId: "1"
      variantClass: SNV
  alleleCounts:
    - byPopulation:
        - population: afr
          counts:
            overall:
              an: 37056
            xx:
              an: 19882
            xy:
              an: 17174
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 624
            xx:
              an: 312
            xy:
              an: 312
        - population: amr
          counts:
            overall:
              ac: 1
              an: 9554
              af: 0.000104668
            xx:
              an: 4306
            xy:
              ac: 1
              an: 5248
              af: 0.000190549
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 2268
            xx:
              an: 1238
            xy:
              an: 1030
        - population: eas
          counts:
            overall:
              an: 4626
            xx:
              an: 2054
            xy:
              an: 2572
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 5348
            xx:
              an: 1470
            xy:
              an: 3878
        - population: mid
          counts:
            overall:
              an: 238
            xx:
              an: 134
            xy:
              an: 104
        - population: nfe
          counts:
            overall:
              an: 45876
            xx:
              an: 26958
            xy:
              an: 18918
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1392
            xx:
              an: 706
            xy:
              an: 686
        - population: sas
          counts:
            overall:
              an: 3074
            xx:
              an: 760
            xy:
              an: 2314
          faf95: 0
          faf99: 0
      bySex:
        overall:
          ac: 1
          an: 110056
          af: 0.00000908628
        xx:
          an: 57820
        xy:
          ac: 1
          an: 52236
          af: 0.0000191439
      raw:
        ac: 1
        an: 134496
        af: 0.00000743517
      popmax: amr
      afPopmax: 0.000104668
      acPopmax: 1
      anPopmax: 9554
      nhomaltPopmax: 0
    - cohort: controls_and_biobanks
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 8100
            xx:
              an: 4202
            xy:
              an: 3898
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 30
            xx:
              an: 12
            xy:
              an: 18
        - population: amr
          counts:
            overall:
              an: 3254
            xx:
              an: 1720
            xy:
              an: 1534
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 84
            xx:
              an: 54
            xy:
              an: 30
        - population: eas
          counts:
            overall:
              an: 2224
            xx:
              an: 946
            xy:
              an: 1278
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 2642
            xx:
              an: 324
            xy:
              an: 2318
        - population: mid
          counts:
            overall:
              an: 188
            xx:
              an: 108
            xy:
              an: 80
        - population: nfe
          counts:
            overall:
              an: 4658
            xx:
              an: 2270
            xy:
              an: 2388
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 548
            xx:
              an: 284
            xy:
              an: 264
        - population: sas
          counts:
            overall:
              an: 2124
            xx:
              an: 602
            xy:
              an: 1522
          faf95: 0
          faf99: 0
      bySex:
        overall:
          an: 23852
        xx:
          an: 10522
        xy:
          an: 13330
      raw:
        an: 28694
    - cohort: non_cancer
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 36760
            xx:
              an: 19740
            xy:
              an: 17020
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 624
            xx:
              an: 312
            xy:
              an: 312
        - population: amr
          counts:
            overall:
              ac: 1
              an: 9438
              af: 0.000105955
            xx:
              an: 4276
            xy:
              ac: 1
              an: 5162
              af: 0.000193723
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 2158
            xx:
              an: 1154
            xy:
              an: 1004
        - population: eas
          counts:
            overall:
              an: 4416
            xx:
              an: 1964
            xy:
              an: 2452
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 5348
            xx:
              an: 1470
            xy:
              an: 3878
        - population: mid
          counts:
            overall:
              an: 228
            xx:
              an: 130
            xy:
              an: 98
        - population: nfe
          counts:
            overall:
              an: 43706
            xx:
              an: 26112
            xy:
              an: 17594
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1344
            xx:
              an: 686
            xy:
              an: 658
        - population: sas
          counts:
            overall:
              an: 3046
            xx:
              an: 744
            xy:
              an: 2302
          faf95: 0
          faf99: 0
      bySex:
        overall:
          ac: 1
          an: 107068
          af: 0.00000933986
        xx:
          an: 56588
        xy:
          ac: 1
          an: 50480
          af: 0.0000198098
      raw:
        ac: 1
        an: 130996
        af: 0.00000763382
    - cohort: non_neuro
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 29184
            xx:
              an: 16880
            xy:
              an: 12304
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 594
            xx:
              an: 286
            xy:
              an: 308
        - population: amr
          counts:
            overall:
              ac: 1
              an: 9312
              af: 0.000107388
            xx:
              an: 4208
            xy:
              ac: 1
              an: 5104
              af: 0.000195925
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 2220
            xx:
              an: 1218
            xy:
              an: 1002
        - population: eas
          counts:
            overall:
              an: 4626
            xx:
              an: 2054
            xy:
              an: 2572
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 3366
            xx:
              an: 416
            xy:
              an: 2950
        - population: mid
          counts:
            overall:
              an: 236
            xx:
              an: 134
            xy:
              an: 102
        - population: nfe
          counts:
            overall:
              an: 43372
            xx:
              an: 25940
            xy:
              an: 17432
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1328
            xx:
              an: 678
            xy:
              an: 650
        - population: sas
          counts:
            overall:
              an: 3074
            xx:
              an: 760
            xy:
              an: 2314
          faf95: 0
          faf99: 0
      bySex:
        overall:
          ac: 1
          an: 97312
          af: 0.0000102762
        xx:
          an: 52574
        xy:
          ac: 1
          an: 44738
          af: 0.0000223524
      raw:
        ac: 1
        an: 118850
        af: 0.00000841397
    - cohort: non_topmed
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 21914
            xx:
              an: 10532
            xy:
              an: 11382
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 60
            xx:
              an: 38
            xy:
              an: 22
        - population: amr
          counts:
            overall:
              an: 8056
            xx:
              an: 3394
            xy:
              an: 4662
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 650
            xx:
              an: 176
            xy:
              an: 474
        - population: eas
          counts:
            overall:
              an: 3298
            xx:
              an: 1252
            xy:
              an: 2046
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 5278
            xx:
              an: 1426
            xy:
              an: 3852
        - population: mid
          counts:
            overall:
              an: 206
            xx:
              an: 116
            xy:
              an: 90
        - population: nfe
          counts:
            overall:
              an: 13400
            xx:
              an: 5830
            xy:
              an: 7570
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 978
            xx:
              an: 460
            xy:
              an: 518
        - population: sas
          counts:
            overall:
              an: 3060
            xx:
              an: 758
            xy:
              an: 2302
          faf95: 0
          faf99: 0
      bySex:
        overall:
          an: 56900
        xx:
          an: 23982
        xy:
          an: 32918
      raw:
        an: 70334
    - cohort: non_v2
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 25570
            xx:
              an: 14150
            xy:
              an: 11420
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 624
            xx:
              an: 312
            xy:
              an: 312
        - population: amr
          counts:
            overall:
              ac: 1
              an: 8568
              af: 0.000116713
            xx:
              an: 3810
            xy:
              ac: 1
              an: 4758
              af: 0.000210172
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 2028
            xx:
              an: 1130
            xy:
              an: 898
        - population: eas
          counts:
            overall:
              an: 2500
            xx:
              an: 1186
            xy:
              an: 1314
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 3404
            xx:
              an: 606
            xy:
              an: 2798
        - population: mid
          counts:
            overall:
              an: 230
            xx:
              an: 132
            xy:
              an: 98
        - population: nfe
          counts:
            overall:
              an: 35656
            xx:
              an: 22250
            xy:
              an: 13406
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1248
            xx:
              an: 640
            xy:
              an: 608
        - population: sas
          counts:
            overall:
              an: 2348
            xx:
              an: 466
            xy:
              an: 1882
          faf95: 0
          faf99: 0
      bySex:
        overall:
          ac: 1
          an: 82176
          af: 0.000012169
        xx:
          an: 44682
        xy:
          ac: 1
          an: 37494
          af: 0.0000266709
      raw:
        ac: 1
        an: 100494
        af: 0.00000995084
  effectInfo:
    caddPhred: 5.837
  variantInfo:
    variantType: multi-snv
    alleleType: snv
    nAltAlleles: 2
    varDp: 2
  qualityInfo:
    asFs: 18.3769
    inbreedingCoeff: -0.00000751019
    asMq: 45.4443
    mqRankSum: 2.079
    asMqRankSum: 2.079
    asQd: 8.72
    readPosRankSum: 0.124
    asReadPosRankSum: 0.124
    asSor: 0.160635
    negativeTrainSite: true
    asVqslod: -3.027
    asCulprit: AS_FS
    asPabMax: 0.647606
    asQualApprox: 1308
    asSbTable: "76"
  ageInfo:
    ageHistHomNSmaller: 0
    ageHistHomNLarger: 0
    ageHistHetNSmaller: 0
    ageHistHetNLarger: 0
  depthInfo:
    dpHistAllNLarger: 559
    dpHistAltNLarger: 0
- chrom: chr1
  pos: 15973
  refAllele: G
  altAllele: A
  vep:
    - allele: A
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: DDX11L1
      gene: ENSG00000223972
      featureType: Transcript
      feature: ENST00000450305
      featureBiotype: transcribed_unprocessed_pseudogene
      dbsnpId: "1"
      distance: "2303"
      strand: "1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:37102"
    - allele: A
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: DDX11L1
      gene: ENSG00000223972
      featureType: Transcript
      feature: ENST00000456328
      featureBiotype: processed_transcript
      dbsnpId: "1"
      distance: "1564"
      strand: "1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:37102"
      canonical: true
      tsl: 1
    - allele: A
      consequence: intron_variant&non_coding_transcript_variant
      impact: MODIFIER
      symbol: WASH7P
      gene: ENSG00000227232
      featureType: Transcript
      feature: ENST00000488147
      featureBiotype: unprocessed_pseudogene
      intron: 8/10
      hgvsc: "ENST00000488147.1:n.1068-26C>T"
      dbsnpId: "1"
      strand: "-1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:38034"
      canonical: true
    - allele: A
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: MIR6859-1
      gene: ENSG00000278267
      featureType: Transcript
      feature: ENST00000619216
      featureBiotype: miRNA
      dbsnpId: "1"
      distance: "1396"
      strand: "-1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:50039"
      canonical: true
    - allele: A
      consequence: intron_variant&non_coding_transcript_variant
      impact: MODIFIER
      symbol: WASH7P
      gene: "653635"
      featureType: Transcript
      feature: NR_024540.1
      featureBiotype: transcribed_pseudogene
      intron: 8/10
      hgvsc: "NR_024540.1:n.1081-26C>T"
      dbsnpId: "1"
      strand: "-1"
      variantClass: SNV
      symbolSource: EntrezGene
      hgncId: "HGNC:38034"
      canonical: true
    - allele: A
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: DDX11L1
      gene: "100287102"
      featureType: Transcript
      feature: NR_046018.2
      featureBiotype: transcribed_pseudogene
      dbsnpId: "1"
      distance: "1564"
      strand: "1"
      variantClass: SNV
      symbolSource: EntrezGene
      hgncId: "HGNC:37102"
      canonical: true
    - allele: A
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: MIR6859-1
      gene: "102466751"
      featureType: Transcript
      feature: NR_106918.1
      featureBiotype: miRNA
      dbsnpId: "1"
      distance: "1396"
      strand: "-1"
      variantClass: SNV
      symbolSource: EntrezGene
      hgncId: "HGNC:50039"
      canonical: true
    - allele: A
      consequence: regulatory_region_variant
      impact: MODIFIER
      featureType: RegulatoryFeature
      feature: ENSR00000344266
      featureBiotype: CTCF_binding_site
      dbsnpId: "1"
      variantClass: SNV
  alleleCounts:
    - byPopulation:
        - population: afr
          counts:
            overall:
              ac: 2
              an: 37068
              af: 0.0000539549
            xx:
              ac: 2
              an: 19888
              af: 0.000100563
            xy:
              an: 17180
          faf95: 0.00000894
          faf99: 0.00000334
        - population: ami
          counts:
            overall:
              an: 628
            xx:
              an: 314
            xy:
              an: 314
        - population: amr
          counts:
            overall:
              an: 9626
            xx:
              an: 4332
            xy:
              an: 5294
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 2276
            xx:
              an: 1242
            xy:
              an: 1034
        - population: eas
          counts:
            overall:
              an: 4652
            xx:
              an: 2060
            xy:
              an: 2592
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 5366
            xx:
              an: 1466
            xy:
              an: 3900
        - population: mid
          counts:
            overall:
              an: 240
            xx:
              an: 136
            xy:
              an: 104
        - population: nfe
          counts:
            overall:
              an: 46074
            xx:
              an: 27052
            xy:
              an: 19022
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1390
            xx:
              an: 706
            xy:
              an: 684
        - population: sas
          counts:
            overall:
              an: 3084
            xx:
              an: 754
            xy:
              an: 2330
          faf95: 0
          faf99: 0
      bySex:
        overall:
          ac: 2
          an: 110404
          af: 0.0000181153
        xx:
          ac: 2
          an: 57950
          af: 0.0000345125
        xy:
          an: 52454
      raw:
        ac: 4
        an: 134654
        af: 0.0000297058
      popmax: afr
      afPopmax: 0.0000539549
      acPopmax: 2
      anPopmax: 37068
      nhomaltPopmax: 0
    - cohort: controls_and_biobanks
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 8100
            xx:
              an: 4200
            xy:
              an: 3900
          faf95: 0.00000894
          faf99: 0.00000334
        - population: ami
          counts:
            overall:
              an: 30
            xx:
              an: 12
            xy:
              an: 18
        - population: amr
          counts:
            overall:
              an: 3266
            xx:
              an: 1728
            xy:
              an: 1538
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 84
            xx:
              an: 54
            xy:
              an: 30
        - population: eas
          counts:
            overall:
              an: 2234
            xx:
              an: 950
            xy:
              an: 1284
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 2656
            xx:
              an: 326
            xy:
              an: 2330
        - population: mid
          counts:
            overall:
              an: 190
            xx:
              an: 110
            xy:
              an: 80
        - population: nfe
          counts:
            overall:
              an: 4692
            xx:
              an: 2280
            xy:
              an: 2412
          faf95: 0
          faf99: 0
        - population: oth
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            overall:
              an: 546
            xx:
              an: 282
            xy:
              an: 264
        - population: sas
          counts:
            overall:
              an: 2134
            xx:
              an: 604
            xy:
              an: 1530
          faf95: 0
          faf99: 0
      bySex:
        overall:
          an: 23932
        xx:
          an: 10546
        xy:
          an: 13386
      raw:
        ac: 1
        an: 28778
        af: 0.0000347488
    - cohort: non_cancer
      byPopulation:
        - population: afr
          counts:
            overall:
              ac: 2
              an: 36772
              af: 0.0000543892
            xx:
              ac: 2
              an: 19746
              af: 0.000101286
            xy:
              an: 17026
          faf95: 0.00000894
          faf99: 0.00000334
        - population: ami
          counts:
            overall:
              an: 628
            xx:
              an: 314
            xy:
              an: 314
        - population: amr
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            overall:
              an: 9504
            xx:
              an: 4300
            xy:
              an: 5204
          faf95: 0
          faf99: 0
        - population: asj
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            overall:
              an: 2166
            xx:
              an: 1158
            xy:
              an: 1008
        - population: eas
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              an: 4438
            xx:
              an: 1970
            xy:
              an: 2468
          faf95: 0
          faf99: 0
        - population: fin
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              an: 5366
            xx:
              an: 1466
            xy:
              an: 3900
        - population: mid
          counts:
            overall:
              an: 230
            xx:
              an: 132
            xy:
              an: 98
        - population: nfe
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            overall:
              an: 43888
            xx:
              an: 26206
            xy:
              an: 17682
          faf95: 0
          faf99: 0
        - population: oth
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            overall:
              an: 1342
            xx:
              an: 686
            xy:
              an: 656
        - population: sas
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              an: 3056
            xx:
              an: 738
            xy:
              an: 2318
          faf95: 0
          faf99: 0
      bySex:
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          an: 107390
          af: 0.0000186237
        xx:
          ac: 2
          an: 56716
          af: 0.0000352634
        xy:
          an: 50674
      raw:
        ac: 4
        an: 131136
        af: 0.0000305027
    - cohort: non_neuro
      byPopulation:
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          counts:
            overall:
              ac: 2
              an: 29190
              af: 0.0000685166
            xx:
              ac: 2
              an: 16886
              af: 0.000118441
            xy:
              an: 12304
          faf95: 0.00000894
          faf99: 0.00000334
        - population: ami
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            xx:
              an: 288
            xy:
              an: 310
        - population: amr
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            xx:
              an: 4230
            xy:
              an: 5148
          faf95: 0
          faf99: 0
        - population: asj
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            xx:
              an: 1220
            xy:
              an: 1006
        - population: eas
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            xx:
              an: 2060
            xy:
              an: 2592
          faf95: 0
          faf99: 0
        - population: fin
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            xx:
              an: 420
            xy:
              an: 2968
        - population: mid
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              an: 238
            xx:
              an: 136
            xy:
              an: 102
        - population: nfe
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            xx:
              an: 26032
            xy:
              an: 17528
          faf95: 0
          faf99: 0
        - population: oth
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            overall:
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            xx:
              an: 676
            xy:
              an: 648
        - population: sas
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              an: 3084
            xx:
              an: 754
            xy:
              an: 2330
          faf95: 0
          faf99: 0
      bySex:
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          an: 97638
          af: 0.0000204838
        xx:
          ac: 2
          an: 52702
          af: 0.0000379492
        xy:
          an: 44936
      raw:
        ac: 4
        an: 118984
        af: 0.000033618
    - cohort: non_topmed
      byPopulation:
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          counts:
            overall:
              an: 21934
            xx:
              an: 10540
            xy:
              an: 11394
          faf95: 0.00000894
          faf99: 0.00000334
        - population: ami
          counts:
            overall:
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            xx:
              an: 38
            xy:
              an: 22
        - population: amr
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              an: 8120
            xx:
              an: 3416
            xy:
              an: 4704
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 654
            xx:
              an: 178
            xy:
              an: 476
        - population: eas
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              an: 3318
            xx:
              an: 1254
            xy:
              an: 2064
          faf95: 0
          faf99: 0
        - population: fin
          counts:
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              an: 5296
            xx:
              an: 1422
            xy:
              an: 3874
        - population: mid
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            overall:
              an: 208
            xx:
              an: 118
            xy:
              an: 90
        - population: nfe
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              an: 13464
            xx:
              an: 5850
            xy:
              an: 7614
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 980
            xx:
              an: 464
            xy:
              an: 516
        - population: sas
          counts:
            overall:
              an: 3070
            xx:
              an: 752
            xy:
              an: 2318
          faf95: 0
          faf99: 0
      bySex:
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        xx:
          an: 24032
        xy:
          an: 33072
      raw:
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        an: 70476
        af: 0.0000141892
    - cohort: non_v2
      byPopulation:
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          counts:
            overall:
              ac: 1
              an: 25588
              af: 0.0000390808
            xx:
              ac: 1
              an: 14164
              af: 0.0000706015
            xy:
              an: 11424
          faf95: 0.00000894
          faf99: 0.00000334
        - population: ami
          counts:
            overall:
              an: 628
            xx:
              an: 314
            xy:
              an: 314
        - population: amr
          counts:
            overall:
              an: 8634
            xx:
              an: 3834
            xy:
              an: 4800
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 2034
            xx:
              an: 1134
            xy:
              an: 900
        - population: eas
          counts:
            overall:
              an: 2520
            xx:
              an: 1188
            xy:
              an: 1332
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 3426
            xx:
              an: 604
            xy:
              an: 2822
        - population: mid
          counts:
            overall:
              an: 232
            xx:
              an: 134
            xy:
              an: 98
        - population: nfe
          counts:
            overall:
              an: 35796
            xx:
              an: 22314
            xy:
              an: 13482
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1244
            xx:
              an: 638
            xy:
              an: 606
        - population: sas
          counts:
            overall:
              an: 2356
            xx:
              an: 460
            xy:
              an: 1896
          faf95: 0
          faf99: 0
      bySex:
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          an: 82458
          af: 0.0000121274
        xx:
          ac: 1
          an: 44784
          af: 0.0000223294
        xy:
          an: 37674
      raw:
        ac: 2
        an: 100600
        af: 0.0000198807
  effectInfo:
    caddPhred: 5.483
  variantInfo:
    variantType: multi-snv
    alleleType: snv
    nAltAlleles: 3
    varDp: 3
  qualityInfo:
    asFs: 5.44066
    inbreedingCoeff: -0.0000296831
    asMq: 45.042
    mqRankSum: -0.355
    asMqRankSum: -0.717
    asQd: 4.3829
    readPosRankSum: -0.536
    asReadPosRankSum: -0.536
    asSor: 1.10954
    negativeTrainSite: true
    asVqslod: -2.257
    asCulprit: AS_QD
    asPabMax: 1
    asQualApprox: 1179
    asSbTable: "158"
  ageInfo:
    ageHistHomNSmaller: 0
    ageHistHomNLarger: 0
    ageHistHetNSmaller: 0
    ageHistHetNLarger: 0
  depthInfo:
    dpHistAllNLarger: 559
    dpHistAltNLarger: 0
- chrom: chr1
  pos: 15973
  refAllele: G
  altAllele: C
  vep:
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      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: DDX11L1
      gene: ENSG00000223972
      featureType: Transcript
      feature: ENST00000450305
      featureBiotype: transcribed_unprocessed_pseudogene
      dbsnpId: "1"
      distance: "2303"
      strand: "1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:37102"
    - allele: C
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: DDX11L1
      gene: ENSG00000223972
      featureType: Transcript
      feature: ENST00000456328
      featureBiotype: processed_transcript
      dbsnpId: "1"
      distance: "1564"
      strand: "1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:37102"
      canonical: true
      tsl: 1
    - allele: C
      consequence: intron_variant&non_coding_transcript_variant
      impact: MODIFIER
      symbol: WASH7P
      gene: ENSG00000227232
      featureType: Transcript
      feature: ENST00000488147
      featureBiotype: unprocessed_pseudogene
      intron: 8/10
      hgvsc: "ENST00000488147.1:n.1068-26C>G"
      dbsnpId: "1"
      strand: "-1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:38034"
      canonical: true
    - allele: C
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: MIR6859-1
      gene: ENSG00000278267
      featureType: Transcript
      feature: ENST00000619216
      featureBiotype: miRNA
      dbsnpId: "1"
      distance: "1396"
      strand: "-1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:50039"
      canonical: true
    - allele: C
      consequence: intron_variant&non_coding_transcript_variant
      impact: MODIFIER
      symbol: WASH7P
      gene: "653635"
      featureType: Transcript
      feature: NR_024540.1
      featureBiotype: transcribed_pseudogene
      intron: 8/10
      hgvsc: "NR_024540.1:n.1081-26C>G"
      dbsnpId: "1"
      strand: "-1"
      variantClass: SNV
      symbolSource: EntrezGene
      hgncId: "HGNC:38034"
      canonical: true
    - allele: C
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: DDX11L1
      gene: "100287102"
      featureType: Transcript
      feature: NR_046018.2
      featureBiotype: transcribed_pseudogene
      dbsnpId: "1"
      distance: "1564"
      strand: "1"
      variantClass: SNV
      symbolSource: EntrezGene
      hgncId: "HGNC:37102"
      canonical: true
    - allele: C
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: MIR6859-1
      gene: "102466751"
      featureType: Transcript
      feature: NR_106918.1
      featureBiotype: miRNA
      dbsnpId: "1"
      distance: "1396"
      strand: "-1"
      variantClass: SNV
      symbolSource: EntrezGene
      hgncId: "HGNC:50039"
      canonical: true
    - allele: C
      consequence: regulatory_region_variant
      impact: MODIFIER
      featureType: RegulatoryFeature
      feature: ENSR00000344266
      featureBiotype: CTCF_binding_site
      dbsnpId: "1"
      variantClass: SNV
  alleleCounts:
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          counts:
            overall:
              an: 37070
            xx:
              an: 19888
            xy:
              an: 17182
          faf95: 0
          faf99: 0
        - population: ami
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            xx:
              an: 314
            xy:
              an: 314
        - population: amr
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              ac: 2
              an: 9626
              af: 0.000207771
            xx:
              an: 4332
            xy:
              ac: 2
              an: 5294
              af: 0.000377786
          faf95: 0.00003622
          faf99: 0.00001477
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            overall:
              an: 2276
            xx:
              an: 1242
            xy:
              an: 1034
        - population: eas
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            overall:
              an: 4652
            xx:
              an: 2060
            xy:
              an: 2592
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 5366
            xx:
              an: 1466
            xy:
              an: 3900
        - population: mid
          counts:
            overall:
              an: 240
            xx:
              an: 136
            xy:
              an: 104
        - population: nfe
          counts:
            overall:
              an: 46074
            xx:
              an: 27052
            xy:
              an: 19022
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1390
            xx:
              an: 706
