>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
----------MNGTE--------------GDNFYVP------------------------
-----------FSNKTGLARSPYEYPQY---------------------YLAEPWK----
-----YSALAAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-
FTVTMYTSMN-GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGN-F
RFGNTHAIMGVAFTWIMALAC-AAPPLVG-W-----SRYIPEGMQCSCGPDYYTLNPNFN
NESYVVYMFVVHFLVPFVIIFFCYGRLL-------CTVKEAAAA----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------QQ-ESASTQK------AEKEVTRMVVLMVIGFLVCWVPYAS
VAFYIFTHQGS---DFGATFMTLPAFFAKSSALYNPVIYILMNKQFRNCMITTLCC----
----GKNPLGDDE--SGASTSKTEVSSVS-TSPVSPA-----------------------
------------------------------------------------------------
------
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
----------MNGTE--------------GPNFYVP------------------------
-----------FSNITGVVRSPFEQPQY---------------------YLAEPWQ----
-----FSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-
FTTTLYTSLH-GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSN-F
RFGENHAIMGVAFTWVMALAC-AAPPLVG-W-----SRYIPEGMQCSCGIDYYTLKPEVN
NESFVIYMFVVHFTIPMIVIFFCYGQLV-------FTVKEAAAQ----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------QQ-ESATTQK------AEKEVTRMVIIMVIFFLICWLPYAS
VAMYIFTHQGS---NFGPIFMTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSLCC----
----GKNPLGDDE--ASATASKTE------TSQVAPA-----------------------
------------------------------------------------------------
------
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
----------MNGTE--------------GINFYVP------------------------
-----------MSNKTGVVRSPFEYPQY---------------------YLAEPWK----
-----YRLVCCYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-
FTVTFYTAWN-GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGN-F
RFSATHAMMGIAFTWVMAFSC-AAPPLFG-W-----SRYMPEGMQCSCGPDYYTHNPDYH
NESYVLYMFVIHFIIPVVVIFFSYGRLI-------CKVREAAAQ----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------QQ-ESATTQK------AEKEVTRMVILMVLGFMLAWTPYAV
VAFWIFTNKGA---DFTATLMAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTICC----
----GKNPFGDEDVSSTVSQSKTEVSSVS-SSQVSPA-----------------------
------------------------------------------------------------
------
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
----------MNGTE--------------GKNFYVP------------------------
-----------MSNRTGLVRSPFEYPQY---------------------YLAEPWQ----
-----FKILALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-
FTVTFYTAIN-GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-F
KFSSSHAFAGIAFTWVMALAC-AAPPLFG-W-----SRYIPEGMQCSCGPDYYTLNPDYN
NESYVIYMFVCHFILPVAVIFFTYGRLV-------CTVKAAAAQ----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------QQ-DSASTQK------AEREVTKMVILMVFGFLIAWTPYAT
VAAWIFFNKGA---DFSAKFMAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTIFC----
----GKNPLGDDE-SSTVSTSKTEVSS------VSPA-----------------------
------------------------------------------------------------
------
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
----------MNGTE--------------GNNFYVP------------------------
-----------LSNRTGLVRSPFEYPQY---------------------YLAEPWQ----
-----FKLLAVYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-
FTVTFYTAIN-GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-F
KFSSTHASAGIAFTWVMAMAC-AAPPLVG-W-----SRYIPEGIQCSCGPDYYTLNPEYN
NESYVLYMFICHFILPVTIIFFTYGRLV-------CTVKAAAAQ----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------QQ-DSASTQK------AEREVTKMVILMVLGFLVAWTPYAT
VAAWIFFNKGA---AFSAQFMAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTLFC----
----GKNPLGDEE-SSTVSTSKTEVSS------VSPA-----------------------
------------------------------------------------------------
------
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
----------MKQVPEF------------HEDFYIPIPL---------------------
----------DINNLS--AYSPFLVPQD---------------------HLGNQGI----
-----FMAMSVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-
SPLSFYSFFN-RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGN-F
