>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
--------------MNGTEG--------------------DNFY----------------
--------VP--FSNKTGLARSPYEYPQYYL-----AEPWK-------------------
------------------------------------YSAL---AAYMFFLILVGFPVNFL
TLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-FTVTMYTSMN-GYFV--FGPTMCSIE
GFFATLGGEVALWSLVVLAIERYIVICKPMGN-FRFGNTHAIMGVAFTWIMALAC-AAPP
LV-GW-----SRYIPEGMQCSCGPDYYTLNPNFNNESYVVYMFVVHFLVPFVIIFFCYGR
LLCTV----KEAAAAQQ-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------ESASTQK-----AEKEVTRMVVLMVIGFLVCWVPYASV-AFYIFT---
HQGSDFGATFMTLPAFFAKSSALYNPVIYILMNKQFRNCMITTLC----CGK----NPLG
DDE--SGA-----------STSKTEVSSVSTS----------------------------
--------------------------------------PVSPA----------
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
--------------MNGTEG--------------------PNFY----------------
--------VP--FSNITGVVRSPFEQPQYYL-----AEPWQ-------------------
------------------------------------FSML---AAYMFLLIVLGFPINFL
TLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTTLYTSLH-GYFV--FGPTGCNLE
GFFATLGGEIGLWSLVVLAIERYVVVCKPMSN-FRFGENHAIMGVAFTWVMALAC-AAPP
LV-GW-----SRYIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIVIFFCYGQ
LVFTV----KEAAAQQQ-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------ESATTQK-----AEKEVTRMVIIMVIFFLICWLPYASV-AMYIFT---
HQGSNFGPIFMTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSLC----CGK----NPLG
DDE--ASA-----------TASKTE-----TS----------------------------
--------------------------------------QVAPA----------
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
--------------MNGTEG--------------------INFY----------------
--------VP--MSNKTGVVRSPFEYPQYYL-----AEPWK-------------------
------------------------------------YRLV---CCYIFFLISTGLPINLL
TLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-FTVTFYTAWN-GYFV--FGPVGCAVE
GFFATLGGQVALWSLVVLAIERYIVVCKPMGN-FRFSATHAMMGIAFTWVMAFSC-AAPP
LF-GW-----SRYMPEGMQCSCGPDYYTHNPDYHNESYVLYMFVIHFIIPVVVIFFSYGR
LICKV----REAAAQQQ-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------ESATTQK-----AEKEVTRMVILMVLGFMLAWTPYAVV-AFWIFT---
NKGADFTATLMAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTIC----CGK----NPFG
DEDVSSTV-----------SQSKTEVSSVSSS----------------------------
--------------------------------------QVSPA----------
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
--------------MNGTEG--------------------KNFY----------------
--------VP--MSNRTGLVRSPFEYPQYYL-----AEPWQ-------------------
------------------------------------FKIL---ALYLFFLMSMGLPINGL
TLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-FTVTFYTAIN-GYFV--LGPTGCAVE
GFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSSSHAFAGIAFTWVMALAC-AAPP
LF-GW-----SRYIPEGMQCSCGPDYYTLNPDYNNESYVIYMFVCHFILPVAVIFFTYGR
LVCTV----KAAAAQQQ-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------DSASTQK-----AEREVTKMVILMVFGFLIAWTPYATV-AAWIFF---
NKGADFSAKFMAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTIF----CGK----NPLG
DDE-SSTV-----------STSKTEVSS--------------------------------
---------------------------------------VSPA----------
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
--------------MNGTEG--------------------NNFY----------------
--------VP--LSNRTGLVRSPFEYPQYYL-----AEPWQ-------------------
------------------------------------FKLL---AVYMFFLICLGLPINGL
TLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-FTVTFYTAIN-GYFA--LGPTGCAVE
GFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSSTHASAGIAFTWVMAMAC-AAPP
LV-GW-----SRYIPEGIQCSCGPDYYTLNPEYNNESYVLYMFICHFILPVTIIFFTYGR
LVCTV----KAAAAQQQ-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------DSASTQK-----AEREVTKMVILMVLGFLVAWTPYATV-AAWIFF---
NKGAAFSAQFMAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTLF----CGK----NPLG
DEE-SSTV-----------STSKTEVSS--------------------------------
---------------------------------------VSPA----------
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
--------------MKQVPEF------------------HEDFYIP--------------
--------IP--LDINNLSAYSPFLVPQDHL-----GNQGI-------------------
------------------------------------FMAM---SVFMFFIFIGGASINIL
TILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-SPLSFYSFFN-RYFI--FGATACKIE
GFLATLGGMVGLWSLAVVAFERWLVICKPLGN-FTFKTPHAIAGCILPWISALAA-SLPP
LF-GW-----SRYIPEGLQCSCGPDWYTTNNKYNNESYVMFLFCFCFAVPFGTIVFCYGQ
LLITL----KLAAKAQA-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------DSASTQK-----AEREVTKMVVVMVLGFLVCWAPYASF-SLWIVS---
HRGEEFDLRMATIPSCLSKASTVYNPVIYVLMNKQFRSCMMKMV-----CGK----N-IE
EDE--AST-----------SSQVTQVSS--------------------------------
---------------------------------------VAPEK---------
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
--------------MRKMSE--------------------EEFYL---------------
--------------FKNISSVGPWDGPQYHI-----APVWA-------------------
------------------------------------FYLQ---AAFMGTVFLIGFPLNAM
VLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-VFPVFVASCN-GYFV--FGRHVCALE
GFLGTVAGLVTGWSLAFLAFERYIVICKPFGN-FRFSSKHALTVVLATWTIGIGV-SIPP
FF-GW-----SRFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLICFSYTQ
LLRAL----KAVAAQQQ-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------ESATTQK-----AEREVSRMVVVMVGSFCVCYVPYAAF-AMYMVN---
NRNHGLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIMKMV-----CGK----A-MT
DES--DTC-----------SSQKTEVSTVSST----------------------------
--------------------------------------QVGPN----------
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------DLAETVIA-STISIVNQVS-GYFV--LGHPMCVLE
GYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDAKLAIVGIAFSWIWAAVW-TAPP
IF-GW-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQ
VWLAI----RAVAKQQK-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------ESESTQK-----AEKEVTRMVVVMVLAFC-------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
--------------MAQQWSLQRLAG-RHPQDSYEDSTQSSIFTY---------------
--------------TNSNSTRGPFEGPNYHI-----APRWV-------------------
------------------------------------YHLT---SVWMIFVVIASVFTNGL
VLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISVVNQVY-GYFV--LGHPMCVLE
GYTVSLCGITGLWSLAIISWERWMVVCKPFGN-VRFDAKLAIVGIAFSWIWAAVW-TAPP
IF-GW-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQ
VWLAI----RAVAKQQK-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------ESESTQK-----AEKEVTRMVVVMVLAFCFCWGPYAFF-ACFAAA---
NPGYPFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLF------------GKKV
DDG-SELS-----------SASKTEVSSV--S----------------------------
--------------------------------------SVSPA----------
>    10== Z68193   1 human Red Opsin <>[]
--------------MAQQWSLQRLAG-RHPQDSYEDSTQSSIFTY---------------
--------------TNSNSTRGPFEGPNYHI-----APRWV-------------------
------------------------------------YHLT---SVWMIFVVTASVFTNGL
VLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISIVNQVS-GYFV--LGHPMCVLE
GYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDAKLAIVGIAFSWIWSAVW-TAPP
IF-GW-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQ
VWLAI----RAVAKQQK-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------ESESTQK-----AEKEVTRMVVVMIFAYCVCWGPYTFF-ACFAAA---
NPGYAFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLF------------GKKV
DDG-SELS-----------SASKTEVSSV--S----------------------------
--------------------------------------SVSPA----------
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
--------------MTEAWNVAVFAARRSRDD--DDTTRGSVFTY---------------
