>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
---------------MNG--T---------------------------------------
-----------------EG-DNF-----------------YVP----FSNKTGLARSP--
-------YEYPQ--YYLAEPW---------KYSALAAYMFFLILVGFPVNFLTLFVTVQH
KKLRTPLNYILLNLAMANLFMVLFG-FTVTMYTSMN-GYFV--FGPTMCSIEGFFATLGG
EVALWSLVVLAIERYIVICKPMGN-FRFGNTHAIMGVAFTWIMALAC-AAPPLVG-WS--
---RYIPEGMQCSCGPDYYTLNPNFNNESYVVYMFVVHFLVPFVIIFFCYGRLLCTVKEA
AAAQQE-SASTQ------------------------------------------------
--------------------------------------K---------------------
------------------------------------------------------------
----AEKEVTRMVVLMVIGFLVCWVPYASVAFYIFT-HQGSD--FGATFMTLPAFFAKSS
ALYNPVIYILMNKQFRNCMITT----LCCG------K------NPLGDDE----------
--SGASTSKTEVSSV-S-----------TSPVSPA-------------------------
-----------------------------------------------
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
---------------MNG--T---------------------------------------
-----------------EG-PNF-----------------YVP----FSNITGVVRSP--
-------FEQPQ--YYLAEPW---------QFSMLAAYMFLLIVLGFPINFLTLYVTVQH
KKLRTPLNYILLNLAVADLFMVFGG-FTTTLYTSLH-GYFV--FGPTGCNLEGFFATLGG
EIGLWSLVVLAIERYVVVCKPMSN-FRFGENHAIMGVAFTWVMALAC-AAPPLVG-WS--
---RYIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIVIFFCYGQLVFTVKEA
AAQQQE-SATTQ------------------------------------------------
--------------------------------------K---------------------
------------------------------------------------------------
----AEKEVTRMVIIMVIFFLICWLPYASVAMYIFT-HQGSN--FGPIFMTLPAFFAKTA
SIYNPIIYIMMNKQFRNCMLTS----LCCG------K------NPLGDDE----------
--ASATASKTE-----------------TSQVAPA-------------------------
-----------------------------------------------
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
---------------MNG--T---------------------------------------
-----------------EG-INF-----------------YVP----MSNKTGVVRSP--
-------FEYPQ--YYLAEPW---------KYRLVCCYIFFLISTGLPINLLTLLVTFKH
KKLRQPLNYILVNLAVADLFMACFG-FTVTFYTAWN-GYFV--FGPVGCAVEGFFATLGG
QVALWSLVVLAIERYIVVCKPMGN-FRFSATHAMMGIAFTWVMAFSC-AAPPLFG-WS--
---RYMPEGMQCSCGPDYYTHNPDYHNESYVLYMFVIHFIIPVVVIFFSYGRLICKVREA
AAQQQE-SATTQ------------------------------------------------
--------------------------------------K---------------------
------------------------------------------------------------
----AEKEVTRMVILMVLGFMLAWTPYAVVAFWIFT-NKGAD--FTATLMAVPAFFSKSS
SLYNPIIYVLMNKQFRNCMITT----ICCG------K------NPFGDEDV---------
-SSTVSQSKTEVSSV-S-----------SSQVSPA-------------------------
-----------------------------------------------
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
---------------MNG--T---------------------------------------
-----------------EG-KNF-----------------YVP----MSNRTGLVRSP--
-------FEYPQ--YYLAEPW---------QFKILALYLFFLMSMGLPINGLTLVVTAQH
KKLRQPLNFILVNLAVAGTIMVCFG-FTVTFYTAIN-GYFV--LGPTGCAVEGFMATLGG
EVALWSLVVLAIERYIVVCKPMGS-FKFSSSHAFAGIAFTWVMALAC-AAPPLFG-WS--
---RYIPEGMQCSCGPDYYTLNPDYNNESYVIYMFVCHFILPVAVIFFTYGRLVCTVKAA
AAQQQD-SASTQ------------------------------------------------
--------------------------------------K---------------------
------------------------------------------------------------
----AEREVTKMVILMVFGFLIAWTPYATVAAWIFF-NKGAD--FSAKFMAIPAFFSKSS
ALYNPVIYVLLNKQFRNCMLTT----IFCG------K------NPLGDDE----------
-SSTVSTSKTEVSS-----------------VSPA-------------------------
-----------------------------------------------
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
---------------MNG--T---------------------------------------
-----------------EG-NNF-----------------YVP----LSNRTGLVRSP--
-------FEYPQ--YYLAEPW---------QFKLLAVYMFFLICLGLPINGLTLICTAQH
KKLRQPLNFILVNLAVAGAIMVCFG-FTVTFYTAIN-GYFA--LGPTGCAVEGFMATLGG
EVALWSLVVLAIERYIVVCKPMGS-FKFSSTHASAGIAFTWVMAMAC-AAPPLVG-WS--
---RYIPEGIQCSCGPDYYTLNPEYNNESYVLYMFICHFILPVTIIFFTYGRLVCTVKAA