TFKTPHAIAGCILPWISALAA-SLPPLFG-W-----SRYIPEGLQCSCGPDWYTTNNKYN
NESYVMFLFCFCFAVPFGTIVFCYGQLL-------ITLKLAAKA----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------QA-DSASTQK------AEREVTKMVVVMVLGFLVCWAPYAS
FSLWIVSHRGE---EFDLRMATIPSCLSKASTVYNPVIYVLMNKQFRSCMMKMVC-----
----GKNIEEDE---ASTSSQVTQVSS------VAPEK----------------------
------------------------------------------------------------
------
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
----------MRKMS--------------EEEFYL-------------------------
-----------FKNIS--SVGPWDGPQY---------------------HIAPVWA----
-----FYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-
VFPVFVASCN-GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGN-F
RFSSKHALTVVLATWTIGIGV-SIPPFFG-W-----SRFIPEGLQCSCGPDWYTVGTKYR
SESYTWFLFIFCFIVPLSLICFSYTQLL-------RALKAVAAQ----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------QQ-ESATTQK------AEREVSRMVVVMVGSFCVCYVPYAA
FAMYMVNNRNH---GLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIMKMVC-----
----GKAMTDES---DTCSSQKTEVSTVS-STQVGPN-----------------------
------------------------------------------------------------
------
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------DLAETVIA-
STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-V
RFDAKLAIVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPG
VQSYMIVLMVTCCITPLSIIVLCYLQVW-------LAIRAVAKQ----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------QK-ESESTQK------AEKEVTRMVVVMVLAFC--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
----------MAQQWSLQRLAGRHPQDSYEDSTQSSI-F---------------------
----------TYTNSNS-TRGPFEGPNY---------------------HIAPRWV----
-----YHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-
STISVVNQVY-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGN-V
RFDAKLAIVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPG
VQSYMIVLMVTCCITPLSIIVLCYLQVW-------LAIRAVAKQ----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------QK-ESESTQK------AEKEVTRMVVVMVLAFCFCWGPYAF
FACFAAANPGY---PFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLF------
----GKKVDDGS---ELSSASKTEVSSV---SSVSPA-----------------------
------------------------------------------------------------
------
>    10== Z68193   1 human Red Opsin <>[]
----------MAQQWSLQRLAGRHPQDSYEDSTQSSI-F---------------------
----------TYTNSNS-TRGPFEGPNY---------------------HIAPRWV----
-----YHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-
STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-V
RFDAKLAIVGIAFSWIWSAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPG
VQSYMIVLMVTCCIIPLAIIMLCYLQVW-------LAIRAVAKQ----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------QK-ESESTQK------AEKEVTRMVVVMIFAYCVCWGPYTF
FACFAAANPGY---AFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLF------
----GKKVDDGS---ELSSASKTEVSSV---SSVSPA-----------------------
------------------------------------------------------------
------
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
----------MTEAWNVAVFAARRSRDD-DDTTRGSV-F---------------------
----------TYTNTNN-TRGPFEGPNY---------------------HIAPRWV----
-----YNLVSFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-
STISVFNQIF-GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGN-I
KFDSKLAIIGIVFSWVWAWGW-SAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSVELG
CQSFMLTLMITCCFLPLFIIIVCYLQVW-------MAIRAVAAQ----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------QK-ESESTQK------AEREVSRMVVVMIVAFCICWGPYAS
FVSFAAANPGY---AFHPLAAALPAYFAKSATIYNPVIYVFMNRQFRNCIMQLF------
----GKKVDDGS---EASTTSRTEVSSVS-NSSVAPA-----------------------
------------------------------------------------------------
------
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
----------MA-AWEAA-FAARRRHEE-EDTTRDSV-F---------------------
----------TYTNSNN-TRGPFEGPNY---------------------HIAPRWV----
-----YNLTSVWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVIA-
STISVINQIS-GYFI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGN-I
