>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
----------------------------------------MNG----------------T
E--G--DNFYVP----FSNKTGLARSPYEYPQY-------YLAEPWK---------YSAL
AAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-FTVTMYTSM
N-GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGN-FRFGNTHAIM
GVAFTWIMALAC-AAPPLVG-W-----SRYIPEGMQCSCGPDYYTLNPNFNNESYVVYMF
VVHFLVPFVIIFFCYGRLLCTV----KEAAAAQQ--------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------ESASTQK------AEKEVTRMVVLMVIGFLVCWVPYASVAFYIFT-H
QGS--DFGATFMTLPAFFAKSSALYNPVIYILMNKQFRNCMITTLCC--------GKNPL
GDDE--SGASTSKTEVSSVS-TSPVSPA--------------------------------
---------------------------------------------------------
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
----------------------------------------MNG----------------T
E--G--PNFYVP----FSNITGVVRSPFEQPQY-------YLAEPWQ---------FSML
AAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTTLYTSL
H-GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSN-FRFGENHAIM
GVAFTWVMALAC-AAPPLVG-W-----SRYIPEGMQCSCGIDYYTLKPEVNNESFVIYMF
VVHFTIPMIVIFFCYGQLVFTV----KEAAAQQQ--------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------ESATTQK------AEKEVTRMVIIMVIFFLICWLPYASVAMYIFT-H
QGS--NFGPIFMTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSLCC--------GKNPL
GDDE--ASATASKTE------TSQVAPA--------------------------------
---------------------------------------------------------
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
----------------------------------------MNG----------------T
E--G--INFYVP----MSNKTGVVRSPFEYPQY-------YLAEPWK---------YRLV
CCYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-FTVTFYTAW
N-GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGN-FRFSATHAMM
GIAFTWVMAFSC-AAPPLFG-W-----SRYMPEGMQCSCGPDYYTHNPDYHNESYVLYMF
VIHFIIPVVVIFFSYGRLICKV----REAAAQQQ--------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------ESATTQK------AEKEVTRMVILMVLGFMLAWTPYAVVAFWIFT-N
KGA--DFTATLMAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTICC--------GKNPF
GDEDVSSTVSQSKTEVSSVS-SSQVSPA--------------------------------
---------------------------------------------------------
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
----------------------------------------MNG----------------T
E--G--KNFYVP----MSNRTGLVRSPFEYPQY-------YLAEPWQ---------FKIL
ALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-FTVTFYTAI
N-GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSSSHAFA
GIAFTWVMALAC-AAPPLFG-W-----SRYIPEGMQCSCGPDYYTLNPDYNNESYVIYMF
VCHFILPVAVIFFTYGRLVCTV----KAAAAQQQ--------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------DSASTQK------AEREVTKMVILMVFGFLIAWTPYATVAAWIFF-N
KGA--DFSAKFMAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTIFC--------GKNPL
GDDE-SSTVSTSKTEVSS------VSPA--------------------------------
---------------------------------------------------------
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
----------------------------------------MNG----------------T
E--G--NNFYVP----LSNRTGLVRSPFEYPQY-------YLAEPWQ---------FKLL
AVYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-FTVTFYTAI
N-GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSSTHASA
GIAFTWVMAMAC-AAPPLVG-W-----SRYIPEGIQCSCGPDYYTLNPEYNNESYVLYMF
ICHFILPVTIIFFTYGRLVCTV----KAAAAQQQ--------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------DSASTQK------AEREVTKMVILMVLGFLVAWTPYATVAAWIFF-N
KGA--AFSAQFMAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTLFC--------GKNPL
GDEE-SSTVSTSKTEVSS------VSPA--------------------------------
---------------------------------------------------------
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
----------------------------------------MKQ----------------V
PEFH--EDFYIPIPLDINNLS--AYSPFLVPQD-------HLGNQGI---------FMAM
SVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-SPLSFYSFF
N-RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGN-FTFKTPHAIA
