>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
--------------------MN--------------------------------------
-----------------------GTE--GDNFY------------VPFSNKTG-------
---------------LARSPYEYPQY-------------YLAEPWKYSALAAYMFFLILV
GFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-FTVTMYTSMN-GYFV--FG
PTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGNF-RFGNTHAIMGVAFTWIMAL
ACAAP-PLVG-WS-----RYIPEGMQCSCGPDYYTLNPNFNNESYVVYMFVVHFLVPFVI
IFFCYGRLLCTVKEAAAAQQESA-------------------------------------
------------------------------------------------------------
--------------------------------------------STQKAEKEVTRMVVLM
VIGFLVCWVPYASVAFYIFT-HQGS-D-FGATFMTLPAFFAKSSALYNPVIYILMNKQFR
NCMITTLCC----GKNPLGDDE-SGA-STSKTEVSSVS-TSPV-----------------
------------------------------------------------------------
--------------------SPA---
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
--------------------MN--------------------------------------
-----------------------GTE--GPNFY------------VPFSNITG-------
---------------VVRSPFEQPQY-------------YLAEPWQFSMLAAYMFLLIVL
GFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTTLYTSLH-GYFV--FG
PTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSNF-RFGENHAIMGVAFTWVMAL
ACAAP-PLVG-WS-----RYIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIV
IFFCYGQLVFTVKEAAAQQQESA-------------------------------------
------------------------------------------------------------
--------------------------------------------TTQKAEKEVTRMVIIM
VIFFLICWLPYASVAMYIFT-HQGS-N-FGPIFMTLPAFFAKTASIYNPIIYIMMNKQFR
NCMLTSLCC----GKNPLGDDE-ASA-TASKTE------TSQV-----------------
------------------------------------------------------------
--------------------APA---
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
--------------------MN--------------------------------------
-----------------------GTE--GINFY------------VPMSNKTG-------
---------------VVRSPFEYPQY-------------YLAEPWKYRLVCCYIFFLIST
GLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-FTVTFYTAWN-GYFV--FG
PVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGNF-RFSATHAMMGIAFTWVMAF
SCAAP-PLFG-WS-----RYMPEGMQCSCGPDYYTHNPDYHNESYVLYMFVIHFIIPVVV
IFFSYGRLICKVREAAAQQQESA-------------------------------------
------------------------------------------------------------
--------------------------------------------TTQKAEKEVTRMVILM
VLGFMLAWTPYAVVAFWIFT-NKGA-D-FTATLMAVPAFFSKSSSLYNPIIYVLMNKQFR
NCMITTICC----GKNPFGDEDVSSTVSQSKTEVSSVS-SSQV-----------------
------------------------------------------------------------
--------------------SPA---
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
--------------------MN--------------------------------------
-----------------------GTE--GKNFY------------VPMSNRTG-------
---------------LVRSPFEYPQY-------------YLAEPWQFKILALYLFFLMSM
GLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-FTVTFYTAIN-GYFV--LG
PTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGSF-KFSSSHAFAGIAFTWVMAL
ACAAP-PLFG-WS-----RYIPEGMQCSCGPDYYTLNPDYNNESYVIYMFVCHFILPVAV
IFFTYGRLVCTVKAAAAQQQDSA-------------------------------------
------------------------------------------------------------
--------------------------------------------STQKAEREVTKMVILM
VFGFLIAWTPYATVAAWIFF-NKGA-D-FSAKFMAIPAFFSKSSALYNPVIYVLLNKQFR
NCMLTTIFC----GKNPLGDDE-SSTVSTSKTEVSS------V-----------------
------------------------------------------------------------
--------------------SPA---
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
--------------------MN--------------------------------------
-----------------------GTE--GNNFY------------VPLSNRTG-------
---------------LVRSPFEYPQY-------------YLAEPWQFKLLAVYMFFLICL
GLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-FTVTFYTAIN-GYFA--LG
PTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGSF-KFSSTHASAGIAFTWVMAM
ACAAP-PLVG-WS-----RYIPEGIQCSCGPDYYTLNPEYNNESYVLYMFICHFILPVTI
IFFTYGRLVCTVKAAAAQQQDSA-------------------------------------
------------------------------------------------------------
--------------------------------------------STQKAEREVTKMVILM
VLGFLVAWTPYATVAAWIFF-NKGA-A-FSAQFMAIPAFFSKTSALYNPVIYVLLNKQFR
SCMLTTLFC----GKNPLGDEE-SSTVSTSKTEVSS------V-----------------
------------------------------------------------------------
--------------------SPA---
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
--------------------MK--------------------------------------
-----------------------QVPEFHEDFY------------IPIPLDINN------
--------------LSAYSPFLVPQD-------------HLGNQGIFMAMSVFMFFIFIG
GASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-SPLSFYSFFN-RYFI--FG
ATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGNF-TFKTPHAIAGCILPWISAL
AASLP-PLFG-WS-----RYIPEGLQCSCGPDWYTTNNKYNNESYVMFLFCFCFAVPFGT
IVFCYGQLLITLKLAAKAQADSA-------------------------------------
------------------------------------------------------------
--------------------------------------------STQKAEREVTKMVVVM
VLGFLVCWAPYASFSLWIVS-HRGE-E-FDLRMATIPSCLSKASTVYNPVIYVLMNKQFR
SCMM-KMVC----GKN-IEEDE-AST-SSQVTQVSS------V-----------------
------------------------------------------------------------
--------------------APEK--
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
--------------------MR--------------------------------------
-----------------------KMS--EEEFY------------L-FKNISS-------
---------------V--GPWDGPQY-------------HIAPVWAFYLQAAFMGTVFLI
GFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-VFPVFVASCN-GYFV--FG
RHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNF-RFSSKHALTVVLATWTIGI
GVSIP-PFFG-WS-----RFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSL
ICFSYTQLLRALKAVAAQQQESA-------------------------------------
------------------------------------------------------------
--------------------------------------------TTQKAEREVSRMVVVM
VGSFCVCYVPYAAFAMYMVN-NRNH-G-LDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQ
ACIM-KMVC----GKA-MTDES-DTC-SSQKTEVSTVS-STQV-----------------
------------------------------------------------------------
--------------------GPN---
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------DLAETVIA-STISIVNQVS-GYFV--LG
HPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNV-RFDAKLAIVGIAFSWIWAA
VWTAP-PIFG-WS-----RYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSI
IVLCYLQVWLAIRAVAKQQKESE-------------------------------------
------------------------------------------------------------
--------------------------------------------STQKAEKEVTRMVVVM
VLAFC-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
MAQQWS-LQRLAGRHPQDSYED--------------------------------------
-----------------------STQ--SSIFT------------YTNSNSTR-------
------------------GPFEGPNY-------------HIAPRWVYHLTSVWMIFVVIA
SVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISVVNQVY-GYFV--LG
HPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNV-RFDAKLAIVGIAFSWIWAA
VWTAP-PIFG-WS-----RYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSI
IVLCYLQVWLAIRAVAKQQKESE-------------------------------------
------------------------------------------------------------
--------------------------------------------STQKAEKEVTRMVVVM
VLAFCFCWGPYAFFACFAAA-NPGY-P-FHPLMAALPAFFAKSATIYNPVIYVFMNRQFR
NCIL-QLF-----GKK-VDDGS-ELS-SASKTEVSSV---SSV-----------------
------------------------------------------------------------
--------------------SPA---
>    10== Z68193   1 human Red Opsin <>[]
MAQQWS-LQRLAGRHPQDSYED--------------------------------------
-----------------------STQ--SSIFT------------YTNSNSTR-------
