>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
--------------------MNGTE--G-------------------DNFYVPFSNKTG-
-------------------------------LARSPYEYPQY----------------YL
AEPW---------KYSA-----LAAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILL
NLAMANLFMVLFG-FTVTMYTSMN-GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAI
ERYIVICKPMGNF-RFGNTHAIMGVAFTWIMALACAAP-PLVG-WS-----RYIPEGMQC
SCGPDYYTLNPNFNNESYVVYMFVVHFLVPFVIIFFCYGRLLCTVKEAAAAQQESA----
------------------------------------------------------------
------------------------------------------------------------
-----------------STQKAEKEVTRMVVLMVIGFLVCWVPYASVAFYIFT-HQGS--
DFGATFMTLPAFFAKSSALYNPVIYILMNKQFRNCMITTLC-----C----GKNPLGDDE
-SGA-STSK-TEVSSVS-TSPVSPA-----------------------------------
-----------------------------------------------------------
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
--------------------MNGTE--G-------------------PNFYVPFSNITG-
-------------------------------VVRSPFEQPQY----------------YL
AEPW---------QFSM-----LAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILL
NLAVADLFMVFGG-FTTTLYTSLH-GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAI
ERYVVVCKPMSNF-RFGENHAIMGVAFTWVMALACAAP-PLVG-WS-----RYIPEGMQC
SCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIVIFFCYGQLVFTVKEAAAQQQESA----
------------------------------------------------------------
------------------------------------------------------------
-----------------TTQKAEKEVTRMVIIMVIFFLICWLPYASVAMYIFT-HQGS--
NFGPIFMTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSLC-----C----GKNPLGDDE
-ASA-TASK-TETSQVA-PA----------------------------------------
-----------------------------------------------------------
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
--------------------MNGTE--G-------------------INFYVPMSNKTG-
-------------------------------VVRSPFEYPQY----------------YL
AEPW---------KYRL-----VCCYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILV
NLAVADLFMACFG-FTVTFYTAWN-GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAI
ERYIVVCKPMGNF-RFSATHAMMGIAFTWVMAFSCAAP-PLFG-WS-----RYMPEGMQC
SCGPDYYTHNPDYHNESYVLYMFVIHFIIPVVVIFFSYGRLICKVREAAAQQQESA----
------------------------------------------------------------
------------------------------------------------------------
-----------------TTQKAEKEVTRMVILMVLGFMLAWTPYAVVAFWIFT-NKGA--
DFTATLMAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTIC-----C----GKNPFGDED
VSSTVSQSK-TEVSSVS-SSQVSPA-----------------------------------
-----------------------------------------------------------
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
--------------------MNGTE--G-------------------KNFYVPMSNRTG-
-------------------------------LVRSPFEYPQY----------------YL
AEPW---------QFKI-----LALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILV
NLAVAGTIMVCFG-FTVTFYTAIN-GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAI
ERYIVVCKPMGSF-KFSSSHAFAGIAFTWVMALACAAP-PLFG-WS-----RYIPEGMQC
SCGPDYYTLNPDYNNESYVIYMFVCHFILPVAVIFFTYGRLVCTVKAAAAQQQDSA----
------------------------------------------------------------
------------------------------------------------------------
-----------------STQKAEREVTKMVILMVFGFLIAWTPYATVAAWIFF-NKGA--
DFSAKFMAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTIF-----C----GKNPLGDDE
-SSTVSTSK-TEVSSVS-PA----------------------------------------
-----------------------------------------------------------
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
--------------------MNGTE--G-------------------NNFYVPLSNRTG-
-------------------------------LVRSPFEYPQY----------------YL
AEPW---------QFKL-----LAVYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILV
NLAVAGAIMVCFG-FTVTFYTAIN-GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAI
ERYIVVCKPMGSF-KFSSTHASAGIAFTWVMAMACAAP-PLVG-WS-----RYIPEGIQC
SCGPDYYTLNPEYNNESYVLYMFICHFILPVTIIFFTYGRLVCTVKAAAAQQQDSA----
------------------------------------------------------------
------------------------------------------------------------
-----------------STQKAEREVTKMVILMVLGFLVAWTPYATVAAWIFF-NKGA--
AFSAQFMAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTLF-----C----GKNPLGDEE
-SSTVSTSK-TEVSSVS-PA----------------------------------------
-----------------------------------------------------------
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