            xy:
              an: 684
        - population: sas
          counts:
            overall:
              an: 3084
            xx:
              an: 754
            xy:
              an: 2330
          faf95: 0
          faf99: 0
      bySex:
        overall:
          ac: 2
          an: 110406
          af: 0.000018115
        xx:
          an: 57950
        xy:
          ac: 2
          an: 52456
          af: 0.0000381272
      raw:
        ac: 6
        an: 134654
        nhomalt: 1
        af: 0.0000445586
      popmax: amr
      afPopmax: 0.000207771
      acPopmax: 2
      anPopmax: 9626
      nhomaltPopmax: 0
    - cohort: controls_and_biobanks
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 8100
            xx:
              an: 4200
            xy:
              an: 3900
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 30
            xx:
              an: 12
            xy:
              an: 18
        - population: amr
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            overall:
              an: 3266
            xx:
              an: 1728
            xy:
              an: 1538
          faf95: 0.00003622
          faf99: 0.00001477
        - population: asj
          counts:
            overall:
              an: 84
            xx:
              an: 54
            xy:
              an: 30
        - population: eas
          counts:
            overall:
              an: 2234
            xx:
              an: 950
            xy:
              an: 1284
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 2656
            xx:
              an: 326
            xy:
              an: 2330
        - population: mid
          counts:
            overall:
              an: 190
            xx:
              an: 110
            xy:
              an: 80
        - population: nfe
          counts:
            overall:
              an: 4692
            xx:
              an: 2280
            xy:
              an: 2412
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 546
            xx:
              an: 282
            xy:
              an: 264
        - population: sas
          counts:
            overall:
              an: 2134
            xx:
              an: 604
            xy:
              an: 1530
          faf95: 0
          faf99: 0
      bySex:
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          an: 23932
        xx:
          an: 10546
        xy:
          an: 13386
      raw:
        an: 28778
    - cohort: non_cancer
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 36774
            xx:
              an: 19746
            xy:
              an: 17028
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 628
            xx:
              an: 314
            xy:
              an: 314
        - population: amr
          counts:
            overall:
              ac: 2
              an: 9504
              af: 0.000210438
            xx:
              an: 4300
            xy:
              ac: 2
              an: 5204
              af: 0.00038432
          faf95: 0.00003622
          faf99: 0.00001477
        - population: asj
          counts:
            overall:
              an: 2166
            xx:
              an: 1158
            xy:
              an: 1008
        - population: eas
          counts:
            overall:
              an: 4438
            xx:
              an: 1970
            xy:
              an: 2468
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 5366
            xx:
              an: 1466
            xy:
              an: 3900
        - population: mid
          counts:
            overall:
              an: 230
            xx:
              an: 132
            xy:
              an: 98
        - population: nfe
          counts:
            overall:
              an: 43888
            xx:
              an: 26206
            xy:
              an: 17682
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1342
            xx:
              an: 686
            xy:
              an: 656
        - population: sas
          counts:
            overall:
              an: 3056
            xx:
              an: 738
            xy:
              an: 2318
          faf95: 0
          faf99: 0
      bySex:
        overall:
          ac: 2
          an: 107392
          af: 0.0000186234
        xx:
          an: 56716
        xy:
          ac: 2
          an: 50676
          af: 0.0000394664
      raw:
        ac: 6
        an: 131136
        nhomalt: 1
        af: 0.000045754
    - cohort: non_neuro
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 29192
            xx:
              an: 16886
            xy:
              an: 12306
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 598
            xx:
              an: 288
            xy:
              an: 310
        - population: amr
          counts:
            overall:
              ac: 2
              an: 9378
              af: 0.000213265
            xx:
              an: 4230
            xy:
              ac: 2
              an: 5148
              af: 0.0003885
          faf95: 0.00003622
          faf99: 0.00001477
        - population: asj
          counts:
            overall:
              an: 2226
            xx:
              an: 1220
            xy:
              an: 1006
        - population: eas
          counts:
            overall:
              an: 4652
            xx:
              an: 2060
            xy:
              an: 2592
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 3388
            xx:
              an: 420
            xy:
              an: 2968
        - population: mid
          counts:
            overall:
              an: 238
            xx:
              an: 136
            xy:
              an: 102
        - population: nfe
          counts:
            overall:
              an: 43560
            xx:
              an: 26032
            xy:
              an: 17528
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1324
            xx:
              an: 676
            xy:
              an: 648
        - population: sas
          counts:
            overall:
              an: 3084
            xx:
              an: 754
            xy:
              an: 2330
          faf95: 0
          faf99: 0
      bySex:
        overall:
          ac: 2
          an: 97640
          af: 0.0000204834
        xx:
          an: 52702
        xy:
          ac: 2
          an: 44938
          af: 0.0000445058
      raw:
        ac: 6
        an: 118984
        nhomalt: 1
        af: 0.0000504269
    - cohort: non_topmed
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 21934
            xx:
              an: 10540
            xy:
              an: 11394
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 60
            xx:
              an: 38
            xy:
              an: 22
        - population: amr
          counts:
            overall:
              ac: 2
              an: 8120
              af: 0.000246305
            xx:
              an: 3416
            xy:
              ac: 2
              an: 4704
              af: 0.00042517
          faf95: 0.00003622
          faf99: 0.00001477
        - population: asj
          counts:
            overall:
              an: 654
            xx:
              an: 178
            xy:
              an: 476
        - population: eas
          counts:
            overall:
              an: 3318
            xx:
              an: 1254
            xy:
              an: 2064
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 5296
            xx:
              an: 1422
            xy:
              an: 3874
        - population: mid
          counts:
            overall:
              an: 208
            xx:
              an: 118
            xy:
              an: 90
        - population: nfe
          counts:
            overall:
              an: 13464
            xx:
              an: 5850
            xy:
              an: 7614
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 980
            xx:
              an: 464
            xy:
              an: 516
        - population: sas
          counts:
            overall:
              an: 3070
            xx:
              an: 752
            xy:
              an: 2318
          faf95: 0
          faf99: 0
      bySex:
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          an: 57104
          af: 0.0000350238
        xx:
          an: 24032
        xy:
          ac: 2
          an: 33072
          af: 0.0000604741
      raw:
        ac: 5
        an: 70476
        nhomalt: 1
        af: 0.0000709461
    - cohort: non_v2
      byPopulation:
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          counts:
            overall:
              an: 25590
            xx:
              an: 14164
            xy:
              an: 11426
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 628
            xx:
              an: 314
            xy:
              an: 314
        - population: amr
          counts:
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              ac: 2
              an: 8634
              af: 0.000231642
            xx:
              an: 3834
            xy:
              ac: 2
              an: 4800
              af: 0.000416667
          faf95: 0.00003622
          faf99: 0.00001477
        - population: asj
          counts:
            overall:
              an: 2034
            xx:
              an: 1134
            xy:
              an: 900
        - population: eas
          counts:
            overall:
              an: 2520
            xx:
              an: 1188
            xy:
              an: 1332
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 3426
            xx:
              an: 604
            xy:
              an: 2822
        - population: mid
          counts:
            overall:
              an: 232
            xx:
              an: 134
            xy:
              an: 98
        - population: nfe
          counts:
            overall:
              an: 35796
            xx:
              an: 22314
            xy:
              an: 13482
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1244
            xx:
              an: 638
            xy:
              an: 606
        - population: sas
          counts:
            overall:
              an: 2356
            xx:
              an: 460
            xy:
              an: 1896
          faf95: 0
          faf99: 0
      bySex:
        overall:
          ac: 2
          an: 82460
          af: 0.0000242542
        xx:
          an: 44784
        xy:
          ac: 2
          an: 37676
          af: 0.0000530842
      raw:
        ac: 4
        an: 100600
        af: 0.0000397614
  effectInfo:
    caddPhred: 5.063
  variantInfo:
    variantType: multi-snv
    alleleType: snv
    nAltAlleles: 3
    varDp: 3
  qualityInfo:
    asFs: 3.55669
    inbreedingCoeff: 0.333304
    asMq: 37.123
    mqRankSum: -0.355
    asMqRankSum: -0.151
    asQd: 15.5085
    readPosRankSum: -0.536
    asReadPosRankSum: -0.259
    asSor: 1.02889
    negativeTrainSite: true
    asVqslod: -2.5191
    asCulprit: AS_MQ
    asPabMax: 1