------------------GPFEGPNY-------------HIAPRWVYHLTSVWMIFVVTA
SVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISIVNQVS-GYFV--LG
HPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNV-RFDAKLAIVGIAFSWIWSA
VWTAP-PIFG-WS-----RYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAI
IMLCYLQVWLAIRAVAKQQKESE-------------------------------------
------------------------------------------------------------
--------------------------------------------STQKAEKEVTRMVVVM
IFAYCVCWGPYTFFACFAAA-NPGY-A-FHPLMAALPAYFAKSATIYNPVIYVFMNRQFR
NCIL-QLF-----GKK-VDDGS-ELS-SASKTEVSSV---SSV-----------------
------------------------------------------------------------
--------------------SPA---
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
MTEAWNVAVFAARRSRDD--DD--------------------------------------
-----------------------TTR--GSVFT------------YTNTNNTR-------
------------------GPFEGPNY-------------HIAPRWVYNLVSFFMIIVVIA
SCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-STISVFNQIF-GYFI--LG
HPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGNI-KFDSKLAIIGIVFSWVWAW
GWSAP-PIFG-WS-----RYWPHGLKTSCGPDVFSGSVELGCQSFMLTLMITCCFLPLFI
IIVCYLQVWMAIRAVAAQQKESE-------------------------------------
------------------------------------------------------------
--------------------------------------------STQKAEREVSRMVVVM
IVAFCICWGPYASFVSFAAA-NPGY-A-FHPLAAALPAYFAKSATIYNPVIYVFMNRQFR
NCIM-QLF-----GKK-VDDGS-EAS-TTSRTEVSSVS-NSSV-----------------
------------------------------------------------------------
--------------------APA---
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
MA-AWE-AAFAARRRHEE--ED--------------------------------------
-----------------------TTR--DSVFT------------YTNSNNTR-------
------------------GPFEGPNY-------------HIAPRWVYNLTSVWMIFVVAA
SVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVIA-STISVINQIS-GYFI--LG
HPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGNI-KFDGKLAVAGILFSWLWSC
AWTAP-PIFG-WS-----RYWPHGLKTSCGPDVFSGSSDPGVQSYMVVLMVTCCFFPLAI
IILCYLQVWLAIRAVAAQQKESE-------------------------------------
------------------------------------------------------------
--------------------------------------------STQKAEKEVSRMVVVM
IVAYCFCWGPYTFFACFAAA-NPGY-A-FHPLAAALPAYFAKSATIYNPIIYVFMNRQFR
NCIL-QLF-----GKK-VDDGS-EVS-T-SRTEVSSVS-NSSV-----------------
------------------------------------------------------------
--------------------SPA---
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
------------------------------------------------------------
-------------------------M--SSNSS------------QAPPNGTP-------
------------------GPFDGPQWP------------YQAPQSTYVGVAVLMGTVVAC
ASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-SSVSLSNNIN-GFFV--FG
RRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGDF-QFQRRHAVSGCAFTWGWAL
LWSAP-PLLG-WS-----SYVPEGLRTSCGPNWYTGGSN--NNSYILSLFVTCFVLPLSL
ILFSYTNLLLTLRAAAAQQKEAD-------------------------------------
------------------------------------------------------------
--------------------------------------------TTQRAEREVTRMVIVM
VMAFLLCWLPYSTFALVVAT-HKGI-I-IQPVLASLPSYFSKTATVYNPIIYVFMNKQFQ
SCLL-EMLCCGYQPQR-TGKAS-PGT-PGPHADVTAAGLRNKV-----------------
------------------------------------------------------------
--------------------MPAHPV
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
--------------------MESGNVS---------------------------------
-------------------SSLFGNV--STALR-------------PEARLSA---E---
---TRLLGWNVPPEELRHIPEHWLTY-------------PEPPESMNYLLGTLYIFFTLM
SMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK--TPIFIYNSFH-QGYA--LG
HLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--KMTHGKAIAMIIFIYMYAT
PWVVA-CYTETWG-----RFVPEGYLTSCTFDYLTDN--FDTRLFVACIFFFSFVCPTTM
ITYYYSQIVGHVFSHEKALRDQAKKMNVE------------------SLRS---------