GCILPWISALAA-SLPPLFG-W-----SRYIPEGLQCSCGPDWYTTNNKYNNESYVMFLF
CFCFAVPFGTIVFCYGQLLITL----KLAAKAQA--------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------DSASTQK------AEREVTKMVVVMVLGFLVCWAPYASFSLWIVS-H
RGE--EFDLRMATIPSCLSKASTVYNPVIYVLMNKQFRSCMM-KMVC--------GKN-I
EEDE--ASTSSQVTQVSS------VAPEK-------------------------------
---------------------------------------------------------
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
----------------------------------------MRK----------------M
S--E--EEFYL-----FKNIS--SVGPWDGPQY-------HIAPVWA---------FYLQ
AAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-VFPVFVASC
N-GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGN-FRFSSKHALT
VVLATWTIGIGV-SIPPFFG-W-----SRFIPEGLQCSCGPDWYTVGTKYRSESYTWFLF
IFCFIVPLSLICFSYTQLLRAL----KAVAAQQQ--------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------ESATTQK------AEREVSRMVVVMVGSFCVCYVPYAAFAMYMVN-N
RNH--GLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIM-KMVC--------GKA-M
TDES--DTCSSQKTEVSTVS-STQVGPN--------------------------------
---------------------------------------------------------
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------DLAETVIA-STISIVNQV
S-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDAKLAIV
GIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLM
VTCCITPLSIIVLCYLQVWLAI----RAVAKQQK--------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------ESESTQK------AEKEVTRMVVVMVLAFC-----------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
----------------------------------------MAQQWSLQRLAGRHPQDSYE
DSTQ--SSIFT-----YTNSNS-TRGPFEGPNY-------HIAPRWV---------YHLT
SVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISVVNQV
Y-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGN-VRFDAKLAIV
GIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLM
VTCCITPLSIIVLCYLQVWLAI----RAVAKQQK--------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------ESESTQK------AEKEVTRMVVVMVLAFCFCWGPYAFFACFAAA-N
PGY--PFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCIL-QLF---------GKK-V
DDGS--ELSSASKTEVSSV---SSVSPA--------------------------------
---------------------------------------------------------
>    10== Z68193   1 human Red Opsin <>[]
----------------------------------------MAQQWSLQRLAGRHPQDSYE
DSTQ--SSIFT-----YTNSNS-TRGPFEGPNY-------HIAPRWV---------YHLT
SVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISIVNQV
S-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDAKLAIV
GIAFSWIWSAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLM
VTCCIIPLAIIMLCYLQVWLAI----RAVAKQQK--------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------ESESTQK------AEKEVTRMVVVMIFAYCVCWGPYTFFACFAAA-N
PGY--AFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCIL-QLF---------GKK-V
DDGS--ELSSASKTEVSSV---SSVSPA--------------------------------
---------------------------------------------------------
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
----------------------------------------MTEAWNVAVFAARRSRDD-D
DTTR--GSVFT-----YTNTNN-TRGPFEGPNY-------HIAPRWV---------YNLV
SFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-STISVFNQI
F-GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGN-IKFDSKLAII
GIVFSWVWAWGW-SAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSVELGCQSFMLTLM
ITCCFLPLFIIIVCYLQVWMAI----RAVAAQQK--------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------ESESTQK------AEREVSRMVVVMIVAFCICWGPYASFVSFAAA-N
PGY--AFHPLAAALPAYFAKSATIYNPVIYVFMNRQFRNCIM-QLF---------GKK-V
DDGS--EASTTSRTEVSSVS-NSSVAPA--------------------------------
---------------------------------------------------------
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
----------------------------------------MAA-WEAAFAARRRHEE--E
DTTR--DSVFT-----YTNSNN-TRGPFEGPNY-------HIAPRWV---------YNLT
SVWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVIA-STISVINQI
S-GYFI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGN-IKFDGKLAVA