AAQQQD-SASTQ------------------------------------------------
--------------------------------------K---------------------
------------------------------------------------------------
----AEREVTKMVILMVLGFLVAWTPYATVAAWIFF-NKGAA--FSAQFMAIPAFFSKTS
ALYNPVIYVLLNKQFRSCMLTT----LFCG------K------NPLGDEE----------
-SSTVSTSKTEVSS-----------------VSPA-------------------------
-----------------------------------------------
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
---------------MKQ--VPEF------------------------------------
----------H------E---DF-----------------YIPIPLDINNLS--AYSP--
-------FLVPQ--DHLGNQG---------IFMAMSVFMFFIFIGGASINILTILCTIQF
KKLRSHLNYILVNLSIANLFVAIFG-SPLSFYSFFN-RYFI--FGATACKIEGFLATLGG
MVGLWSLAVVAFERWLVICKPLGN-FTFKTPHAIAGCILPWISALAA-SLPPLFG-WS--
---RYIPEGLQCSCGPDWYTTNNKYNNESYVMFLFCFCFAVPFGTIVFCYGQLLITLKLA
AKAQAD-SASTQ------------------------------------------------
--------------------------------------K---------------------
------------------------------------------------------------
----AEREVTKMVVVMVLGFLVCWAPYASFSLWIVS-HRGEE--FDLRMATIPSCLSKAS
TVYNPVIYVLMNKQFRSCMMK-----MVCG------K------N-IEEDE----------
--ASTSSQVTQVSS-----------------VAPEK------------------------
-----------------------------------------------
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
---------------MRK--MSE-------------------------------------
-----------------E---EF-----------------YL-----FKNIS--SVGP--
-------WDGPQ--YHIAPVW---------AFYLQAAFMGTVFLIGFPLNAMVLVATLRY
KKLRQPLNYILVNVSFGGFLLCIFS-VFPVFVASCN-GYFV--FGRHVCALEGFLGTVAG
LVTGWSLAFLAFERYIVICKPFGN-FRFSSKHALTVVLATWTIGIGV-SIPPFFG-WS--
---RFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLICFSYTQLLRALKAV
AAQQQE-SATTQ------------------------------------------------
--------------------------------------K---------------------
------------------------------------------------------------
----AEREVSRMVVVMVGSFCVCYVPYAAFAMYMVN-NRNHG--LDLRLVTIPSFFSKSA
CIYNPIIYCFMNKQFQACIMK-----MVCG------K------A-MTDES----------
--DTCSSQKTEVSTV-S-----------STQVGPN-------------------------
-----------------------------------------------
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------DLAETVIA-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCG
ITGLWSLAIISWERWLVVCKPFGN-VRFDAKLAIVGIAFSWIWAAVW-TAPPIFG-WS--
---RYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAV
AKQQKE-SESTQ------------------------------------------------
--------------------------------------K---------------------
------------------------------------------------------------
----AEKEVTRMVVVMVLAFC---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
---------------MAQQWSLQR-------------LAGR-------------------
--------HPQ------DSYEDSTQSSI----------FTYTN-----SNST---RGP--
-------FEGPN--YHIAPRW---------VYHLTSVWMIFVVIASVFTNGLVLAATMKF
KKLRHPLNWILVNLAVADLAETVIA-STISVVNQVY-GYFV--LGHPMCVLEGYTVSLCG
ITGLWSLAIISWERWMVVCKPFGN-VRFDAKLAIVGIAFSWIWAAVW-TAPPIFG-WS--
---RYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAV
AKQQKE-SESTQ------------------------------------------------
--------------------------------------K---------------------
------------------------------------------------------------
----AEKEVTRMVVVMVLAFCFCWGPYAFFACFAAA-NPGYP--FHPLMAALPAFFAKSA
TIYNPVIYVFMNRQFRNCILQL----FG--------K------K-VDDGS----------
--ELSSASKTEVSSV--------------SSVSPA-------------------------
-----------------------------------------------
>    10== Z68193   1 human Red Opsin <>[]
---------------MAQQWSLQR-------------LAGR-------------------
--------HPQ------DSYEDSTQSSI----------FTYTN-----SNST---RGP--
-------FEGPN--YHIAPRW---------VYHLTSVWMIFVVTASVFTNGLVLAATMKF
KKLRHPLNWILVNLAVADLAETVIA-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCG
ITGLWSLAIISWERWLVVCKPFGN-VRFDAKLAIVGIAFSWIWSAVW-TAPPIFG-WS--
---RYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAIRAV
AKQQKE-SESTQ------------------------------------------------
--------------------------------------K---------------------
------------------------------------------------------------
----AEKEVTRMVVVMIFAYCVCWGPYTFFACFAAA-NPGYA--FHPLMAALPAYFAKSA
TIYNPVIYVFMNRQFRNCILQL----FG--------K------K-VDDGS----------
--ELSSASKTEVSSV--------------SSVSPA-------------------------
-----------------------------------------------
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
---------------MTE--AWNVA-----------VFAAR-------------------
--------RSR------DD-DDTTRGSV----------FTYTN-----TNNT---RGP--
-------FEGPN--YHIAPRW---------VYNLVSFFMIIVVIASCFTNGLVLVATAKF
KKLRHPLNWILVNLAFVDLVETLVA-STISVFNQIF-GYFI--LGHPLCVIEGYVVSSCG
ITGLWSLAIISWERWFVVCKPFGN-IKFDSKLAIIGIVFSWVWAWGW-SAPPIFG-WS--
---RYWPHGLKTSCGPDVFSGSVELGCQSFMLTLMITCCFLPLFIIIVCYLQVWMAIRAV
AAQQKE-SESTQ------------------------------------------------
--------------------------------------K---------------------
------------------------------------------------------------
----AEREVSRMVVVMIVAFCICWGPYASFVSFAAA-NPGYA--FHPLAAALPAYFAKSA
TIYNPVIYVFMNRQFRNCIMQL----FG--------K------K-VDDGS----------
--EASTTSRTEVSSV-S-----------NSSVAPA-------------------------
-----------------------------------------------
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
---------------MA---AWEAA------------FAAR-------------------
--------RRH------EE-EDTTRDSV----------FTYTN-----SNNT---RGP--
-------FEGPN--YHIAPRW---------VYNLTSVWMIFVVAASVFTNGLVLVATWKF
KKLRHPLNWILVNLAVADLGETVIA-STISVINQIS-GYFI--LGHPMCVVEGYTVSACG
ITALWSLAIISWERWFVVCKPFGN-IKFDGKLAVAGILFSWLWSCAW-TAPPIFG-WS--
---RYWPHGLKTSCGPDVFSGSSDPGVQSYMVVLMVTCCFFPLAIIILCYLQVWLAIRAV
AAQQKE-SESTQ------------------------------------------------
--------------------------------------K---------------------
------------------------------------------------------------
----AEKEVSRMVVVMIVAYCFCWGPYTFFACFAAA-NPGYA--FHPLAAALPAYFAKSA
TIYNPIIYVFMNRQFRNCILQL----FG--------K------K-VDDGS----------
--EVST-SRTEVSSV-S-----------NSSVSPA-------------------------
-----------------------------------------------
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
---------------MS-------------------------------------------
--------------------SNSSQ----------------AP-----PNGT---PGP--
-------FDGPQWPYQ-APQS---------TYVGVAVLMGTVVACASVVNGLVIVVSICY
KKLRSPLNYILVNLAVADLLVTLCG-SSVSLSNNIN-GFFV--FGRRMCELEGFMVSLTG
IVGLWSLAILALERYVVVCKPLGD-FQFQRRHAVSGCAFTWGWALLW-SAPPLLG-WS--
---SYVPEGLRTSCGPNWYTGGSNN--NSYILSLFVTCFVLPLSLILFSYTNLLLTLRAA
AAQQKE-ADTTQ------------------------------------------------
--------------------------------------R---------------------
------------------------------------------------------------
----AEREVTRMVIVMVMAFLLCWLPYSTFALVVAT-HKGII--IQPVLASLPSYFSKTA
TVYNPIIYVFMNKQFQSCLLEM----LCCGYQ---PQ------R-TGKAS----------
--PGTPGPHADVTAA-GL----------RNKVMPAH------------------------
--------------------PV-------------------------
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
---------------MESGNV-SSS-----------LF----------------------
--------------------GNVS-TALRPEARLSA------------ETRLLGWNVP--
----------PEELRHIPEHWLTYPEPPESMNYLLGTLYIFFTLMSMLGNGLVIWVFSAA
KSLRTPSNILVINLAFCDF-MMMVK-TPIFIYNSFH-QGYA--LGHLGCQIFGIIGSYTG
IAAGATNAFIAYDRFNVITRPMEG--KMTHGKAIAMIIFIYMYATPW-VVACYTETWG--
---RFVPEGYLTSCTFDYLTD--NFDTRLFVACIFFFSFVCPTTMITYYYSQI---VGHV
FSHEKALRDQAK------------------------------------------------
--------------------------------------KM----NVES-----------L
RSNVD------------------------------------------KNKET--------
----AEIRIAKAAITICFLFFCSWTPYGVMSLIGAF-GDKTL--LTPGATMIPACACKMV
ACIDPFVYAISHPRYRMELQKRCPW-LAL--------------NEKAPESS---------
