>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
-------------------MNGTEG--------------------------------DNF
YV-PFSNKTG-------LARSPYEYPQY-------YLAEPW---------KYSALAAYMF
FLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-FTVTMYTSMN-GYF
V--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGNF-RFGNTHAIMGVAFT
WIMALAC-AAPPLVG-WS-----RYIPEGMQCSCGPDYYTLNPNFNNESYVVYMFVVHFL
VPFVIIFFCYGRLLCTVKEAAAAQQ-----------------------------------
------------------------------------------------------------
-----------------------ESA----------------------------------
-------STQKAEKEVTRMVVLMVIGFLVCWVPYASVAFYIFTHQGS---DFGATFMTLP
AFFAKSSALYNPVIYILMNKQFRNCMITTLCC-----GKNPLGDDE-SGA-STSK-TEVS
SVS-TSPVSPA-------------------------------------------------
---------------------------------------------
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
-------------------MNGTEG--------------------------------PNF
YV-PFSNITG-------VVRSPFEQPQY-------YLAEPW---------QFSMLAAYMF
LLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTTLYTSLH-GYF
V--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSNF-RFGENHAIMGVAFT
WVMALAC-AAPPLVG-WS-----RYIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHFT
IPMIVIFFCYGQLVFTVKEAAAQQQ-----------------------------------
------------------------------------------------------------
-----------------------ESA----------------------------------
-------TTQKAEKEVTRMVIIMVIFFLICWLPYASVAMYIFTHQGS---NFGPIFMTLP
AFFAKTASIYNPIIYIMMNKQFRNCMLTSLCC-----GKNPLGDDE-ASA-TASK-TETS
QVA-PA------------------------------------------------------
---------------------------------------------
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
-------------------MNGTEG--------------------------------INF
YV-PMSNKTG-------VVRSPFEYPQY-------YLAEPW---------KYRLVCCYIF
FLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-FTVTFYTAWN-GYF
V--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGNF-RFSATHAMMGIAFT
WVMAFSC-AAPPLFG-WS-----RYMPEGMQCSCGPDYYTHNPDYHNESYVLYMFVIHFI
IPVVVIFFSYGRLICKVREAAAQQQ-----------------------------------
------------------------------------------------------------
-----------------------ESA----------------------------------
-------TTQKAEKEVTRMVILMVLGFMLAWTPYAVVAFWIFTNKGA---DFTATLMAVP
AFFSKSSSLYNPIIYVLMNKQFRNCMITTICC-----GKNPFGDEDVSSTVSQSK-TEVS
SVS-SSQVSPA-------------------------------------------------
---------------------------------------------
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
-------------------MNGTEG--------------------------------KNF
YV-PMSNRTG-------LVRSPFEYPQY-------YLAEPW---------QFKILALYLF
FLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-FTVTFYTAIN-GYF
V--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGSF-KFSSSHAFAGIAFT
WVMALAC-AAPPLFG-WS-----RYIPEGMQCSCGPDYYTLNPDYNNESYVIYMFVCHFI
LPVAVIFFTYGRLVCTVKAAAAQQQ-----------------------------------
------------------------------------------------------------
-----------------------DSA----------------------------------
-------STQKAEREVTKMVILMVFGFLIAWTPYATVAAWIFFNKGA---DFSAKFMAIP
AFFSKSSALYNPVIYVLLNKQFRNCMLTTIFC-----GKNPLGDDE-SSTVSTSK-TEVS
SVS-PA------------------------------------------------------
---------------------------------------------
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
-------------------MNGTEG--------------------------------NNF
YV-PLSNRTG-------LVRSPFEYPQY-------YLAEPW---------QFKLLAVYMF
FLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-FTVTFYTAIN-GYF
A--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGSF-KFSSTHASAGIAFT
WVMAMAC-AAPPLVG-WS-----RYIPEGIQCSCGPDYYTLNPEYNNESYVLYMFICHFI
LPVTIIFFTYGRLVCTVKAAAAQQQ-----------------------------------
------------------------------------------------------------
-----------------------DSA----------------------------------
-------STQKAEREVTKMVILMVLGFLVAWTPYATVAAWIFFNKGA---AFSAQFMAIP
AFFSKTSALYNPVIYVLLNKQFRSCMLTTLFC-----GKNPLGDEE-SSTVSTSK-TEVS
SVS-PA------------------------------------------------------
---------------------------------------------
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