--------------------MKQVPEFH-------------------EDFYIPIPLDIN-
-----------------------------NLSAYSPFLVPQD----------------HL
GNQG---------IFMA-----MSVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILV
NLSIANLFVAIFG-SPLSFYSFFN-RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAF
ERWLVICKPLGNF-TFKTPHAIAGCILPWISALAASLP-PLFG-WS-----RYIPEGLQC
SCGPDWYTTNNKYNNESYVMFLFCFCFAVPFGTIVFCYGQLLITLKLAAKAQADSA----
------------------------------------------------------------
------------------------------------------------------------
-----------------STQKAEREVTKMVVVMVLGFLVCWAPYASFSLWIVS-HRGE--
EFDLRMATIPSCLSKASTVYNPVIYVLMNKQFRSCMM-KMV-----C----GKN-IEEDE
-AST-SSQV-TQVSSVA-PEK---------------------------------------
-----------------------------------------------------------
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
--------------------MRKMS--E-------------------EEFYL-----FK-
-----------------------------NISSVGPWDGPQY----------------HI
APVW---------AFYL-----QAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILV
NVSFGGFLLCIFS-VFPVFVASCN-GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAF
ERYIVICKPFGNF-RFSSKHALTVVLATWTIGIGVSIP-PFFG-WS-----RFIPEGLQC
SCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLICFSYTQLLRALKAVAAQQQESA----
------------------------------------------------------------
------------------------------------------------------------
-----------------TTQKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVN-NRNH--
GLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIM-KMV-----C----GKA-MTDES
-DTC-SSQK-TEVSTVS-STQVGPN-----------------------------------
-----------------------------------------------------------
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----DLAETVIA-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISW
ERWLVVCKPFGNV-RFDAKLAIVGIAFSWIWAAVWTAP-PIFG-WS-----RYWPHGLKT
SCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQQKESE----
------------------------------------------------------------
------------------------------------------------------------
-----------------STQKAEKEVTRMVVVMVLAFC----------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
MAQQWS-LQRLAGRHPQDSYEDSTQ--S-------------------SIFTYTNSN----
-------------------------------STRGPFEGPNY----------------HI
APRW---------VYHL-----TSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILV
NLAVADLAETVIA-STISVVNQVY-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISW
ERWMVVCKPFGNV-RFDAKLAIVGIAFSWIWAAVWTAP-PIFG-WS-----RYWPHGLKT
SCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQQKESE----
------------------------------------------------------------
------------------------------------------------------------
-----------------STQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAA-NPGY--
PFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCIL-QLF----------GKK-VDDGS
-ELS-SASK-TEVSSV---SSVSPA-----------------------------------
-----------------------------------------------------------
>    10== Z68193   1 human Red Opsin <>[]
MAQQWS-LQRLAGRHPQDSYEDSTQ--S-------------------SIFTYTNSN----
-------------------------------STRGPFEGPNY----------------HI
APRW---------VYHL-----TSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILV
NLAVADLAETVIA-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISW
ERWLVVCKPFGNV-RFDAKLAIVGIAFSWIWSAVWTAP-PIFG-WS-----RYWPHGLKT
SCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAIRAVAKQQKESE----
------------------------------------------------------------
------------------------------------------------------------
-----------------STQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAA-NPGY--
AFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCIL-QLF----------GKK-VDDGS
-ELS-SASK-TEVSSV---SSVSPA-----------------------------------
-----------------------------------------------------------
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
MTEAWNVAVFAARRSRDD--DDTTR--G-------------------SVFTYTNTN----
-------------------------------NTRGPFEGPNY----------------HI
APRW---------VYNL-----VSFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILV
NLAFVDLVETLVA-STISVFNQIF-GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISW
ERWFVVCKPFGNI-KFDSKLAIIGIVFSWVWAWGWSAP-PIFG-WS-----RYWPHGLKT
SCGPDVFSGSVELGCQSFMLTLMITCCFLPLFIIIVCYLQVWMAIRAVAAQQKESE----
