>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
------------------------------------------------------------
---------------------------------MNGTEGDNFYVPFSNKTGLARSPYEYP
QY-YLAEPWKYSALAAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFM
VLFG-FTVTMYTSMN-GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKP
MGN-FRFGNTHAIMGVAFTWIMALAC-AAPPLVGW-----SRYIPEGMQCSCGPDYYTLN
PNFNNESYVVYMFVVHFLVPFVIIFFCYGRLLCTVKEAAAAQQ-----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------ESASTQKAEKEVTRMVVLMVIGFLVC
WVPYASVAFYIFTHQGS---DFGATFMTLPAFFAKSSALYNPVIYILMNKQFRNCMITTL
CCGKNPLGDDE--SGASTSKTEVSSVS-TSPVSPA-------------------------
------------------------------------------------------------
---------
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
------------------------------------------------------------
---------------------------------MNGTEGPNFYVPFSNITGVVRSPFEQP
QY-YLAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFM
VFGG-FTTTLYTSLH-GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKP
MSN-FRFGENHAIMGVAFTWVMALAC-AAPPLVGW-----SRYIPEGMQCSCGIDYYTLK
PEVNNESFVIYMFVVHFTIPMIVIFFCYGQLVFTVKEAAAQQQ-----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------ESATTQKAEKEVTRMVIIMVIFFLIC
WLPYASVAMYIFTHQGS---NFGPIFMTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSL
CCGKNPLGDDE--ASATASKTETSQVA-PA------------------------------
------------------------------------------------------------
---------
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
------------------------------------------------------------
---------------------------------MNGTEGINFYVPMSNKTGVVRSPFEYP
QY-YLAEPWKYRLVCCYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFM
ACFG-FTVTFYTAWN-GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKP
MGN-FRFSATHAMMGIAFTWVMAFSC-AAPPLFGW-----SRYMPEGMQCSCGPDYYTHN
PDYHNESYVLYMFVIHFIIPVVVIFFSYGRLICKVREAAAQQQ-----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------ESATTQKAEKEVTRMVILMVLGFMLA
WTPYAVVAFWIFTNKGA---DFTATLMAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTI
CCGKNPFGDEDVSSTVSQSKTEVSSVS-SSQVSPA-------------------------
------------------------------------------------------------
---------
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
------------------------------------------------------------
---------------------------------MNGTEGKNFYVPMSNRTGLVRSPFEYP
QY-YLAEPWQFKILALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIM
VCFG-FTVTFYTAIN-GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKP
MGS-FKFSSSHAFAGIAFTWVMALAC-AAPPLFGW-----SRYIPEGMQCSCGPDYYTLN
PDYNNESYVIYMFVCHFILPVAVIFFTYGRLVCTVKAAAAQQQ-----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------DSASTQKAEREVTKMVILMVFGFLIA
WTPYATVAAWIFFNKGA---DFSAKFMAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTI
FCGKNPLGDDE-SSTVSTSKTEVSSVS-PA------------------------------
------------------------------------------------------------
---------
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
------------------------------------------------------------
---------------------------------MNGTEGNNFYVPLSNRTGLVRSPFEYP
QY-YLAEPWQFKLLAVYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIM
VCFG-FTVTFYTAIN-GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKP
MGS-FKFSSTHASAGIAFTWVMAMAC-AAPPLVGW-----SRYIPEGIQCSCGPDYYTLN
PEYNNESYVLYMFICHFILPVTIIFFTYGRLVCTVKAAAAQQQ-----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------DSASTQKAEREVTKMVILMVLGFLVA
WTPYATVAAWIFFNKGA---AFSAQFMAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTL
FCGKNPLGDEE-SSTVSTSKTEVSSVS-PA------------------------------
------------------------------------------------------------
---------
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
------------------------------------------------------------
-----------------------------MKQVPEFHEDFYIPIPLDINNLSAYSPFLVP
QD-HLGNQGIFMAMSVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFV
AIFG-SPLSFYSFFN-RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKP
LGN-FTFKTPHAIAGCILPWISALAA-SLPPLFGW-----SRYIPEGLQCSCGPDWYTTN
NKYNNESYVMFLFCFCFAVPFGTIVFCYGQLLITLKLAAKAQA-----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------DSASTQKAEREVTKMVVVMVLGFLVC
WAPYASFSLWIVSHRGE---EFDLRMATIPSCLSKASTVYNPVIYVLMNKQFRSCMM-KM
VCGKNIEEDE---ASTSSQVTQVSSVA-PEK-----------------------------
------------------------------------------------------------
---------
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
------------------------------------------------------------
---------------------------------MRKMSEEEFYL---FKNISSVGPWDGP
QY-HIAPVWAFYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLL
CIFS-VFPVFVASCN-GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKP
FGN-FRFSSKHALTVVLATWTIGIGV-SIPPFFGW-----SRFIPEGLQCSCGPDWYTVG
TKYRSESYTWFLFIFCFIVPLSLICFSYTQLLRALKAVAAQQQ-----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------ESATTQKAEREVSRMVVVMVGSFCVC
YVPYAAFAMYMVNNRNH---GLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIM-KM
VCGKAMTDES---DTCSSQKTEVSTVS-STQVGPN-------------------------
------------------------------------------------------------
---------
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------DLAE
TVIA-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKP
FGN-VRFDAKLAIVGIAFSWIWAAVW-TAPPIFGW-----SRYWPHGLKTSCGPDVFSGS
SYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQQK-----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------ESESTQKAEKEVTRMVVVMVLAFC--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
------------------------------------------MAQQWSLQRLAG------
-----------------------------RHPQDSYEDSTQSSIFTYTNSNSTRGPFEGP
NY-HIAPRWVYHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAE
TVIA-STISVVNQVY-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKP
FGN-VRFDAKLAIVGIAFSWIWAAVW-TAPPIFGW-----SRYWPHGLKTSCGPDVFSGS
SYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQQK-----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------ESESTQKAEKEVTRMVVVMVLAFCFC
WGPYAFFACFAAANPGY---PFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLF
-----GKKVDDGSELSSASKTEVSSV---SSVSPA-------------------------
------------------------------------------------------------
---------
>    10== Z68193   1 human Red Opsin <>[]
------------------------------------------MAQQWSLQRLAG------
-----------------------------RHPQDSYEDSTQSSIFTYTNSNSTRGPFEGP
NY-HIAPRWVYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAE
TVIA-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKP
FGN-VRFDAKLAIVGIAFSWIWSAVW-TAPPIFGW-----SRYWPHGLKTSCGPDVFSGS
SYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAIRAVAKQQK-----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------ESESTQKAEKEVTRMVVVMIFAYCVC
WGPYTFFACFAAANPGY---AFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLF
-----GKKVDDGSELSSASKTEVSSV---SSVSPA-------------------------
------------------------------------------------------------
---------
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
------------------------------------------MTEAWNVAVFAA------
-----------------------------RRSRDD-DDTTRGSVFTYTNTNNTRGPFEGP
NY-HIAPRWVYNLVSFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVE
TLVA-STISVFNQIF-GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKP
FGN-IKFDSKLAIIGIVFSWVWAWGW-SAPPIFGW-----SRYWPHGLKTSCGPDVFSGS
VELGCQSFMLTLMITCCFLPLFIIIVCYLQVWMAIRAVAAQQK-----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------ESESTQKAEREVSRMVVVMIVAFCIC
WGPYASFVSFAAANPGY---AFHPLAAALPAYFAKSATIYNPVIYVFMNRQFRNCIMQLF
-----GKKVDDGSEASTTSRTEVSSVS-NSSVAPA-------------------------
------------------------------------------------------------
---------
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
-------------------------------------------MAAWEAAFAAR------
-----------------------------RRHEE--EDTTRDSVFTYTNSNNTRGPFEGP
NY-HIAPRWVYNLTSVWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGE
TVIA-STISVINQIS-GYFI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKP
FGN-IKFDGKLAVAGILFSWLWSCAW-TAPPIFGW-----SRYWPHGLKTSCGPDVFSGS
SDPGVQSYMVVLMVTCCFFPLAIIILCYLQVWLAIRAVAAQQK-----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------ESESTQKAEKEVSRMVVVMIVAYCFC
WGPYTFFACFAAANPGY---AFHPLAAALPAYFAKSATIYNPIIYVFMNRQFRNCILQLF
-----GKKVDDGSEVST-SRTEVSSVS-NSSVSPA-------------------------
------------------------------------------------------------
---------
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
------------------------------------------------------------
----------------------------------------MSSNSSQAPPNGTPGPFDGP
QWPYQAPQSTYVGVAVLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLV
TLCG-SSVSLSNNIN-GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKP
LGD-FQFQRRHAVSGCAFTWGWALLW-SAPPLLGW-----SSYVPEGLRTSCGPNWYTGG
SNN--NSYILSLFVTCFVLPLSLILFSYTNLLLTLRAAAAQQK-----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------EADTTQRAEREVTRMVIVMVMAFLLC
WLPYSTFALVVATHKGI---IIQPVLASLPSYFSKTATVYNPIIYVFMNKQFQSCLLEML
CCGYQPQRTGKASPGTPGPHADVTAAGLRNKVMPAHPV----------------------
------------------------------------------------------------
---------
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
------------------MESGNV--------------SSSLFGNVSTALRPEA------
-----------------------------RLSA-----ETRLLGWNVPPEELRHIPEHWL
TY-PEPPESMNYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMM
MVK--TPIFIYNSFH-QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRP
MEG--KMTHGKAIAMIIFIYMYATPWVVACYTETW-----GRFVPEGYLTSCTFDYLTDN
FDT--RLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKKMNVESLRS----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------NVDKNKETAEIRIAKAAITICFLFFCS
WTPYGVMSLIGAFGDKT---LLTPGATMIPACACKMVACIDPFVYAISHPRYRMELQKRC
PWLALNEKAPESSAVASTSTTQEPQQTTAA------------------------------
------------------------------------------------------------
---------
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
------------------MEYHNV--------------SSVL-GNVSSVLRPDA------
-----------------------------RLSA-----ESRLLGWNVPPDELRHIPEHWL
IY-PEPPESMNYLLGTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMM
MIK--TPIFIYNSFH-QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRP
MEG--KMTHGKAIAMIIFIYLYATPWVVACYTESW-----GRFVPEGYLTSCTFDYLTDN
FDT--RLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKKMNVDSLRS----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------NVDKSKEAAEIRIAKAAITICFLFFAS
WTPYGVMSLIGAFGDKT---LLTPGATMIPACTCKMVACIDPFVYAISHPRYRMELQKRC
PWLAISEKAPESRAAISTSTTQEQQQTTAA------------------------------
------------------------------------------------------------
---------
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
--------------------------------------MEPLCNASEPPLRPEA------
-----------------------------R-SSGNG--DLQFLGWNVPPDQIQYIPEHWL
TQ-LEPPASMHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIM
CLK--APIF--NSFH-RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKP
MNR--NMTFTKAVIMNIIIWLYCTPWVVLPLTQFW-----DRFVPEGYLTSCSFDYLSDN
FDT--RLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKKMNVESLRS----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------NVDKSKETAEIRIAKAAITICFLFFVS
WTPYGVMSLIGAFGDKS---LLTQGATMIPACTCKLVACIDPFVYAISHPRYRLELQKRC
PWLGVNEKSGEISSAQSTTTQEQQQTTAA-------------------------------
------------------------------------------------------------
---------
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
--------------------------------------MDALCNASEPPLRPEA------
-----------------------------RMSSGSD--ELQFLGWNVPPDQIQYIPEHWL
TQ-LEPPASMHYMLGVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIM
CLK--APIFIYNSFH-RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKP
MNR--NMTFTKAVIMNIIIWLYCTPWVVLPLTQFW-----DRFVPEGYLTSCSFDYLSDN
FDT--RLFVGTIFLFSFVVPTLMILYYYSQIVGHVFNHEKALREQAKKMNVESLRS----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------NVDKSKETAEIRIAKAAITICFLFFVS
WTPYGVMSLIGAFGDKS---LLTPGATMIPACTCKLVACIEPFVYAISHPRYRMELQKRC
PWLGVNEKSGEASSAQSTTTQEQTQQTSAA------------------------------
