>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
-------------------------------MNGTE--GDNFY--------------VP-
----FSNKTG----------------LARSPYEYPQY-------YLAEPW---------K
YSALAAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-FTVTM
YTSMN-GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGNF-RFGNT
HAIMGVAFTWIMALAC-AAPPLVG-WS-----RYIPEGMQCSCGPDYYTLNPNFNNESYV
VYMFVVHFLVPFVIIFFCYGRLLCTVKEAAAA----------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------QQ-ESASTQKAEKEVTRMVVLMVIGFLVCWVPYASVAFYIFTHQG
S---DFGATFMTLPAFFAKSSALYNPVIYILMNKQFRNCMITTLCC--------------
----------GKNPLGDDE-SGA-STSK-TEVSSVS-TSPVSPA----------------
------------------------------------------------------------
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
-------------------------------MNGTE--GPNFY--------------VP-
----FSNITG----------------VVRSPFEQPQY-------YLAEPW---------Q
FSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTTL
YTSLH-GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSNF-RFGEN
HAIMGVAFTWVMALAC-AAPPLVG-WS-----RYIPEGMQCSCGIDYYTLKPEVNNESFV
IYMFVVHFTIPMIVIFFCYGQLVFTVKEAAAQ----------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------QQ-ESATTQKAEKEVTRMVIIMVIFFLICWLPYASVAMYIFTHQG
S---NFGPIFMTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSLCC--------------
----------GKNPLGDDE-ASA-TASK-TE------TSQVAPA----------------
------------------------------------------------------------
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
-------------------------------MNGTE--GINFY--------------VP-
----MSNKTG----------------VVRSPFEYPQY-------YLAEPW---------K
YRLVCCYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-FTVTF
YTAWN-GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGNF-RFSAT
HAMMGIAFTWVMAFSC-AAPPLFG-WS-----RYMPEGMQCSCGPDYYTHNPDYHNESYV
LYMFVIHFIIPVVVIFFSYGRLICKVREAAAQ----------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------QQ-ESATTQKAEKEVTRMVILMVLGFMLAWTPYAVVAFWIFTNKG
A---DFTATLMAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTICC--------------
----------GKNPFGDEDVSSTVSQSK-TEVSSVS-SSQVSPA----------------
------------------------------------------------------------
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
-------------------------------MNGTE--GKNFY--------------VP-
----MSNRTG----------------LVRSPFEYPQY-------YLAEPW---------Q
FKILALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-FTVTF
YTAIN-GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGSF-KFSSS
HAFAGIAFTWVMALAC-AAPPLFG-WS-----RYIPEGMQCSCGPDYYTLNPDYNNESYV
IYMFVCHFILPVAVIFFTYGRLVCTVKAAAAQ----------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------QQ-DSASTQKAEREVTKMVILMVFGFLIAWTPYATVAAWIFFNKG
A---DFSAKFMAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTIFC--------------
----------GKNPLGDDE-SSTVSTSK-TEVSSVS-PA---------------------
------------------------------------------------------------
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
-------------------------------MNGTE--GNNFY--------------VP-
----LSNRTG----------------LVRSPFEYPQY-------YLAEPW---------Q
FKLLAVYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-FTVTF
YTAIN-GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGSF-KFSST
HASAGIAFTWVMAMAC-AAPPLVG-WS-----RYIPEGIQCSCGPDYYTLNPEYNNESYV
LYMFICHFILPVTIIFFTYGRLVCTVKAAAAQ----------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------QQ-DSASTQKAEREVTKMVILMVLGFLVAWTPYATVAAWIFFNKG
A---AFSAQFMAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTLFC--------------
----------GKNPLGDEE-SSTVSTSK-TEVSSVS-PA---------------------
------------------------------------------------------------
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
-------------------------------MKQVPEFHEDFY--------------IPI
PLD-INNLSA------------------YSPFLVPQD-------HLGNQG---------I
FMAMSVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-SPLSF
YSFFN-RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGNF-TFKTP
HAIAGCILPWISALAA-SLPPLFG-WS-----RYIPEGLQCSCGPDWYTTNNKYNNESYV
MFLFCFCFAVPFGTIVFCYGQLLITLKLAAKA----------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------QA-DSASTQKAEREVTKMVVVMVLGFLVCWAPYASFSLWIVSHRG
E---EFDLRMATIPSCLSKASTVYNPVIYVLMNKQFRSCMMKMVC---------------
----------GKN-IEEDE-AST-SSQV-TQVSSVA-PEK--------------------
------------------------------------------------------------
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
-------------------------------MRKMS--EEEFY--------------L--
----FKNISS------------------VGPWDGPQY-------HIAPVW---------A
FYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-VFPVF
VASCN-GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNF-RFSSK
HALTVVLATWTIGIGV-SIPPFFG-WS-----RFIPEGLQCSCGPDWYTVGTKYRSESYT
WFLFIFCFIVPLSLICFSYTQLLRALKAVAAQ----------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------QQ-ESATTQKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRN
H---GLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIMKMVC---------------
----------GKA-MTDES-DTC-SSQK-TEVSTVS-STQVGPN----------------
------------------------------------------------------------
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------DLAETVIA-STISI
VNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNV-RFDAK
