>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
------------------------------------------------------------
---------------------MNGTE--GDNFYVP------FSNKTGLARSPYEYPQY--
------YLAEPWKYSALAAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMAN
LFMVLFG-FTVTMYTSMN-GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVI
CKPMGN-FRFGNTHAIMGVAFTWIMALAC-AAPPLVG-WSRYIPEGMQCSCGPDYYTLNP
NFNNESYVVYMFVVHFLVPFVIIFFCYGRLLCTV----KEAAAAQQ--------------
------------------------------------------------------------
------------------------------------------------------------
--------ESASTQKAEKEVTRMVVLMVIGFLVCWVPYASVAFYIFTHQGS---DFGATF
MTLPAFFAKSSALYNPVIYILMNKQFRNCMITTLCCG--KNPLGDDE--SGASTSKTEVS
SVS-TSPVSPA-------------------------------------------------
--------------------------------------------
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
------------------------------------------------------------
---------------------MNGTE--GPNFYVP------FSNITGVVRSPFEQPQY--
------YLAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVAD
LFMVFGG-FTTTLYTSLH-GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVV
CKPMSN-FRFGENHAIMGVAFTWVMALAC-AAPPLVG-WSRYIPEGMQCSCGIDYYTLKP
EVNNESFVIYMFVVHFTIPMIVIFFCYGQLVFTV----KEAAAQQQ--------------
------------------------------------------------------------
------------------------------------------------------------
--------ESATTQKAEKEVTRMVIIMVIFFLICWLPYASVAMYIFTHQGS---NFGPIF
MTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSLCCG--KNPLGDDE--ASATASKTETS
QVA------PA-------------------------------------------------
--------------------------------------------
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
------------------------------------------------------------
---------------------MNGTE--GINFYVP------MSNKTGVVRSPFEYPQY--
------YLAEPWKYRLVCCYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVAD
LFMACFG-FTVTFYTAWN-GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVV
CKPMGN-FRFSATHAMMGIAFTWVMAFSC-AAPPLFG-WSRYMPEGMQCSCGPDYYTHNP
DYHNESYVLYMFVIHFIIPVVVIFFSYGRLICKV----REAAAQQQ--------------
------------------------------------------------------------
------------------------------------------------------------
--------ESATTQKAEKEVTRMVILMVLGFMLAWTPYAVVAFWIFTNKGA---DFTATL
MAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTICCG--KNPFGDEDVSSTVSQSKTEVS
SVS-SSQVSPA-------------------------------------------------
--------------------------------------------
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
------------------------------------------------------------
---------------------MNGTE--GKNFYVP------MSNRTGLVRSPFEYPQY--
------YLAEPWQFKILALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAG
TIMVCFG-FTVTFYTAIN-GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVV
CKPMGS-FKFSSSHAFAGIAFTWVMALAC-AAPPLFG-WSRYIPEGMQCSCGPDYYTLNP
DYNNESYVIYMFVCHFILPVAVIFFTYGRLVCTV----KAAAAQQQ--------------
------------------------------------------------------------
------------------------------------------------------------
--------DSASTQKAEREVTKMVILMVFGFLIAWTPYATVAAWIFFNKGA---DFSAKF
MAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTIFCG--KNPLGDDE-SSTVSTSKTEVS
SVS------PA-------------------------------------------------
--------------------------------------------
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
------------------------------------------------------------
---------------------MNGTE--GNNFYVP------LSNRTGLVRSPFEYPQY--
------YLAEPWQFKLLAVYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAG
AIMVCFG-FTVTFYTAIN-GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVV
CKPMGS-FKFSSTHASAGIAFTWVMAMAC-AAPPLVG-WSRYIPEGIQCSCGPDYYTLNP
EYNNESYVLYMFICHFILPVTIIFFTYGRLVCTV----KAAAAQQQ--------------
------------------------------------------------------------
------------------------------------------------------------
--------DSASTQKAEREVTKMVILMVLGFLVAWTPYATVAAWIFFNKGA---AFSAQF
MAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTLFCG--KNPLGDEE-SSTVSTSKTEVS
SVS------PA-------------------------------------------------
--------------------------------------------
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