    asQualApprox: 915
    asSbTable: "158"
  ageInfo:
    ageHistHomNSmaller: 0
    ageHistHomNLarger: 0
    ageHistHetNSmaller: 0
    ageHistHetNLarger: 0
  depthInfo:
    dpHistAllNLarger: 559
    dpHistAltNLarger: 0
- chrom: chr1
  pos: 15974
  refAllele: C
  altAllele: G
  vep:
    - allele: G
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: DDX11L1
      gene: ENSG00000223972
      featureType: Transcript
      feature: ENST00000450305
      featureBiotype: transcribed_unprocessed_pseudogene
      dbsnpId: "1"
      distance: "2304"
      strand: "1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:37102"
    - allele: G
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: DDX11L1
      gene: ENSG00000223972
      featureType: Transcript
      feature: ENST00000456328
      featureBiotype: processed_transcript
      dbsnpId: "1"
      distance: "1565"
      strand: "1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:37102"
      canonical: true
      tsl: 1
    - allele: G
      consequence: intron_variant&non_coding_transcript_variant
      impact: MODIFIER
      symbol: WASH7P
      gene: ENSG00000227232
      featureType: Transcript
      feature: ENST00000488147
      featureBiotype: unprocessed_pseudogene
      intron: 8/10
      hgvsc: "ENST00000488147.1:n.1068-27G>C"
      dbsnpId: "1"
      strand: "-1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:38034"
      canonical: true
    - allele: G
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: MIR6859-1
      gene: ENSG00000278267
      featureType: Transcript
      feature: ENST00000619216
      featureBiotype: miRNA
      dbsnpId: "1"
      distance: "1395"
      strand: "-1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:50039"
      canonical: true
    - allele: G
      consequence: intron_variant&non_coding_transcript_variant
      impact: MODIFIER
      symbol: WASH7P
      gene: "653635"
      featureType: Transcript
      feature: NR_024540.1
      featureBiotype: transcribed_pseudogene
      intron: 8/10
      hgvsc: "NR_024540.1:n.1081-27G>C"
      dbsnpId: "1"
      strand: "-1"
      variantClass: SNV
      symbolSource: EntrezGene
      hgncId: "HGNC:38034"
      canonical: true
    - allele: G
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: DDX11L1
      gene: "100287102"
      featureType: Transcript
      feature: NR_046018.2
      featureBiotype: transcribed_pseudogene
      dbsnpId: "1"
      distance: "1565"
      strand: "1"
      variantClass: SNV
      symbolSource: EntrezGene
      hgncId: "HGNC:37102"
      canonical: true
    - allele: G
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: MIR6859-1
      gene: "102466751"
      featureType: Transcript
      feature: NR_106918.1
      featureBiotype: miRNA
      dbsnpId: "1"
      distance: "1395"
      strand: "-1"
      variantClass: SNV
      symbolSource: EntrezGene
      hgncId: "HGNC:50039"
      canonical: true
    - allele: G
      consequence: regulatory_region_variant
      impact: MODIFIER
      featureType: RegulatoryFeature
      feature: ENSR00000344266
      featureBiotype: CTCF_binding_site
      dbsnpId: "1"
      variantClass: SNV
  alleleCounts:
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          counts:
            overall:
              an: 37020
            xx:
              an: 19854
            xy:
              an: 17166
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 628
            xx:
              an: 312
            xy:
              an: 316
        - population: amr
          counts:
            overall:
              ac: 1
              an: 9600
              af: 0.000104167
            xx:
              ac: 1
              an: 4304
              af: 0.000232342
            xy:
              an: 5296
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 2252
            xx:
              an: 1230
            xy:
              an: 1022
        - population: eas
          counts:
            overall:
              an: 4642
            xx:
              an: 2056
            xy:
              an: 2586
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 5348
            xx:
              an: 1482
            xy:
              an: 3866
        - population: mid
          counts:
            overall:
              an: 238
            xx:
              an: 134
            xy:
              an: 104
        - population: nfe
          counts:
            overall:
              ac: 1
              an: 46052
              af: 0.0000217146
            xx:
              ac: 1
              an: 27020
              af: 0.0000370096
            xy:
              an: 19032
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1394
            xx:
              an: 710
            xy:
              an: 684
        - population: sas
          counts:
            overall:
              an: 3074
            xx:
              an: 762
            xy:
              an: 2312
          faf95: 0
          faf99: 0
      bySex:
        overall:
          ac: 2
          an: 110248
          af: 0.0000181409
        xx:
          ac: 2
          an: 57864
          af: 0.0000345638
        xy:
          an: 52384
      raw:
        ac: 4
        an: 134398
        nhomalt: 1
        af: 0.0000297623
      popmax: amr
      afPopmax: 0.000104167
      acPopmax: 1
      anPopmax: 9600
      nhomaltPopmax: 0
    - cohort: controls_and_biobanks
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 8096
            xx:
              an: 4198
            xy:
              an: 3898
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 30
            xx:
              an: 12
            xy:
              an: 18
        - population: amr
          counts:
            overall:
              an: 3256
            xx:
              an: 1716
            xy:
              an: 1540
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 80
            xx:
              an: 52
            xy:
              an: 28
        - population: eas
          counts:
            overall:
              an: 2232
            xx:
              an: 950
            xy:
              an: 1282
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 2622
            xx:
              an: 328
            xy:
              an: 2294
        - population: mid
          counts:
            overall:
              an: 188
            xx:
              an: 108
            xy:
              an: 80
        - population: nfe
          counts:
            overall:
              an: 4698
            xx:
              an: 2282
            xy:
              an: 2416
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 552
            xx:
              an: 290
            xy:
              an: 262
        - population: sas
          counts:
            overall:
              an: 2124
            xx:
              an: 608
            xy:
              an: 1516
          faf95: 0
          faf99: 0
      bySex:
        overall:
          an: 23878
        xx:
          an: 10544
        xy:
          an: 13334
      raw:
        an: 28664
    - cohort: non_cancer
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 36724
            xx:
              an: 19712
            xy:
              an: 17012
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 628
            xx:
              an: 312
            xy:
              an: 316
        - population: amr
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            overall:
              ac: 1
              an: 9480
              af: 0.000105485
            xx:
              ac: 1
              an: 4274
              af: 0.000233973
            xy:
              an: 5206
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 2142
            xx:
              an: 1144
            xy:
              an: 998
        - population: eas
          counts:
            overall:
              an: 4426
            xx:
              an: 1964
            xy:
              an: 2462
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 5348
            xx:
              an: 1482
            xy:
              an: 3866
        - population: mid
          counts:
            overall:
              an: 228
            xx:
              an: 130
            xy:
              an: 98
        - population: nfe
          counts:
            overall:
              ac: 1
              an: 43856
              af: 0.0000228019
            xx:
              ac: 1
              an: 26168
              af: 0.0000382146
            xy:
              an: 17688
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1346
            xx:
              an: 690
            xy:
              an: 656
        - population: sas
          counts:
            overall:
              an: 3046
            xx:
              an: 746
            xy:
              an: 2300
          faf95: 0
          faf99: 0
      bySex:
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          ac: 2
          an: 107224
          af: 0.0000186525
        xx:
          ac: 2
          an: 56622
          af: 0.000035322
        xy:
          an: 50602
      raw:
        ac: 4
        an: 130884
        nhomalt: 1
        af: 0.0000305614
    - cohort: non_neuro
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 29162
            xx:
              an: 16860
            xy:
              an: 12302
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 598
            xx:
              an: 286
            xy:
              an: 312
        - population: amr
          counts:
            overall:
              ac: 1
              an: 9352
              af: 0.000106929
            xx:
              ac: 1
              an: 4204
              af: 0.000237869
            xy:
              an: 5148
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 2206
            xx:
              an: 1210
            xy:
              an: 996
        - population: eas
          counts:
            overall:
              an: 4642
            xx:
              an: 2056
            xy:
              an: 2586
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 3356
            xx:
              an: 424
            xy:
              an: 2932
        - population: mid
          counts:
            overall:
              an: 236
            xx:
              an: 134
            xy:
              an: 102
        - population: nfe
          counts:
            overall:
              ac: 1
              an: 43536
              af: 0.0000229695
            xx:
              ac: 1
              an: 26012
              af: 0.0000384438
            xy:
              an: 17524
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1328
            xx:
              an: 680
            xy:
              an: 648
        - population: sas
          counts:
            overall:
              an: 3074
            xx:
              an: 762
            xy:
              an: 2312
          faf95: 0
          faf99: 0
      bySex:
        overall:
          ac: 2
          an: 97490
          af: 0.0000205149
        xx:
          ac: 2
          an: 52628
          af: 0.0000380026
        xy:
          an: 44862
      raw:
        ac: 4
        an: 118746
        nhomalt: 1
        af: 0.0000336853
    - cohort: non_topmed
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 21902
            xx:
              an: 10526
            xy:
              an: 11376
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 60
            xx:
              an: 38
            xy:
              an: 22
        - population: amr
          counts:
            overall:
              ac: 1
              an: 8108
              af: 0.000123335
            xx:
              ac: 1
              an: 3396
              af: 0.000294464
            xy:
              an: 4712
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 646
            xx:
              an: 178
            xy:
              an: 468
        - population: eas
          counts:
            overall:
              an: 3312
            xx:
              an: 1252
            xy:
              an: 2060
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 5278
            xx:
              an: 1438
            xy:
              an: 3840
        - population: mid
          counts:
            overall:
              an: 206
            xx:
              an: 116
            xy:
              an: 90
        - population: nfe
          counts:
            overall:
              an: 13478
            xx:
              an: 5842
            xy:
              an: 7636
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 982
            xx:
              an: 466
            xy:
              an: 516
        - population: sas
          counts:
            overall:
              an: 3060
            xx:
              an: 760
            xy:
              an: 2300
          faf95: 0
          faf99: 0
      bySex:
        overall:
          ac: 1
          an: 57032
          af: 0.000017534
        xx:
          ac: 1
          an: 24012
          af: 0.0000416458
        xy:
          an: 33020
      raw:
        ac: 3
        an: 70272
        nhomalt: 1
        af: 0.0000426913
    - cohort: non_v2
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 25546
            xx:
              an: 14138
            xy:
              an: 11408
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 628
            xx:
              an: 312
            xy:
              an: 316
        - population: amr
          counts:
            overall:
              ac: 1
              an: 8614
              af: 0.00011609
            xx:
              ac: 1
              an: 3816
              af: 0.000262055
            xy:
              an: 4798
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 2012
            xx:
              an: 1122
            xy:
              an: 890
        - population: eas
          counts:
            overall:
              an: 2514
            xx:
              an: 1186
            xy:
              an: 1328
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 3406
            xx:
              an: 616
            xy:
              an: 2790
        - population: mid
          counts:
            overall:
              an: 230
            xx:
              an: 132
            xy:
              an: 98
        - population: nfe
          counts:
            overall:
              ac: 1
              an: 35780
              af: 0.0000279486
            xx:
              ac: 1
              an: 22286
              af: 0.0000448712
            xy:
              an: 13494
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1248
            xx:
              an: 640
            xy:
              an: 608
        - population: sas
          counts:
            overall:
              an: 2348
            xx:
              an: 466
            xy:
              an: 1882
          faf95: 0
          faf99: 0
      bySex:
        overall:
          ac: 2
          an: 82326
          af: 0.0000242937
        xx:
          ac: 2
          an: 44714
          af: 0.0000447287
        xy:
          an: 37612
      raw:
        ac: 4
        an: 100384
        nhomalt: 1
        af: 0.000039847
  effectInfo:
    caddPhred: 1.385
  variantInfo:
    variantType: multi-snv
    alleleType: snv
    nAltAlleles: 2
    varDp: 2
  qualityInfo:
    asFs: 19.3275
    inbreedingCoeff: 0.499985
    asMq: 47.4448
    mqRankSum: 2.55
    asMqRankSum: 3.286
    asQd: 13.0658
    readPosRankSum: -0.645
    asReadPosRankSum: -0.645
    asSor: 0.238122
    negativeTrainSite: true
    asVqslod: -3.7033
    asCulprit: AS_MQRankSum
    asPabMax: 0.850554
    asQualApprox: 1986
    asSbTable: "66"
  ageInfo:
    ageHistHomNSmaller: 0
    ageHistHomNLarger: 0
    ageHistHetNSmaller: 0
    ageHistHetNLarger: 0
  depthInfo:
    dpHistAllNLarger: 561
    dpHistAltNLarger: 0
- chrom: chr1
  pos: 15975
  refAllele: A
  altAllele: G
  vep:
    - allele: G
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: DDX11L1
      gene: ENSG00000223972
      featureType: Transcript
      feature: ENST00000450305
      featureBiotype: transcribed_unprocessed_pseudogene
      dbsnpId: "1"
      distance: "2305"
      strand: "1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:37102"
    - allele: G
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: DDX11L1
      gene: ENSG00000223972
      featureType: Transcript
      feature: ENST00000456328
      featureBiotype: processed_transcript
      dbsnpId: "1"
      distance: "1566"
      strand: "1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:37102"
      canonical: true
      tsl: 1
    - allele: G
      consequence: intron_variant&non_coding_transcript_variant
      impact: MODIFIER
      symbol: WASH7P
      gene: ENSG00000227232
      featureType: Transcript
      feature: ENST00000488147
      featureBiotype: unprocessed_pseudogene
      intron: 8/10
      hgvsc: "ENST00000488147.1:n.1068-28T>C"
      dbsnpId: "1"
      strand: "-1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:38034"
      canonical: true
    - allele: G
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: MIR6859-1
      gene: ENSG00000278267
      featureType: Transcript
      feature: ENST00000619216
      featureBiotype: miRNA
      dbsnpId: "1"
      distance: "1394"
      strand: "-1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:50039"
      canonical: true
    - allele: G
      consequence: intron_variant&non_coding_transcript_variant
      impact: MODIFIER
      symbol: WASH7P
      gene: "653635"
      featureType: Transcript
      feature: NR_024540.1
      featureBiotype: transcribed_pseudogene
      intron: 8/10
      hgvsc: "NR_024540.1:n.1081-28T>C"
      dbsnpId: "1"
      strand: "-1"
      variantClass: SNV
      symbolSource: EntrezGene
      hgncId: "HGNC:38034"
      canonical: true
    - allele: G
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: DDX11L1
      gene: "100287102"
      featureType: Transcript
      feature: NR_046018.2
      featureBiotype: transcribed_pseudogene
      dbsnpId: "1"
      distance: "1566"
      strand: "1"
      variantClass: SNV
      symbolSource: EntrezGene
      hgncId: "HGNC:37102"
      canonical: true
    - allele: G
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: MIR6859-1
      gene: "102466751"
      featureType: Transcript
      feature: NR_106918.1
      featureBiotype: miRNA
      dbsnpId: "1"
      distance: "1394"
      strand: "-1"
      variantClass: SNV
      symbolSource: EntrezGene
      hgncId: "HGNC:50039"
      canonical: true
    - allele: G
      consequence: regulatory_region_variant
      impact: MODIFIER
      featureType: RegulatoryFeature
      feature: ENSR00000344266
      featureBiotype: CTCF_binding_site
      dbsnpId: "1"
      variantClass: SNV
  alleleCounts:
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        - population: afr
          counts:
            overall:
              an: 37052
            xx:
              an: 19886
            xy:
              an: 17166
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 630
            xx:
              an: 314
            xy:
              an: 316
        - population: amr
          counts:
            overall:
              an: 9628
            xx:
              an: 4324
            xy:
              an: 5304
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 2274
            xx:
              an: 1240
            xy:
              an: 1034
        - population: eas
          counts:
            overall:
              an: 4632
            xx:
              an: 2052
            xy:
              an: 2580
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 5370
            xx:
              an: 1478
            xy:
              an: 3892
        - population: mid
          counts:
            overall:
              an: 232
            xx:
              an: 134
            xy:
              an: 98
        - population: nfe
          counts:
            overall:
              an: 46096
            xx:
              an: 27066
            xy:
              an: 19030
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1398
            xx:
              an: 708
            xy:
              an: 690
        - population: sas
          counts:
            overall:
              an: 3106
            xx:
              an: 766
            xy:
              an: 2340
          faf95: 0
          faf99: 0
      bySex:
        overall:
          an: 110418
        xx:
          an: 57968
        xy:
          an: 52450
      raw:
        ac: 2
        an: 134428
        af: 0.0000148779
    - cohort: controls_and_biobanks
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 8082
            xx:
              an: 4190
            xy:
              an: 3892
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 30
            xx:
              an: 12
            xy:
              an: 18
        - population: amr
          counts:
            overall:
              an: 3264
            xx:
              an: 1732
            xy:
              an: 1532
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 84
            xx:
              an: 54
            xy:
              an: 30
        - population: eas
          counts:
            overall:
              an: 2218
            xx:
              an: 944
            xy:
              an: 1274
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 2652
            xx:
              an: 332
            xy:
              an: 2320
        - population: mid
          counts:
            overall:
              an: 186
            xx:
              an: 108
            xy:
              an: 78
        - population: nfe
          counts:
            overall:
              an: 4692
            xx:
              an: 2278
            xy:
              an: 2414
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 554
            xx:
              an: 286
            xy:
              an: 268
        - population: sas
          counts:
            overall:
              an: 2134
            xx:
              an: 608
            xy:
              an: 1526
          faf95: 0
          faf99: 0
      bySex:
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          an: 23896