-------------------MKQVPE------------------------------FHEDF
YI-PIPLDINNL-----SAYSPFLVPQD-------HLGNQG---------IFMAMSVFMF
FIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-SPLSFYSFFN-RYF
I--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGNF-TFKTPHAIAGCILP
WISALAA-SLPPLFG-WS-----RYIPEGLQCSCGPDWYTTNNKYNNESYVMFLFCFCFA
VPFGTIVFCYGQLLITLKLAAKAQA-----------------------------------
------------------------------------------------------------
-----------------------DSA----------------------------------
-------STQKAEREVTKMVVVMVLGFLVCWAPYASFSLWIVSHRGE---EFDLRMATIP
SCLSKASTVYNPVIYVLMNKQFRSCMMKMVC------GKN-IEEDE-AST-SSQV-TQVS
SVA-PEK-----------------------------------------------------
---------------------------------------------
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
-------------------MRKMSE--------------------------------EEF
YL------FKNI-----SSVGPWDGPQY-------HIAPVW---------AFYLQAAFMG
TVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-VFPVFVASCN-GYF
V--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNF-RFSSKHALTVVLAT
WTIGIGV-SIPPFFG-WS-----RFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFI
VPLSLICFSYTQLLRALKAVAAQQQ-----------------------------------
------------------------------------------------------------
-----------------------ESA----------------------------------
-------TTQKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRNH---GLDLRLVTIP
SFFSKSACIYNPIIYCFMNKQFQACIMKMVC------GKA-MTDES-DTC-SSQK-TEVS
TVS-STQVGPN-------------------------------------------------
---------------------------------------------
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------DLAETVIA-STISIVNQVS-GYF
V--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNV-RFDAKLAIVGIAFS
WIWAAVW-TAPPIFG-WS-----RYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCI
TPLSIIVLCYLQVWLAIRAVAKQQK-----------------------------------
------------------------------------------------------------
-----------------------ESE----------------------------------
-------STQKAEKEVTRMVVVMVLAFC--------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
MAQQWSLQRLAGRHPQDSYEDSTQS--------------------------------SIF
TY-TNSN----------STRGPFEGPNY-------HIAPRW---------VYHLTSVWMI
FVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISVVNQVY-GYF
V--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNV-RFDAKLAIVGIAFS
WIWAAVW-TAPPIFG-WS-----RYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCI
TPLSIIVLCYLQVWLAIRAVAKQQK-----------------------------------
------------------------------------------------------------
-----------------------ESE----------------------------------
-------STQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGY---PFHPLMAALP
AFFAKSATIYNPVIYVFMNRQFRNCILQLF-------GKK-VDDGS-ELS-SASK-TEVS
SVS---SVSPA-------------------------------------------------
---------------------------------------------
>    10== Z68193   1 human Red Opsin <>[]
MAQQWSLQRLAGRHPQDSYEDSTQS--------------------------------SIF
TY-TNSN----------STRGPFEGPNY-------HIAPRW---------VYHLTSVWMI
FVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISIVNQVS-GYF
V--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNV-RFDAKLAIVGIAFS
WIWSAVW-TAPPIFG-WS-----RYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCI
IPLAIIMLCYLQVWLAIRAVAKQQK-----------------------------------
------------------------------------------------------------
-----------------------ESE----------------------------------
-------STQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGY---AFHPLMAALP
AYFAKSATIYNPVIYVFMNRQFRNCILQLF-------GKK-VDDGS-ELS-SASK-TEVS
SVS---SVSPA-------------------------------------------------
---------------------------------------------
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
MTEAWNVAVFAARRSRDD-DDTTRG--------------------------------SVF
TY-TNTN----------NTRGPFEGPNY-------HIAPRW---------VYNLVSFFMI
IVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-STISVFNQIF-GYF
I--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGNI-KFDSKLAIIGIVFS
WVWAWGW-SAPPIFG-WS-----RYWPHGLKTSCGPDVFSGSVELGCQSFMLTLMITCCF