------------------------------------------------------------
---------------------MKQVPEFHEDFYIP--IPLDINNLS--AYSPFLVPQD--
------HLGNQGIFMAMSVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIAN
LFVAIFG-SPLSFYSFFN-RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVI
CKPLGN-FTFKTPHAIAGCILPWISALAA-SLPPLFG-WSRYIPEGLQCSCGPDWYTTNN
KYNNESYVMFLFCFCFAVPFGTIVFCYGQLLITL----KLAAKAQA--------------
------------------------------------------------------------
------------------------------------------------------------
--------DSASTQKAEREVTKMVVVMVLGFLVCWAPYASFSLWIVSHRGE---EFDLRM
ATIPSCLSKASTVYNPVIYVLMNKQFRSCMM-KMVCG--KN-IEEDE--ASTSSQVTQVS
SVA-PEK-----------------------------------------------------
--------------------------------------------
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
------------------------------------------------------------
---------------------MRKMS--EEEFYL-------FKNIS--SVGPWDGPQY--
------HIAPVWAFYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGG
FLLCIFS-VFPVFVASCN-GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVI
CKPFGN-FRFSSKHALTVVLATWTIGIGV-SIPPFFG-WSRFIPEGLQCSCGPDWYTVGT
KYRSESYTWFLFIFCFIVPLSLICFSYTQLLRAL----KAVAAQQQ--------------
------------------------------------------------------------
------------------------------------------------------------
--------ESATTQKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRNH---GLDLRL
VTIPSFFSKSACIYNPIIYCFMNKQFQACIM-KMVCG--KA-MTDES--DTCSSQKTEVS
TVS-STQVGPN-------------------------------------------------
--------------------------------------------
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------D
LAETVIA-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVV
CKPFGN-VRFDAKLAIVGIAFSWIWAAVW-TAPPIFG-WSRYWPHGLKTSCGPDVFSGSS
YPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAI----RAVAKQQK--------------
------------------------------------------------------------
------------------------------------------------------------
--------ESESTQKAEKEVTRMVVVMVLAFC----------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
------------------------------------------------------------
----------MAQQWSLQRLAGRHPQDSYEDSTQS--SIFTYTNSNS-TRGPFEGPNY--
------HIAPRWVYHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVAD
LAETVIA-STISVVNQVY-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVV
CKPFGN-VRFDAKLAIVGIAFSWIWAAVW-TAPPIFG-WSRYWPHGLKTSCGPDVFSGSS
YPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAI----RAVAKQQK--------------
------------------------------------------------------------
------------------------------------------------------------
--------ESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGY---PFHPLM
AALPAFFAKSATIYNPVIYVFMNRQFRNCILQLF------GKKVDDG-SELSSASKTEVS
SV---SSVSPA-------------------------------------------------
--------------------------------------------
>    10== Z68193   1 human Red Opsin <>[]
------------------------------------------------------------
----------MAQQWSLQRLAGRHPQDSYEDSTQS--SIFTYTNSNS-TRGPFEGPNY--
------HIAPRWVYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVAD
LAETVIA-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVV
CKPFGN-VRFDAKLAIVGIAFSWIWSAVW-TAPPIFG-WSRYWPHGLKTSCGPDVFSGSS
YPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAI----RAVAKQQK--------------
------------------------------------------------------------
------------------------------------------------------------
--------ESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGY---AFHPLM
AALPAYFAKSATIYNPVIYVFMNRQFRNCILQLF------GKKVDDG-SELSSASKTEVS
SV---SSVSPA-------------------------------------------------
--------------------------------------------
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
------------------------------------------------------------
----------MTEAWNVAVFAARRSRD-DDDTTRG--SVFTYTNTNN-TRGPFEGPNY--
------HIAPRWVYNLVSFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVD
LVETLVA-STISVFNQIF-GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVV
CKPFGN-IKFDSKLAIIGIVFSWVWAWGW-SAPPIFG-WSRYWPHGLKTSCGPDVFSGSV
ELGCQSFMLTLMITCCFLPLFIIIVCYLQVWMAI----RAVAAQQK--------------
------------------------------------------------------------