GILFSWLWSCAW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSDPGVQSYMVVLM
VTCCFFPLAIIILCYLQVWLAI----RAVAAQQK--------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------ESESTQK------AEKEVSRMVVVMIVAYCFCWGPYTFFACFAAA-N
PGY--AFHPLAAALPAYFAKSATIYNPIIYVFMNRQFRNCIL-QLF---------GKK-V
DDGS--EVST-SRTEVSSVS-NSSVSPA--------------------------------
---------------------------------------------------------
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
----------------------------------------MS-----------------S
NSSQ--AP-----------PNG-TPGPFDGPQW------PYQAPQST---------YVGV
AVLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-SSVSLSNNI
N-GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGD-FQFQRRHAVS
GCAFTWGWALLW-SAPPLLG-W-----SSYVPEGLRTSCGPNWYTGGSNN--NSYILSLF
VTCFVLPLSLILFSYTNLLLTL----RAAAAQQK--------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------EADTTQR------AEREVTRMVIVMVMAFLLCWLPYSTFALVVAT-H
KGI--IIQPVLASLPSYFSKTATVYNPIIYVFMNKQFQSCLL-EMLCCGY----QPQR-T
GKAS--PGTPGPHADVTAAGLRNKVMPAHPV-----------------------------
---------------------------------------------------------
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
----------MESGNVSS------------SLFGNVST-ALRP----------------E
ARLS--A----------ETRLLGWNVPPEELR--------HIPEHWLTYPEPPESMNYLL
GTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK--TPIFIYNSF
H-QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--KMTHGKAIA
MIIFIYMYATPW-VVACYTETW-----GRFVPEGYLTSCTFDYLT--DNFDTRLFVACIF
FFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKK-------------------------
--------------------------------------------------MN--------
--VESL------------------------------------------------------
----------RSNVDKNKET------AEIRIAKAAITICFLFFCSWTPYGVMSLIGAF-G
DKT--LLTPGATMIPACACKMVACIDPFVYAISHPRYRMELQKRCPWLAL---------N
EKAP--ESSAVASTSTTQEP--QQTTAA--------------------------------
---------------------------------------------------------
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
----------MEYHNVSS------------VL-GNVSS-VLRP----------------D
ARLS--A----------ESRLLGWNVPPDELR--------HIPEHWLIYPEPPESMNYLL
GTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMIK--TPIFIYNSF
H-QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--KMTHGKAIA
MIIFIYLYATPW-VVACYTESW-----GRFVPEGYLTSCTFDYLT--DNFDTRLFVACIF
FFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKK-------------------------
--------------------------------------------------MN--------
--VDSL------------------------------------------------------
----------RSNVDKSKEA------AEIRIAKAAITICFLFFASWTPYGVMSLIGAF-G
DKT--LLTPGATMIPACTCKMVACIDPFVYAISHPRYRMELQKRCPWLAI---------S
EKAP--ESRAAISTSTTQEQ--QQTTAA--------------------------------
---------------------------------------------------------
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
----------ME------------------PL-CNASEPPLRP----------------E
AR-S--SG---N----GDLQFLGWNVPPDQIQ--------YIPEHWLTQLEPPASMHYML
GVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIF--NSF
H-RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVI
MNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFDTRLFVGTIF
FFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKK-------------------------
--------------------------------------------------MN--------
--VESL------------------------------------------------------
----------RSNVDKSKET------AEIRIAKAAITICFLFFVSWTPYGVMSLIGAF-G
DKS--LLTQGATMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWLGV---------N
EKSG--EISSAQST-TTQEQ--QQTTAA--------------------------------
---------------------------------------------------------
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
----------MD------------------AL-CNASEPPLRP----------------E
ARMS--SG---S----DELQFLGWNVPPDQIQ--------YIPEHWLTQLEPPASMHYML
GVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIFIYNSF
H-RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVI
MNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFDTRLFVGTIF
LFSFVVPTLMILYYYSQIVGHVFNHEKALREQAKK-------------------------
--------------------------------------------------MN--------
--VESL------------------------------------------------------
----------RSNVDKSKET------AEIRIAKAAITICFLFFVSWTPYGVMSLIGAF-G
DKS--LLTPGATMIPACTCKLVACIEPFVYAISHPRYRMELQKRCPWLGV---------N
EKSG--EASSAQST-TTQEQ-TQQTSAA--------------------------------
---------------------------------------------------------
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
--------------------------------MTNATGPQMAY----------------Y
GAAS--MD-FGY----PEGVSIVDFVRPEIKP--------YVHQHWYNYPPVNPMWHYLL
GVIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTTN-VPFFTYNCF
SGGVWM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNG-PKLTTGKAVV
FALISWVIAIGC-ALPPFFG-W-----GNYILEGILDSCSYDYLT--QDFNTFSYNIFIF
VFDYFLPAAIIVFSYVFIVKAIFAHEAAMRAQAKK-------------------------
--------------------------------------------------MN--------
--VSTL------------------------------------------------------
----------RS-NEADAQR------AEIRIAKTALVNVSLWFICWTPYALISLKGVM-G
DTS--GITPLVSTLPALLAKSCSCYNPFVYAISHPKYRLAITQHLPWFCV------HE-T
ETKS--NDDSQSNSTVAQDK-A--------------------------------------
---------------------------------------------------------
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
--------------------------------MANVTGPQMAF----------------Y
GSGA--AT-FGY----PEGMTVADFVPDRVKH--------MVLDHWYNYPPVNPMWHYLL
GVVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-FPPFCYNCF
SGGRWM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNG-PKLTQGKATF
MCGLAWVISVGW-SLPPFFG-W-----GSYTLEGILDSCSYDYFT--RDMNTITYNICIF
IFDFFLPASVIVFSYVFIVKAIFAHEAAMRAQAKK-------------------------
--------------------------------------------------MN--------
--VTNL------------------------------------------------------
----------RS-NEAETQR------AEIRIAKTALVNVSLWFICWTPYAAITIQGLL-G
NAE--GITPLLTTLPALLAKSCSCYNPFVYAISHPKFRLAITQHLPWFCV------HE-K
DPND--VEENQSSNTQTQEK-S--------------------------------------
---------------------------------------------------------
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
----------ME----SF------------AVAAAQLGPHFAP----------------L
S-----------------NGSVVDKVTPDMAH--------LISPYWNQFPAMDPIWAKIL
TAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLY
F-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALG
KM---------------------------YVPEGNLTSCGIDYLE--RDWNPRSYLIFYS
IFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKK-------------------------
--------------------------------------------------MN--------
--VKSL------------------------------------------------------
----------RS-SEDAEKS------AEGKLAKVALVTITLWFMAWTPYLVINCMGLF-K
F-E--GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------GK-V
DDGK--SSDAQSQA-TASEA-ESKA-----------------------------------
---------------------------------------------------------
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
----------ME----SF------------AVAAAQLGPHFAP----------------L
S-----------------NGSVVDKVTPDMAH--------LISPYWNQFPAMDPIWAKIL
TAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLY
F-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALG
KIAYIWFMSSIW-CLAPAFG-W-----SRYVPEGNLTSCGIDYLE--RDWNPRSYLIFYS
IFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKK-------------------------
--------------------------------------------------MN--------
--VKSL------------------------------------------------------
----------RS-SEDAEKS------AEGKLAKVALVTITLWFMAWTPYLVINCMGLF-K
F-E--GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------GK-V
DDGK--SSDAQSQA-TASEA-ESKA-----------------------------------
---------------------------------------------------------
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
----------MD----SF------------AAVATQLGPQFAA----------------P
S-----------------NGSVVDKVTPDMAH--------LISPYWDQFPAMDPIWAKIL
TAYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLY
F-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALG
KIAYIWFMSTIWCCLAPVFG-W-----SRYVPEGNLTSCGIDYLE--RDWNPRSYLIFYS
IFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKK-------------------------
--------------------------------------------------MN--------
--VKSL------------------------------------------------------
----------RS-SEDADKS------AEGKLAKVALVTISLWFMAWTPYLVINCMGLF-K
F-E--GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------GK-V
DDGK--SSEAQSQA-TTSEA-ESKA-----------------------------------
---------------------------------------------------------
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
-----MERSHLP----ET------------PFDLAHSGPRFQA----------------Q
SSG---------------NGSVLDNVLPDMAH--------LVNPYWSRFAPMDPMMSKIL
GLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFY
Y-ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIKTSIM
KILFIWMMAVFW-TVMPLIG-W-----SAYVPEGNLTACSIDYMT--RMWNPRSYLITYS
LFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKK-------------------------
--------------------------------------------------MN--------
--VKSL------------------------------------------------------
----------RS-SEDCDKS------AEGKLAKVALTTISLWFMAWTPYLVICYFGLF-K
I-D--GLTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMCVF------GN-T
DEPK--PDAPASDTETTSEA-DSKA-----------------------------------
---------------------------------------------------------
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
-----MERSLLP----EP------------PLAMALLGPRFEA----------------Q
TGG---------------NRSVLDNVLPDMAP--------LVNPHWSRFAPMDPTMSKIL
GLFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFY
Y-ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIKTSIM
KIAFIWMMAVFW-TIMPLIG-W-----SSYVPEGNLTACSIDYMT--RQWNPRSYLITYS
LFVYYTPLFMICYSYWFIIATVAAHEKAMRDQAKK-------------------------
--------------------------------------------------MN--------
--VKSL------------------------------------------------------
----------RS-SEDCDKS------AENKLAKVALTTISLWFMAWTPYLIICYFGLF-K
I-D--GLTPLTTIWGATFAKTSAVYNPIVYGISHPNDRLVLKEKCPMCVC------GT-T
DEPK--PDAPPSDTETTSEA-ESKD-----------------------------------
---------------------------------------------------------
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
--------------------------------MIAVSGPSYEA----------------F
SYGG--QARF-------NNQTVVDKVPPDMLH--------LIDANWYQYPPLNPMWHGIL
GFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-SPPMVINCY
Y-ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSG-KPLSINGALI
RIIAIWLFSLGW-TIAPMFG-W-----NRYVPEGNMTACGTDYFN--RGLLSASYLVCYG
IWVYFVPLFLIIYSYWFIIQAVAAHEKNMREQAKK-------------------------
--------------------------------------------------MN--------
--VASL------------------------------------------------------
----------RS-SENQNTS------AECKLAKVALMTISLWFMAWTPYLVINFSGIF-N
L-V--KISPLFTIWGSLFAKANAVYNPIVYGISHPKYRAALFAKFPSLAC-------A-A
EPSS--DAVSTTSGTTTVTD-NEKSNA---------------------------------
---------------------------------------------------------
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
----------------------------------MANQLSYSS----------------L
GWPY--QP----------NASVVDTMPKEMLY--------MIHEHWYAFPPMNPLWYSIL
GVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-MPTMTSNCF
A-ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAA-APLTHKKATL
LLLFVWIWSGGW-TILPFFG-W-----SRYVPEGNLTSCTVDYLT--KDWSSASYVVIYG
LAVYFLPLITMIYCYFFIVHAVAEHEKQLREQAKK-------------------------
--------------------------------------------------MN--------
--VASL------------------------------------------------------
----------RANADQQKQS------AECRLAKVAMMTVGLWFMAWTPYLIISWAGVF-S
SGT--RLTPLATIWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPSLAC------GS-G
ESGS--DVKSEASATTTMEE-KPKIPEA--------------------------------
---------------------------------------------------------
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
---------------------------------------MVES----------------T
TLVN--QT-WWY------NPTVD------------------IHPHWAKFDPIPDAVYYSV
GIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLKTISAF
M-KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSHRRAFL
MIIFVWMWSIVW-SVGPVFN-W-----GAYVPEGILTSCSFDYLS--TDPSTRSFILCMY
FCGFMLPIIIIAFCYFNIVMSVSNHEKEMAAMAKR-------------------------
--------------------------------------------------LN--------
--AKEL------------------------------------------------------
----------R--KAQAGAS------AEMKLAKISMVIITQFMLSWSPYAIIALLAQF-G
PAE--WVTPYAAELPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCCQFDEKE-C
EDAN--DAEEEVVASER--G-GESRDAAQMKEMMAMMQKMQAQQAAYQPPPPPQGY--PP
QGYPPQGAYPPPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVDNQAYQA
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
----------------------------------------MGR----------------D
LRDN--ET-WWY------NPSIV------------------VHPHWREFDQVPDAVYYSL
GIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCF
L-KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFI
MIIFVWLWSVLW-AIGPIFG-W-----GAYTLEGVLCNCSFDYIS--RDSTTRSNILCMF
ILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKR-------------------------
--------------------------------------------------LN--------
--AKEL------------------------------------------------------
----------R--KAQAGAN------AEMRLAKISIVIVSQFLLSWSPYAVVALLAQF-G
PLE--WVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKE-T
EDDK--DAETEIPAGESSDA-APSADAAQMKEMMAMMQKMQQQQAAY----PPQGYAPPP
QGYPPQGY--PPQGYPPQGYPPQGYPP---PPQGAPPQ-GAPPAAPPQGVDNQAYQA
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
---------MMDVNSSGRPDLYGHLRSFL-LPEVGRGLPDLSPDGGA------------D
PVAGSWAPHLLS------EVTASPAPTWDAPPDNASGCGEQIN--------YGRVEKVVI
GSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDL
IGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAK
MILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GYTIYST
AVAFYIPMSVMLFMYYQIY-------KAARKSAAKHKF----------------------
---------------------------------PGFPRV----EPDSVIALNG-------
--IVKL----------------------QK---------EVEECAN--------------
----LSRLLKHERKNISIFK------REQKAATTLGIIVGAFTVCWLPFFLLSTARPFIC
GTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYR----NINR--
------KLSAAGMHEALKLAERPERPEF------------VLQNADY-------------
--------------------------------------------CRKKGHDS-----
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
------------------------------------------------------------
------MPHLLS---GFLEVTASPAPTWDAPPDNVSGCGEQIN--------YGRVEKVVI
GSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDL
IGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAK
MILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GYTIYST
AVAFYIPMSVMLFMYYQIY-------KAARKSAAKHKF----------------------
---------------------------------PGFPRV----QPESVISLNG-------
--VVKL----------------------QK---------EVEECAN--------------
----LSRLLKHERKNISIFK------REQKAATTLGIIVGAFTVCWLPFFLLSTARPFIC
GTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRPTSRSLLQCQYR----NINR--
------KLSAAGMHEALKLAERPERSEF------------VLQNSDH-------------
--------------------------------------------CGKKGHDT-----
>    31=p A47425 serotonin receptor 5HT-7 - rat
------------------------------------------------------------
------MPHLLS---GFLEVTASPAPTWDAPPDNVSGCGEQIN--------YGRVEKVVI
GSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDL
IGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAK
MILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GYTIYST
AVAFYIPMSVMLFMYYQIY-------KAARKSAAKHKF----------------------
---------------------------------PGFPRV----QPESVISLNG-------
--VVKL----------------------QK---------EVEECAN--------------
----LSRLLKHERKNISIFK------REQKAATTLGIIVGAFTVCWLPFFLLSTARPFIC
GTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYR----NINR--
------KLSAAGMHEALKLAERPERSEF------------VLQNSDH-------------
--------------------------------------------CGKKGHDT-----
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
----------MDVLSP--------------------------------------------