------------------------------------------------------------
----------------------------------------NVDKNKETAEIRIAKAAITI
CFLFFCSWTPYGVMSLIGAF-GDKT-L-LTPGATMIPACACKMVACIDPFVYAISHPRYR
MELQ-KRCPWL--ALNEKAPES-SAV-ASTST---TQE-PQQT-----------------
------------------------------------------------------------
--------------------TAA---
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
--------------------MEYHNVS---------------------------------
-------------------SVL-GNV--SSVLR-------------PDARLSA---E---
---SRLLGWNVPPDELRHIPEHWLIY-------------PEPPESMNYLLGTLYIFFTVI
SMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMIK--TPIFIYNSFH-QGYA--LG
HLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--KMTHGKAIAMIIFIYLYAT
PWVVA-CYTESWG-----RFVPEGYLTSCTFDYLTDN--FDTRLFVACIFFFSFVCPTTM
ITYYYSQIVGHVFSHEKALRDQAKKMNVD------------------SLRS---------
------------------------------------------------------------
----------------------------------------NVDKSKEAAEIRIAKAAITI
CFLFFASWTPYGVMSLIGAF-GDKT-L-LTPGATMIPACTCKMVACIDPFVYAISHPRYR
MELQ-KRCPWL--AISEKAPES-RAA-ISTST---TQE-QQQT-----------------
------------------------------------------------------------
--------------------TAA---
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
--------------------ME--------------------------------------
--------------------PLCNAS--EPPLR-------------PEAR-SSGNGD---
---LQFLGWNVPPDQIQYIPEHWLTQ-------------LEPPASMHYMLGVFYIFLFCA
STVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIF--NSFH-RGFAIYLG
NTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNIIIWLYCT
PWVVL-PLTQFWD-----RFVPEGYLTSCSFDYLSDN--FDTRLFVGTIFFFSFVCPTLM
ILYYYSQIVGHVFSHEKALREQAKKMNVE------------------SLRS---------
------------------------------------------------------------
----------------------------------------NVDKSKETAEIRIAKAAITI
CFLFFVSWTPYGVMSLIGAF-GDKS-L-LTQGATMIPACTCKLVACIDPFVYAISHPRYR
LELQ-KRCPWL--GVNEKSGEI-SSA-QSTTT---QEQ--QQT-----------------
------------------------------------------------------------
--------------------TAA---
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
--------------------MD--------------------------------------
--------------------ALCNAS--EPPLR-------------PEARMSSGSDE---
---LQFLGWNVPPDQIQYIPEHWLTQ-------------LEPPASMHYMLGVFYIFLFFA
STLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIFIYNSFH-RGFA--LG
NTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNIIIWLYCT
PWVVL-PLTQFWD-----RFVPEGYLTSCSFDYLSDN--FDTRLFVGTIFLFSFVVPTLM
ILYYYSQIVGHVFNHEKALREQAKKMNVE------------------SLRS---------
------------------------------------------------------------
----------------------------------------NVDKSKETAEIRIAKAAITI
CFLFFVSWTPYGVMSLIGAF-GDKS-L-LTPGATMIPACTCKLVACIEPFVYAISHPRYR
MELQ-KRCPWL--GVNEKSGEA-SSA-QSTTT---QEQ-TQQT-----------------
------------------------------------------------------------
--------------------SAA---
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
--------------------MT--------------------------------------
-----------------------NAT--GPQMAY-----------YGAASMDFGYPE---
---GVSIVDFVRPEIKPYVHQHWYNY-------------PPVNPMWHYLLGVIYLFLGTV
SIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTTN-VPFFTYNCFSGGVWM--FS
PQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNGP-KLTTGKAVVFALISWVIAI
GCALP-PFFG-WG-----NYILEGILDSCSYDYLTQD--FNTFSYNIFIFVFDYFLPAAI
IVFSYVFIVKAIFAHEAAMRAQAKKMNVS------------------TLRS---------
------------------------------------------------------------
-----------------------------------------NEADAQRAEIRIAKTALVN
VSLWFICWTPYALISLKGVM-GDTS-G-ITPLVSTLPALLAKSCSCYNPFVYAISHPKYR
LAIT-QHLPWF--CVHETETKS-NDD-SQSNS---TVA-Q--------------------
------------------------------------------------------------
--------------------DKA---
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