------------------------------------------------------------
------------------------------------------------------------
-----------------STQKAEREVSRMVVVMIVAFCICWGPYASFVSFAAA-NPGY--
AFHPLAAALPAYFAKSATIYNPVIYVFMNRQFRNCIM-QLF----------GKK-VDDGS
-EAS-TTSR-TEVSSVS-NSSVAPA-----------------------------------
-----------------------------------------------------------
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
MA-AWE-AAFAARRRHEE--EDTTR--D-------------------SVFTYTNSN----
-------------------------------NTRGPFEGPNY----------------HI
APRW---------VYNL-----TSVWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILV
NLAVADLGETVIA-STISVINQIS-GYFI--LGHPMCVVEGYTVSACGITALWSLAIISW
ERWFVVCKPFGNI-KFDGKLAVAGILFSWLWSCAWTAP-PIFG-WS-----RYWPHGLKT
SCGPDVFSGSSDPGVQSYMVVLMVTCCFFPLAIIILCYLQVWLAIRAVAAQQKESE----
------------------------------------------------------------
------------------------------------------------------------
-----------------STQKAEKEVSRMVVVMIVAYCFCWGPYTFFACFAAA-NPGY--
AFHPLAAALPAYFAKSATIYNPIIYVFMNRQFRNCIL-QLF----------GKK-VDDGS
-EVS-T-SR-TEVSSVS-NSSVSPA-----------------------------------
-----------------------------------------------------------
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
------------------------M--S-------------------SNSSQAPPN----
-------------------------------GTPGPFDGPQW---------------PYQ
APQS---------TYVG-----VAVLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILV
NLAVADLLVTLCG-SSVSLSNNIN-GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILAL
ERYVVVCKPLGDF-QFQRRHAVSGCAFTWGWALLWSAP-PLLG-WS-----SYVPEGLRT
SCGPNWYTGGSN--NNSYILSLFVTCFVLPLSLILFSYTNLLLTLRAAAAQQKEAD----
------------------------------------------------------------
------------------------------------------------------------
-----------------TTQRAEREVTRMVIVMVMAFLLCWLPYSTFALVVAT-HKGI--
IIQPVLASLPSYFSKTATVYNPIIYVFMNKQFQSCLL-EML-----CCGYQPQR-TGKAS
-PGT-PGPH-ADVTAAGLRNKVMPAHPV--------------------------------
-----------------------------------------------------------
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
-MESGNVS--SS--------LFGNV--S-------------------TALR-------P-
-------------------------------EARLSA---E---TRLLGWNVPPEELRHI
PEHWLTYPEPPESMNYL-----LGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVI
NLAFCDFMMMVK--TPIFIYNSFH-QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAY
DRFNVITRPMEG--KMTHGKAIAMIIFIYMYATPWVVA-CYTETWG-----RFVPEGYLT
SCTFDYLTDN--FDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKKMN
VE------------------SLRS------------------------------------
------------------------------------------------------------
-------------NVDKNKETAEIRIAKAAITICFLFFCSWTPYGVMSLIGAF-GDKT--
LLTPGATMIPACACKMVACIDPFVYAISHPRYRMELQ-KRCPWL--AL---NEK-APESS
-AVA-STST-TQEPQQT------TAA----------------------------------
-----------------------------------------------------------
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
-MEYHNVS--SV--------L-GNV--S-------------------SVLR-------P-
-------------------------------DARLSA---E---SRLLGWNVPPDELRHI
PEHWLIYPEPPESMNYL-----LGTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVI
NLAFCDFMMMIK--TPIFIYNSFH-QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAY
DRYNVITRPMEG--KMTHGKAIAMIIFIYLYATPWVVA-CYTESWG-----RFVPEGYLT
SCTFDYLTDN--FDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKKMN
VD------------------SLRS------------------------------------
------------------------------------------------------------
-------------NVDKSKEAAEIRIAKAAITICFLFFASWTPYGVMSLIGAF-GDKT--
LLTPGATMIPACTCKMVACIDPFVYAISHPRYRMELQ-KRCPWL--AI---SEK-APESR
-AAI-STST-TQEQQQT------TAA----------------------------------
-----------------------------------------------------------
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
-ME--------P--------LCNAS--E-------------------PPLR-------P-
-------------------------------EAR-SSGNGD---LQFLGWNVPPDQIQYI
PEHWLTQLEPPASMHYM-----LGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVL
NLAVFDLIMCLK--APIF--NSFH-RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGY
DRYNVITKPMNR--NMTFTKAVIMNIIIWLYCTPWVVL-PLTQFWD-----RFVPEGYLT
SCSFDYLSDN--FDTRLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKKMN
VE------------------SLRS------------------------------------
------------------------------------------------------------
-------------NVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAF-GDKS--