---------------GQGNNTTSPPAPFET-GGNTTGISDVT---------VSYQ--VIT
SLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQV
L-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAA
LISLTWLIGFLI-SIPPMLG-WRTPEDRSDPD---ACTISKDH----------GYTIYST
FGAFYIPLLLMLVLYGRIF-------RAARFRIRK-------------------------
--------------TVKKVEKTGADTRHGASPAPQPKKS-----------VNGESGSR--
-------NWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAG--
PTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF-C
ESSC-HMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC----RQ----
------------------------------------------------------------
---------------------------------------------------------
>    33=p A35181 serotonin receptor class 1A - rat
----------MDVFSF--------------------------------------------
---------------GQGNNTTASQEPFGT-GGNVTSISDVT---------FSYQ--VIT
SLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQV
L-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAA
LISLTWLIGFLI-SIPPMLG-WRTPEDRSDPD---ACTISKDH----------GYTIYST
FGAFYIPLLLMLVLYGRIF-------RAARFRIRK-------------------------
--------------TVRKVEKKGAGTSLGTSSAPPPKKS-----------LNGQPGSG--
-------DWRRCAENRAVGTPCTNGAVRQGDDEATLEVIEVHRVGNSKEHLPLPSESG--
SNSYAPACLERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF-C
ESSC-HMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC----RR----
------------------------------------------------------------
---------------------------------------------------------
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
MANFTFGDLALDVARMG-----GLASTPSGLRSTGLTTPGLSPTGLV------------T
SDFN--DSYGLT---GQFINGSHSSRSRDNASANDTSATNMTDDRYWSLTVYSHEHLVLT
SVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEI
S-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILL
MIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK----------GYTIFST
VGAFYLPMLVMMIIYIRIW-------LVARSRIRKDKFQMTKARLKTEETTLVASPKTEY
SVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSS---
-------SERLKQIQIETAEAFANGCA----EEASIAMLERQ-CNNGKKISSNDTPYS--
-----------RTREKLELK------RERKAARTLAIITGAFLICWLPFFIIALIGPF-V
DPE--GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYR----RGHR--
------------------------------------------------------------
---------------------------------------------------------
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
MANFTFGDLALDVARMG-----GLASTPSGLRSTGLTTPGLSPTGLV------------T
SDFN--DSYGLT---GQFINGSHSSRSRDNASANDTSATNMTDDRYWSLTVYSHEHLVLT
SVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEI
S-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILL
MIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK----------GYTIFST
VGAFYLPMLVMMIIYIRIW-------LVARSRIRKDKFQMTKARLKTEETTLVASPKTEY
SVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSS---
-------SERLKQIQIETAEAFANGCA----EEASIAMLERQ-CNNGKKISSNDTPYS--
-----------RTREKLELK------RERKAARTLAIITGAFLICWLPFFIIALIGPF-V
DPE--GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYR----RGHR--
------------------------------------------------------------
---------------------------------------------------------
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
-MEGAEGQEELDWEAL-------YLRLP--LQNCSWNSTGWEPNWNV------------T
VVPN--TTWW------------QASAPFDTPAALVRAAAK--------------------
AVVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACLV-MPLGAVYEV
V-QRWT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIHASTAKRVGM
MIACVWTVSFFV-CIAQLLG-WKDPDWNQRVSEDLRCVVSQDV----------GYQIFAT
ASSFYVPVLIILILYWRIY-------QTARKRIR--------------------------
-------------------RRRGATARGGVGPPP---------VPAGGALVAGGGSGGIA
AAVVAVIGRPLPTISETTTTGFTNVSS----NNTSP---EKQSCANGLEADPPTTGYGAV
AAAYYPSLVRRKPKEAADSK------RERKAAKTLAIITGAFVACWLPFFVLAILVPT-C
DCE---VSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRLLCGRRV----RRRR--
------A---------------PQ------------------------------------
---------------------------------------------------------