--------------------MA--------------------------------------
-----------------------NVT--GPQMAF-----------YGSGAATFGYPE---
---GMTVADFVPDRVKHMVLDHWYNY-------------PPVNPMWHYLLGVVYLFLGVI
SIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-FPPFCYNCFSGGRWM--FS
GTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNGP-KLTQGKATFMCGLAWVISV
GWSLP-PFFG-WG-----SYTLEGILDSCSYDYFTRD--MNTITYNICIFIFDFFLPASV
IVFSYVFIVKAIFAHEAAMRAQAKKMNVT------------------NLRS---------
------------------------------------------------------------
-----------------------------------------NEAETQRAEIRIAKTALVN
VSLWFICWTPYAAITIQGLL-GNAE-G-ITPLLTTLPALLAKSCSCYNPFVYAISHPKFR
LAIT-QHLPWF--CVHEKDPND-VEE-NQSSN---TQT-Q--------------------
------------------------------------------------------------
--------------------EKS---
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
--------------------MESF------------------------------------
-------------------AVAAAQL--GPHFA----------------PLS--------
---NGSVVDKVTPDMAHLISPYWNQF-------------PAMDPIWAKILTAYMIMIGMI
SWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV--LG
PMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKM--------
-------------------YVPEGNLTSCGIDYLERD--WNPRSYLIFYSIFVYYIPLFL
ICYSYWFIIAAVSAHEKAMREQAKKMNVK------------------SLRS---------
------------------------------------------------------------
-----------------------------------------SEDAEKSAEGKLAKVALVT
ITLWFMAWTPYLVINCMGLF-KF-E-G-LTPLNTIWGACFAKSAACYNPIVYGISHPKYR
LALK-EKCPCC--VFGKVDDGK-SSD-AQSQA-TASEA-E--------------------
------------------------------------------------------------
--------------------SKA---
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
--------------------MESF------------------------------------
-------------------AVAAAQL--GPHFA----------------PLS--------
---NGSVVDKVTPDMAHLISPYWNQF-------------PAMDPIWAKILTAYMIMIGMI
SWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV--LG
PMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKIAYIWFMSS
IW-CLAPAFG-WS-----RYVPEGNLTSCGIDYLERD--WNPRSYLIFYSIFVYYIPLFL
ICYSYWFIIAAVSAHEKAMREQAKKMNVK------------------SLRS---------
------------------------------------------------------------
-----------------------------------------SEDAEKSAEGKLAKVALVT
ITLWFMAWTPYLVINCMGLF-KF-E-G-LTPLNTIWGACFAKSAACYNPIVYGISHPKYR
LALK-EKCPCC--VFGKVDDGK-SSD-AQSQA-TASEA-E--------------------
------------------------------------------------------------
--------------------SKA---
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
--------------------MDSF------------------------------------
-------------------AAVATQL--GPQFA----------------APS--------
---NGSVVDKVTPDMAHLISPYWDQF-------------PAMDPIWAKILTAYMIIIGMI
SWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV--LG
PMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKIAYIWFMST
IWCCLAPVFG-WS-----RYVPEGNLTSCGIDYLERD--WNPRSYLIFYSIFVYYIPLFL
ICYSYWFIIAAVSAHEKAMREQAKKMNVK------------------SLRS---------
------------------------------------------------------------
-----------------------------------------SEDADKSAEGKLAKVALVT
ISLWFMAWTPYLVINCMGLF-KF-E-G-LTPLNTIWGACFAKSAACYNPIVYGISHPKYR
LALK-EKCPCC--VFGKVDDGK-SSE-AQSQA-TTSEA-E--------------------
------------------------------------------------------------
--------------------SKA---
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
--------------------MERSHLP---------------------------------
-----------------ETPFDLAHS--GPRFQ----------------AQSSG------
---NGSVLDNVLPDMAHLVNPYWSRF-------------APMDPMMSKILGLFTLAIMII
SCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ETWV--LG
PLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGINGT-PMTIKTSIMKILFIWMMAV
FWTVM-PLIG-WS-----AYVPEGNLTACSIDYMTRM--WNPRSYLITYSLFVYYTPLFL
