>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
----------------------------------------MNG----------------T
E--GDNFYVP---------FSNKTGLARSPYEYPQY------YLAEPWK---------YS
ALAAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-FTVTMYT
SMN-GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGN-FRFGNTHA
IMGVAFTWIMALAC-AAPPLVG-W-----SRYIPEGMQCSCGPDYYTLNPNFNNESYVVY
MFVVHFLVPFVIIFFCYGRLLCTV----KEAAAAQQ------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------ESASTQK------AEKEVTRMVVLMVIGFLVCWVPYASVAFYIFT
HQGS---DFGATFMTLPAFFAKSSALYNPVIYILMNKQFRNCMITTLCC--------GKN
PLGDDE--SGASTSKTEVSSVS-TSPVSPA------------------------------
-----------------------------------------------------------
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
----------------------------------------MNG----------------T
E--GPNFYVP---------FSNITGVVRSPFEQPQY------YLAEPWQ---------FS
MLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTTLYT
SLH-GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSN-FRFGENHA
IMGVAFTWVMALAC-AAPPLVG-W-----SRYIPEGMQCSCGIDYYTLKPEVNNESFVIY
MFVVHFTIPMIVIFFCYGQLVFTV----KEAAAQQQ------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------ESATTQK------AEKEVTRMVIIMVIFFLICWLPYASVAMYIFT
HQGS---NFGPIFMTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSLCC--------GKN
PLGDDE--ASATASKTE------TSQVAPA------------------------------
-----------------------------------------------------------
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
----------------------------------------MNG----------------T
E--GINFYVP---------MSNKTGVVRSPFEYPQY------YLAEPWK---------YR
LVCCYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-FTVTFYT
AWN-GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGN-FRFSATHA
MMGIAFTWVMAFSC-AAPPLFG-W-----SRYMPEGMQCSCGPDYYTHNPDYHNESYVLY
MFVIHFIIPVVVIFFSYGRLICKV----REAAAQQQ------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------ESATTQK------AEKEVTRMVILMVLGFMLAWTPYAVVAFWIFT
NKGA---DFTATLMAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTICC--------GKN
PFGDEDVSSTVSQSKTEVSSVS-SSQVSPA------------------------------
-----------------------------------------------------------
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
----------------------------------------MNG----------------T
E--GKNFYVP---------MSNRTGLVRSPFEYPQY------YLAEPWQ---------FK
ILALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-FTVTFYT
AIN-GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSSSHA
FAGIAFTWVMALAC-AAPPLFG-W-----SRYIPEGMQCSCGPDYYTLNPDYNNESYVIY
MFVCHFILPVAVIFFTYGRLVCTV----KAAAAQQQ------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------DSASTQK------AEREVTKMVILMVFGFLIAWTPYATVAAWIFF
NKGA---DFSAKFMAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTIFC--------GKN
PLGDDE-SSTVSTSKTEVSS------VSPA------------------------------
-----------------------------------------------------------
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
----------------------------------------MNG----------------T
E--GNNFYVP---------LSNRTGLVRSPFEYPQY------YLAEPWQ---------FK
LLAVYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-FTVTFYT
AIN-GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSSTHA
SAGIAFTWVMAMAC-AAPPLVG-W-----SRYIPEGIQCSCGPDYYTLNPEYNNESYVLY
MFICHFILPVTIIFFTYGRLVCTV----KAAAAQQQ------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------DSASTQK------AEREVTKMVILMVLGFLVAWTPYATVAAWIFF
NKGA---AFSAQFMAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTLFC--------GKN
PLGDEE-SSTVSTSKTEVSS------VSPA------------------------------
-----------------------------------------------------------
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
----------------------------------------MKQ----------------V
PEFHEDFYIPIP-----LDINNLS--AYSPFLVPQD------HLGNQGI---------FM
AMSVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-SPLSFYS
FFN-RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGN-FTFKTPHA