KFDGKLAVAGILFSWLWSCAW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSDPG
VQSYMVVLMVTCCFFPLAIIILCYLQVW-------LAIRAVAAQ----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------QK-ESESTQK------AEKEVSRMVVVMIVAYCFCWGPYTF
FACFAAANPGY---AFHPLAAALPAYFAKSATIYNPIIYVFMNRQFRNCILQLF------
----GKKVDDGS---EVST-SRTEVSSVS-NSSVSPA-----------------------
------------------------------------------------------------
------
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
----------MS-----------------SNSSQAP------------------------
--------------PNG-TPGPFDGPQW--------------------PYQAPQST----
-----YVGVAVLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-
SSVSLSNNIN-GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGD-F
QFQRRHAVSGCAFTWGWALLW-SAPPLLG-W-----SSYVPEGLRTSCGPNWYTGGSNN-
-NSYILSLFVTCFVLPLSLILFSYTNLL-------LTLRAAAAQ----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------QK-EADTTQR------AEREVTRMVIVMVMAFLLCWLPYST
FALVVATHKGI---IIQPVLASLPSYFSKTATVYNPIIYVFMNKQFQSCLLEMLCC----
-GYQPQRTGKAS---PGTPGPHADVTAAGLRNKVMPAHPV--------------------
------------------------------------------------------------
------
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
----------ME-----------------SGNVSSSL-----------------------
-----------FGNVST-ALRPEARLSA------ETRLLGWNVPPEELRHIPEHWLTYPE
PPESMNYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK--
TPIFIYNSFH-QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--
KMTHGKAIAMIIFIYMYATPW-VVACYTETW-----GRFVPEGYLTSCTFDYLT--DNFD
TRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKK----------------
-----------------------------------------------------------M
N-----------VESL--------------------------------------------
-------------------RSNVDKNKET------AEIRIAKAAITICFLFFCSWTPYGV
MSLIGAFGDKT---LLTPGATMIPACACKMVACIDPFVYAISHPRYRMELQKRCPWLAL-
-------NEKAP---ESSAVASTSTTQEP--QQTTAA-----------------------
------------------------------------------------------------
------
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
----------ME-----------------YHNVSSVL-----------------------
------------GNVSS-VLRPDARLSA------ESRLLGWNVPPDELRHIPEHWLIYPE
PPESMNYLLGTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMIK--
TPIFIYNSFH-QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--
KMTHGKAIAMIIFIYLYATPW-VVACYTESW-----GRFVPEGYLTSCTFDYLT--DNFD
TRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKK----------------
-----------------------------------------------------------M
N-----------VDSL--------------------------------------------
-------------------RSNVDKSKEA------AEIRIAKAAITICFLFFASWTPYGV
MSLIGAFGDKT---LLTPGATMIPACTCKMVACIDPFVYAISHPRYRMELQKRCPWLAI-
-------SEKAP---ESRAAISTSTTQEQ--QQTTAA-----------------------
------------------------------------------------------------
------
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
----------ME------------------------------------------------
----------PLCNASEPPLRPEARSSG----NGDLQFLGWNVPPDQIQYIPEHWLTQLE
PPASMHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--
APIF--NSFH-RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--
NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFD
TRLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKK----------------
-----------------------------------------------------------M
N-----------VESL--------------------------------------------
-------------------RSNVDKSKET------AEIRIAKAAITICFLFFVSWTPYGV
MSLIGAFGDKS---LLTQGATMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWLGV-
-------NEKSG---EISSAQSTTTQEQ---QQTTAA-----------------------
------------------------------------------------------------
------
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
----------MD------------------------------------------------
----------ALCNASEPPLRPEARMSSG---SDELQFLGWNVPPDQIQYIPEHWLTQLE
PPASMHYMLGVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--
APIFIYNSFH-RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--
NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFD
TRLFVGTIFLFSFVVPTLMILYYYSQIVGHVFNHEKALREQAKK----------------
-----------------------------------------------------------M
N-----------VESL--------------------------------------------
-------------------RSNVDKSKET------AEIRIAKAAITICFLFFVSWTPYGV
MSLIGAFGDKS---LLTPGATMIPACTCKLVACIEPFVYAISHPRYRMELQKRCPWLGV-
-------NEKSG---EASSAQSTTTQEQT--QQTSAA-----------------------
------------------------------------------------------------
------
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
------------------------------------------------------------
-----------MTNATGPQMAYYGAASMD-FGYPEGVSIVDFVRPEIKPYVHQHWYNYPP
VNPMWHYLLGVIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTTN-
VPFFTYNCFSGGVWM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNG-P
KLTTGKAVVFALISWVIAIGC-ALPPFFG-W-----GNYILEGILDSCSYDYLT--QDFN
TFSYNIFIFVFDYFLPAAIIVFSYVFIVKAIFAHEAAMRAQAKK----------------
-----------------------------------------------------------M
N-----------VSTL--------------------------------------------
-------------------RS-NEADAQR------AEIRIAKTALVNVSLWFICWTPYAL
ISLKGVMGDTS---GITPLVSTLPALLAKSCSCYNPFVYAISHPKYRLAITQHLPWFCV-
-----HETETKS---NDDSQSNSTVAQDK-A-----------------------------
------------------------------------------------------------
------
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
------------------------------------------------------------
-----------MANVTGPQMAFYGSGAAT-FGYPEGMTVADFVPDRVKHMVLDHWYNYPP
VNPMWHYLLGVVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-
FPPFCYNCFSGGRWM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNG-P
KLTQGKATFMCGLAWVISVGW-SLPPFFG-W-----GSYTLEGILDSCSYDYFT--RDMN
TITYNICIFIFDFFLPASVIVFSYVFIVKAIFAHEAAMRAQAKK----------------
-----------------------------------------------------------M
N-----------VTNL--------------------------------------------
-------------------RS-NEAETQR------AEIRIAKTALVNVSLWFICWTPYAA
ITIQGLLGNAE---GITPLLTTLPALLAKSCSCYNPFVYAISHPKFRLAITQHLPWFCV-
-----HEKDPND---VEENQSSNTQTQEK-S-----------------------------
------------------------------------------------------------
------
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
----------ME---------------------SFAV-----------------------
-----------AAAQLGPHFAPLS-----------NGSVVDKVTPDMAHLISPYWNQFPA
MDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-
TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-R
PMTIPLALGKM---------------------------YVPEGNLTSCGIDYLE--RDWN
PRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKK----------------
-----------------------------------------------------------M
N-----------VKSL--------------------------------------------
-------------------RS-SEDAEKS------AEGKLAKVALVTITLWFMAWTPYLV
INCMGLFKF-E---GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF-
-----GKVDDGK---SSDAQSQA-TASEA-ESKA--------------------------
------------------------------------------------------------
------
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
----------ME---------------------SFAV-----------------------
-----------AAAQLGPHFAPLS-----------NGSVVDKVTPDMAHLISPYWNQFPA
MDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-
TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-R
PMTIPLALGKIAYIWFMSSIW-CLAPAFG-W-----SRYVPEGNLTSCGIDYLE--RDWN
PRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKK----------------
-----------------------------------------------------------M
N-----------VKSL--------------------------------------------
-------------------RS-SEDAEKS------AEGKLAKVALVTITLWFMAWTPYLV
INCMGLFKF-E---GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF-
-----GKVDDGK---SSDAQSQA-TASEA-ESKA--------------------------
------------------------------------------------------------
------
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
----------MD---------------------SFAA-----------------------
-----------VATQLGPQFAAPS-----------NGSVVDKVTPDMAHLISPYWDQFPA
MDPIWAKILTAYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-
TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-R