------------------------------------------------------------
--------ESESTQKAEREVSRMVVVMIVAFCICWGPYASFVSFAAANPGY---AFHPLA
AALPAYFAKSATIYNPVIYVFMNRQFRNCIMQLF------GKKVDDG-SEASTTSRTEVS
SVS-NSSVAPA-------------------------------------------------
--------------------------------------------
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
------------------------------------------------------------
----------MA-AWEAA-FAARRRHE-EEDTTRD--SVFTYTNSNN-TRGPFEGPNY--
------HIAPRWVYNLTSVWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVAD
LGETVIA-STISVINQIS-GYFI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVV
CKPFGN-IKFDGKLAVAGILFSWLWSCAW-TAPPIFG-WSRYWPHGLKTSCGPDVFSGSS
DPGVQSYMVVLMVTCCFFPLAIIILCYLQVWLAI----RAVAAQQK--------------
------------------------------------------------------------
------------------------------------------------------------
--------ESESTQKAEKEVSRMVVVMIVAYCFCWGPYTFFACFAAANPGY---AFHPLA
AALPAYFAKSATIYNPIIYVFMNRQFRNCILQLF------GKKVDDG-SEVST-SRTEVS
SVS-NSSVSPA-------------------------------------------------
--------------------------------------------
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
------------------------------------------------------------
---------------------MSSNSSQAPPNGTP---------------GPFDGPQWP-
------YQAPQSTYVGVAVLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVAD
LLVTLCG-SSVSLSNNIN-GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVV
CKPLGD-FQFQRRHAVSGCAFTWGWALLW-SAPPLLG-WSSYVPEGLRTSCGPNWYT--G
GSNNNSYILSLFVTCFVLPLSLILFSYTNLLLTL----RAAAAQQK--------------
------------------------------------------------------------
------------------------------------------------------------
--------EADTTQRAEREVTRMVIVMVMAFLLCWLPYSTFALVVATHKGI---IIQPVL
ASLPSYFSKTATVYNPIIYVFMNKQFQSCLLEMLCCG-YQPQRTGKA-SPGTPGPHADVT
AAGLRNKVMPA-------------------------------------------------
-----------HPV------------------------------
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
------------------------------------------------------------
----MESGNVSSSLFGNVSTALRPEARLSA-------ETRLLGWNVPPEELRHIPEHWLT
-----YPEPPESMNYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCD
FMMMVK--TPIFIYNSFH-QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVI
TRPMEG--KMTHGKAIAMIIFIYMYATPW-VVACYTETWGRFVPEGYLTSCTFDYLT--D
NFDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKKMNVESLRS-----
------------------------------------------------------------
------------------------------------------------------------
-------NVDKNKETAEIRIAKAAITICFLFFCSWTPYGVMSLIGAFGDKT---LLTPGA
TMIPACACKMVACIDPFVYAISHPRYRMELQKRCPWL-----ALNEK-APESSAVASTST
TQE-PQQTTAA-------------------------------------------------
--------------------------------------------
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
------------------------------------------------------------
----MEYHN-VSSVLGNVSSVLRPDARLSA-------ESRLLGWNVPPDELRHIPEHWLI
-----YPEPPESMNYLLGTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCD
FMMMIK--TPIFIYNSFH-QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVI
TRPMEG--KMTHGKAIAMIIFIYLYATPW-VVACYTESWGRFVPEGYLTSCTFDYLT--D
NFDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKKMNVDSLRS-----
------------------------------------------------------------
------------------------------------------------------------
-------NVDKSKEAAEIRIAKAAITICFLFFASWTPYGVMSLIGAFGDKT---LLTPGA
TMIPACTCKMVACIDPFVYAISHPRYRMELQKRCPWL-----AISEK-APESRAAISTST
TQE-QQQTTAA-------------------------------------------------
--------------------------------------------
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
------------------------------------------------------------
----------MEPLCNASEPPLRPEAR-SSGNG----DLQFLGWNVPPDQIQYIPEHWLT
-----QLEPPASMHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFD
LIMCLK--APIF--NSFH-RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVI
TKPMNR--NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFWDRFVPEGYLTSCSFDYLS--D
NFDTRLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKKMNVESLRS-----
------------------------------------------------------------
------------------------------------------------------------
-------NVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKS---LLTQGA
TMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWL-----GVNEK-SGEISSAQSTTT
QEQ--QQTTAA-------------------------------------------------
--------------------------------------------
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
------------------------------------------------------------
----------MDALCNASEPPLRPEARMSSGSD----ELQFLGWNVPPDQIQYIPEHWLT
-----QLEPPASMHYMLGVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFD
LIMCLK--APIFIYNSFH-RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVI
TKPMNR--NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFWDRFVPEGYLTSCSFDYLS--D
NFDTRLFVGTIFLFSFVVPTLMILYYYSQIVGHVFNHEKALREQAKKMNVESLRS-----
------------------------------------------------------------
------------------------------------------------------------
-------NVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKS---LLTPGA
TMIPACTCKLVACIEPFVYAISHPRYRMELQKRCPWL-----GVNEK-SGEASSAQSTTT
QEQ-TQQTSAA-------------------------------------------------
--------------------------------------------
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
------------------------------------------------------------
-------------MTNATGPQMAYYGAASMDFGYP--EGVSIVDFVRPEIKPYVHQHWYN
-----YPPVNPMWHYLLGVIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSD
LIMLTTN-VPFFTYNCFSGGVWM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNII
CNGFNG-PKLTTGKAVVFALISWVIAIGC-ALPPFFG-WGNYILEGILDSCSYDYLT--Q
DFNTFSYNIFIFVFDYFLPAAIIVFSYVFIVKAIFAHEAAMRAQAKKMNVSTLRS-----
------------------------------------------------------------
------------------------------------------------------------
--------NEADAQRAEIRIAKTALVNVSLWFICWTPYALISLKGVMGDTS---GITPLV
STLPALLAKSCSCYNPFVYAISHPKYRLAITQHLPWF--CVHETETK-SNDDSQSNSTVA
QDK-A-------------------------------------------------------
--------------------------------------------
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
------------------------------------------------------------
-------------MANVTGPQMAFYGSGAATFGYP--EGMTVADFVPDRVKHMVLDHWYN
-----YPPVNPMWHYLLGVVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSD
LIMLTTN-FPPFCYNCFSGGRWM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNII
CNGFNG-PKLTQGKATFMCGLAWVISVGW-SLPPFFG-WGSYTLEGILDSCSYDYFT--R
DMNTITYNICIFIFDFFLPASVIVFSYVFIVKAIFAHEAAMRAQAKKMNVTNLRS-----
------------------------------------------------------------
------------------------------------------------------------
--------NEAETQRAEIRIAKTALVNVSLWFICWTPYAAITIQGLLGNAE---GITPLL
TTLPALLAKSCSCYNPFVYAISHPKFRLAITQHLPWF--CVHEKDPN-DVEENQSSNTQT
QEK-S-------------------------------------------------------
--------------------------------------------
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
------------------------------------------------------------
-------MESFAVAAAQLGPHFAPLS------------NGSVVDKVTPDMAHLISPYWNQ
-----FPAMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISD
FGIMITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVI
VKGMAG-RPMTIPLALGKM----------------------YVPEGNLTSCGIDYLE--R
DWNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLRS-----
------------------------------------------------------------
------------------------------------------------------------
--------SEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLFKF-E---GLTPLN
TIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCC--VFGKVDDG-KSSDAQSQA-TA
SEA-ESKA----------------------------------------------------
--------------------------------------------
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
------------------------------------------------------------
-------MESFAVAAAQLGPHFAPLS------------NGSVVDKVTPDMAHLISPYWNQ
-----FPAMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISD
FGIMITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVI
VKGMAG-RPMTIPLALGKIAYIWFMSSIW-CLAPAFG-WSRYVPEGNLTSCGIDYLE--R
DWNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLRS-----
------------------------------------------------------------
------------------------------------------------------------
--------SEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLFKF-E---GLTPLN
TIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCC--VFGKVDDG-KSSDAQSQA-TA
SEA-ESKA----------------------------------------------------
--------------------------------------------
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
------------------------------------------------------------
-------MDSFAAVATQLGPQFAAPS------------NGSVVDKVTPDMAHLISPYWDQ
-----FPAMDPIWAKILTAYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISD
FGIMITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVI
VKGMAG-RPMTIPLALGKIAYIWFMSTIWCCLAPVFG-WSRYVPEGNLTSCGIDYLE--R
DWNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLRS-----
------------------------------------------------------------
------------------------------------------------------------
--------SEDADKSAEGKLAKVALVTISLWFMAWTPYLVINCMGLFKF-E---GLTPLN
TIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCC--VFGKVDDG-KSSEAQSQA-TT
SEA-ESKA----------------------------------------------------
--------------------------------------------
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
------------------------------------------------------------
--MERSHLPETPFDLAHSGPRFQAQSSG----------NGSVLDNVLPDMAHLVNPYWSR
-----FAPMDPMMSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSD
FCMMASQ-SPVMIINFYY-ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVI
VKGING-TPMTIKTSIMKILFIWMMAVFW-TVMPLIG-WSAYVPEGNLTACSIDYMT--R
MWNPRSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKKMNVKSLRS-----
------------------------------------------------------------
------------------------------------------------------------
--------SEDCDKSAEGKLAKVALTTISLWFMAWTPYLVICYFGLFKI-D---GLTPLT
TIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMC--VFGNTDEP-KPDAPASDTETT
SEA-DSKA----------------------------------------------------
--------------------------------------------
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
------------------------------------------------------------
--MERSLLPEPPLAMALLGPRFEAQTGG----------NRSVLDNVLPDMAPLVNPHWSR
-----FAPMDPTMSKILGLFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSD
FCMMASQ-SPVMIINFYY-ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVI
VKGING-TPMTIKTSIMKIAFIWMMAVFW-TIMPLIG-WSSYVPEGNLTACSIDYMT--R
QWNPRSYLITYSLFVYYTPLFMICYSYWFIIATVAAHEKAMRDQAKKMNVKSLRS-----
------------------------------------------------------------
------------------------------------------------------------
--------SEDCDKSAENKLAKVALTTISLWFMAWTPYLIICYFGLFKI-D---GLTPLT
TIWGATFAKTSAVYNPIVYGISHPNDRLVLKEKCPMC--VCGTTDEP-KPDAPPSDTETT
SEA-ESKD----------------------------------------------------
--------------------------------------------
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
------------------------------------------------------------
-------------MIAVSGPSYEAFSYGGQARF----NNQTVVDKVPPDMLHLIDANWYQ
-----YPPLNPMWHGILGFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISN
FLMMFCM-SPPMVINCYY-ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVI
VKGLSG-KPLSINGALIRIIAIWLFSLGW-TIAPMFG-WNRYVPEGNMTACGTDYFN--R
GLLSASYLVCYGIWVYFVPLFLIIYSYWFIIQAVAAHEKNMREQAKKMNVASLRS-----
------------------------------------------------------------
------------------------------------------------------------
--------SENQNTSAECKLAKVALMTISLWFMAWTPYLVINFSGIFNL-V---KISPLF
TIWGSLFAKANAVYNPIVYGISHPKYRAALFAKFPSL--AC-AAEPS-SDAVSTTSGTTT
VTD-NEKSNA--------------------------------------------------
--------------------------------------------
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
------------------------------------------------------------
---------------MANQLSYSSLGWPYQP-------NASVVDTMPKEMLYMIHEHWYA
-----FPPMNPLWYSILGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSD
FCMMAFM-MPTMTSNCFA-ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVI
VRGMAA-APLTHKKATLLLLFVWIWSGGW-TILPFFG-WSRYVPEGNLTSCTVDYLT--K
DWSSASYVVIYGLAVYFLPLITMIYCYFFIVHAVAEHEKQLREQAKKMNVASLRA-----
------------------------------------------------------------
------------------------------------------------------------
-------NADQQKQSAECRLAKVAMMTVGLWFMAWTPYLIISWAGVFSSGT---RLTPLA
TIWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPSL--ACGSGESG-SDVKSEASATTT
MEE-KPKIPEA-------------------------------------------------