--------------TNTNNTRGPFEGPNYHI-----APRWV-------------------
------------------------------------YNLV---SFFMIIVVIASCFTNGL
VLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-STISVFNQIF-GYFI--LGHPLCVIE
GYVVSSCGITGLWSLAIISWERWFVVCKPFGN-IKFDSKLAIIGIVFSWVWAWGW-SAPP
IF-GW-----SRYWPHGLKTSCGPDVFSGSVELGCQSFMLTLMITCCFLPLFIIIVCYLQ
VWMAI----RAVAAQQK-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------ESESTQK-----AEREVSRMVVVMIVAFCICWGPYASF-VSFAAA---
NPGYAFHPLAAALPAYFAKSATIYNPVIYVFMNRQFRNCIMQLF------------GKKV
DDG-SEAS-----------TTSRTEVSSVSNS----------------------------
--------------------------------------SVAPA----------
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
---------------MAAWEAAFAARRRHEE---EDTTRDSVFTY---------------
--------------TNSNNTRGPFEGPNYHI-----APRWV-------------------
------------------------------------YNLT---SVWMIFVVAASVFTNGL
VLVATWKFKKLRHPLNWILVNLAVADLGETVIA-STISVINQIS-GYFI--LGHPMCVVE
GYTVSACGITALWSLAIISWERWFVVCKPFGN-IKFDGKLAVAGILFSWLWSCAW-TAPP
IF-GW-----SRYWPHGLKTSCGPDVFSGSSDPGVQSYMVVLMVTCCFFPLAIIILCYLQ
VWLAI----RAVAAQQK-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------ESESTQK-----AEKEVSRMVVVMIVAYCFCWGPYTFF-ACFAAA---
NPGYAFHPLAAALPAYFAKSATIYNPIIYVFMNRQFRNCILQLF------------GKKV
DDG-SEVS-----------T-SRTEVSSVSNS----------------------------
--------------------------------------SVSPA----------
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
--------------------------------------MSSNSSQ---------------
--------------APPNGTPGPFDGPQWPYQ----APQST-------------------
------------------------------------YVGV---AVLMGTVVACASVVNGL
VIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-SSVSLSNNIN-GFFV--FGRRMCELE
GFMVSLTGIVGLWSLAILALERYVVVCKPLGD-FQFQRRHAVSGCAFTWGWALLW-SAPP
LL-GW-----SSYVPEGLRTSCGPNWYTGGS--NNNSYILSLFVTCFVLPLSLILFSYTN
LLLTL----RAAAAQQK-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------EADTTQR-----AEREVTRMVIVMVMAFLLCWLPYSTF-ALVVAT---
HKGIIIQPVLASLPSYFSKTATVYNPIIYVFMNKQFQSCLLEMLC----CGYQPQRTGKA
SPG-TPGP-----------HADVTAAGLR--N----------------------------
--------------------------------------KVMPAHPV-------
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
-----MESGNVSSSLFGNVSTALRPEARLSA-------ETRLLGW---------------
----------------------NVPPEELRHI----PEHWLTYPEPP-------------
---------------------------------ESMNYLL---GTLYIFFTLMSMLGNGL
VIWVFSAAKSLRTPSNILVINLAFCDFMMMVKT--PIFIYNSFH-QGYA--LGHLGCQIF
GIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--KMTHGKAIAMIIFIYMYATPW-VVAC
YTETW-----GRFVPEGYLTSCTFDYLTDN--FDTRLFVACIFFFSFVCPTTMITYYYSQ
IVGHVFSHEKALRDQAKK------------------------------------------
----------------------------------------------MNVESLRS------
------------------------------------------------------------
-----------NVDKNKET-----AEIRIAKAAITICFLFFCSWTPYGVM-SLIGAF---
GDKTLLTPGATMIPACACKMVACIDPFVYAISHPRYRMELQKRCPWLALN------EKAP
ESSAVAST-----------STTQEP-QQTTAA----------------------------
-----------------------------------------------------
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
-----MEYHNVSSVL-GNVSSVLRPDARLSA-------ESRLLGW---------------
----------------------NVPPDELRHI----PEHWLIYPEPP-------------
---------------------------------ESMNYLL---GTLYIFFTVISMIGNGL
VMWVFSAAKSLRTPSNILVINLAFCDFMMMIKT--PIFIYNSFH-QGYA--LGHLGCQIF
GVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--KMTHGKAIAMIIFIYLYATPW-VVAC
YTESW-----GRFVPEGYLTSCTFDYLTDN--FDTRLFVACIFFFSFVCPTTMITYYYSQ
IVGHVFSHEKALRDQAKK------------------------------------------
----------------------------------------------MNVDSLRS------
------------------------------------------------------------
-----------NVDKSKEA-----AEIRIAKAAITICFLFFASWTPYGVM-SLIGAF---
GDKTLLTPGATMIPACTCKMVACIDPFVYAISHPRYRMELQKRCPWLAIS------EKAP