        xx:
          an: 10544
        xy:
          an: 13352
      raw:
        ac: 1
        an: 28646
        af: 0.0000349089
    - cohort: non_cancer
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 36756
            xx:
              an: 19744
            xy:
              an: 17012
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 630
            xx:
              an: 314
            xy:
              an: 316
        - population: amr
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            overall:
              an: 9512
            xx:
              an: 4294
            xy:
              an: 5218
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 2162
            xx:
              an: 1154
            xy:
              an: 1008
        - population: eas
          counts:
            overall:
              an: 4422
            xx:
              an: 1966
            xy:
              an: 2456
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 5370
            xx:
              an: 1478
            xy:
              an: 3892
        - population: mid
          counts:
            overall:
              an: 224
            xx:
              an: 130
            xy:
              an: 94
        - population: nfe
          counts:
            overall:
              an: 43918
            xx:
              an: 26222
            xy:
              an: 17696
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1352
            xx:
              an: 690
            xy:
              an: 662
        - population: sas
          counts:
            overall:
              an: 3078
            xx:
              an: 750
            xy:
              an: 2328
          faf95: 0
          faf99: 0
      bySex:
        overall:
          an: 107424
        xx:
          an: 56742
        xy:
          an: 50682
      raw:
        ac: 2
        an: 130948
        af: 0.0000152732
    - cohort: non_neuro
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 29182
            xx:
              an: 16882
            xy:
              an: 12300
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 600
            xx:
              an: 288
            xy:
              an: 312
        - population: amr
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            overall:
              an: 9380
            xx:
              an: 4222
            xy:
              an: 5158
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 2224
            xx:
              an: 1218
            xy:
              an: 1006
        - population: eas
          counts:
            overall:
              an: 4632
            xx:
              an: 2052
            xy:
              an: 2580
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 3388
            xx:
              an: 426
            xy:
              an: 2962
        - population: mid
          counts:
            overall:
              an: 230
            xx:
              an: 134
            xy:
              an: 96
        - population: nfe
          counts:
            overall:
              an: 43582
            xx:
              an: 26048
            xy:
              an: 17534
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1332
            xx:
              an: 678
            xy:
              an: 654
        - population: sas
          counts:
            overall:
              an: 3106
            xx:
              an: 766
            xy:
              an: 2340
          faf95: 0
          faf99: 0
      bySex:
        overall:
          an: 97656
        xx:
          an: 52714
        xy:
          an: 44942
      raw:
        ac: 2
        an: 118802
        af: 0.0000168347
    - cohort: non_topmed
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 21918
            xx:
              an: 10540
            xy:
              an: 11378
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 60
            xx:
              an: 38
            xy:
              an: 22
        - population: amr
          counts:
            overall:
              an: 8132
            xx:
              an: 3412
            xy:
              an: 4720
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 652
            xx:
              an: 178
            xy:
              an: 474
        - population: eas
          counts:
            overall:
              an: 3298
            xx:
              an: 1244
            xy:
              an: 2054
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 5302
            xx:
              an: 1436
            xy:
              an: 3866
        - population: mid
          counts:
            overall:
              an: 202
            xx:
              an: 116
            xy:
              an: 86
        - population: nfe
          counts:
            overall:
              an: 13458
            xx:
              an: 5846
            xy:
              an: 7612
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 984
            xx:
              an: 462
            xy:
              an: 522
        - population: sas
          counts:
            overall:
              an: 3092
            xx:
              an: 764
            xy:
              an: 2328
          faf95: 0
          faf99: 0
      bySex:
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          an: 57098
        xx:
          an: 24036
        xy:
          an: 33062
      raw:
        ac: 2
        an: 70230
        af: 0.0000284779
    - cohort: non_v2
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 25586
            xx:
              an: 14168
            xy:
              an: 11418
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 630
            xx:
              an: 314
            xy:
              an: 316
        - population: amr
          counts:
            overall:
              an: 8634
            xx:
              an: 3822
            xy:
              an: 4812
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 2036
            xx:
              an: 1132
            xy:
              an: 904
        - population: eas
          counts:
            overall:
              an: 2518
            xx:
              an: 1188
            xy:
              an: 1330
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 3416
            xx:
              an: 606
            xy:
              an: 2810
        - population: mid
          counts:
            overall:
              an: 224
            xx:
              an: 132
            xy:
              an: 92
        - population: nfe
          counts:
            overall:
              an: 35826
            xx:
              an: 22326
            xy:
              an: 13500
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1252
            xx:
              an: 640
            xy:
              an: 612
        - population: sas
          counts:
            overall:
              an: 2380
            xx:
              an: 470
            xy:
              an: 1910
          faf95: 0
          faf99: 0
      bySex:
        overall:
          an: 82502
        xx:
          an: 44798
        xy:
          an: 37704
      raw:
        ac: 2
        an: 100460
        af: 0.0000199084
  effectInfo:
    caddPhred: 8.532
  variantInfo:
    variantType: snv
    alleleType: snv
    nAltAlleles: 1
    varDp: 1
  qualityInfo:
    asFs: 1.29277
    inbreedingCoeff: -0.0000149012
    asMq: 44.7114
    mqRankSum: 1.611
    asMqRankSum: 1.611
    asQd: 5.3617
    readPosRankSum: -1.396
    asReadPosRankSum: -1.396
    asSor: 0.963111
    negativeTrainSite: true
    asVqslod: -2.989
    asCulprit: AS_QD
    asPabMax: 0.404873
    asQualApprox: 252
    asSbTable: "21"
  ageInfo:
    ageHistHomNSmaller: 0
    ageHistHomNLarger: 0
    ageHistHetNSmaller: 0
    ageHistHetNLarger: 0
  depthInfo:
    dpHistAllNLarger: 561
    dpHistAltNLarger: 0
- chrom: chr1
  pos: 15977
  refAllele: G
  altAllele: A
  vep:
    - allele: A
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: DDX11L1
      gene: ENSG00000223972
      featureType: Transcript
      feature: ENST00000450305
      featureBiotype: transcribed_unprocessed_pseudogene
      dbsnpId: "1"
      distance: "2307"
      strand: "1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:37102"
    - allele: A
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: DDX11L1
      gene: ENSG00000223972
      featureType: Transcript
      feature: ENST00000456328
      featureBiotype: processed_transcript
      dbsnpId: "1"
      distance: "1568"
      strand: "1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:37102"
      canonical: true
      tsl: 1
    - allele: A
      consequence: intron_variant&non_coding_transcript_variant
      impact: MODIFIER
      symbol: WASH7P
      gene: ENSG00000227232
      featureType: Transcript
      feature: ENST00000488147
      featureBiotype: unprocessed_pseudogene
      intron: 8/10
      hgvsc: "ENST00000488147.1:n.1068-30C>T"
      dbsnpId: "1"
      strand: "-1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:38034"
      canonical: true
    - allele: A
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: MIR6859-1
      gene: ENSG00000278267
      featureType: Transcript
      feature: ENST00000619216
      featureBiotype: miRNA
      dbsnpId: "1"
      distance: "1392"
      strand: "-1"
      variantClass: SNV
      symbolSource: HGNC
      hgncId: "HGNC:50039"
      canonical: true
    - allele: A
      consequence: intron_variant&non_coding_transcript_variant
      impact: MODIFIER
      symbol: WASH7P
      gene: "653635"
      featureType: Transcript
      feature: NR_024540.1
      featureBiotype: transcribed_pseudogene
      intron: 8/10
      hgvsc: "NR_024540.1:n.1081-30C>T"
      dbsnpId: "1"
      strand: "-1"
      variantClass: SNV
      symbolSource: EntrezGene
      hgncId: "HGNC:38034"
      canonical: true
    - allele: A
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: DDX11L1
      gene: "100287102"
      featureType: Transcript
      feature: NR_046018.2
      featureBiotype: transcribed_pseudogene
      dbsnpId: "1"
      distance: "1568"
      strand: "1"
      variantClass: SNV
      symbolSource: EntrezGene
      hgncId: "HGNC:37102"
      canonical: true
    - allele: A
      consequence: downstream_gene_variant
      impact: MODIFIER
      symbol: MIR6859-1
      gene: "102466751"
      featureType: Transcript
      feature: NR_106918.1
      featureBiotype: miRNA
      dbsnpId: "1"
      distance: "1392"
      strand: "-1"
      variantClass: SNV
      symbolSource: EntrezGene
      hgncId: "HGNC:50039"
      canonical: true
    - allele: A
      consequence: regulatory_region_variant
      impact: MODIFIER
      featureType: RegulatoryFeature
      feature: ENSR00000344266
      featureBiotype: CTCF_binding_site
      dbsnpId: "1"
      variantClass: SNV
  alleleCounts:
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        - population: afr
          counts:
            overall:
              an: 37134
            xx:
              an: 19924
            xy:
              an: 17210