LLTQGATMIPACTCKLVACIDPFVYAISHPRYRLELQ-KRCPWL--GV---NEK-SGEIS
-SAQ-STTT-QEQQQTT------AA-----------------------------------
-----------------------------------------------------------
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
-MD--------A--------LCNAS--E-------------------PPLR-------P-
-------------------------------EARMSSGSDE---LQFLGWNVPPDQIQYI
PEHWLTQLEPPASMHYM-----LGVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVL
NLAVFDLIMCLK--APIFIYNSFH-RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGY
DRYNVITKPMNR--NMTFTKAVIMNIIIWLYCTPWVVL-PLTQFWD-----RFVPEGYLT
SCSFDYLSDN--FDTRLFVGTIFLFSFVVPTLMILYYYSQIVGHVFNHEKALREQAKKMN
VE------------------SLRS------------------------------------
------------------------------------------------------------
-------------NVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAF-GDKS--
LLTPGATMIPACTCKLVACIEPFVYAISHPRYRMELQ-KRCPWL--GV---NEK-SGEAS
-SAQ-STTT-QEQTQQT------SAA----------------------------------
-----------------------------------------------------------
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
--------------------MTNAT--G-------------------PQMAY-----YG-
-------------------------------AASMDFGYPE---GVSIVDFVRPEIKPYV
HQHWYNYPPVNPMWHYL-----LGVIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVV
NLALSDLIMLTTN-VPFFTYNCFSGGVWM--FSPQYCEIYACLGAITGVCSIWLLCMISF
DRYNIICNGFNGP-KLTTGKAVVFALISWVIAIGCALP-PFFG-WG-----NYILEGILD
SCSYDYLTQD--FNTFSYNIFIFVFDYFLPAAIIVFSYVFIVKAIFAHEAAMRAQAKKMN
VS------------------TLRS------------------------------------
------------------------------------------------------------
--------------NEADAQRAEIRIAKTALVNVSLWFICWTPYALISLKGVM-GDTS--
GITPLVSTLPALLAKSCSCYNPFVYAISHPKYRLAIT-QHLPWF--CV---HET-ETKSN
-DDS-QSNS-TVAQDKA-------------------------------------------
-----------------------------------------------------------
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
--------------------MANVT--G-------------------PQMAF-----YG-
-------------------------------SGAATFGYPE---GMTVADFVPDRVKHMV
LDHWYNYPPVNPMWHYL-----LGVVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIV
NLALSDLIMLTTN-FPPFCYNCFSGGRWM--FSGTYCEIYAALGAITGVCSIWTLCMISF
DRYNIICNGFNGP-KLTQGKATFMCGLAWVISVGWSLP-PFFG-WG-----SYTLEGILD
SCSYDYFTRD--MNTITYNICIFIFDFFLPASVIVFSYVFIVKAIFAHEAAMRAQAKKMN
VT------------------NLRS------------------------------------
------------------------------------------------------------
--------------NEAETQRAEIRIAKTALVNVSLWFICWTPYAAITIQGLL-GNAE--
GITPLLTTLPALLAKSCSCYNPFVYAISHPKFRLAIT-QHLPWF--CV---HEK-DPNDV
-EEN-QSSN-TQTQEKS-------------------------------------------
-----------------------------------------------------------
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
------MESFAV--------AAAQL--G-------------------PHFA---------
---------------------------------PLS--------NGSVVDKVTPDMAHLI
SPYWNQFPAMDPIWAKI-----LTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVI
NLAISDFGIMITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISL
DRYQVIVKGMAGR-PMTIPLALGKM---------------------------YVPEGNLT
SCGIDYLERD--WNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMN
VK------------------SLRS------------------------------------
------------------------------------------------------------
--------------SEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLF-KF-E--
GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALK-EKCPCC--VF---GKV-DDGKS
-SDA-QSQA-TASEAES------KA-----------------------------------
-----------------------------------------------------------
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
------MESFAV--------AAAQL--G-------------------PHFA---------
---------------------------------PLS--------NGSVVDKVTPDMAHLI
SPYWNQFPAMDPIWAKI-----LTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVI
NLAISDFGIMITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISL
DRYQVIVKGMAGR-PMTIPLALGKIAYIWFMSSIW-CLAPAFG-WS-----RYVPEGNLT
SCGIDYLERD--WNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMN
VK------------------SLRS------------------------------------
------------------------------------------------------------
--------------SEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLF-KF-E--
GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALK-EKCPCC--VF---GKV-DDGKS
-SDA-QSQA-TASEAES------KA-----------------------------------