ESRAAIST-----------STTQEQ-QQTTAA----------------------------
-----------------------------------------------------
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
-----ME------PLCNASEPPLRPEAR-SSGN----GDLQFLGW---------------
----------------------NVPPDQIQYI----PEHWLTQLEPP-------------
---------------------------------ASMHYML---GVFYIFLFCASTVGNGM
VIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLKA--PIF--NSFH-RGFAIYLGNTWCQIF
ASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNIIIWLYCTPW-VVLP
LTQFW-----DRFVPEGYLTSCSFDYLSDN--FDTRLFVGTIFFFSFVCPTLMILYYYSQ
IVGHVFSHEKALREQAKK------------------------------------------
----------------------------------------------MNVESLRS------
------------------------------------------------------------
-----------NVDKSKET-----AEIRIAKAAITICFLFFVSWTPYGVM-SLIGAF---
GDKSLLTQGATMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWLGVN------EKSG
EISSAQST------------TTQEQ-QQTTAA----------------------------
-----------------------------------------------------
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
-----MD------ALCNASEPPLRPEARMSSGS----DELQFLGW---------------
----------------------NVPPDQIQYI----PEHWLTQLEPP-------------
---------------------------------ASMHYML---GVFYIFLFFASTLGNGM
VIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLKA--PIFIYNSFH-RGFA--LGNTWCQIF
ASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNIIIWLYCTPW-VVLP
LTQFW-----DRFVPEGYLTSCSFDYLSDN--FDTRLFVGTIFLFSFVVPTLMILYYYSQ
IVGHVFNHEKALREQAKK------------------------------------------
----------------------------------------------MNVESLRS------
------------------------------------------------------------
-----------NVDKSKET-----AEIRIAKAAITICFLFFVSWTPYGVM-SLIGAF---
GDKSLLTPGATMIPACTCKLVACIEPFVYAISHPRYRMELQKRCPWLGVN------EKSG
EASSAQST------------TTQEQTQQTSAA----------------------------
-----------------------------------------------------
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
--------------MTNATGPQMAYYGAASMD----------FGY---------------
--------------PEGVSIVDFVRPEIKPYV----HQHWYNYPPVN-------------
---------------------------------PMWHYLL---GVIYLFLGTVSIFGNGL
VIYLFNKSAALRTPANILVVNLALSDLIMLTTN-VPFFTYNCFSGGVWM--FSPQYCEIY
ACLGAITGVCSIWLLCMISFDRYNIICNGFNG-PKLTTGKAVVFALISWVIAIGC-ALPP
FF-GW-----GNYILEGILDSCSYDYLTQD--FNTFSYNIFIFVFDYFLPAAIIVFSYVF
IVKAIFAHEAAMRAQAKK------------------------------------------
----------------------------------------------MNVSTLRS------
------------------------------------------------------------
------------NEADAQR-----AEIRIAKTALVNVSLWFICWTPYALI-SLKGVM---
GDTSGITPLVSTLPALLAKSCSCYNPFVYAISHPKYRLAITQHLPWFCV--------HET
ETKSNDDS---------QSNSTVAQDKA--------------------------------
-----------------------------------------------------
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
--------------MANVTGPQMAFYGSGAAT----------FGY---------------
--------------PEGMTVADFVPDRVKHMV----LDHWYNYPPVN-------------
---------------------------------PMWHYLL---GVVYLFLGVISIAGNGL
VIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-FPPFCYNCFSGGRWM--FSGTYCEIY
AALGAITGVCSIWTLCMISFDRYNIICNGFNG-PKLTQGKATFMCGLAWVISVGW-SLPP
FF-GW-----GSYTLEGILDSCSYDYFTRD--MNTITYNICIFIFDFFLPASVIVFSYVF
IVKAIFAHEAAMRAQAKK------------------------------------------
----------------------------------------------MNVTNLRS------
------------------------------------------------------------
------------NEAETQR-----AEIRIAKTALVNVSLWFICWTPYAAI-TIQGLL---
GNAEGITPLLTTLPALLAKSCSCYNPFVYAISHPKFRLAITQHLPWFCV--------HEK
DPNDVEEN---------QSSNTQTQEKS--------------------------------
-----------------------------------------------------
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
-----ME---SFAVAAAQLGPHFAPLS---------------------------------