LPLFIIIVCYLQVWMAIRAVAAQQK-----------------------------------
------------------------------------------------------------
-----------------------ESE----------------------------------
-------STQKAEREVSRMVVVMIVAFCICWGPYASFVSFAAANPGY---AFHPLAAALP
AYFAKSATIYNPVIYVFMNRQFRNCIMQLF-------GKK-VDDGS-EAS-TTSR-TEVS
SVS-NSSVAPA-------------------------------------------------
---------------------------------------------
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
MA-AWE-AAFAARRRHEE-EDTTRD--------------------------------SVF
TY-TNSN----------NTRGPFEGPNY-------HIAPRW---------VYNLTSVWMI
FVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVIA-STISVINQIS-GYF
I--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGNI-KFDGKLAVAGILFS
WLWSCAW-TAPPIFG-WS-----RYWPHGLKTSCGPDVFSGSSDPGVQSYMVVLMVTCCF
FPLAIIILCYLQVWLAIRAVAAQQK-----------------------------------
------------------------------------------------------------
-----------------------ESE----------------------------------
-------STQKAEKEVSRMVVVMIVAYCFCWGPYTFFACFAAANPGY---AFHPLAAALP
AYFAKSATIYNPIIYVFMNRQFRNCILQLF-------GKK-VDDGS-EVS-T-SR-TEVS
SVS-NSSVSPA-------------------------------------------------
---------------------------------------------
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
-----------------------MS--------------------------------SNS
SQ-APPN----------GTPGPFDGPQW------PYQAPQS---------TYVGVAVLMG
TVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-SSVSLSNNIN-GFF
V--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGDF-QFQRRHAVSGCAFT
WGWALLW-SAPPLLG-WS-----SYVPEGLRTSCGPNWYTGGSN--NNSYILSLFVTCFV
LPLSLILFSYTNLLLTLRAAAAQQK-----------------------------------
------------------------------------------------------------
-----------------------EAD----------------------------------
-------TTQRAEREVTRMVIVMVMAFLLCWLPYSTFALVVATHKGI---IIQPVLASLP
SYFSKTATVYNPIIYVFMNKQFQSCLLEMLCCGY--QPQR-TGKAS-PGT-PGPH-ADVT
AAGLRNKVMPAHPV----------------------------------------------
---------------------------------------------
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
-MESGNVS--SS-------LFGNVS--------------------------------TAL
R--PEARLSA------ETRLLGWNVPPEELR----HIPEHWLTYPEPPESMNYLLGTLYI
FFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK--TPIFIYNSFH-QGY
A--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--KMTHGKAIAMIIFI
YMYATPW-VVACYTETWG-----RFVPEGYLTSCTFDYLTDN--FDTRLFVACIFFFSFV
CPTTMITYYYSQIVGHVFSHEKALR-----------------------------------
------------------------------------------------------------
-----------------------DQAKKMNVESL--------------------------
-RSNVDKNKETAEIRIAKAAITICFLFFCSWTPYGVMSLIGAFGDKT---LLTPGATMIP
ACACKMVACIDPFVYAISHPRYRMELQKRCPWL--ALNEK-APESS-AVA-STST-TQEP
QQT------TAA------------------------------------------------
---------------------------------------------
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
-MEYHNVS---S-------VLGNVS--------------------------------SVL
R--PDARLSA------ESRLLGWNVPPDELR----HIPEHWLIYPEPPESMNYLLGTLYI
FFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMIK--TPIFIYNSFH-QGY
A--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--KMTHGKAIAMIIFI
YLYATPW-VVACYTESWG-----RFVPEGYLTSCTFDYLTDN--FDTRLFVACIFFFSFV
CPTTMITYYYSQIVGHVFSHEKALR-----------------------------------
------------------------------------------------------------
-----------------------DQAKKMNVDSL--------------------------
-RSNVDKSKEAAEIRIAKAAITICFLFFASWTPYGVMSLIGAFGDKT---LLTPGATMIP
ACTCKMVACIDPFVYAISHPRYRMELQKRCPWL--AISEK-APESR-AAI-STST-TQEQ
QQT------TAA------------------------------------------------
---------------------------------------------
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
-MEP---------------LCNASE--------------------------------PPL
R--PEAR-SSGNG---DLQFLGWNVPPDQIQ----YIPEHWLTQLEPPASMHYMLGVFYI
FLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIF--NSFH-RGF
AIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNIII
WLYCTPW-VVLPLTQFWD-----RFVPEGYLTSCSFDYLSDN--FDTRLFVGTIFFFSFV
CPTLMILYYYSQIVGHVFSHEKALR-----------------------------------
------------------------------------------------------------