-----------------------------------------------------------
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
------MDSFAA--------VATQL--G-------------------PQFA---------
---------------------------------APS--------NGSVVDKVTPDMAHLI
SPYWDQFPAMDPIWAKI-----LTAYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVI
NLAISDFGIMITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISL
DRYQVIVKGMAGR-PMTIPLALGKIAYIWFMSTIWCCLAPVFG-WS-----RYVPEGNLT
SCGIDYLERD--WNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMN
VK------------------SLRS------------------------------------
------------------------------------------------------------
--------------SEDADKSAEGKLAKVALVTISLWFMAWTPYLVINCMGLF-KF-E--
GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALK-EKCPCC--VF---GKV-DDGKS
-SEA-QSQA-TTSEAES------KA-----------------------------------
-----------------------------------------------------------
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
-MERSHLPETPF--------DLAHS--G-------------------PRFQ---------
---------------------------------AQSSG------NGSVLDNVLPDMAHLV
NPYWSRFAPMDPMMSKI-----LGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVL
NLAFSDFCMMASQ-SPVMIINFYY-ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAF
DRYNVIVKGINGT-PMTIKTSIMKILFIWMMAVFWTVM-PLIG-WS-----AYVPEGNLT
ACSIDYMTRM--WNPRSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKKMN
VK------------------SLRS------------------------------------
------------------------------------------------------------
--------------SEDCDKSAEGKLAKVALTTISLWFMAWTPYLVICYFGLF-KI-D--
GLTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLK-EKCPMC--VF---GNT-DEPKP
-DAP-ASDTETTSEADS------KA-----------------------------------
-----------------------------------------------------------
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
-MERSLLPEPPL--------AMALL--G-------------------PRFE---------
---------------------------------AQTGG------NRSVLDNVLPDMAPLV
NPHWSRFAPMDPTMSKI-----LGLFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVL
NLAFSDFCMMASQ-SPVMIINFYY-ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAF
DRYNVIVKGINGT-PMTIKTSIMKIAFIWMMAVFWTIM-PLIG-WS-----SYVPEGNLT
ACSIDYMTRQ--WNPRSYLITYSLFVYYTPLFMICYSYWFIIATVAAHEKAMRDQAKKMN
VK------------------SLRS------------------------------------
------------------------------------------------------------
--------------SEDCDKSAENKLAKVALTTISLWFMAWTPYLIICYFGLF-KI-D--
GLTPLTTIWGATFAKTSAVYNPIVYGISHPNDRLVLK-EKCPMC--VC---GTT-DEPKP
-DAP-PSDTETTSEAES------KD-----------------------------------
-----------------------------------------------------------
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
--------------------MIAVS--G-------------------PSYE---------
---------------------------------AFSYGGQARFNNQTVVDKVPPDMLHLI
DANWYQYPPLNPMWHGI-----LGFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVI
NLAISNFLMMFCM-SPPMVINCYY-ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAF
DRYNVIVKGLSGK-PLSINGALIRIIAIWLFSLGWTIA-PMFG-WN-----RYVPEGNMT
ACGTDYFNRG--LLSASYLVCYGIWVYFVPLFLIIYSYWFIIQAVAAHEKNMREQAKKMN
VA------------------SLRS------------------------------------
------------------------------------------------------------
--------------SENQNTSAECKLAKVALMTISLWFMAWTPYLVINFSGIF-NL-V--
KISPLFTIWGSLFAKANAVYNPIVYGISHPKYRAALF-AKFPSL--AC----AA-EPSSD
-AVS-TTSG-TTTVTDN------EKSNA--------------------------------
-----------------------------------------------------------
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
----------------------MAN--Q-------------------LSYS---------
---------------------------------SLGWPYQP---NASVVDTMPKEMLYMI
HEHWYAFPPMNPLWYSI-----LGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVV
NLAFSDFCMMAFM-MPTMTSNCFA-ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITL
DRYNVIVRGMAAA-PLTHKKATLLLLFVWIWSGGWTIL-PFFG-WS-----RYVPEGNLT
SCTVDYLTKD--WSSASYVVIYGLAVYFLPLITMIYCYFFIVHAVAEHEKQLREQAKKMN
VA------------------SLRA------------------------------------
------------------------------------------------------------
-------------NADQQKQSAECRLAKVAMMTVGLWFMAWTPYLIISWAGVF-SSGT--
RLTPLATIWGSVFAKANSCYNPIVYGISHPRYKAALY-QRFPSL--AC---GSG-ESGSD
-VKS-EASA-TTTMEEK------PKIPEA-------------------------------
-----------------------------------------------------------
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