------------------------------------------------------------
---------
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
-----------------------------------------MTNATGPQMAYYG------
-----------------------------AASMDFGYPEGVSIVDFVRPEIKPYVHQHWY
NY-PPVNPMWHYLLGVIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIM
LTTN-VPFFTYNCFSGGVWM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNG
FNG-PKLTTGKAVVFALISWVIAIGC-ALPPFFGW-----GNYILEGILDSCSYDYLTQD
FNT--FSYNIFIFVFDYFLPAAIIVFSYVFIVKAIFAHEAAMRAQAKKMNVSTLRS----
------------------------------------------------------------
------------------------------------------------------------
----------------------------------NEADAQRAEIRIAKTALVNVSLWFIC
WTPYALISLKGVMGDTS---GITPLVSTLPALLAKSCSCYNPFVYAISHPKYRLAITQHL
PWFCVHETETKSNDDSQSNSTVAQDKA---------------------------------
------------------------------------------------------------
---------
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
-----------------------------------------MANVTGPQMAFYG------
-----------------------------SGAATFGYPEGMTVADFVPDRVKHMVLDHWY
NY-PPVNPMWHYLLGVVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIM
LTTN-FPPFCYNCFSGGRWM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNG
FNG-PKLTQGKATFMCGLAWVISVGW-SLPPFFGW-----GSYTLEGILDSCSYDYFTRD
MNT--ITYNICIFIFDFFLPASVIVFSYVFIVKAIFAHEAAMRAQAKKMNVTNLRS----
------------------------------------------------------------
------------------------------------------------------------
----------------------------------NEAETQRAEIRIAKTALVNVSLWFIC
WTPYAAITIQGLLGNAE---GITPLLTTLPALLAKSCSCYNPFVYAISHPKFRLAITQHL
PWFCVHEKDPNDVEENQSSNTQTQEKS---------------------------------
------------------------------------------------------------
---------
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
---------------------MES--------------FAVAAAQLGPHFAPLS------
---------------------------------------NGSVVDKVTPDMAHLISPYWN
QF-PAMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGI
MITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKG
MAG-RPMTIPLALGKM--------------------------YVPEGNLTSCGIDYLERD
WNP--RSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLRS----
------------------------------------------------------------
------------------------------------------------------------
----------------------------------SEDAEKSAEGKLAKVALVTITLWFMA
WTPYLVINCMGLFKF-E---GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKC
PCCVFGKVDDGKSSDAQSQA-TASEAESKA------------------------------
------------------------------------------------------------
---------
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
---------------------MES--------------FAVAAAQLGPHFAPLS------
---------------------------------------NGSVVDKVTPDMAHLISPYWN
QF-PAMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGI
MITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKG
MAG-RPMTIPLALGKIAYIWFMSSIW-CLAPAFGW-----SRYVPEGNLTSCGIDYLERD
WNP--RSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLRS----
------------------------------------------------------------
------------------------------------------------------------
----------------------------------SEDAEKSAEGKLAKVALVTITLWFMA
WTPYLVINCMGLFKF-E---GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKC
PCCVFGKVDDGKSSDAQSQA-TASEAESKA------------------------------
------------------------------------------------------------
---------
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
---------------------MDS--------------FAAVATQLGPQFAAPS------
---------------------------------------NGSVVDKVTPDMAHLISPYWD
QF-PAMDPIWAKILTAYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGI
MITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKG
MAG-RPMTIPLALGKIAYIWFMSTIWCCLAPVFGW-----SRYVPEGNLTSCGIDYLERD
WNP--RSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLRS----
------------------------------------------------------------
------------------------------------------------------------