----------------NGSVVDKVTPDMAHLI----SPYWNQFPAMD-------------
---------------------------------PIWAKIL---TAYMIMIGMISWCGNGV
VIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV--LGPMMCDIY
AGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKM---------------
------------YVPEGNLTSCGIDYLERD--WNPRSYLIFYSIFVYYIPLFLICYSYWF
IIAAVSAHEKAMREQAKK------------------------------------------
----------------------------------------------MNVKSLRS------
------------------------------------------------------------
------------SEDAEKS-----AEGKLAKVALVTITLWFMAWTPYLVINCM-GLF---
-KFEGLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCP-CCVFGKVD------
DGKSSDAQS--------QATASEAESKA--------------------------------
-----------------------------------------------------
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
-----ME---SFAVAAAQLGPHFAPLS---------------------------------
----------------NGSVVDKVTPDMAHLI----SPYWNQFPAMD-------------
---------------------------------PIWAKIL---TAYMIMIGMISWCGNGV
VIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV--LGPMMCDIY
AGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKIAYIWFMSSIW-CLAP
AF-GW-----SRYVPEGNLTSCGIDYLERD--WNPRSYLIFYSIFVYYIPLFLICYSYWF
IIAAVSAHEKAMREQAKK------------------------------------------
----------------------------------------------MNVKSLRS------
------------------------------------------------------------
------------SEDAEKS-----AEGKLAKVALVTITLWFMAWTPYLVINCM-GLF---
-KFEGLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCP-CCVFGKVD------
DGKSSDAQS--------QATASEAESKA--------------------------------
-----------------------------------------------------
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
-----MD---SFAAVATQLGPQFAAPS---------------------------------
----------------NGSVVDKVTPDMAHLI----SPYWDQFPAMD-------------
---------------------------------PIWAKIL---TAYMIIIGMISWCGNGV
VIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV--LGPMMCDIY
AGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKIAYIWFMSTIWCCLAP
VF-GW-----SRYVPEGNLTSCGIDYLERD--WNPRSYLIFYSIFVYYIPLFLICYSYWF
IIAAVSAHEKAMREQAKK------------------------------------------
----------------------------------------------MNVKSLRS------
------------------------------------------------------------
------------SEDADKS-----AEGKLAKVALVTISLWFMAWTPYLVINCM-GLF---
-KFEGLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCP-CCVFGKVD------
DGKSSEAQS--------QATTSEAESKA--------------------------------
-----------------------------------------------------
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
MERSHLP---ETPFDLAHSGPRFQAQSSG-------------------------------
----------------NGSVLDNVLPDMAHLV----NPYWSRFAPMD-------------
---------------------------------PMMSKIL---GLFTLAIMIISCCGNGV
VVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ETWV--LGPLWCDIY
AGCGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIKTSIMKILFIWMMAVFW-TVMP
LI-GW-----SAYVPEGNLTACSIDYMTRM--WNPRSYLITYSLFVYYTPLFLICYSYWF
IIAAVAAHEKAMREQAKK------------------------------------------
----------------------------------------------MNVKSLRS------
------------------------------------------------------------
------------SEDCDKS-----AEGKLAKVALTTISLWFMAWTPYLVI-CYFGLF---
-KIDGLTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCP-MCVFGNTD--EPKP
DAPASDTE-----------TTSEADSKA--------------------------------
-----------------------------------------------------
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
MERSLLP---EPPLAMALLGPRFEAQTGG-------------------------------
----------------NRSVLDNVLPDMAPLV----NPHWSRFAPMD-------------
---------------------------------PTMSKIL---GLFTLVILIISCCGNGV
VVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ETWV--LGPLWCDIY
AACGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIKTSIMKIAFIWMMAVFW-TIMP
LI-GW-----SSYVPEGNLTACSIDYMTRQ--WNPRSYLITYSLFVYYTPLFMICYSYWF
IIATVAAHEKAMRDQAKK------------------------------------------
----------------------------------------------MNVKSLRS------
------------------------------------------------------------
------------SEDCDKS-----AENKLAKVALTTISLWFMAWTPYLII-CYFGLF---
-KIDGLTPLTTIWGATFAKTSAVYNPIVYGISHPNDRLVLKEKCP-MCVCGTTD--EPKP
DAPPSDTE-----------TTSEAESKD--------------------------------
-----------------------------------------------------
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
--------------MIAVSGPSYEAFSYGGQA---------RF-----------------
---------------NNQTVVDKVPPDMLHLI----DANWYQYPPLN-------------
---------------------------------PMWHGIL---GFVIGMLGFVSAMGNGM
VVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-SPPMVINCYY-ETWV--LGPLFCQIY
AMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSG-KPLSINGALIRIIAIWLFSLGW-TIAP
MF-GW-----NRYVPEGNMTACGTDYFNRG--LLSASYLVCYGIWVYFVPLFLIIYSYWF
IIQAVAAHEKNMREQAKK------------------------------------------
----------------------------------------------MNVASLRS------
------------------------------------------------------------
------------SENQNTS-----AECKLAKVALMTISLWFMAWTPYLVI-NFSGIF---
-NLVKISPLFTIWGSLFAKANAVYNPIVYGISHPKYRAALFAKFP-SLAC-AAE---PSS
DAVSTTSG-----------TTTVTDNEKSNA-----------------------------
-----------------------------------------------------
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
----------------MANQLSYSSLGWPYQP----------------------------
----------------NASVVDTMPKEMLYMI----HEHWYAFPPMN-------------
---------------------------------PLWYSIL---GVAMIILGIICVLGNGM
VIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-MPTMTSNCFA-ETWI--LGPFMCEVY
GMAGSLFGCASIWSMVMITLDRYNVIVRGMAA-APLTHKKATLLLLFVWIWSGGW-TILP
FF-GW-----SRYVPEGNLTSCTVDYLTKD--WSSASYVVIYGLAVYFLPLITMIYCYFF
IVHAVAEHEKQLREQAKK------------------------------------------
----------------------------------------------MNVASLRA------
------------------------------------------------------------
-----------NADQQKQS-----AECRLAKVAMMTVGLWFMAWTPYLII-SWAGVF---
SSGTRLTPLATIWGSVFAKANSCYNPIVYGISHPRYKAALYQRFP-SLACGSGE---SGS
DVKSEASA-----------TTTMEEKPKIPEA----------------------------
-----------------------------------------------------
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
---------------------MVESTTLVNQT----------WWY---------------
----------------NPTVD----------I----HPHWAKFDPIP-------------
---------------------------------DAVYYSV---GIFIGVVGIIGILGNGV
VIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLKTISAFM-KKWI--FGKVACQLY
GLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSHRRAFLMIIFVWMWSIVW-SVGP
VF-NW-----GAYVPEGILTSCSFDYLSTD--PSTRSFILCMYFCGFMLPIIIIAFCYFN
IVMSVSNHEKEMAAMAKR------------------------------------------
----------------------------------------------LNAKELR-------
------------------------------------------------------------
------------KAQAGAS-----AEMKLAKISMVIITQFMLSWSPYAII-ALLAQF---
GPAEWVTPYAAELPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCCQFDE-KECE
DANDAEEEVVASE--RGGESRDAAQMKEMMAMMQKMQAQQAAYQPPPPPQGY--PPQGYP
PQGAYPPPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVDNQAYQA
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
----------------------MGRDLRDNET----------WWY---------------
----------------NPSIV----------V----HPHWREFDQVP-------------
---------------------------------DAVYYSL---GIFIGICGIIGCGGNGI
VIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFL-KKWI--FGFAACKVY
GFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLW-AIGP
IF-GW-----GAYTLEGVLCNCSFDYISRD--STTRSNILCMFILGFFGPILIIFFCYFN
IVMSVSNHEKEMAAMAKR------------------------------------------