----------------------MVE--S-------------------TTLV---------
---------------------------------NQTWWY-----NPTV----------DI
HPHWAKFDPIPDAVYYS-----VGIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFII
NLAMSDLSFSAINGFPLKTISAFM-KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISI
DRYNVIGRPMAASKKMSHRRAFLMIIFVWMWSIVWSVG-PVFN-WG-----AYVPEGILT
SCSFDYLSTD--PSTRSFILCMYFCGFMLPIIIIAFCYFNIVMSVSNHEKEMAAMAKRLN
AK------------------ELRK------------------------------------
------------------------------------------------------------
--------------AQ-AGASAEMKLAKISMVIITQFMLSWSPYAIIALLAQF-GPAE--
WVTPYAAELPVLFAKASAIHNPIVYSVSHPKFREAIQ-TTFPWLLTCC---QFD-EKECE
-DAN-DAEE-EVVASER----GGESRDAAQMKEMMAMMQKMQAQQAAYQP---PPPPQGY
PPQGYPPQGAYPPPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVDNQAYQA
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
-----------------------MG--R-------------------DLRD---------
---------------------------------NETWWY-----NPSI----------VV
HPHWREFDQVPDAVYYS-----LGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFII
NLAFSDFTFSLVNGFPLMTISCFL-KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISI
DRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLWAIG-PIFG-WG-----AYTLEGVLC
NCSFDYISRD--STTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKRLN
AK------------------ELRK------------------------------------
------------------------------------------------------------
--------------AQ-AGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQF-GPLE--
WVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAIS-QTFPWVLTCC---QFD-DKETE
-DDK-DAET-EIPAGES--SDAAPSADAAQMKEMMAMMQKMQQQQAAYPPQGYAPPPQGY
PPQGYPPQGY--PPQGYPPQGYPP---PPQGAPPQGAPP------AAPPQGVDNQAYQA
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
-------------------MMDVNS-SG----RPDLYGHLRSFLLPEVGRGLPDLSPDG-
-----------GADPVAGSWAPHLLS---EVTASPA---PTW--DA------PPDNASGC
GEQ----INYGRVEKVV-----IGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIV
SLALADLSVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISI
DRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLP-PLFG-WA-----QNVNDDKVC
LISQDF----------GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKF------
--------PGFPRVEPDSVIALNG------------------------------------
----------------IVKLQKE------------------VEECAN-------------
-----LSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCS
CIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYR-SLL---------QCQYRNINRK
LSAA-GMHE-ALKLAER------PERPEFVL------------QNADYCRK---------
-------------------------------------------------KGHDS-----
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
------------------------------------------------------------
--------------------MPHLLSGFLEVTASPA---PTW--DA------PPDNVSGC
GEQ----INYGRVEKVV-----IGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIV
SLALADLSVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISI
DRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLP-PLFG-WA-----QNVNDDKVC
LISQDF----------GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKF------
--------PGFPRVQPESVISLNG------------------------------------
----------------VVKLQKE------------------VEECAN-------------
-----LSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCS
CIPLWVERTCLWLGYANSLINPFIYAFFNRDLRPTSR-SLL---------QCQYRNINRK
LSAA-GMHE-ALKLAER------PERSEFVL------------QNSDHCGK---------
-------------------------------------------------KGHDT-----
>    31=p A47425 serotonin receptor 5HT-7 - rat
------------------------------------------------------------
--------------------MPHLLSGFLEVTASPA---PTW--DA------PPDNVSGC
GEQ----INYGRVEKVV-----IGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIV
SLALADLSVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISI
DRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLP-PLFG-WA-----QNVNDDKVC
LISQDF----------GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKF------
--------PGFPRVQPESVISLNG------------------------------------
----------------VVKLQKE------------------VEECAN-------------
-----LSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCS
CIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYR-SLL---------QCQYRNINRK
LSAA-GMHE-ALKLAER------PERSEFVL------------QNSDHCGK---------
-------------------------------------------------KGHDT-----