-----------------------EQAKKMNVESL--------------------------
-RSNVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKS---LLTQGATMIP
ACTCKLVACIDPFVYAISHPRYRLELQKRCPWL--GVNEK-SGEIS-SAQ-STTT-QEQQ
QTT------AA-------------------------------------------------
---------------------------------------------
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
-MDA---------------LCNASE--------------------------------PPL
R--PEARMSSGSD---ELQFLGWNVPPDQIQ----YIPEHWLTQLEPPASMHYMLGVFYI
FLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIFIYNSFH-RGF
A--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNIII
WLYCTPW-VVLPLTQFWD-----RFVPEGYLTSCSFDYLSDN--FDTRLFVGTIFLFSFV
VPTLMILYYYSQIVGHVFNHEKALR-----------------------------------
------------------------------------------------------------
-----------------------EQAKKMNVESL--------------------------
-RSNVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKS---LLTPGATMIP
ACTCKLVACIEPFVYAISHPRYRMELQKRCPWL--GVNEK-SGEAS-SAQ-STTT-QEQT
QQT------SAA------------------------------------------------
---------------------------------------------
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
-------------------MTNATG--------------------------------PQM
AYYGAASMDFGYP---EGVSIVDFVRPEIKP----YVHQHWYNYPPVNPMWHYLLGVIYL
FLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTTN-VPFFTYNCFSGGVW
M--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNGP-KLTTGKAVVFALIS
WVIAIGC-ALPPFFG-WG-----NYILEGILDSCSYDYLTQD--FNTFSYNIFIFVFDYF
LPAAIIVFSYVFIVKAIFAHEAAMR-----------------------------------
------------------------------------------------------------
-----------------------AQAKKMNVSTL--------------------------
-RS-NEADAQRAEIRIAKTALVNVSLWFICWTPYALISLKGVMGDTS---GITPLVSTLP
ALLAKSCSCYNPFVYAISHPKYRLAITQHLPWF--CVHET-ETKSN-DDS-QSNS-TVAQ
DKA---------------------------------------------------------
---------------------------------------------
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
-------------------MANVTG--------------------------------PQM
AFYGSGAATFGYP---EGMTVADFVPDRVKH----MVLDHWYNYPPVNPMWHYLLGVVYL
FLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-FPPFCYNCFSGGRW
M--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNGP-KLTQGKATFMCGLA
WVISVGW-SLPPFFG-WG-----SYTLEGILDSCSYDYFTRD--MNTITYNICIFIFDFF
LPASVIVFSYVFIVKAIFAHEAAMR-----------------------------------
------------------------------------------------------------
-----------------------AQAKKMNVTNL--------------------------
-RS-NEAETQRAEIRIAKTALVNVSLWFICWTPYAAITIQGLLGNAE---GITPLLTTLP
ALLAKSCSCYNPFVYAISHPKFRLAITQHLPWF--CVHEK-DPNDV-EEN-QSSN-TQTQ
EKS---------------------------------------------------------
---------------------------------------------
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
-MESFAV------------AAAQLG--------------------------------PHF
A-----PLS--------NGSVVDKVTPDMAH----LISPYWNQFPAMDPIWAKILTAYMI
MIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETW
V--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKM---
------------------------YVPEGNLTSCGIDYLERD--WNPRSYLIFYSIFVYY
IPLFLICYSYWFIIAAVSAHEKAMR-----------------------------------
------------------------------------------------------------
-----------------------EQAKKMNVKSL--------------------------
-RS-SEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLFKF-E---GLTPLNTIWG
ACFAKSAACYNPIVYGISHPKYRLALKEKCPCC--VFGKV-DDGKS-SDA-QSQA-TASE
AES------KA-------------------------------------------------
---------------------------------------------
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
-MESFAV------------AAAQLG--------------------------------PHF
A-----PLS--------NGSVVDKVTPDMAH----LISPYWNQFPAMDPIWAKILTAYMI
MIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETW
V--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKIAYI
WFMSSIW-CLAPAFG-WS-----RYVPEGNLTSCGIDYLERD--WNPRSYLIFYSIFVYY
IPLFLICYSYWFIIAAVSAHEKAMR-----------------------------------
------------------------------------------------------------
-----------------------EQAKKMNVKSL--------------------------
-RS-SEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLFKF-E---GLTPLNTIWG