--AVASTSTTQ-----E-----------P-QQTTAA------------------------
-----------------------------------------------
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
---------------MEYHNV-SSV-----------L-----------------------
--------------------GNVS-SVLRPDARLSA------------ESRLLGWNVP--
----------PDELRHIPEHWLIYPEPPESMNYLLGTLYIFFTVISMIGNGLVMWVFSAA
KSLRTPSNILVINLAFCDF-MMMIK-TPIFIYNSFH-QGYA--LGHLGCQIFGVIGSYTG
IAAGATNAFIAYDRYNVITRPMEG--KMTHGKAIAMIIFIYLYATPW-VVACYTESWG--
---RFVPEGYLTSCTFDYLTD--NFDTRLFVACIFFFSFVCPTTMITYYYSQI---VGHV
FSHEKALRDQAK------------------------------------------------
--------------------------------------KM----NVDS-----------L
RSNVD------------------------------------------KSKEA--------
----AEIRIAKAAITICFLFFASWTPYGVMSLIGAF-GDKTL--LTPGATMIPACTCKMV
ACIDPFVYAISHPRYRMELQKRCPW-LAI--------------SEKAPESR---------
--AAISTSTTQ-----E-----------Q-QQTTAA------------------------
-----------------------------------------------
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
---------------ME-------P-----------L-----------------------
--------------------CNASEPPLRPEAR-SSG---NG------DLQFLGWNVP--
----------PDQIQYIPEHWLTQLEPPASMHYMLGVFYIFLFCASTVGNGMVIWIFSTS
KSLRTPSNMFVLNLAVFDL-IMCLK-APIF--NSFH-RGFAIYLGNTWCQIFASIGSYSG
IGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFWD--
---RFVPEGYLTSCSFDYLSD--NFDTRLFVGTIFFFSFVCPTLMILYYYSQI---VGHV
FSHEKALREQAK------------------------------------------------
--------------------------------------KM----NVES-----------L
RSNVD------------------------------------------KSKET--------
----AEIRIAKAAITICFLFFVSWTPYGVMSLIGAF-GDKSL--LTQGATMIPACTCKLV
ACIDPFVYAISHPRYRLELQKRCPW-LGV--------------NEKSGEIS---------
--SAQST-TTQ-----E-----------Q-QQTTAA------------------------
-----------------------------------------------
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
---------------MD-------A-----------L-----------------------
--------------------CNASEPPLRPEARMSSG---SD------ELQFLGWNVP--
----------PDQIQYIPEHWLTQLEPPASMHYMLGVFYIFLFFASTLGNGMVIWIFSTS
KSLRTPSNMFVLNLAVFDL-IMCLK-APIFIYNSFH-RGFA--LGNTWCQIFASIGSYSG
IGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFWD--
---RFVPEGYLTSCSFDYLSD--NFDTRLFVGTIFLFSFVVPTLMILYYYSQI---VGHV
FNHEKALREQAK------------------------------------------------
--------------------------------------KM----NVES-----------L
RSNVD------------------------------------------KSKET--------
----AEIRIAKAAITICFLFFVSWTPYGVMSLIGAF-GDKSL--LTPGATMIPACTCKLV
ACIEPFVYAISHPRYRMELQKRCPW-LGV--------------NEKSGEAS---------
--SAQST-TTQ-----E-----------QTQQTSAA------------------------
-----------------------------------------------
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
-------------------------------------M----------------------
--------------------TNATGPQMAYYGAASMD-FGYP------EGVSIVDFVR--
----------PEIKPYVHQHWYNYPPVNPMWHYLLGVIYLFLGTVSIFGNGLVIYLFNKS
AALRTPANILVVNLALSDLIMLTTN-VPFFTYNCFSGGVWM--FSPQYCEIYACLGAITG
VCSIWLLCMISFDRYNIICNGFNG-PKLTTGKAVVFALISWVIAIGC-ALPPFFG-WG--
---NYILEGILDSCSYDYLTQ--DFNTFSYNIFIFVFDYFLPAAIIVFSYVFI---VKAI
FAHEAAMRAQAK------------------------------------------------
--------------------------------------KM----NVST-----------L
R-SNE------------------------------------------ADAQR--------
----AEIRIAKTALVNVSLWFICWTPYALISLKGVM-GDTSG--ITPLVSTLPALLAKSC
SCYNPFVYAISHPKYRLAITQHLPW-FCVH-ETE---------TKSNDDSQ---------
---SNSTVA-Q-----D-----------KA------------------------------
-----------------------------------------------
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
-------------------------------------M----------------------
--------------------ANVTGPQMAFYGSGAAT-FGYP------EGMTVADFVP--
----------DRVKHMVLDHWYNYPPVNPMWHYLLGVVYLFLGVISIAGNGLVIYLYMKS
QALKTPANMLIVNLALSDLIMLTTN-FPPFCYNCFSGGRWM--FSGTYCEIYAALGAITG