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
--------------------MDVLS-PG--------------------------------
-------------------------------QGNNT--------TSPPAPFETGGNTTGI
S-------DVTVSYQVI-----TSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIG
SLAVTDLMVSVLV-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIAL
DRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIP-PMLG-WRTPEDRSDPD---AC
TISKDH----------GYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTG
ADTRHGASPAPQPKK-----SVNG--ESGSRNWRLGVESKAGGALCANGAVRQGDDGAAL
--EVIEVHRVGNSKEHLPLPSEAGPTPCAPAS------------------FERKNERNA-
------------EAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF-CESSC-
HMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFK-KII---------KCKFCRQ---
------------------------------------------------------------
-----------------------------------------------------------
>    33=p A35181 serotonin receptor class 1A - rat
--------------------MDVFS-FG--------------------------------
-------------------------------QGNNT--------TASQEPFGTGGNVTSI
S-------DVTFSYQVI-----TSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIG
SLAVTDLMVSVLV-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIAL
DRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIP-PMLG-WRTPEDRSDPD---AC
TISKDH----------GYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVRKVEKKG
AGTSLGTSSAPPPKK-----SLNG--QPGSGDWRRCAENRAVGTPCTNGAVRQGDDEATL
--EVIEVHRVGNSKEHLPLPSESGSNSYAPAC------------------LERKNERNA-
------------EAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF-CESSC-
HMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFK-KII---------KCKFCRR---
------------------------------------------------------------
-----------------------------------------------------------
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
------MANFTFGDL----ALDVAR-MGGLASTPS---GLRS-----TGLTTPGLSPTGL
VTSDFNDSYGLTGQFINGSHSSRSRD---NASANDT--------SATNM---TDDRYWSL
T-------VYSHEHLVL-----TSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLIL
SLAVADLMVAVLV-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAM
DRYWAVTS-IDYIRRRSARRILLMIMVVWIVALFISIP-PLFG-WRDPNN--DPDKTGTC
IISQDK----------GYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKAR
LKTEETTLVASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKL
PENANGVNSNSSSSERLKQIQIETAEAFANGCAEEASIAMLERQCNNGKKISSNDTPYS-
------------RTREKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPF-VDPE--
GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQ-KIL---------FGKYRRGHR-
------------------------------------------------------------
-----------------------------------------------------------
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
------MANFTFGDL----ALDVAR-MGGLASTPS---GLRS-----TGLTTPGLSPTGL
VTSDFNDSYGLTGQFINGSHSSRSRD---NASANDT--------SATNM---TDDRYWSL
T-------VYSHEHLVL-----TSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLIL
SLAVADLMVAVLV-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAM
DRYWAVTS-IDYIRRRSARRILLMIMVVWIVALFISIP-PLFG-WRDPNN--DPDKTGTC
IISQDK----------GYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKAR
LKTEETTLVASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKL
PENANGVNSNSSSSERLKQIQIETAEAFANGCAEEASIAMLERQCNNGKKISSNDTPYS-
------------RTREKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPF-VDPE--
GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQ-KIL---------FGKYRRGHR-
------------------------------------------------------------
-----------------------------------------------------------
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
-------MEGAEGQE----ELDWEA-LY---------------------LRLP-------
------------------------LQ---NCSWNSTGWEPNW--NVTVV---PNTTWWQA
S-------APFDTPAALVRAAAKAVVLGLLILATVVGNVFVIAAILLERHLRSAANNLIL
SLAVADLLVACLV-MPLGAVYEVV-QRWT--LGPELCDMWTSGDVLCCTASILHLVAIAL
DRYWAVTN-IDYIHASTAKRVGMMIACVWTVSFFVCIA-QLLG-WKDPDWNQRVSEDLRC
VVSQDV----------GYQIFATASSFYVPVLIILILYWRIYQTARKRIRR------RRG
ATARGGVGPPPVPAGGALV-AGGG----------------------------SGGIAAAV
---------VAVIGRPLPTISETTTTGFTNVSSNNTSPE--KQSCANGLEADPPTTGYGA
VAAAYYPSLVRRKPKEAADSKRERKAAKTLAIITGAFVACWLPFFVLAILVPT-CDCE--
-VSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQ-RLL---------CGRRVRRRRA
-----------------------PQ-----------------------------------
-----------------------------------------------------------