ICYSYWFIIAAVAAHEKAMREQAKKMNVK------------------SLRS---------
------------------------------------------------------------
-----------------------------------------SEDCDKSAEGKLAKVALTT
ISLWFMAWTPYLVICYFGLF-KI-D-G-LTPLTTIWGATFAKTSAVYNPIVYGISHPKYR
IVLK-EKCPMC--VFGNTDEPK-PDA-PASDTETTSEA-D--------------------
------------------------------------------------------------
--------------------SKA---
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
--------------------MERSLLP---------------------------------
-----------------EPPLAMALL--GPRFE----------------AQTGG------
---NRSVLDNVLPDMAPLVNPHWSRF-------------APMDPTMSKILGLFTLVILII
SCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ETWV--LG
PLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGINGT-PMTIKTSIMKIAFIWMMAV
FWTIM-PLIG-WS-----SYVPEGNLTACSIDYMTRQ--WNPRSYLITYSLFVYYTPLFM
ICYSYWFIIATVAAHEKAMRDQAKKMNVK------------------SLRS---------
------------------------------------------------------------
-----------------------------------------SEDCDKSAENKLAKVALTT
ISLWFMAWTPYLIICYFGLF-KI-D-G-LTPLTTIWGATFAKTSAVYNPIVYGISHPNDR
LVLK-EKCPMC--VCGTTDEPK-PDA-PPSDTETTSEA-E--------------------
------------------------------------------------------------
--------------------SKD---
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
--------------------MI--------------------------------------
-----------------------AVS--GPSYE----------------AFSYGGQAR--
-FNNQTVVDKVPPDMLHLIDANWYQY-------------PPLNPMWHGILGFVIGMLGFV
SAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-SPPMVINCYY-ETWV--LG
PLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSGK-PLSINGALIRIIAIWLFSL
GWTIA-PMFG-WN-----RYVPEGNMTACGTDYFNRG--LLSASYLVCYGIWVYFVPLFL
IIYSYWFIIQAVAAHEKNMREQAKKMNVA------------------SLRS---------
------------------------------------------------------------
-----------------------------------------SENQNTSAECKLAKVALMT
ISLWFMAWTPYLVINFSGIF-NL-V-K-ISPLFTIWGSLFAKANAVYNPIVYGISHPKYR
AALF-AKFPSL--AC-AAEPSS-DAV-STTSG-TTTVT-DNEK-----------------
------------------------------------------------------------
--------------------SNA---
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
--------------------M---------------------------------------
------------------------AN--QLSYS----------------SLGWPYQP---
---NASVVDTMPKEMLYMIHEHWYAF-------------PPMNPLWYSILGVAMIILGII
CVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-MPTMTSNCFA-ETWI--LG
PFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAAA-PLTHKKATLLLLFVWIWSG
GWTIL-PFFG-WS-----RYVPEGNLTSCTVDYLTKD--WSSASYVVIYGLAVYFLPLIT
MIYCYFFIVHAVAEHEKQLREQAKKMNVA------------------SLRA---------
------------------------------------------------------------
----------------------------------------NADQQKQSAECRLAKVAMMT
VGLWFMAWTPYLIISWAGVF-SSGT-R-LTPLATIWGSVFAKANSCYNPIVYGISHPRYK
AALY-QRFPSL--ACGSGESGS-DVK-SEASA-TTTME-EKPK-----------------
------------------------------------------------------------
-------------------IPEA---
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
--------------------MV--------------------------------------
-----------------------EST--TL------------------VNQTWWY-----
---NPTVD----------IHPHWAKF-------------DPIPDAVYYSVGIFIGVVGII
GILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLKTISAFM-KKWI--FG
KVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSHRRAFLMIIFVWMWSI
VWSVG-PVFN-WG-----AYVPEGILTSCSFDYLSTD--PSTRSFILCMYFCGFMLPIII
IAFCYFNIVMSVSNHEKEMAAMAKRLNAK------------------ELRK---------
------------------------------------------------------------
-----------------------------------------AQ-AGASAEMKLAKISMVI
ITQFMLSWSPYAIIALLAQF-GPAE-W-VTPYAAELPVLFAKASAIHNPIVYSVSHPKFR
EAIQ-TTFPWLLTCCQFDEKEC-EDA-NDAEE---EVV-ASER--GGESRDAAQMKEMMA
MMQKMQAQQAAYQP---PPPPQGYPPQGYPPQGAYPPPQGYPPQGYPPQGYPPQGYPPQG
APPQVEAPQGAPPQGVDNQAYQA---