IAGCILPWISALAA-SLPPLFG-W-----SRYIPEGLQCSCGPDWYTTNNKYNNESYVMF
LFCFCFAVPFGTIVFCYGQLLITL----KLAAKAQA------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------DSASTQK------AEREVTKMVVVMVLGFLVCWAPYASFSLWIVS
HRGE---EFDLRMATIPSCLSKASTVYNPVIYVLMNKQFRSCMM-KMVC--------GKN
-IEEDE--ASTSSQVTQVSS------VAPEK-----------------------------
-----------------------------------------------------------
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
----------------------------------------MRK----------------M
S--EEEFYL----------FKNIS--SVGPWDGPQY------HIAPVWA---------FY
LQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-VFPVFVA
SCN-GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGN-FRFSSKHA
LTVVLATWTIGIGV-SIPPFFG-W-----SRFIPEGLQCSCGPDWYTVGTKYRSESYTWF
LFIFCFIVPLSLICFSYTQLLRAL----KAVAAQQQ------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------ESATTQK------AEREVSRMVVVMVGSFCVCYVPYAAFAMYMVN
NRNH---GLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIM-KMVC--------GKA
-MTDES--DTCSSQKTEVSTVS-STQVGPN------------------------------
-----------------------------------------------------------
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------DLAETVIA-STISIVN
QVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDAKLA
IVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYMIV
LMVTCCITPLSIIVLCYLQVWLAI----RAVAKQQK------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------ESESTQK------AEKEVTRMVVVMVLAFC---------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
----------------------------------------MAQQWSLQRLAGRHPQDSYE
DSTQSSIFT----------YTNSNS-TRGPFEGPNY------HIAPRWV---------YH
LTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISVVN
QVY-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGN-VRFDAKLA
IVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYMIV
LMVTCCITPLSIIVLCYLQVWLAI----RAVAKQQK------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------ESESTQK------AEKEVTRMVVVMVLAFCFCWGPYAFFACFAAA
NPGY---PFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCIL-QLF---------GKK
-VDDGS--ELSSASKTEVSSV---SSVSPA------------------------------
-----------------------------------------------------------
>    10== Z68193   1 human Red Opsin <>[]
----------------------------------------MAQQWSLQRLAGRHPQDSYE
DSTQSSIFT----------YTNSNS-TRGPFEGPNY------HIAPRWV---------YH
LTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISIVN
QVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDAKLA
IVGIAFSWIWSAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYMIV
LMVTCCIIPLAIIMLCYLQVWLAI----RAVAKQQK------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------ESESTQK------AEKEVTRMVVVMIFAYCVCWGPYTFFACFAAA
NPGY---AFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCIL-QLF---------GKK
-VDDGS--ELSSASKTEVSSV---SSVSPA------------------------------
-----------------------------------------------------------
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
----------------------------------------MTEAWNVAVFAARRSRDD-D
DTTRGSVFT----------YTNTNN-TRGPFEGPNY------HIAPRWV---------YN
LVSFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-STISVFN
QIF-GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGN-IKFDSKLA
IIGIVFSWVWAWGW-SAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSVELGCQSFMLT
LMITCCFLPLFIIIVCYLQVWMAI----RAVAAQQK------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------ESESTQK------AEREVSRMVVVMIVAFCICWGPYASFVSFAAA
NPGY---AFHPLAAALPAYFAKSATIYNPVIYVFMNRQFRNCIM-QLF---------GKK
-VDDGS--EASTTSRTEVSSVS-NSSVAPA------------------------------
-----------------------------------------------------------
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
----------------------------------------MAA-WEAA-FAARRRHEE-E
DTTRDSVFT----------YTNSNN-TRGPFEGPNY------HIAPRWV---------YN
LTSVWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVIA-STISVIN
QIS-GYFI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGN-IKFDGKLA