----------------------------------SEDADKSAEGKLAKVALVTISLWFMA
WTPYLVINCMGLFKF-E---GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKC
PCCVFGKVDDGKSSEAQSQA-TTSEAESKA------------------------------
------------------------------------------------------------
---------
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
----------------MERSHLPE--------------TPFDLAHSGPRFQAQS------
-----------------------------SG--------NGSVLDNVLPDMAHLVNPYWS
RF-APMDPMMSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCM
MASQ-SPVMIINFYY-ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKG
ING-TPMTIKTSIMKILFIWMMAVFW-TVMPLIGW-----SAYVPEGNLTACSIDYMTRM
WNP--RSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKKMNVKSLRS----
------------------------------------------------------------
------------------------------------------------------------
----------------------------------SEDCDKSAEGKLAKVALTTISLWFMA
WTPYLVICYFGLFKI-D---GLTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKC
PMCVFGNTDEPKPDAPASDTETTSEADSKA------------------------------
------------------------------------------------------------
---------
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
----------------MERSLLPE--------------PPLAMALLGPRFEAQT------
-----------------------------GG--------NRSVLDNVLPDMAPLVNPHWS
RF-APMDPTMSKILGLFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCM
MASQ-SPVMIINFYY-ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKG
ING-TPMTIKTSIMKIAFIWMMAVFW-TIMPLIGW-----SSYVPEGNLTACSIDYMTRQ
WNP--RSYLITYSLFVYYTPLFMICYSYWFIIATVAAHEKAMRDQAKKMNVKSLRS----
------------------------------------------------------------
------------------------------------------------------------
----------------------------------SEDCDKSAENKLAKVALTTISLWFMA
WTPYLIICYFGLFKI-D---GLTPLTTIWGATFAKTSAVYNPIVYGISHPNDRLVLKEKC
PMCVCGTTDEPKPDAPPSDTETTSEAESKD------------------------------
------------------------------------------------------------
---------
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
-----------------------------------------MIAVSGPSYEAFS------
-----------------------------YGGQARF--NNQTVVDKVPPDMLHLIDANWY
QY-PPLNPMWHGILGFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLM
MFCM-SPPMVINCYY-ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKG
LSG-KPLSINGALIRIIAIWLFSLGW-TIAPMFGW-----NRYVPEGNMTACGTDYFNRG
LLS--ASYLVCYGIWVYFVPLFLIIYSYWFIIQAVAAHEKNMREQAKKMNVASLRS----
------------------------------------------------------------
------------------------------------------------------------
----------------------------------SENQNTSAECKLAKVALMTISLWFMA
WTPYLVINFSGIFNL-V---KISPLFTIWGSLFAKANAVYNPIVYGISHPKYRAALFAKF
PSLAC-AAEPSSDAVSTTSGTTTVTDNEKSNA----------------------------
------------------------------------------------------------
---------
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
-------------------------------------------MANQLSYSSLG------
-----------------------------WPYQP-----NASVVDTMPKEMLYMIHEHWY
AF-PPMNPLWYSILGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCM
MAFM-MPTMTSNCFA-ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRG
MAA-APLTHKKATLLLLFVWIWSGGW-TILPFFGW-----SRYVPEGNLTSCTVDYLTKD
WSS--ASYVVIYGLAVYFLPLITMIYCYFFIVHAVAEHEKQLREQAKKMNVASLRA----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------NADQQKQSAECRLAKVAMMTVGLWFMA
WTPYLIISWAGVFSSGT---RLTPLATIWGSVFAKANSCYNPIVYGISHPRYKAALYQRF
PSLACGSGESGSDVKSEASATTTMEEKPKIPEA---------------------------
------------------------------------------------------------
---------
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
------------------------------------------------MVESTT------
-----------------------------LVNQTWWY--NPTVD----------IHPHWA
KF-DPIPDAVYYSVGIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSF
SAINGFPLKTISAFM-KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRP
MAASKKMSHRRAFLMIIFVWMWSIVW-SVGPVFNW-----GAYVPEGILTSCSFDYLSTD
PST--RSFILCMYFCGFMLPIIIIAFCYFNIVMSVSNHEKEMAAMAKRLNAKELR-----