ACFAKSAACYNPIVYGISHPKYRLALKEKCPCC--VFGKV-DDGKS-SDA-QSQA-TASE
AES------KA-------------------------------------------------
---------------------------------------------
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
-MDSFAA------------VATQLG--------------------------------PQF
A-----APS--------NGSVVDKVTPDMAH----LISPYWDQFPAMDPIWAKILTAYMI
IIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETW
V--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKIAYI
WFMSTIWCCLAPVFG-WS-----RYVPEGNLTSCGIDYLERD--WNPRSYLIFYSIFVYY
IPLFLICYSYWFIIAAVSAHEKAMR-----------------------------------
------------------------------------------------------------
-----------------------EQAKKMNVKSL--------------------------
-RS-SEDADKSAEGKLAKVALVTISLWFMAWTPYLVINCMGLFKF-E---GLTPLNTIWG
ACFAKSAACYNPIVYGISHPKYRLALKEKCPCC--VFGKV-DDGKS-SEA-QSQA-TTSE
AES------KA-------------------------------------------------
---------------------------------------------
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
-MERSHLPETPF-------DLAHSG--------------------------------PRF
Q-----AQSSG------NGSVLDNVLPDMAH----LVNPYWSRFAPMDPMMSKILGLFTL
AIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ETW
V--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGINGT-PMTIKTSIMKILFI
WMMAVFW-TVMPLIG-WS-----AYVPEGNLTACSIDYMTRM--WNPRSYLITYSLFVYY
TPLFLICYSYWFIIAAVAAHEKAMR-----------------------------------
------------------------------------------------------------
-----------------------EQAKKMNVKSL--------------------------
-RS-SEDCDKSAEGKLAKVALTTISLWFMAWTPYLVICYFGLFKI-D---GLTPLTTIWG
ATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMC--VFGNT-DEPKP-DAP-ASDTETTSE
ADS------KA-------------------------------------------------
---------------------------------------------
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
-MERSLLPEPPL-------AMALLG--------------------------------PRF
E-----AQTGG------NRSVLDNVLPDMAP----LVNPHWSRFAPMDPTMSKILGLFTL
VILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ETW
V--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGINGT-PMTIKTSIMKIAFI
WMMAVFW-TIMPLIG-WS-----SYVPEGNLTACSIDYMTRQ--WNPRSYLITYSLFVYY
TPLFMICYSYWFIIATVAAHEKAMR-----------------------------------
------------------------------------------------------------
-----------------------DQAKKMNVKSL--------------------------
-RS-SEDCDKSAENKLAKVALTTISLWFMAWTPYLIICYFGLFKI-D---GLTPLTTIWG
ATFAKTSAVYNPIVYGISHPNDRLVLKEKCPMC--VCGTT-DEPKP-DAP-PSDTETTSE
AES------KD-------------------------------------------------
---------------------------------------------
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
-------------------MIAVSG--------------------------------PSY
E-----AFSYGGQARFNNQTVVDKVPPDMLH----LIDANWYQYPPLNPMWHGILGFVIG
MLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-SPPMVINCYY-ETW
V--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSGK-PLSINGALIRIIAI
WLFSLGW-TIAPMFG-WN-----RYVPEGNMTACGTDYFNRG--LLSASYLVCYGIWVYF
VPLFLIIYSYWFIIQAVAAHEKNMR-----------------------------------
------------------------------------------------------------
-----------------------EQAKKMNVASL--------------------------
-RS-SENQNTSAECKLAKVALMTISLWFMAWTPYLVINFSGIFNL-V---KISPLFTIWG
SLFAKANAVYNPIVYGISHPKYRAALFAKFPSL--ACAA--EPSSD-AVS-TTSG-TTTV
TDN------EKSNA----------------------------------------------
---------------------------------------------
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
---------------------MANQ--------------------------------LSY
S-----SLGWPYQ---PNASVVDTMPKEMLY----MIHEHWYAFPPMNPLWYSILGVAMI
ILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-MPTMTSNCFA-ETW
I--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAAA-PLTHKKATLLLLFV
WIWSGGW-TILPFFG-WS-----RYVPEGNLTSCTVDYLTKD--WSSASYVVIYGLAVYF
LPLITMIYCYFFIVHAVAEHEKQLR-----------------------------------
------------------------------------------------------------
-----------------------EQAKKMNVASL--------------------------
-RANADQQKQSAECRLAKVAMMTVGLWFMAWTPYLIISWAGVFSSGT---RLTPLATIWG
SVFAKANSCYNPIVYGISHPRYKAALYQRFPSL--ACGSG-ESGSD-VKS-EASA-TTTM