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
--------------------MG--------------------------------------
-----------------------RDL--R-------------------DNETWWY-----
---NPSIV----------VHPHWREF-------------DQVPDAVYYSLGIFIGICGII
GCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFL-KKWI--FG
FAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSV
LWAIG-PIFG-WG-----AYTLEGVLCNCSFDYISRD--STTRSNILCMFILGFFGPILI
IFFCYFNIVMSVSNHEKEMAAMAKRLNAK------------------ELRK---------
------------------------------------------------------------
-----------------------------------------AQ-AGANAEMRLAKISIVI
VSQFLLSWSPYAVVALLAQF-GPLE-W-VTPYAAQLPVMFAKASAIHNPMIYSVSHPKFR
EAIS-QTFPWVLTCCQFDDKET-EDD-KDAET---EIP-AGESSDAAPSADAAQMKEMMA
MMQKMQQQQAAYPPQGYAPPPQGYPPQGYPPQGY--PPQGYPPQGYPP---PPQGAPPQG
APP------AAPPQGVDNQAYQA---
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
M-------------------MDVNSSG-----------RPDLYGHLRSFLLPEVGRGLPD
LSPDG------------GADPVAGS----------------------------WAPHLLS
---EVTAS----------PAPTW---DAPPDNASGCGEQINYGRVEKVVIGSILTLITLL
TIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI--FG
HFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSA
SITLP-PLFG-WA-----QNVNDDKVCLISQDF----------GYTIYSTAVAFYIPMSV
MLFMYYQIYKAARKSAAKHKF--------------PGFPRVEPDSVIALNG---------
-------------------------------------------IVKLQKE----------
--------VEECAN------------------LSRLLKHERKNISIFKREQKAATTLGII
VGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLR
TTYR-SLLQ----CQYRNINRKLSAA-GMHEA--LKLA-ERPE----RPEFVLQNADYCR
------------------------------------------------------------
--------------------KKGHDS
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
------------------------------------------------------------
------------------------------------------------------MPHLLS
GFLEVTAS----------PAPTW---DAPPDNVSGCGEQINYGRVEKVVIGSILTLITLL
TIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI--FG
HFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSA
SITLP-PLFG-WA-----QNVNDDKVCLISQDF----------GYTIYSTAVAFYIPMSV
MLFMYYQIYKAARKSAAKHKF--------------PGFPRVQPESVISLNG---------
-------------------------------------------VVKLQKE----------
--------VEECAN------------------LSRLLKHERKNISIFKREQKAATTLGII
VGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLR
PTSR-SLLQ----CQYRNINRKLSAA-GMHEA--LKLA-ERPE----RSEFVLQNSDHCG
------------------------------------------------------------
--------------------KKGHDT
>    31=p A47425 serotonin receptor 5HT-7 - rat
------------------------------------------------------------
------------------------------------------------------MPHLLS
GFLEVTAS----------PAPTW---DAPPDNVSGCGEQINYGRVEKVVIGSILTLITLL
TIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI--FG
HFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSA
SITLP-PLFG-WA-----QNVNDDKVCLISQDF----------GYTIYSTAVAFYIPMSV
MLFMYYQIYKAARKSAAKHKF--------------PGFPRVQPESVISLNG---------
-------------------------------------------VVKLQKE----------
--------VEECAN------------------LSRLLKHERKNISIFKREQKAATTLGII
VGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLR
TTYR-SLLQ----CQYRNINRKLSAA-GMHEA--LKLA-ERPE----RSEFVLQNSDHCG
------------------------------------------------------------
--------------------KKGHDT
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
--------------------MDVLSPG---------------------------------
-----------------------------------------------QGNNT--------
---TSPPAPF-------ETGGNTTGISD-------------VTVSYQVITSLLLGTLIFC
AVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NKWT--LG
QVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGF
LISIP-PMLG-WRTPEDRSDPD---ACTISKDH----------GYTIYSTFGAFYIPLLL
MLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKK-----SVNG--ESGSRNW