VCSIWTLCMISFDRYNIICNGFNG-PKLTQGKATFMCGLAWVISVGW-SLPPFFG-WG--
---SYTLEGILDSCSYDYFTR--DMNTITYNICIFIFDFFLPASVIVFSYVFI---VKAI
FAHEAAMRAQAK------------------------------------------------
--------------------------------------KM----NVTN-----------L
R-SNE------------------------------------------AETQR--------
----AEIRIAKTALVNVSLWFICWTPYAAITIQGLL-GNAEG--ITPLLTTLPALLAKSC
SCYNPFVYAISHPKFRLAITQHLPW-FCVH-EKD---------PNDVEENQ---------
---SSNTQT-Q-----E-----------KS------------------------------
-----------------------------------------------
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
---------------MESF-----A-----------VA----------------------
--------------------AAQLGPHFAPLS-----------------NGSVVDKVT--
----------PDMAHLISPYWNQFPAMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATT
KSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFG
CSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKM-----------------------
----YVPEGNLTSCGIDYLER--DWNPRSYLIFYSIFVYYIPLFLICYSYWFI---IAAV
SAHEKAMREQAK------------------------------------------------
--------------------------------------KM----NVKS-----------L
R-SSE------------------------------------------DAEKS--------
----AEGKLAKVALVTITLWFMAWTPYLVINCMGLF-KF-EG--LTPLNTIWGACFAKSA
ACYNPIVYGISHPKYRLALKEKCPC-CVFG-KVDDGK-------SSDAQSQ---------
---ATASEA-E-----S-----------KA------------------------------
-----------------------------------------------
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
---------------MESF-----A-----------VA----------------------
--------------------AAQLGPHFAPLS-----------------NGSVVDKVT--
----------PDMAHLISPYWNQFPAMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATT
KSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFG
CSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKIAYIWFMSSIW-CLAPAFG-WS--
---RYVPEGNLTSCGIDYLER--DWNPRSYLIFYSIFVYYIPLFLICYSYWFI---IAAV
SAHEKAMREQAK------------------------------------------------
--------------------------------------KM----NVKS-----------L
R-SSE------------------------------------------DAEKS--------
----AEGKLAKVALVTITLWFMAWTPYLVINCMGLF-KF-EG--LTPLNTIWGACFAKSA
ACYNPIVYGISHPKYRLALKEKCPC-CVFG-KVDDGK-------SSDAQSQ---------
---ATASEA-E-----S-----------KA------------------------------
-----------------------------------------------
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
---------------MDSF-----A-----------AV----------------------
--------------------ATQLGPQFAAPS-----------------NGSVVDKVT--
----------PDMAHLISPYWDQFPAMDPIWAKILTAYMIIIGMISWCGNGVVIYIFATT
KSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFG
CSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKIAYIWFMSTIWCCLAPVFG-WS--
---RYVPEGNLTSCGIDYLER--DWNPRSYLIFYSIFVYYIPLFLICYSYWFI---IAAV
SAHEKAMREQAK------------------------------------------------
--------------------------------------KM----NVKS-----------L
R-SSE------------------------------------------DADKS--------
----AEGKLAKVALVTISLWFMAWTPYLVINCMGLF-KF-EG--LTPLNTIWGACFAKSA
ACYNPIVYGISHPKYRLALKEKCPC-CVFG-KVDDGK-------SSEAQSQ---------
---ATTSEA-E-----S-----------KA------------------------------
-----------------------------------------------
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
---------------MERSHLPETP-----------FD----------------------
--------------------LAHSGPRFQAQSSG---------------NGSVLDNVL--
----------PDMAHLVNPYWSRFAPMDPMMSKILGLFTLAIMIISCCGNGVVVYIFGGT
KSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ETWV--LGPLWCDIYAGCGSLFG
CVSIWSMCMIAFDRYNVIVKGING-TPMTIKTSIMKILFIWMMAVFW-TVMPLIG-WS--
---AYVPEGNLTACSIDYMTR--MWNPRSYLITYSLFVYYTPLFLICYSYWFI---IAAV
AAHEKAMREQAK------------------------------------------------
--------------------------------------KM----NVKS-----------L
R-SSE------------------------------------------DCDKS--------