PMTIPLALGKIAYIWFMSTIWCCLAPVFG-W-----SRYVPEGNLTSCGIDYLE--RDWN
PRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKK----------------
-----------------------------------------------------------M
N-----------VKSL--------------------------------------------
-------------------RS-SEDADKS------AEGKLAKVALVTISLWFMAWTPYLV
INCMGLFKF-E---GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF-
-----GKVDDGK---SSEAQSQA-TTSEA-ESKA--------------------------
------------------------------------------------------------
------
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
MERS-----HLP---------------------ETPF-----------------------
-----------DLAHSGPRFQAQSSG---------NGSVLDNVLPDMAHLVNPYWSRFAP
MDPMMSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-
SPVMIINFYY-ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGING-T
PMTIKTSIMKILFIWMMAVFW-TVMPLIG-W-----SAYVPEGNLTACSIDYMT--RMWN
PRSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKK----------------
-----------------------------------------------------------M
N-----------VKSL--------------------------------------------
-------------------RS-SEDCDKS------AEGKLAKVALTTISLWFMAWTPYLV
ICYFGLFKI-D---GLTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMCVF-
-----GNTDEPK---PDAPASDTETTSEA-DSKA--------------------------
------------------------------------------------------------
------
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
MERS-----LLP---------------------EPPL-----------------------
-----------AMALLGPRFEAQTGG---------NRSVLDNVLPDMAPLVNPHWSRFAP
MDPTMSKILGLFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-
SPVMIINFYY-ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGING-T
PMTIKTSIMKIAFIWMMAVFW-TIMPLIG-W-----SSYVPEGNLTACSIDYMT--RQWN
PRSYLITYSLFVYYTPLFMICYSYWFIIATVAAHEKAMRDQAKK----------------
-----------------------------------------------------------M
N-----------VKSL--------------------------------------------
-------------------RS-SEDCDKS------AENKLAKVALTTISLWFMAWTPYLI
ICYFGLFKI-D---GLTPLTTIWGATFAKTSAVYNPIVYGISHPNDRLVLKEKCPMCVC-
-----GTTDEPK---PDAPPSDTETTSEA-ESKD--------------------------
------------------------------------------------------------
------
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
------------------------------------------------------------
-----------MIAVSGPSYEAFSYGGQARF---NNQTVVDKVPPDMLHLIDANWYQYPP
LNPMWHGILGFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-
SPPMVINCYY-ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSG-K
PLSINGALIRIIAIWLFSLGW-TIAPMFG-W-----NRYVPEGNMTACGTDYFN--RGLL
SASYLVCYGIWVYFVPLFLIIYSYWFIIQAVAAHEKNMREQAKK----------------
-----------------------------------------------------------M
N-----------VASL--------------------------------------------
-------------------RS-SENQNTS------AECKLAKVALMTISLWFMAWTPYLV
INFSGIFNL-V---KISPLFTIWGSLFAKANAVYNPIVYGISHPKYRAALFAKFPSLAC-
------AAEPSS---DAVSTTSGTTTVTD-NEKSNA------------------------
------------------------------------------------------------
------
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
------------------------------------------------------------
-----------MANQL--SYSSLGWPYQP------NASVVDTMPKEMLYMIHEHWYAFPP
MNPLWYSILGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-
MPTMTSNCFA-ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAA-A
PLTHKKATLLLLFVWIWSGGW-TILPFFG-W-----SRYVPEGNLTSCTVDYLT--KDWS
SASYVVIYGLAVYFLPLITMIYCYFFIVHAVAEHEKQLREQAKK----------------
-----------------------------------------------------------M
N-----------VASL--------------------------------------------
-------------------RANADQQKQS------AECRLAKVAMMTVGLWFMAWTPYLI
ISWAGVFSSGT---RLTPLATIWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPSLAC-
-----GSGESGS---DVKSEASATTTMEE-KPKIPEA-----------------------
------------------------------------------------------------
------
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
------------------------------------------------------------
------------------MVESTTLVNQT-WWY--NPTVD----------IHPHWAKFDP
IPDAVYYSVGIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAING
FPLKTISAFM-KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASK
KMSHRRAFLMIIFVWMWSIVW-SVGPVFN-W-----GAYVPEGILTSCSFDYLS--TDPS
TRSFILCMYFCGFMLPIIIIAFCYFNIVMSVSNHEKEMAAMAKR----------------
-----------------------------------------------------------L
N-----------AKEL--------------------------------------------
-------------------R--KAQAGAS------AEMKLAKISMVIITQFMLSWSPYAI
IALLAQFGPAE---WVTPYAAELPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTC
CQFDEKECEDAN---DAEEEVVASER--G-GESRDAAQMKEMMAMMQKMQAQQAAYQPPP
PPQGY--PPQGYPPQGAYPPPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVD
NQAYQA
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
------------------------------------------------------------
-------------------MGRDLRDNET-WWY--NPSIV----------VHPHWREFDQ
VPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNG
FPLMTISCFL-KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASK
KMSHRRAFIMIIFVWLWSVLW-AIGPIFG-W-----GAYTLEGVLCNCSFDYIS--RDST
TRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKR----------------
-----------------------------------------------------------L
N-----------AKEL--------------------------------------------
-------------------R--KAQAGAN------AEMRLAKISIVIVSQFLLSWSPYAV
VALLAQFGPLE---WVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTC
CQFDDKETEDDK---DAETEIPAGESSDA-APSADAAQMKEMMAMMQKMQQQQAAY----
PPQGYAPPPQGYPPQGY--PPQGYPPQGYPPQGYPP---PPQGAPPQ-GAPPAAPPQGVD
NQAYQA
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
M---------MDVNSS--------GRPDLYGHLRSFL-LPEVGRGLPDLSPDG--GADPV
AGSWAPHLLS---EVTASPAPTWDAPPD-------NASGCGE---------------QIN
YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-
MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPV
RQNGKCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF--------
--GYTIYSTAVAFYIPMSVMLFMYYQIY-------KAARKSAAKHKFP------------
--GFPRVE---------------------------------------------PDSVIAL
NG----------IVKLQK------------------------------EVEECAN-----
-------------LSRLLKHERKNISIFK------REQKAATTLGIIVGAFTVCWLPFFL
LSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYR-
--NINRKLSAAGM-HEALKLAERPERPEFVLQNADYCRKK--------------------
---------------------------------------------------------GHD
S-----
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
------------------------------------------------------------
----MPHLLSGFLEVTASPAPTWDAPPD-------NVSGCGE---------------QIN
YGRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-
MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPV
RQNGKCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF--------
--GYTIYSTAVAFYIPMSVMLFMYYQIY-------KAARKSAAKHKFP------------
--GFPRVQ---------------------------------------------PESVISL
NG----------VVKLQK------------------------------EVEECAN-----
-------------LSRLLKHERKNISIFK------REQKAATTLGIIVGAFTVCWLPFFL
LSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRPTSRSLLQCQYR-
--NINRKLSAAGM-HEALKLAERPERSEFVLQNSDHCGKK--------------------
---------------------------------------------------------GHD
T-----
>    31=p A47425 serotonin receptor 5HT-7 - rat
------------------------------------------------------------
----MPHLLSGFLEVTASPAPTWDAPPD-------NVSGCGE---------------QIN
YGRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-
MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPV
RQNGKCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF--------
--GYTIYSTAVAFYIPMSVMLFMYYQIY-------KAARKSAAKHKFP------------
--GFPRVQ---------------------------------------------PESVISL
NG----------VVKLQK------------------------------EVEECAN-----
-------------LSRLLKHERKNISIFK------REQKAATTLGIIVGAFTVCWLPFFL
LSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYR-
--NINRKLSAAGM-HEALKLAERPERSEFVLQNSDHCGKK--------------------
---------------------------------------------------------GHD
T-----
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
----------MDVLSP--------------------------------------------