--------------------------------------------
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
------------------------------------------------------------
--------------------MVESTTLVNQTWWY----NPTVD----------IHPHWAK
-----FDPIPDAVYYSVGIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSD
LSFSAINGFPLKTISAFM-KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVI
GRPMAASKKMSHRRAFLMIIFVWMWSIVW-SVGPVFN-WGAYVPEGILTSCSFDYLS--T
DPSTRSFILCMYFCGFMLPIIIIAFCYFNIVMSVSNHEKEMAAMAKRLNAKELR------
------------------------------------------------------------
------------------------------------------------------------
--------KAQAGASAEMKLAKISMVIITQFMLSWSPYAIIALLAQFGPAE---WVTPYA
AELPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCCQFDEKE-CEDANDAEEEVV
ASE-R--GGESRDAAQMKEMMAMMQKMQAQQAAYQPPPPPQGY--PPQGYPPQGAYPPPQ
GYPPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVDNQAYQA
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
------------------------------------------------------------
---------------------MGRDLRDNETWWY----NPSIV----------VHPHWRE
-----FDQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSD
FTFSLVNGFPLMTISCFL-KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVI
GRPMAASKKMSHRRAFIMIIFVWLWSVLW-AIGPIFG-WGAYTLEGVLCNCSFDYIS--R
DSTTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKRLNAKELR------
------------------------------------------------------------
------------------------------------------------------------
--------KAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLE---WVTPYA
AQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKE-TEDDKDAETEIP
AGE-SSDAAPSADAAQMKEMMAMMQKMQQQQAAY----PPQGYAPPPQGYPPQGY--PPQ
GYPPQGYPPQGYPP---PPQGAPPQ-GAPPAAPPQGVDNQAYQA
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
M---------MDV-NSSGRPDLYGHLRSFLLPEVGRGLPDLSP-----------------
--DGGADPVAGSWAPHLLS---EVTASPAPTWDAPPDNASGCGEQI----------NY--
---------GRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALAD
LSVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGI
TRPLTYPVRQNGKCMAKMILSVWLLSASI-TLPPLFG-WAQ--------NVNDDKV--CL
ISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAA----RKSAAKHKFPGFPRVE------
-------------------------PDSVI---ALNGIVKLQK-------------EVEE
CAN--------------------------------------------LSRLLKH------
------ERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWV
ERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINR-----KLSAAGMHEALK
LAE-RPERPEF----------------VLQNADYCRK-----------------------
---------KGHDS------------------------------
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
------------------------------------------------------------
-------------MPHLLSGFLEVTASPAPTWDAPPDNVSGCGEQI----------NY--
---------GRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALAD
LSVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGI
TRPLTYPVRQNGKCMAKMILSVWLLSASI-TLPPLFG-WAQ--------NVNDDKV--CL
ISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAA----RKSAAKHKFPGFPRVQ------
-------------------------PESVI---SLNGVVKLQK-------------EVEE
CAN--------------------------------------------LSRLLKH------
------ERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWV
ERTCLWLGYANSLINPFIYAFFNRDLRPTSRSLLQCQYRNINR-----KLSAAGMHEALK
LAE-RPERSEF----------------VLQNSDHCGK-----------------------
---------KGHDT------------------------------
>    31=p A47425 serotonin receptor 5HT-7 - rat
------------------------------------------------------------
-------------MPHLLSGFLEVTASPAPTWDAPPDNVSGCGEQI----------NY--
---------GRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALAD
LSVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGI
TRPLTYPVRQNGKCMAKMILSVWLLSASI-TLPPLFG-WAQ--------NVNDDKV--CL
ISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAA----RKSAAKHKFPGFPRVQ------
-------------------------PESVI---SLNGVVKLQK-------------EVEE
CAN--------------------------------------------LSRLLKH------
------ERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWV
ERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINR-----KLSAAGMHEALK
LAE-RPERSEF----------------VLQNSDHCGK-----------------------
---------KGHDT------------------------------