----AEGKLAKVALTTISLWFMAWTPYLVICYFGLF-KI-DG--LTPLTTIWGATFAKTS
AVYNPIVYGISHPKYRIVLKEKCPM-CVFG-NTDEPKPD---APASDTE-----------
----TTSEA-D-----S-----------KA------------------------------
-----------------------------------------------
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
---------------MERSLLPEPP-----------LA----------------------
--------------------MALLGPRFEAQTGG---------------NRSVLDNVL--
----------PDMAPLVNPHWSRFAPMDPTMSKILGLFTLVILIISCCGNGVVVYIFGGT
KSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ETWV--LGPLWCDIYAACGSLFG
CVSIWSMCMIAFDRYNVIVKGING-TPMTIKTSIMKIAFIWMMAVFW-TIMPLIG-WS--
---SYVPEGNLTACSIDYMTR--QWNPRSYLITYSLFVYYTPLFMICYSYWFI---IATV
AAHEKAMRDQAK------------------------------------------------
--------------------------------------KM----NVKS-----------L
R-SSE------------------------------------------DCDKS--------
----AENKLAKVALTTISLWFMAWTPYLIICYFGLF-KI-DG--LTPLTTIWGATFAKTS
AVYNPIVYGISHPNDRLVLKEKCPM-CVCG-TTDEPKPD---APPSDTE-----------
----TTSEA-E-----S-----------KD------------------------------
-----------------------------------------------
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
-------------------------------------M----------------------
--------------------IAVSGPSYEAFSYGGQARF---------NNQTVVDKVP--
----------PDMLHLIDANWYQYPPLNPMWHGILGFVIGMLGFVSAMGNGMVVYIFLST
KSLRTPSNLFVINLAISNFLMMFCM-SPPMVINCYY-ETWV--LGPLFCQIYAMLGSLFG
CGSIWTMTMIAFDRYNVIVKGLSG-KPLSINGALIRIIAIWLFSLGW-TIAPMFG-WN--
---RYVPEGNMTACGTDYFNR--GLLSASYLVCYGIWVYFVPLFLIIYSYWFI---IQAV
AAHEKNMREQAK------------------------------------------------
--------------------------------------KM----NVAS-----------L
R-SSE------------------------------------------NQNTS--------
----AECKLAKVALMTISLWFMAWTPYLVINFSGIF-NL-VK--ISPLFTIWGSLFAKAN
AVYNPIVYGISHPKYRAALFAKFPS-LAC--AAE---------PSSDAVSTT--------
--SGTTTVTDN-----E-----------KSNA----------------------------
-----------------------------------------------
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
------------------------------------------------------------
---------------------MANQLSYSSLGWPYQP------------NASVVDTMP--
----------KEMLYMIHEHWYAFPPMNPLWYSILGVAMIILGIICVLGNGMVIYLMMTT
KSLRTPTNLLVVNLAFSDFCMMAFM-MPTMTSNCFA-ETWI--LGPFMCEVYGMAGSLFG
CASIWSMVMITLDRYNVIVRGMAA-APLTHKKATLLLLFVWIWSGGW-TILPFFG-WS--
---RYVPEGNLTSCTVDYLTK--DWSSASYVVIYGLAVYFLPLITMIYCYFFI---VHAV
AEHEKQLREQAK------------------------------------------------
--------------------------------------KM----NVAS-----------L
RANAD------------------------------------------QQKQS--------
----AECRLAKVAMMTVGLWFMAWTPYLIISWAGVF-SSGTR--LTPLATIWGSVFAKAN
SCYNPIVYGISHPRYKAALYQRFPS-LACG-SGE---------SGSDVKSEA--------
--SATTTM--E-----E-----------KPKIPEA-------------------------
-----------------------------------------------
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
--------------MVES------T-----------TL----------------------
--------------------VNQT--------------WWY--------NPTVD------
----------------IHPHWAKFDPIPDAVYYSVGIFIGVVGIIGILGNGVVIYLFSKT
KSLQTPANMFIINLAMSDLSFSAINGFPLKTISAFM-KKWI--FGKVACQLYGLLGGIFG
FMSINTMAMISIDRYNVIGRPMAASKKMSHRRAFLMIIFVWMWSIVW-SVGPVFN-WG--
---AYVPEGILTSCSFDYLST--DPSTRSFILCMYFCGFMLPIIIIAFCYFNI---VMSV
SNHEKEMAAMAK------------------------------------------------
--------------------------------------RL----NAKE-----------L
R-KAQ------------------------------------------AGA-S--------
----AEMKLAKISMVIITQFMLSWSPYAIIALLAQF-GPAEW--VTPYAAELPVLFAKAS
AIHNPIVYSVSHPKFREAIQTTFPWLLTCC-QFDE-KEC---EDANDAEEEVVASERGGE
--SRDAAQMKEMMAMMQ-----------KMQAQQAAYQPPPPPQGY--PPQGYPPQGAYP
PPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVDNQAYQA
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
---------------MGR------D-----------LR----------------------
--------------------DNET--------------WWY--------NPSIV------