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 634
            xx:
              an: 316
            xy:
              an: 318
        - population: amr
          counts:
            overall:
              an: 9746
            xx:
              an: 4366
            xy:
              an: 5380
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 2302
            xx:
              an: 1258
            xy:
              an: 1044
        - population: eas
          counts:
            overall:
              an: 4670
            xx:
              an: 2072
            xy:
              an: 2598
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 5472
            xx:
              an: 1494
            xy:
              an: 3978
        - population: mid
          counts:
            overall:
              an: 240
            xx:
              an: 136
            xy:
              an: 104
        - population: nfe
          counts:
            overall:
              an: 46698
            xx:
              an: 27388
            xy:
              an: 19310
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1404
            xx:
              an: 710
            xy:
              an: 694
        - population: sas
          counts:
            overall:
              an: 3138
            xx:
              an: 766
            xy:
              an: 2372
          faf95: 0
          faf99: 0
      bySex:
        overall:
          an: 111438
        xx:
          an: 58430
        xy:
          an: 53008
      raw:
        ac: 1
        an: 134888
        af: 0.00000741356
    - cohort: controls_and_biobanks
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 8112
            xx:
              an: 4210
            xy:
              an: 3902
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 30
            xx:
              an: 12
            xy:
              an: 18
        - population: amr
          counts:
            overall:
              an: 3296
            xx:
              an: 1750
            xy:
              an: 1546
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 88
            xx:
              an: 56
            xy:
              an: 32
        - population: eas
          counts:
            overall:
              an: 2238
            xx:
              an: 954
            xy:
              an: 1284
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 2706
            xx:
              an: 326
            xy:
              an: 2380
        - population: mid
          counts:
            overall:
              an: 190
            xx:
              an: 110
            xy:
              an: 80
        - population: nfe
          counts:
            overall:
              an: 4744
            xx:
              an: 2312
            xy:
              an: 2432
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 558
            xx:
              an: 288
            xy:
              an: 270
        - population: sas
          counts:
            overall:
              an: 2158
            xx:
              an: 610
            xy:
              an: 1548
          faf95: 0
          faf99: 0
      bySex:
        overall:
          an: 24120
        xx:
          an: 10628
        xy:
          an: 13492
      raw:
        an: 28832
    - cohort: non_cancer
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 36838
            xx:
              an: 19782
            xy:
              an: 17056
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 634
            xx:
              an: 316
            xy:
              an: 318
        - population: amr
          counts:
            overall:
              an: 9628
            xx:
              an: 4336
            xy:
              an: 5292
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 2188
            xx:
              an: 1170
            xy:
              an: 1018
        - population: eas
          counts:
            overall:
              an: 4456
            xx:
              an: 1982
            xy:
              an: 2474
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 5472
            xx:
              an: 1494
            xy:
              an: 3978
        - population: mid
          counts:
            overall:
              an: 230
            xx:
              an: 132
            xy:
              an: 98
        - population: nfe
          counts:
            overall:
              an: 44500
            xx:
              an: 26552
            xy:
              an: 17948
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1356
            xx:
              an: 692
            xy:
              an: 664
        - population: sas
          counts:
            overall:
              an: 3110
            xx:
              an: 750
            xy:
              an: 2360
          faf95: 0
          faf99: 0
      bySex:
        overall:
          an: 108412
        xx:
          an: 57206
        xy:
          an: 51206
      raw:
        ac: 1
        an: 131384
        af: 0.00000761128
    - cohort: non_neuro
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 29240
            xx:
              an: 16914
            xy:
              an: 12326
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 604
            xx:
              an: 290
            xy:
              an: 314
        - population: amr
          counts:
            overall:
              an: 9492
            xx:
              an: 4262
            xy:
              an: 5230
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 2252
            xx:
              an: 1236
            xy:
              an: 1016
        - population: eas
          counts:
            overall:
              an: 4670
            xx:
              an: 2072
            xy:
              an: 2598
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 3450
            xx:
              an: 420
            xy:
              an: 3030
        - population: mid
          counts:
            overall:
              an: 238
            xx:
              an: 136
            xy:
              an: 102
        - population: nfe
          counts:
            overall:
              an: 44134
            xx:
              an: 26354
            xy:
              an: 17780
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1340
            xx:
              an: 682
            xy:
              an: 658
        - population: sas
          counts:
            overall:
              an: 3138
            xx:
              an: 766
            xy:
              an: 2372
          faf95: 0
          faf99: 0
      bySex:
        overall:
          an: 98558
        xx:
          an: 53132
        xy:
          an: 45426
      raw:
        an: 119214
    - cohort: non_topmed
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 21974
            xx:
              an: 10564
            xy:
              an: 11410
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 60
            xx:
              an: 38
            xy:
              an: 22
        - population: amr
          counts:
            overall:
              an: 8228
            xx:
              an: 3444
            xy:
              an: 4784
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 658
            xx:
              an: 184
            xy:
              an: 474
        - population: eas
          counts:
            overall:
              an: 3330
            xx:
              an: 1258
            xy:
              an: 2072
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 5402
            xx:
              an: 1450
            xy:
              an: 3952
        - population: mid
          counts:
            overall:
              an: 208
            xx:
              an: 118
            xy:
              an: 90
        - population: nfe
          counts:
            overall:
              an: 13668
            xx:
              an: 5924
            xy:
              an: 7744
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 992
            xx:
              an: 466
            xy:
              an: 526
        - population: sas
          counts:
            overall:
              an: 3124
            xx:
              an: 764
            xy:
              an: 2360
          faf95: 0
          faf99: 0
      bySex:
        overall:
          an: 57644
        xx:
          an: 24210
        xy:
          an: 33434
      raw:
        ac: 1
        an: 70540
        af: 0.0000141764
    - cohort: non_v2
      byPopulation:
        - population: afr
          counts:
            overall:
              an: 25636
            xx:
              an: 14188
            xy:
              an: 11448
          faf95: 0
          faf99: 0
        - population: ami
          counts:
            overall:
              an: 634
            xx:
              an: 316
            xy:
              an: 318
        - population: amr
          counts:
            overall:
              an: 8738
            xx:
              an: 3858
            xy:
              an: 4880
          faf95: 0
          faf99: 0
        - population: asj
          counts:
            overall:
              an: 2056
            xx:
              an: 1146
            xy:
              an: 910
        - population: eas
          counts:
            overall:
              an: 2532
            xx:
              an: 1198
            xy:
              an: 1334
          faf95: 0
          faf99: 0
        - population: fin
          counts:
            overall:
              an: 3498
            xx:
              an: 616
            xy:
              an: 2882
        - population: mid
          counts:
            overall:
              an: 232
            xx:
              an: 134
            xy:
              an: 98
        - population: nfe
          counts:
            overall:
              an: 36264
            xx:
              an: 22592
            xy:
              an: 13672
          faf95: 0
          faf99: 0
        - population: oth
          counts:
            overall:
              an: 1256
            xx:
              an: 640
            xy:
              an: 616
        - population: sas
          counts:
            overall:
              an: 2404
            xx:
              an: 468
            xy:
              an: 1936
          faf95: 0
          faf99: 0
      bySex:
        overall:
          an: 83250
        xx:
          an: 45156
        xy:
          an: 38094
      raw:
        an: 100826
  effectInfo:
    caddPhred: 4.644
  variantInfo:
    variantType: multi-snv
    alleleType: snv
    nAltAlleles: 2
    varDp: 2
  qualityInfo:
    asFs: 1.34551
    inbreedingCoeff: -0.00000739098
    asMq: 46.237
    mqRankSum: -0.067
    asMqRankSum: 3.027
    asQd: 3.17544
    readPosRankSum: -1.001
    asReadPosRankSum: -1.001
    asSor: 0.367725
    negativeTrainSite: true
    asVqslod: -2.5822
    asCulprit: AS_QD
    asPabMax: 0.6875
    asQualApprox: 181
    asSbTable: "34"
  ageInfo:
    ageHistHomNSmaller: 0
    ageHistHomNLarger: 0
    ageHistHetNSmaller: 0
    ageHistHetNLarger: 0
  depthInfo:
    dpHistAllNLarger: 561
    dpHistAltNLarger: 0