----------GQGNNTTSPPAPFETGG--------NTTGISDVTVSY-------------
-----QVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-
LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVN
KRTPRRAAALISLTWLIGFLI-SIPPMLG-WRTPE-DRSDPDA--CTISKDH--------
--GYTIYSTFGAFYIPLLLMLVLYGRIF-------RAARFRIRK----------------
-----------------------TVKKVEKTGADTRHGASPAPQPKKS-----------V
NGESGSRNWRLGVESK---------AGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHL
PLPSEAG--PTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFI
VALVLPFCESSC--HMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC-
-----RQ-----------------------------------------------------
------------------------------------------------------------
------
>    33=p A35181 serotonin receptor class 1A - rat
----------MDVFSF--------------------------------------------
----------GQGNNTTASQEPFGTGG--------NVTSISDVTFSY-------------
-----QVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-
LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVN
KRTPRRAAALISLTWLIGFLI-SIPPMLG-WRTPE-DRSDPDA--CTISKDH--------
--GYTIYSTFGAFYIPLLLMLVLYGRIF-------RAARFRIRK----------------
-----------------------TVRKVEKKGAGTSLGTSSAPPPKKS-----------L
NGQPGSGDWRRCAENR---------AVGTPCTNGAVRQGDDEATLEVIEVHRVGNSKEHL
PLPSESG--SNSYAPACLERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFI
VALVLPFCESSC--HMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC-
-----RR-----------------------------------------------------
------------------------------------------------------------
------
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
MANFTFGDLALDVARM-------------GGLASTPSGLRSTGLTTPGLSPTGLVTSDFN
DSY---GLTGQFINGSHSSRSRDNASA--------NDTSATNMTDDR------YWS-LTV
YSHEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-
MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIR
RRSARRILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK--------
--GYTIFSTVGAFYLPMLVMMIIYIRIW-------LVARSRIRKDKFQMTKARLKTEETT
LVASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGV
NSNSSS------SERLKQ----IQIETAEAFANGCAEEASI-AMLE----RQCNNGKKIS
SNDTPYS------------RT-REKLELK------RERKAARTLAIITGAFLICWLPFFI
IALIGPFVDPE---GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYR-
---RGHR-----------------------------------------------------
------------------------------------------------------------
------
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
MANFTFGDLALDVARM-------------GGLASTPSGLRSTGLTTPGLSPTGLVTSDFN
DSY---GLTGQFINGSHSSRSRDNASA--------NDTSATNMTDDR------YWS-LTV
YSHEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-
MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIR
RRSARRILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK--------
--GYTIFSTVGAFYLPMLVMMIIYIRIW-------LVARSRIRKDKFQMTKARLKTEETT
LVASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGV
NSNSSS------SERLKQ----IQIETAEAFANGCAEEASI-AMLE----RQCNNGKKIS
SNDTPYS------------RT-REKLELK------RERKAARTLAIITGAFLICWLPFFI
IALIGPFVDPE---GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYR-
---RGHR-----------------------------------------------------
------------------------------------------------------------
------
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
----------MEGAEGQEELD--------WEALYLRLPLQNCSWNSTGWEPNWNVTVVPN
TTWWQ-------------ASAPFDTPAAL----VR-------------------------
-----AAAKAVVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACLV-
MPLGAVYEVV-QRWT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIH
ASTAKRVGMMIACVWTVSFFV-CIAQLLG-WKDPDWNQRVSEDLRCVVSQDV--------
--GYQIFATASSFYVPVLIILILYWRIY-------QTARKRIRR----------------
-----------------------------RRGATARGGVGPPP---------VPAGGALV
AGGGSGGIAAAVVAVIGRPLPTISETTTTGFTNVSSNNTSP-------EKQSCANGLEAD
PPTTGYGAVAAAYYPSLVRRKPKEAADSK------RERKAAKTLAIITGAFVACWLPFFV
LAILVPTCDCE----VSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRLLCGRRV-
---RRRR-----------------------------------------------------
APQ---------------------------------------------------------
------