VAGILFSWLWSCAW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSDPGVQSYMVV
LMVTCCFFPLAIIILCYLQVWLAI----RAVAAQQK------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------ESESTQK------AEKEVSRMVVVMIVAYCFCWGPYTFFACFAAA
NPGY---AFHPLAAALPAYFAKSATIYNPIIYVFMNRQFRNCIL-QLF---------GKK
-VDDGS--EVST-SRTEVSSVS-NSSVSPA------------------------------
-----------------------------------------------------------
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
----------------------------------------MS-----------------S
NSSQAP----------------PNG-TPGPFDGPQW-----PYQAPQST---------YV
GVAVLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-SSVSLSN
NIN-GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGD-FQFQRRHA
VSGCAFTWGWALLW-SAPPLLG-W-----SSYVPEGLRTSCGPNWYTGGSNN--NSYILS
LFVTCFVLPLSLILFSYTNLLLTL----RAAAAQQK------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------EADTTQR------AEREVTRMVIVMVMAFLLCWLPYSTFALVVAT
HKGI---IIQPVLASLPSYFSKTATVYNPIIYVFMNKQFQSCLL-EMLCCGY----QPQR
-TGKAS--PGTPGPHADVTAAGLRNKVMPAHP---------V------------------
-----------------------------------------------------------
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
----------MESGNVSS------------SLFGNVSTA-LRP----------------E
ARLSAE---------------TRLLGWNVPPEELR-------HIPEHWLTYPEPPESMNY
LLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK--TPIFIYN
SFH-QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--KMTHGKA
IAMIIFIYMYATPW-VVACYTETW-----GRFVPEGYLTSCTFDYLT--DNFDTRLFVAC
IFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKK-----------------------
----------------------------------------------------MN------
-----VESL---------------------------------------------------
------------RSNVDKNKET------AEIRIAKAAITICFLFFCSWTPYGVMSLIGAF
GDKT---LLTPGATMIPACACKMVACIDPFVYAISHPRYRMELQKRCPWLAL--------
-NEKAP--ESSAVASTSTTQEP--QQTTAA------------------------------
-----------------------------------------------------------
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
----------MEYHNVS-------------SVLGNVSSV-LRP----------------D
ARLSAE---------------SRLLGWNVPPDELR-------HIPEHWLIYPEPPESMNY
LLGTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMIK--TPIFIYN
SFH-QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--KMTHGKA
IAMIIFIYLYATPW-VVACYTESW-----GRFVPEGYLTSCTFDYLT--DNFDTRLFVAC
IFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKK-----------------------
----------------------------------------------------MN------
-----VDSL---------------------------------------------------
------------RSNVDKSKEA------AEIRIAKAAITICFLFFASWTPYGVMSLIGAF
GDKT---LLTPGATMIPACTCKMVACIDPFVYAISHPRYRMELQKRCPWLAI--------
-SEKAP--ESRAAISTSTTQEQ--QQTTAA------------------------------
-----------------------------------------------------------
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
----------MEP-------------------LCNASEPPLRP----------------E
ARSSGN-------------GDLQFLGWNVPPDQIQ-------YIPEHWLTQLEPPASMHY
MLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIF--N
SFH-RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKA
VIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFDTRLFVGT
IFFFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKK-----------------------
----------------------------------------------------MN------
-----VESL---------------------------------------------------
------------RSNVDKSKET------AEIRIAKAAITICFLFFVSWTPYGVMSLIGAF
GDKS---LLTQGATMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWLGV--------
-NEKSG--EISSAQSTTTQEQ---QQTTAA------------------------------
-----------------------------------------------------------
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
----------MDA-------------------LCNASEPPLRP----------------E
ARMSSG------------SDELQFLGWNVPPDQIQ-------YIPEHWLTQLEPPASMHY
MLGVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIFIYN
SFH-RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKA
VIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFDTRLFVGT
IFLFSFVVPTLMILYYYSQIVGHVFNHEKALREQAKK-----------------------
----------------------------------------------------MN------
-----VESL---------------------------------------------------
------------RSNVDKSKET------AEIRIAKAAITICFLFFVSWTPYGVMSLIGAF
GDKS---LLTPGATMIPACTCKLVACIEPFVYAISHPRYRMELQKRCPWLGV--------
-NEKSG--EASSAQSTTTQEQT--QQTSAA------------------------------
-----------------------------------------------------------
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
--------------------------------MTNATGPQMAY----------------Y
GAASMDFGYP----------EGVSIVDFVRPEIKP-------YVHQHWYNYPPVNPMWHY
LLGVIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTTN-VPFFTYN
CFSGGVWM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNG-PKLTTGKA
VVFALISWVIAIGC-ALPPFFG-W-----GNYILEGILDSCSYDYLT--QDFNTFSYNIF
IFVFDYFLPAAIIVFSYVFIVKAIFAHEAAMRAQAKK-----------------------
----------------------------------------------------MN------
-----VSTL---------------------------------------------------
------------RS-NEADAQR------AEIRIAKTALVNVSLWFICWTPYALISLKGVM
GDTS---GITPLVSTLPALLAKSCSCYNPFVYAISHPKYRLAITQHLPWFCV------HE
-TETKS--NDDSQSNSTVAQDK-A------------------------------------
-----------------------------------------------------------
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
--------------------------------MANVTGPQMAF----------------Y
GSGAATFGYP----------EGMTVADFVPDRVKH-------MVLDHWYNYPPVNPMWHY
LLGVVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-FPPFCYN
CFSGGRWM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNG-PKLTQGKA
TFMCGLAWVISVGW-SLPPFFG-W-----GSYTLEGILDSCSYDYFT--RDMNTITYNIC
IFIFDFFLPASVIVFSYVFIVKAIFAHEAAMRAQAKK-----------------------
----------------------------------------------------MN------
-----VTNL---------------------------------------------------
------------RS-NEAETQR------AEIRIAKTALVNVSLWFICWTPYAAITIQGLL
GNAE---GITPLLTTLPALLAKSCSCYNPFVYAISHPKFRLAITQHLPWFCV------HE
-KDPND--VEENQSSNTQTQEK-S------------------------------------
-----------------------------------------------------------
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
----------MESF----------------AVAAAQLGPHFAP----------------L
S--------------------NGSVVDKVTPDMAH-------LISPYWNQFPAMDPIWAK
ILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGIN
LYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLA
LGKM---------------------------YVPEGNLTSCGIDYLE--RDWNPRSYLIF
YSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKK-----------------------
----------------------------------------------------MN------
-----VKSL---------------------------------------------------
------------RS-SEDAEKS------AEGKLAKVALVTITLWFMAWTPYLVINCMGLF
KF-E---GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------GK
-VDDGK--SSDAQSQA-TASEA-ESKA---------------------------------
-----------------------------------------------------------
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
----------MESF----------------AVAAAQLGPHFAP----------------L
S--------------------NGSVVDKVTPDMAH-------LISPYWNQFPAMDPIWAK
ILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGIN
LYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLA
LGKIAYIWFMSSIW-CLAPAFG-W-----SRYVPEGNLTSCGIDYLE--RDWNPRSYLIF
YSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKK-----------------------
----------------------------------------------------MN------
-----VKSL---------------------------------------------------
------------RS-SEDAEKS------AEGKLAKVALVTITLWFMAWTPYLVINCMGLF
KF-E---GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------GK
-VDDGK--SSDAQSQA-TASEA-ESKA---------------------------------
-----------------------------------------------------------
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
----------MDSF----------------AAVATQLGPQFAA----------------P
S--------------------NGSVVDKVTPDMAH-------LISPYWDQFPAMDPIWAK
ILTAYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGIN
LYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLA
LGKIAYIWFMSTIWCCLAPVFG-W-----SRYVPEGNLTSCGIDYLE--RDWNPRSYLIF
YSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKK-----------------------
----------------------------------------------------MN------
-----VKSL---------------------------------------------------
------------RS-SEDADKS------AEGKLAKVALVTISLWFMAWTPYLVINCMGLF
KF-E---GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------GK
-VDDGK--SSEAQSQA-TTSEA-ESKA---------------------------------
-----------------------------------------------------------
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
MER-----SHLPET----------------PFDLAHSGPRFQA----------------Q
SSG------------------NGSVLDNVLPDMAH-------LVNPYWSRFAPMDPMMSK
ILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIIN
FYY-ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIKTS
IMKILFIWMMAVFW-TVMPLIG-W-----SAYVPEGNLTACSIDYMT--RMWNPRSYLIT
YSLFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKK-----------------------
----------------------------------------------------MN------
-----VKSL---------------------------------------------------
------------RS-SEDCDKS------AEGKLAKVALTTISLWFMAWTPYLVICYFGLF
KI-D---GLTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMCVF------GN
-TDEPK--PDAPASDTETTSEA-DSKA---------------------------------
-----------------------------------------------------------
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
MER-----SLLPEP----------------PLAMALLGPRFEA----------------Q
TGG------------------NRSVLDNVLPDMAP-------LVNPHWSRFAPMDPTMSK
ILGLFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIIN
FYY-ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIKTS
IMKIAFIWMMAVFW-TIMPLIG-W-----SSYVPEGNLTACSIDYMT--RQWNPRSYLIT
YSLFVYYTPLFMICYSYWFIIATVAAHEKAMRDQAKK-----------------------
----------------------------------------------------MN------
-----VKSL---------------------------------------------------
------------RS-SEDCDKS------AENKLAKVALTTISLWFMAWTPYLIICYFGLF
KI-D---GLTPLTTIWGATFAKTSAVYNPIVYGISHPNDRLVLKEKCPMCVC------GT
-TDEPK--PDAPPSDTETTSEA-ESKD---------------------------------
-----------------------------------------------------------
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
--------------------------------MIAVSGPSYEA----------------F
SYGGQA------------RFNNQTVVDKVPPDMLH-------LIDANWYQYPPLNPMWHG
ILGFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-SPPMVIN
CYY-ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSG-KPLSINGA
LIRIIAIWLFSLGW-TIAPMFG-W-----NRYVPEGNMTACGTDYFN--RGLLSASYLVC
YGIWVYFVPLFLIIYSYWFIIQAVAAHEKNMREQAKK-----------------------
----------------------------------------------------MN------
-----VASL---------------------------------------------------
------------RS-SENQNTS------AECKLAKVALMTISLWFMAWTPYLVINFSGIF
NL-V---KISPLFTIWGSLFAKANAVYNPIVYGISHPKYRAALFAKFPSLAC-------A
-AEPSS--DAVSTTSGTTTVTD-NEKSNA-------------------------------
-----------------------------------------------------------
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
MAN---------------------------QLSYSSLGWPYQP-----------------
---------------------NASVVDTMPKEMLY-------MIHEHWYAFPPMNPLWYS
ILGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-MPTMTSN
CFA-ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAA-APLTHKKA
TLLLLFVWIWSGGW-TILPFFG-W-----SRYVPEGNLTSCTVDYLT--KDWSSASYVVI
YGLAVYFLPLITMIYCYFFIVHAVAEHEKQLREQAKK-----------------------
----------------------------------------------------MN------
-----VASL---------------------------------------------------
------------RANADQQKQS------AECRLAKVAMMTVGLWFMAWTPYLIISWAGVF
SSGT---RLTPLATIWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPSLAC------GS
-GESGS--DVKSEASATTTMEE-KPKIPEA------------------------------
-----------------------------------------------------------
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
---------------------------------------MVES----------------T
TLVNQTWWY------------NPTVD-----------------IHPHWAKFDPIPDAVYY
SVGIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLKTIS
AFM-KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSHRRA
FLMIIFVWMWSIVW-SVGPVFN-W-----GAYVPEGILTSCSFDYLS--TDPSTRSFILC
MYFCGFMLPIIIIAFCYFNIVMSVSNHEKEMAAMAKR-----------------------
----------------------------------------------------LN------
-----AKEL---------------------------------------------------
------------R--KAQAGAS------AEMKLAKISMVIITQFMLSWSPYAIIALLAQF
GPAE---WVTPYAAELPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCCQFDEKE
-CEDAN--DAEEEVVASER--G-GESRDAAQMKEMMAMMQKMQAQQAAYQPPPPPQGY--
PPQGYPPQGAYPPPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVDNQAYQA
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
----------------------------------------MGR----------------D
LRDNETWWY------------NPSIV-----------------VHPHWREFDQVPDAVYY
SLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTIS
CFL-KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRA
FIMIIFVWLWSVLW-AIGPIFG-W-----GAYTLEGVLCNCSFDYIS--RDSTTRSNILC
MFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKR-----------------------
----------------------------------------------------LN------
-----AKEL---------------------------------------------------
------------R--KAQAGAN------AEMRLAKISIVIVSQFLLSWSPYAVVALLAQF
GPLE---WVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKE
-TEDDK--DAETEIPAGESSDA-APSADAAQMKEMMAMMQKMQQQQAAY----PPQGYAP
PPQGYPPQGY--PPQGYPPQGYPPQGYPP---PPQGAPPQ-GAPPAAPPQGVDNQAYQA
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
M---------MDVNSSGRPDLYGHLRSFL-LPEVGRGLPDLSPDG--------------G
ADPVAGSWAPHLLS---EVTASPAPTWDAPPDNASG---CGEQIN--------YGRVEKV
VIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVT
DLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCM
AKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GYTIY
STAVAFYIPMSVMLFMYYQIY-------KAARKSAAKHKF--------------------
-------------PGF-----------------PRVE---------PDSVIALNG-----
-----IVKL---------------------QK---------EVEECAN------------
------LSRLLKHERKNISIFK------REQKAATTLGIIVGAFTVCWLPFFLLSTARPF
ICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYR---NINRK
-LSAAGMHEALKLAERPERPEFVLQNADYCRKK---------------------------
--------------------------------------------------GHDS-----
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
------------------------------------------------------------
--------MPHLLSGFLEVTASPAPTWDAPPDNVSG---CGEQIN--------YGRVEKV
VIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVT
DLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCM
AKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GYTIY
STAVAFYIPMSVMLFMYYQIY-------KAARKSAAKHKF--------------------
-------------PGF-----------------PRVQ---------PESVISLNG-----
-----VVKL---------------------QK---------EVEECAN------------
------LSRLLKHERKNISIFK------REQKAATTLGIIVGAFTVCWLPFFLLSTARPF
ICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRPTSRSLLQCQYR---NINRK
-LSAAGMHEALKLAERPERSEFVLQNSDHCGKK---------------------------
--------------------------------------------------GHDT-----
>    31=p A47425 serotonin receptor 5HT-7 - rat
------------------------------------------------------------
--------MPHLLSGFLEVTASPAPTWDAPPDNVSG---CGEQIN--------YGRVEKV
VIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVT
DLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCM
AKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GYTIY
STAVAFYIPMSVMLFMYYQIY-------KAARKSAAKHKF--------------------
-------------PGF-----------------PRVQ---------PESVISLNG-----
-----VVKL---------------------QK---------EVEECAN------------
------LSRLLKHERKNISIFK------REQKAATTLGIIVGAFTVCWLPFFLLSTARPF
ICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYR---NINRK
-LSAAGMHEALKLAERPERSEFVLQNSDHCGKK---------------------------
--------------------------------------------------GHDT-----
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
----------MDV---------------------------LSP-----------------