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
------------------------------------------------------------
----------MD---VLSPGQGNNTTSPPAPFETG-GNTTGISDVT-----------V--
-----------SYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTD
LMVSVLV-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAI
TDPIDYVNKRTPRRAAALISLTWLIGFLI-SIPPMLG-WRT--PE---DRSDPD---ACT
ISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT---RHGAS
P-----------------------APQP---KKSVNGESGSRNWRLGVESKAGGA----L
CANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCA--PASFERK---------
-NERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSC--HMPTLL
GAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC---------------------
----RQ------------------------------------------------------
--------------------------------------------
>    33=p A35181 serotonin receptor class 1A - rat
------------------------------------------------------------
----------MD---VFSFGQGNNTTASQEPFGTG-GNVTSISDVT-----------F--
-----------SYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTD
LMVSVLV-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAI
TDPIDYVNKRTPRRAAALISLTWLIGFLI-SIPPMLG-WRT--PE---DRSDPD---ACT
ISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVRKVEKKGAGT---SLGTS
S-----------------------APPP---KKSLNGQPGSGDWRRCAENRAVGT----P
CTNGAVRQGDDEATLEVIEVHRVGNSKEHLPLPSESGSNSYA--PACLERK---------
-NERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSC--HMPALL
GAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC---------------------
----RR------------------------------------------------------
--------------------------------------------
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
MANFTFGDLALDVARMGGLASTPSGLRS-----TGLTTPGLSPTGLVTSDFNDSYGLTGQ
FINGSHSSRSRD-----------NASANDT-------SATNMTDDR-----------YWS
-----LTVYSHEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVAD
LMVAVLV-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAV
TS-IDYIRRRSARRILLMIMVVWIVALFI-SIPPLFG-WRD--P-----NNDPDKTGTCI
ISQDKGYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVAS
PKTEYSVVSDCNG---------CNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPE
NANGVNSNSSSSERLKQIQI-------ETAEAFANGCAEEAS--IAMLERQCNNGKKISS
NDTPYSRTREKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPFVDPE---GIPPFA
RSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYR---------------------
----RGHR----------------------------------------------------
--------------------------------------------
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
MANFTFGDLALDVARMGGLASTPSGLRS-----TGLTTPGLSPTGLVTSDFNDSYGLTGQ
FINGSHSSRSRD-----------NASANDT-------SATNMTDDR-----------YWS
-----LTVYSHEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVAD
LMVAVLV-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAV
TS-IDYIRRRSARRILLMIMVVWIVALFI-SIPPLFG-WRD--P-----NNDPDKTGTCI
ISQDKGYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVAS
PKTEYSVVSDCNG---------CNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPE
NANGVNSNSSSSERLKQIQI-------ETAEAFANGCAEEAS--IAMLERQCNNGKKISS
NDTPYSRTREKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPFVDPE---GIPPFA
RSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYR---------------------
----RGHR----------------------------------------------------
--------------------------------------------
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
M-----------------------------------------------------------
--EGAEGQEELDWEALYLRLPLQNCSWNSTGWEPN-WNVTVVPNTT-----------WWQ
ASAPFDTPAALVRAAAKAVVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVAD
LLVACLV-MPLGAVYEVV-QRWT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAV
TN-IDYIHASTAKRVGMMIACVWTVSFFV-CIAQLLG-WKD--PDWN-QRVSEDLR--CV
VSQDVGYQIFATASSFYVPVLIILILYWRIYQTARKRIRRRRGATARGGVGPPPVPAGGA
L-----VAGGGSGGIAAAVVAVIGRPLPTISETTTTGFTNVSSNNTSPEKQ--------S
CANGL----------------------EADPPTTGYGAVAAAYYPSLVRRK---------
-------PKEAADSKRERKAAKTLAIITGAFVACWLPFFVLAILVPTCDCE----VSPVL
TSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRLLCGRRV---------------------
----RRRRAPQ-------------------------------------------------
--------------------------------------------