----------------VHPHWREFDQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKT
KSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFL-KKWI--FGFAACKVYGFIGGIFG
FMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLW-AIGPIFG-WG--
---AYTLEGVLCNCSFDYISR--DSTTRSNILCMFILGFFGPILIIFFCYFNI---VMSV
SNHEKEMAAMAK------------------------------------------------
--------------------------------------RL----NAKE-----------L
R-KAQ------------------------------------------AGA-N--------
----AEMRLAKISIVIVSQFLLSWSPYAVVALLAQF-GPLEW--VTPYAAQLPVMFAKAS
AIHNPMIYSVSHPKFREAISQTFPWVLTCC-QFDD-KET---EDDKDAETEIPAGESSDA
APSADAAQMKEMMAMMQ-----------KMQQQQAAY----PPQGYAPPPQGYPPQG-Y-
PPQGYPPQGYPPQGYPP---PPQGAPPQ-GAPPAAPPQGVDNQAYQA
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
--------------MMDVNSSGRPD-----LYGH--LRSFLLPEVGRGLPDLSPDG--GA
DPVAGSW-APHLLS---EV-TASPAPTWDAPP----------------DNASGCGEQIN-
-------YGRVE------------------K-VVIGSILTLITLLTIAGNCLVVISVCFV
KKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCC
TASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASI-TLPPLFG-WA--
---QNVNDDKVCLISQDF----------GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKS
AAKHKF----------------PGFPRVE-------------------------------
---P------------------------------------------DS----VIALNGIV
KLQKE------VEE--CANLSRLL-----------------------KHERKNISIFK--
----REQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYAN
SLINPFIYAFFNRDLRTTYRS-----LLQC------QYRNINRKLSAAGMH----E----
--ALKLAERPERP---EFVLQNADYCRKKGHDS---------------------------
-----------------------------------------------
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
------------------------------------------------------------
--------MPHLLSGFLEV-TASPAPTWDAPP----------------DNVSGCGEQIN-
-------YGRVE------------------K-VVIGSILTLITLLTIAGNCLVVISVSFV
KKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCC
TASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASI-TLPPLFG-WA--
---QNVNDDKVCLISQDF----------GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKS
AAKHKF----------------PGFPRVQ-------------------------------
---P------------------------------------------ES----VISLNGVV
KLQKE------VEE--CANLSRLL-----------------------KHERKNISIFK--
----REQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYAN
SLINPFIYAFFNRDLRPTSRS-----LLQC------QYRNINRKLSAAGMH----E----
--ALKLAERPERS---EFVLQNSDHCGKKGHDT---------------------------
-----------------------------------------------
>    31=p A47425 serotonin receptor 5HT-7 - rat
------------------------------------------------------------
--------MPHLLSGFLEV-TASPAPTWDAPP----------------DNVSGCGEQIN-
-------YGRVE------------------K-VVIGSILTLITLLTIAGNCLVVISVSFV
KKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCC
TASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASI-TLPPLFG-WA--
---QNVNDDKVCLISQDF----------GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKS
AAKHKF----------------PGFPRVQ-------------------------------
---P------------------------------------------ES----VISLNGVV
KLQKE------VEE--CANLSRLL-----------------------KHERKNISIFK--
----REQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYAN
SLINPFIYAFFNRDLRTTYRS-----LLQC------QYRNINRKLSAAGMH----E----
--ALKLAERPERS---EFVLQNSDHCGKKGHDT---------------------------
-----------------------------------------------
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
---------------MDVLSPGQGN-----------------------------------
--NTT----------------SPPAP-FET-G----------------GNTTGISDVT--
-------VSY-Q--------------------VITSLLLGTLIFCAVLGNACVVAAIALE
RSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLI-SIPPMLG-WRTP
E---DRSDPDACTISKDH----------GYTIYSTFGAFYIPLLLMLVLYGRIFRAARFR
IRK------TVK--------------KVEKTGADTRHG---------------------A