EEK------PKIPEA---------------------------------------------
---------------------------------------------
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
---------------------MVES--------------------------------TTL
V-----NQTWWY-----NPTV--------------DIHPHWAKFDPIPDAVYYSVGIFIG
VVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLKTISAFM-KKW
I--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSHRRAFLMIIFV
WMWSIVW-SVGPVFN-WG-----AYVPEGILTSCSFDYLSTD--PSTRSFILCMYFCGFM
LPIIIIAFCYFNIVMSVSNHEKEMA-----------------------------------
------------------------------------------------------------
-----------------------AMAKRLNAKEL--------------------------
-RK-AQ-AGASAEMKLAKISMVIITQFMLSWSPYAIIALLAQFGPAE---WVTPYAAELP
VLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCCQFD-EKECE-DAN-DAEE-EVVA
SER----GGESRDAAQMKEMMAMMQKMQAQQAAYQP---PPPPQGYPPQGYPPQGAYPPP
QGYPPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVDNQAYQA
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
----------------------MGR--------------------------------DLR
D-----NETWWY-----NPSI--------------VVHPHWREFDQVPDAVYYSLGIFIG
ICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFL-KKW
I--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFV
WLWSVLW-AIGPIFG-WG-----AYTLEGVLCNCSFDYISRD--STTRSNILCMFILGFF
GPILIIFFCYFNIVMSVSNHEKEMA-----------------------------------
------------------------------------------------------------
-----------------------AMAKRLNAKEL--------------------------
-RK-AQ-AGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLE---WVTPYAAQLP
VMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFD-DKETE-DDK-DAET-EIPA
GES--SDAAPSADAAQMKEMMAMMQKMQQQQAAYPPQGYAPPPQGYPPQGYPPQGY--PP
QGYPPQGYPP---PPQGAPPQGAPP------AAPPQGVDNQAYQA
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
MMDVNSSGRPDL-------YGHLRSFL---LPEVGRGLPDLSPDG--GADPVAGSWAPHL
LS----EVTA-------SPAPTWDAPPDNASGCG--------EQINYGRVEKVVIGSILT
LITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKW
I--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSV
WLLSASI-TLPPLFG-WA-----QNVNDDKVCLISQDF----------GYTIYSTAVAFY
IPMSVMLFMYYQIYKAARKSAAKHKFP--------------GFPR---------------
---V------------------E---------PDSVI-----------------------
-----ALNGIVKLQ--------KEVEECANLSRLL------------------KHER---
----KNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTF
LWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRK-L-----SAA-GMHE-ALKL
AER------PERPEFVL------------QNADY--------------------------
-------------------------------------CRKKGHDS
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
--------------------------------------------------------MPHL
LS-GFLEVTA-------SPAPTWDAPPDNVSGCG--------EQINYGRVEKVVIGSILT
LITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKW
I--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSV
WLLSASI-TLPPLFG-WA-----QNVNDDKVCLISQDF----------GYTIYSTAVAFY
IPMSVMLFMYYQIYKAARKSAAKHKFP--------------GFPR---------------
---V------------------Q---------PESVI-----------------------
-----SLNGVVKLQ--------KEVEECANLSRLL------------------KHER---
----KNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTC
LWLGYANSLINPFIYAFFNRDLRPTSRSLLQCQYRNINRK-L-----SAA-GMHE-ALKL
AER------PERSEFVL------------QNSDH--------------------------
-------------------------------------CGKKGHDT
>    31=p A47425 serotonin receptor 5HT-7 - rat
--------------------------------------------------------MPHL
LS-GFLEVTA-------SPAPTWDAPPDNVSGCG--------EQINYGRVEKVVIGSILT
LITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKW
I--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSV
WLLSASI-TLPPLFG-WA-----QNVNDDKVCLISQDF----------GYTIYSTAVAFY
IPMSVMLFMYYQIYKAARKSAAKHKFP--------------GFPR---------------
---V------------------Q---------PESVI-----------------------
-----SLNGVVKLQ--------KEVEECANLSRLL------------------KHER---
----KNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTC
LWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRK-L-----SAA-GMHE-ALKL
AER------PERSEFVL------------QNSDH--------------------------
-------------------------------------CGKKGHDT