------------------GQGNNTTSPPAPFETGGN----TTGISDVTVSY-------QV
ITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALY
QVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRA
AALISLTWLIGFLI-SIPPMLG-WRTP-EDRSDPDA--CTISKDH----------GYTIY
STFGAFYIPLLLMLVLYGRIF-------RAARFRIRK-----------------------
----------------TVKKVEKTGADTRHGASPAPQ---------PKKS--VNGESGSR
---------NWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAG
P--TPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF
CESSC--HMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC------RQ
------------------------------------------------------------
-----------------------------------------------------------
>    33=p A35181 serotonin receptor class 1A - rat
----------MDV---------------------------FSF-----------------
------------------GQGNNTTASQEPFGTGGN----VTSISDVTFSY-------QV
ITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALY
QVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRA
AALISLTWLIGFLI-SIPPMLG-WRTP-EDRSDPDA--CTISKDH----------GYTIY
STFGAFYIPLLLMLVLYGRIF-------RAARFRIRK-----------------------
----------------TVRKVEKKGAGTSLGTSSAPP---------PKKS--LNGQPGSG
---------DWRRCAENRAVGTPCTNGAVRQGDDEATLEVIEVHRVGNSKEHLPLPSESG
S--NSYAPACLERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF
CESSC--HMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC------RR
------------------------------------------------------------
-----------------------------------------------------------
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
MANFTFGDLALDVARMG-----GLASTPSGLRSTGLTTPGLSPTGLV------------T
SDFNDSYGLT-------GQFINGSHSSRSRDNASANDTSATNMTDDRYWSLTVYSHEHLV
LTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVS
EIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRI
LLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK----------GYTIF
STVGAFYLPMLVMMIIYIRIW-------LVARSRIRKDKFQMTKARLKTEETTLVASPKT
EYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSSS
E---RLKQI-------QIETAEAFANGCA----EEASIAMLERQ-CNNGKKISSNDTPYS
------------RT-REKLELK------RERKAARTLAIITGAFLICWLPFFIIALIGPF
VDPE---GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYR----RGHR
------------------------------------------------------------
-----------------------------------------------------------
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
MANFTFGDLALDVARMG-----GLASTPSGLRSTGLTTPGLSPTGLV------------T
SDFNDSYGLT-------GQFINGSHSSRSRDNASANDTSATNMTDDRYWSLTVYSHEHLV
LTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVS
EIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRI
LLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK----------GYTIF
STVGAFYLPMLVMMIIYIRIW-------LVARSRIRKDKFQMTKARLKTEETTLVASPKT
EYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSSS
E---RLKQI-------QIETAEAFANGCA----EEASIAMLERQ-CNNGKKISSNDTPYS
------------RT-REKLELK------RERKAARTLAIITGAFLICWLPFFIIALIGPF
VDPE---GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYR----RGHR
------------------------------------------------------------
-----------------------------------------------------------
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
MEGAE-GQEELDWEALY-------LRLP--LQNCSWNSTGWEPNWNV------------T
VVPNTTWWQ-----------------ASAPFDTPAALVR-------------------AA
AKAVVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACLV-MPLGAVY
EVV-QRWT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIHASTAKRV
GMMIACVWTVSFFV-CIAQLLG-WKDPDWNQRVSEDLRCVVSQDV----------GYQIF
ATASSFYVPVLIILILYWRIY-------QTARKRIRR-----------------------
----------------------RRGATARGGVGPPPV---------PAGGALVAGGGSGG
IAAAVVAVIGRPLPTISETTTTGFTNVSSNNTSP-------EKQSCANGLEADPPTTGYG
AVAAAYYPSLVRRKPKEAADSK------RERKAAKTLAIITGAFVACWLPFFVLAILVPT
CDCE----VSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRLLCGRRV----RRRR
------------------------------------------------------------
-------------------------------------APQ-------------------