RLGVESKAGGALCANGAVRQGDDGAAL--EVIEVHRVGNSKEHLPLPSEAGPTPCAPAS-
-----------------FERKNERNA-------------EAKRKMALARERKTVKTLGII
MGTFILCWLPFFIVALVLPF-CESSCH-MPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQ
NAFK-KIIK----CKFCR------------------------------------------
------------------------------------------------------------
-------------------------Q
>    33=p A35181 serotonin receptor class 1A - rat
--------------------MDVFSFG---------------------------------
-----------------------------------------------QGNNT--------
---TASQEPF-------GTGGNVTSISD-------------VTFSYQVITSLLLGTLIFC
AVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NKWT--LG
QVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGF
LISIP-PMLG-WRTPEDRSDPD---ACTISKDH----------GYTIYSTFGAFYIPLLL
MLVLYGRIFRAARFRIRKTVRKVEKKGAGTSLGTSSAPPPKK-----SLNG--QPGSGDW
RRCAENRAVGTPCTNGAVRQGDDEATL--EVIEVHRVGNSKEHLPLPSESGSNSYAPAC-
-----------------LERKNERNA-------------EAKRKMALARERKTVKTLGII
MGTFILCWLPFFIVALVLPF-CESSCH-MPALLGAIINWLGYSNSLLNPVIYAYFNKDFQ
NAFK-KIIK----CKFCR------------------------------------------
------------------------------------------------------------
-------------------------R
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
--------------------MANFTFGDLALDVARMGGLASTPSGLRS-----TGLTTPG
LSPTGLVTSDFNDSYGLTGQFINGSH--SSRSRD-----------NASANDT--------
---SATNM----------TDDRYWSLTV-------------YSHEHLVLTSVILGLFVLC
CIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KVWF--LH
SEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMVVWIVAL
FISIP-PLFG-WRDPNN--DPDKTGTCIISQDK----------GYTIFSTVGAFYLPMLV
MMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNSPDSTTE
KKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSSSERLKQIQIETAEAFANGCA
EEASIAMLERQCNNGKKISSNDTPYS-------------RTREKLELKRERKAARTLAII
TGAFLICWLPFFIIALIGPF-VDPE-G-IPPFARSFVLWLGYFNSLLNPIIYTIFSPEFR
SAFQ-KILF----GKYRR----GH------------------------------------
------------------------------------------------------------
-------------------------R
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
--------------------MANFTFGDLALDVARMGGLASTPSGLRS-----TGLTTPG
LSPTGLVTSDFNDSYGLTGQFINGSH--SSRSRD-----------NASANDT--------
---SATNM----------TDDRYWSLTV-------------YSHEHLVLTSVILGLFVLC
CIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KVWF--LH
SEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMVVWIVAL
FISIP-PLFG-WRDPNN--DPDKTGTCIISQDK----------GYTIFSTVGAFYLPMLV
MMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNSPDSTTE
KKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSSSERLKQIQIETAEAFANGCA
EEASIAMLERQCNNGKKISSNDTPYS-------------RTREKLELKRERKAARTLAII
TGAFLICWLPFFIIALIGPF-VDPE-G-IPPFARSFVLWLGYFNSLLNPIIYTIFSPEFR
SAFQ-KILF----GKYRR----GH------------------------------------
------------------------------------------------------------
-------------------------R
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
--------------------ME--------------------------------------
-----------------------GAE--GQEELDWEALYLRLPLQNCSWNSTGWEPN---
--WNVTVV----------PNTTWWQASAPFDT--------PAALVRAAAKAVVLGLLILA
TVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACLV-MPLGAVYEVV-QRWT--LG
PELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIHASTAKRVGMMIACVWTVSF
FVCIA-QLLG-WKDPDWNQRVSEDLRCVVSQDV----------GYQIFATASSFYVPVLI
ILILYWRIYQTARKRIRR------RRGATARGGVGPPPVPAGGALV-AGGG---------
-------------------SGGIAAAV---------VAVIGRPLPTISETTTTGFTNVSS
NNTSPE--KQSCANGLEADPPTTGYGAVAAAYYPSLVRRKPKEAADSKRERKAAKTLAII
TGAFVACWLPFFVLAILVPT-CD--CE-VSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFR
HAFQ-RLLC----GRRVRR-RRAP------------------------------------
------------------------------------------------------------
-------------------------Q