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
-MDVLSPGQ---------------------------------------------------
-----GNNTT-------SPPAPFETGGNTT------------GISDVTVSYQVITSLLLG
TLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NKW
T--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLT
WLIGFLI-SIPPMLG-WRTP---EDRSDPDACTISKDH----------GYTIYSTFGAFY
IPLLLMLVLYGRIFRAARFRIRKTV-----------------------------------
----KKVEKTGADTRHGASPAPQ---------PKKSVNGESGSRNWRLGVESKAGGAL--
-----CANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAG--PTPCAPASFERKNERN
AEA-KRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESS-C-HMPTLLGAII
NWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ-----------------------
------------------------------------------------------------
---------------------------------------------
>    33=p A35181 serotonin receptor class 1A - rat
-MDVFSFGQ---------------------------------------------------
-----GNNTT-------ASQEPFGTGGNVT------------SISDVTFSYQVITSLLLG
TLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NKW
T--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLT
WLIGFLI-SIPPMLG-WRTP---EDRSDPDACTISKDH----------GYTIYSTFGAFY
IPLLLMLVLYGRIFRAARFRIRKTV-----------------------------------
----RKVEKKGAGTSLGTSSAPP---------PKKSLNGQPGSGDWRRCAENRAVGTP--
-----CTNGAVRQGDDEATLEVIEVHRVGNSKEHLPLPSESG--SNSYAPACLERKNERN
AEA-KRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESS-C-HMPALLGAII
NWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRR-----------------------
------------------------------------------------------------
---------------------------------------------
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
-MANFTFGDLALDVARMGGLASTPSG----LRSTGLTTPGLSPTGLVTSDFNDS---YGL
TG-QFINGSH-------SSRSRDNASANDTSATN-MTDDRYWSLTVYSHEHLVLTSVILG
LFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KVW
F--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMVV
WIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK----------GYTIFSTVGAFY
LPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNSP
DSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSS----------SERLK
QIQIETAEAFANGCAEEASIAMLERQ-CNNGKKI-------------------SSNDTPY
SRT-REKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPFVDPE---GIPPFARSFV
LWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYRRGHR---------------------
------------------------------------------------------------
---------------------------------------------
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
-MANFTFGDLALDVARMGGLASTPSG----LRSTGLTTPGLSPTGLVTSDFNDS---YGL
TG-QFINGSH-------SSRSRDNASANDTSATN-MTDDRYWSLTVYSHEHLVLTSVILG
LFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KVW
F--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMVV
WIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK----------GYTIFSTVGAFY
LPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNSP
DSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSS----------SERLK
QIQIETAEAFANGCAEEASIAMLERQ-CNNGKKI-------------------SSNDTPY
SRT-REKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPFVDPE---GIPPFARSFV
LWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYRRGHR---------------------
------------------------------------------------------------
---------------------------------------------
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
-------------------MEGAEGQEELDWEALYLRLP------LQNCSWNSTGWEPNW
NV-TVVPNTTWW-----QASAPFDTPAA--------------------LVRAAAKAVVLG
LLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACLV-MPLGAVYEVV-QRW
T--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIHASTAKRVGMMIACV
WTVSFFV-CIAQLLG-WKDPDWNQRVSEDLRCVVSQDV----------GYQIFATASSFY
VPVLIILILYWRIYQTARKRIRRRR-----------------------------------
----------GATARGGVGPPPV---------PAGGALVAGGGSGGIAAAVVAVIGRPLP
TISETTTTGFTNVSSNNTSP---EKQSCANGLEADPPTTGYGAVAAAYYPSLVRRKP---
----KEAADSKRERKAAKTLAIITGAFVACWLPFFVLAILVPTCD---C-EVSPVLTSLS
LWLGYFNSTLNPVIYTVFSPEFRHAFQRLLCGRRVRRRRA--------------------
---------PQ-------------------------------------------------
---------------------------------------------