----------------------------------------------LNAKELR-------
------------------------------------------------------------
------------KAQAGAN-----AEMRLAKISIVIVSQFLLSWSPYAVV-ALLAQF---
GPLEWVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDD-KETE
DDKDAETEIPAGESSDAAPSADAAQMKEMMAMMQKMQQQQAAY----PPQGYAPPPQGYP
PQG--YPPQGYPPQGYPPQGYPP---PPQGAPPQ-GAPPAAPPQGVDNQAYQA
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
----------------------MMDVNSSGRPD--LYGHLRSFLLPEVGRGLPDLSPDGG
ADPVAGSWAPHLLS---EVTASP-------------APTWDAPPD---------------
-----------NASGCGEQI--NYGRVEK--------VVI---GSILTLITLLTIAGNCL
VVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVF
IAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASI-TLPP
LF-GW-----AQNVNDDKVCLISQDF----------GYTIYSTAVAFYIPMSVMLFMYYQ
IY-------KAARKSAAKHKF-----------------PGF-------------------
----------------P-----RV--EPDSVIALNG------------IVKLQK------
--------EVEE---------CANLSR---------------------------------
------LLKHERKNISIFK-----REQKAATTLGIIVGAFTVCWLPFFLL-STARPFICG
TSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQ----CQYRNINRKLS
AAGMHEALK----------LAERPERPEFVLQNADYCR----------------------
--------------------------------------KKGHDS---------
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
------------------------------------------------------------
--------MPHLLSGFLEVTASP-------------APTWDAPPD---------------
-----------NVSGCGEQI--NYGRVEK--------VVI---GSILTLITLLTIAGNCL
VVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVF
IAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASI-TLPP
LF-GW-----AQNVNDDKVCLISQDF----------GYTIYSTAVAFYIPMSVMLFMYYQ
IY-------KAARKSAAKHKF-----------------PGF-------------------
----------------P-----RV--QPESVISLNG------------VVKLQK------
--------EVEE---------CANLSR---------------------------------
------LLKHERKNISIFK-----REQKAATTLGIIVGAFTVCWLPFFLL-STARPFICG
TSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRPTSRSLLQ----CQYRNINRKLS
AAGMHEALK----------LAERPERSEFVLQNSDHCG----------------------
--------------------------------------KKGHDT---------
>    31=p A47425 serotonin receptor 5HT-7 - rat
------------------------------------------------------------
--------MPHLLSGFLEVTASP-------------APTWDAPPD---------------
-----------NVSGCGEQI--NYGRVEK--------VVI---GSILTLITLLTIAGNCL
VVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVF
IAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASI-TLPP
LF-GW-----AQNVNDDKVCLISQDF----------GYTIYSTAVAFYIPMSVMLFMYYQ
IY-------KAARKSAAKHKF-----------------PGF-------------------
----------------P-----RV--QPESVISLNG------------VVKLQK------
--------EVEE---------CANLSR---------------------------------
------LLKHERKNISIFK-----REQKAATTLGIIVGAFTVCWLPFFLL-STARPFICG
TSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQ----CQYRNINRKLS
AAGMHEALK----------LAERPERSEFVLQNSDHCG----------------------
--------------------------------------KKGHDT---------
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
-----------------------MDVLSPGQGN---------------------------
-----------------NTTSPP-------------APFE------------TGG-----
-----------NTTGISDVT--VSYQ-----------VIT---SLLLGTLIFCAVLGNAC
VVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NKWT--LGQVTCDLF
IALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLI-SIPP
ML-GWRTP---EDRSDPDACTISKDH----------GYTIYSTFGAFYIPLLLMLVLYGR
IF-------RAARFRIRK---------------------------------------TVK
KVEKTGADTRHGASPAP---------QPKKS--VNGESGSR---------NWRL------
--------GVESKAGGAL---CANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPT
PCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIV-ALVLPF-CE
SSCH-MPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIK----CKFCRQ-----