------------------------------------------------------------
------------------------------------------------------------
----------------------------------KAQAGASAEMKLAKISMVIITQFMLS
WSPYAIIALLAQFGPAE---WVTPYAAELPVLFAKASAIHNPIVYSVSHPKFREAIQTTF
PWLLTCCQFDEKECEDANDAEEEVVASER--GGESRDAAQMKEMMAMMQKMQAQQAAYQP
---PPPPQGYPPQGYPPQGAYPPPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQ
GVDNQAYQA
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
-------------------------------------------------MGRDL------
-----------------------------RDNETWWY--NPSIV----------VHPHWR
EF-DQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTF
SLVNGFPLMTISCFL-KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRP
MAASKKMSHRRAFIMIIFVWLWSVLW-AIGPIFGW-----GAYTLEGVLCNCSFDYISRD
STT--RSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKRLNAKELR-----
------------------------------------------------------------
------------------------------------------------------------
----------------------------------KAQAGANAEMRLAKISIVIVSQFLLS
WSPYAVVALLAQFGPLE---WVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTF
PWVLTCCQFDDKETEDDKDAETEIPAGESSDAAPSADAAQMKEMMAMMQKMQQQQAAYPP
QGYAPPPQGYPPQGYPPQGY--PPQGYPPQGYPP---PPQGAPPQGAPP------AAPPQ
GVDNQAYQA
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
---------------MMDVNSSGR----PDLYGHLRSFLLPEVGRGLPDLSPDGGADPVA
GSWAPHLLS---EVTASPAPTWD------------APPDNASGCGEQINY----------
------GRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSV
AVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRP
LTYPVRQNGKCMAKMILSVWLLSASI-TLPPLFGW-----AQNVNDDKVCLISQD-----
-----FGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPG--------------
------------------------------------------------------------
------------------------------------FPRVEPDSVIALNGIVKLQKEVE-
---ECAN------------------LSRLLKHERKNISIFKREQKAATTLGIIVGAFTVC
WLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLL
QCQYRNINRKLSAAGMHEALKLAERPERPEFVLQNADYCRKKGHDS--------------
------------------------------------------------------------
---------
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
------------------------------------------------------------
---MPHLLSGFLEVTASPAPTWD------------APPDNVSGCGEQINY----------
------GRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSV
AVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRP
LTYPVRQNGKCMAKMILSVWLLSASI-TLPPLFGW-----AQNVNDDKVCLISQD-----
-----FGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPG--------------
------------------------------------------------------------
------------------------------------FPRVQPESVISLNGVVKLQKEVE-
---ECAN------------------LSRLLKHERKNISIFKREQKAATTLGIIVGAFTVC
WLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRPTSRSLL
QCQYRNINRKLSAAGMHEALKLAERPERSEFVLQNSDHCGKKGHDT--------------
------------------------------------------------------------
---------
>    31=p A47425 serotonin receptor 5HT-7 - rat
------------------------------------------------------------
---MPHLLSGFLEVTASPAPTWD------------APPDNVSGCGEQINY----------
------GRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSV
AVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRP
LTYPVRQNGKCMAKMILSVWLLSASI-TLPPLFGW-----AQNVNDDKVCLISQD-----
-----FGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPG--------------
------------------------------------------------------------
------------------------------------FPRVQPESVISLNGVVKLQKEVE-
---ECAN------------------LSRLLKHERKNISIFKREQKAATTLGIIVGAFTVC
WLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLL
QCQYRNINRKLSAAGMHEALKLAERPERSEFVLQNSDHCGKKGHDT--------------
------------------------------------------------------------
---------
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
----------------MDVLSPGQ---------------GNNTTSPPAPFETGG------
------------NTTGISDVTVS-------------------------------------
---------YQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMV
SVLV-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDP
IDYVNKRTPRRAAALISLTWLIGFLI-SIPPMLGWRTPEDRSDPD---ACTISKD-----
-----HGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK-------------------
--------------------TVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVE
SKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNER-
------------------------------NAEAKRKMALARERKTVKTLGIIMGTFILC
WLPFFIVALVLPFCESSC--HMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKII
KCKFCRQ-----------------------------------------------------
------------------------------------------------------------
---------
>    33=p A35181 serotonin receptor class 1A - rat
----------------MDVFSFGQ---------------GNNTTASQEPFGTGG------
------------NVTSISDVTFS-------------------------------------
---------YQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMV
SVLV-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDP
IDYVNKRTPRRAAALISLTWLIGFLI-SIPPMLGWRTPEDRSDPD---ACTISKD-----
-----HGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK-------------------
--------------------TVRKVEKKGAGTSLGTSSAPPPKKSLNGQPGSGDWRRCAE
NRAVGTPCTNGAVRQGDDEATLEVIEVHRVGNSKEHLPLPSESGSNSYAPACLERKNER-
------------------------------NAEAKRKMALARERKTVKTLGIIMGTFILC
WLPFFIVALVLPFCESSC--HMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKII
KCKFCRR-----------------------------------------------------
------------------------------------------------------------
---------
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
------MANFTFGDLALDVARMGGLASTPS--------GLRSTGLTTPGLSPTG------
------------LVTSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATNM---TDDRYW
SL-TVYSHEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMV
AVLV-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-
IDYIRRRSARRILLMIMVVWIVALFI-SIPPLFGWRDP--NNDPDKTGTCIISQD-----
-----KGYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVA
SPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKK----------------
NRAKKLPENANGVNSNSSS--------------SERLKQIQIETAEAFANGCAEEASIAM
LERQCNNGKKISSNDTPYS-------------RTREKLELKRERKAARTLAIITGAFLIC
WLPFFIIALIGPFVDPE---GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKIL
FGKYRRGHR---------------------------------------------------
------------------------------------------------------------
---------
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
------MANFTFGDLALDVARMGGLASTPS--------GLRSTGLTTPGLSPTG------
------------LVTSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATNM---TDDRYW
SL-TVYSHEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMV
AVLV-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-
IDYIRRRSARRILLMIMVVWIVALFI-SIPPLFGWRDP--NNDPDKTGTCIISQD-----
-----KGYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVA
SPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKK----------------
NRAKKLPENANGVNSNSSS--------------SERLKQIQIETAEAFANGCAEEASIAM
LERQCNNGKKISSNDTPYS-------------RTREKLELKRERKAARTLAIITGAFLIC
WLPFFIIALIGPFVDPE---GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKIL
FGKYRRGHR---------------------------------------------------
------------------------------------------------------------
---------
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
MEGAEGQEELDWEALYLRLP-------------------LQNCSWNSTGWEPNW------
------------NVTVVPNTTWW---------QASAPFDTPAALVRAAAK----------
--------------AVVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLV
ACLV-MPLGAVYEVV-QRWT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-
IDYIHASTAKRVGMMIACVWTVSFFV-CIAQLLGWKDPDWNQRVSEDLRCVVSQD-----
-----VGYQIFATASSFYVPVLIILILYWRIYQTARKRIR--------------------
-------------------------RRRGATARGGVGPPP--------------------
-----VPAGGALVAGGGSGGIAAAV----VAVIGRPLPTISETTTTGFTNVSSNNTSPE-
-KQSCANGLEADPPTTGYGAVAAAYYPSLVRRKPKEAADSKRERKAAKTLAIITGAFVAC
WLPFFVLAILVPTCDCE----VSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRLL
CGRRVRRRRAPQ------------------------------------------------
------------------------------------------------------------
---------