SPAPQPKKS------------------VNGESGSRNW-RL----GVESKAGGALCANGAV
RQGDDGAALEVIEVHRVGNSKE----HLPLP-SEAGPTPCAPASFERKNERN--AEAKRK
MALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF-CESSC-HMPTLLGAIINWLGYSN
SLLNPVIYAYFNKDFQNAFKK-----IIKC------KFC---------------------
----------------------------RQ------------------------------
-----------------------------------------------
>    33=p A35181 serotonin receptor class 1A - rat
---------------MDVFSFGQGN-----------------------------------
--NTT----------------ASQEP-FGT-G----------------GNVTSISDVT--
-------FSY-Q--------------------VITSLLLGTLIFCAVLGNACVVAAIALE
RSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLI-SIPPMLG-WRTP
E---DRSDPDACTISKDH----------GYTIYSTFGAFYIPLLLMLVLYGRIFRAARFR
IRK------TVR--------------KVEKKGAGTSLG---------------------T
SSAPPPKKS------------------LNGQPGSGDW-RR----CAENRAVGTPCTNGAV
RQGDDEATLEVIEVHRVGNSKE----HLPLP-SESGSNSYAPACLERKNERN--AEAKRK
MALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF-CESSC-HMPALLGAIINWLGYSN
SLLNPVIYAYFNKDFQNAFKK-----IIKC------KFC---------------------
----------------------------RR------------------------------
-----------------------------------------------
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
MANFTFGDLALDVARMGGLASTPSG-----------LRS-----TGLTTPGLSPTGLVTS
DFNDSYGLTGQFING-----SHSSRS-RDNAS----------------ANDTSATNMTDD
RYWSLTVYSH-E------------------HLVLTSVILGLFVLCCIIGNCFVIAAVMLE
RSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCC
TASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMVVWIVALFI-SIPPLFG-WRDP
NNDPDKTGT--CIISQDK----------GYTIFSTVGAFYLPMLVMMIIYIRIWLVARSR
IRKDKF--QMTKARLKTEETTLVASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGC
SPRPERKKNRAKKLP---ENANG----VNSNSSSSERLKQIQIETAEA------FANGCA
----EEASIAMLERQ-CNNGKKISSNDTP---YS-------------RTREK--LELK--
----RERKAARTLAIITGAFLICWLPFFIIALIGPF-VDPEG--IPPFARSFVLWLGYFN
SLLNPIIYTIFSPEFRSAFQK-----ILFG------KYR---------------------
----------------------------RGHR----------------------------
-----------------------------------------------
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
MANFTFGDLALDVARMGGLASTPSG-----------LRS-----TGLTTPGLSPTGLVTS
DFNDSYGLTGQFING-----SHSSRS-RDNAS----------------ANDTSATNMTDD
RYWSLTVYSH-E------------------HLVLTSVILGLFVLCCIIGNCFVIAAVMLE
RSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCC
TASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMVVWIVALFI-SIPPLFG-WRDP
NNDPDKTGT--CIISQDK----------GYTIFSTVGAFYLPMLVMMIIYIRIWLVARSR
IRKDKF--QMTKARLKTEETTLVASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGC
SPRPERKKNRAKKLP---ENANG----VNSNSSSSERLKQIQIETAEA------FANGCA
----EEASIAMLERQ-CNNGKKISSNDTP---YS-------------RTREK--LELK--
----RERKAARTLAIITGAFLICWLPFFIIALIGPF-VDPEG--IPPFARSFVLWLGYFN
SLLNPIIYTIFSPEFRSAFQK-----ILFG------KYR---------------------
----------------------------RGHR----------------------------
-----------------------------------------------
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
---------------MEG-AEGQEELDWEALYLRLPLQN-----CSWNSTGWEPNWNVTV
VPNTTWW--------------QASAP-FDTPA----------------ALVRAAAK----
-----------------------------------AVVLGLLILATVVGNVFVIAAILLE
RHLRSAANNLILSLAVADLLVACLV-MPLGAVYEVV-QRWT--LGPELCDMWTSGDVLCC
TASILHLVAIALDRYWAVTN-IDYIHASTAKRVGMMIACVWTVSFFV-CIAQLLG-WKDP
DWNQRVSEDLRCVVSQDV----------GYQIFATASSFYVPVLIILILYWRIYQTARKR
IRRRRG--ATAR-----GGVGPPPVPAGGALVAGGGSGGIAAAVVA-------------V
IGRP---------LPTISETTTTGFTNVSSNNTSPEK---------QS------CANG--
-----------LEA------------DPPTTGYGAVAAAYYPSLVRRKPKEA--ADSK--
----RERKAAKTLAIITGAFVACWLPFFVLAILVPT-CDCE---VSPVLTSLSLWLGYFN
STLNPVIYTVFSPEFRHAFQR-----LLCG------RRV---------------------
----------------------------RRRRAPQ-------------------------
-----------------------------------------------