------------------------------------------------------------
-----------------------------------------------------
>    33=p A35181 serotonin receptor class 1A - rat
-----------------------MDVFSFGQGN---------------------------
-----------------NTTASQ-------------EPFG------------TGG-----
-----------NVTSISDVT--FSYQ-----------VIT---SLLLGTLIFCAVLGNAC
VVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NKWT--LGQVTCDLF
IALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLI-SIPP
ML-GWRTP---EDRSDPDACTISKDH----------GYTIYSTFGAFYIPLLLMLVLYGR
IF-------RAARFRIRK---------------------------------------TVR
KVEKKGAGTSLGTSSAP---------PPKKS--LNGQPGSG---------DWRR------
--------CAENRAVGTP---CTNGAVRQGDDEATLEVIEVHRVGNSKEHLPLPSESGSN
SYAPACLERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIV-ALVLPF-CE
SSCH-MPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIK----CKFCRR-----
------------------------------------------------------------
-----------------------------------------------------
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
-------------MANFTFGDLALDVARMG------------------------------
-----------------GLASTPSGLRSTGLTTPGLSPTGLVTSDFNDSYGLTGQFINGS
HSSRSRDNASANDTSATNMTDDRYW--SLTVYSHEHLVLT---SVILGLFVLCCIIGNCF
VIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KVWF--LHSEVCDMW
ISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMVVWIVALFI-SIPP
LF-GWRDP--NNDPDKTGTCIISQDK----------GYTIFSTVGAFYLPMLVMMIIYIR
IW-------LVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNSPDSTTE
KKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSS----------SERLKQIQIE
TAEAFANGCAEEASIAMLERQCNNGKKISSNDTPYS------------------------
---------RTREKLELK------RERKAARTLAIITGAFLICWLPFFII-ALIGPF-VD
--PEGIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILF----GKYRRGHR---
------------------------------------------------------------
-----------------------------------------------------
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
-------------MANFTFGDLALDVARMG------------------------------
-----------------GLASTPSGLRSTGLTTPGLSPTGLVTSDFNDSYGLTGQFINGS
HSSRSRDNASANDTSATNMTDDRYW--SLTVYSHEHLVLT---SVILGLFVLCCIIGNCF
VIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KVWF--LHSEVCDMW
ISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMVVWIVALFI-SIPP
LF-GWRDP--NNDPDKTGTCIISQDK----------GYTIFSTVGAFYLPMLVMMIIYIR
IW-------LVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNSPDSTTE
KKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSS----------SERLKQIQIE
TAEAFANGCAEEASIAMLERQCNNGKKISSNDTPYS------------------------
---------RTREKLELK------RERKAARTLAIITGAFLICWLPFFII-ALIGPF-VD
--PEGIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILF----GKYRRGHR---
------------------------------------------------------------
-----------------------------------------------------
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
--------------MEGAEGQEELDWEAL-------------------------------
------------------YLRLP--LQNCSWNSTGWEPNW--------------------
-----------NVTVVPNTT---WWQASAPFDTPAALVRAAAKAVVLGLLILATVVGNVF
VIAAILLERHLRSAANNLILSLAVADLLVACLV-MPLGAVYEVV-QRWT--LGPELCDMW
TSGDVLCCTASILHLVAIALDRYWAVTN-IDYIHASTAKRVGMMIACVWTVSFFV-CIAQ
LL-GWKDPDWNQRVSEDLRCVVSQDV----------GYQIFATASSFYVPVLIILILYWR
IY-------QTARKRIR-------------------------------------------
--RRRGATARGGVGPPP---------VPAGGALVAGGGSGGIAAAVVAVIGRPLPTISET
TTTGFTN--VSSNNTSPEKQSCANGLE---ADPPTTGYGAV-----------------AA
AYYPSLVRRKPKEAADSK------RERKAAKTLAIITGAFVACWLPFFVL-AILVPT-CD
--CE-VSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRLLC----GRRVRRRRA--
-----------------------PQ-----------------------------------
-----------------------------------------------------