LAIVGIAFSWIWAAVW-TAPPIFG-WS-----RYWPHGLKTSCGPDVFSGSSYPGVQSYM
IVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQ----------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------QK-ESESTQKAEKEVTRMVVVMVLAFC------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
MAQQWS-LQRLAGRHPQDS-----------YEDSTQ--SSIFT--------------YT-
----NSNST-------------------RGPFEGPNY-------HIAPRW---------V
YHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISV
VNQVY-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNV-RFDAK
LAIVGIAFSWIWAAVW-TAPPIFG-WS-----RYWPHGLKTSCGPDVFSGSSYPGVQSYM
IVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQ----------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------QK-ESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPG
Y---PFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLF----------------
----------GKK-VDDGS-ELS-SASK-TEVSSV---SSVSPA----------------
------------------------------------------------------------
>    10== Z68193   1 human Red Opsin <>[]
MAQQWS-LQRLAGRHPQDS-----------YEDSTQ--SSIFT--------------YT-
----NSNST-------------------RGPFEGPNY-------HIAPRW---------V
YHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISI
VNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNV-RFDAK
LAIVGIAFSWIWSAVW-TAPPIFG-WS-----RYWPHGLKTSCGPDVFSGSSYPGVQSYM
IVLMVTCCIIPLAIIMLCYLQVWLAIRAVAKQ----------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------QK-ESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPG
Y---AFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLF----------------
----------GKK-VDDGS-ELS-SASK-TEVSSV---SSVSPA----------------
------------------------------------------------------------
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
MTEAWNVAVFAARRSRDD-------------DDTTR--GSVFT--------------YT-
----NTNNT-------------------RGPFEGPNY-------HIAPRW---------V
YNLVSFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-STISV
FNQIF-GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGNI-KFDSK
LAIIGIVFSWVWAWGW-SAPPIFG-WS-----RYWPHGLKTSCGPDVFSGSVELGCQSFM
LTLMITCCFLPLFIIIVCYLQVWMAIRAVAAQ----------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------QK-ESESTQKAEREVSRMVVVMIVAFCICWGPYASFVSFAAANPG
Y---AFHPLAAALPAYFAKSATIYNPVIYVFMNRQFRNCIMQLF----------------
----------GKK-VDDGS-EAS-TTSR-TEVSSVS-NSSVAPA----------------
------------------------------------------------------------
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
M-AAWE-AAFAARRRHEE-------------EDTTR--DSVFT--------------YT-
----NSNNT-------------------RGPFEGPNY-------HIAPRW---------V
YNLTSVWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVIA-STISV
INQIS-GYFI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGNI-KFDGK
LAVAGILFSWLWSCAW-TAPPIFG-WS-----RYWPHGLKTSCGPDVFSGSSDPGVQSYM
VVLMVTCCFFPLAIIILCYLQVWLAIRAVAAQ----------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------QK-ESESTQKAEKEVSRMVVVMIVAYCFCWGPYTFFACFAAANPG
Y---AFHPLAAALPAYFAKSATIYNPIIYVFMNRQFRNCILQLF----------------
----------GKK-VDDGS-EVS--TSR-TEVSSVS-NSSVSPA----------------
------------------------------------------------------------
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
-----------------------------------M--SSNSS--------------QA-
----PPNGT-------------------PGPFDGPQW------PYQAPQS---------T
YVGVAVLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-SSVSL
SNNIN-GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGDF-QFQRR
HAVSGCAFTWGWALLW-SAPPLLG-WS-----SYVPEGLRTSCGPNWYTGGSN--NNSYI
LSLFVTCFVLPLSLILFSYTNLLLTLRAAAAQ----------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------QK-EADTTQRAEREVTRMVIVMVMAFLLCWLPYSTFALVVATHKG
I---IIQPVLASLPSYFSKTATVYNPIIYVFMNKQFQSCLLEMLCCGY------------
---------QPQR-TGKAS-PGT-PGPH-ADVTAAGLRNKVMPAH---------------
---------------------------------------------PV-------------
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
MESGN-------------------VSSS---LFGNV--STALRPEA--RLSA---E----
------TRLL----------------GWNVPPEELR--------HIPEHWLTYPEPPESM
NYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMM-VK-TPIFI
YNSFH-QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--KMTHG
KAIAMIIFIYMYATPW-VVACYTETWG-----RFVPEGYLTSCTFDYLTDN--FDTRLFV
ACIFFFSFVCPTTMITYYYSQIVGHVFSHEKA----------------------------
----------------------------LRDQAKKMNVESL-------------------
------------------------------------------------------------
---------------RSNVDKNKETAEIRIAKAAITICFLFFCSWTPYGVMSLIGAFGDK
T---LLTPGATMIPACACKMVACIDPFVYAISHPRYRMELQKRCPWLA------------
---------LNEK-APESS-AVA-STST-TQEPQ---QTTAA------------------
------------------------------------------------------------
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
MEYHN-------------------VSS----VLGNV--SSVLRPDA--RLSA---E----
------SRLL----------------GWNVPPDELR--------HIPEHWLIYPEPPESM
NYLLGTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMM-IK-TPIFI
YNSFH-QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--KMTHG
KAIAMIIFIYLYATPW-VVACYTESWG-----RFVPEGYLTSCTFDYLTDN--FDTRLFV
ACIFFFSFVCPTTMITYYYSQIVGHVFSHEKA----------------------------
----------------------------LRDQAKKMNVDSL-------------------
------------------------------------------------------------
---------------RSNVDKSKEAAEIRIAKAAITICFLFFASWTPYGVMSLIGAFGDK
T---LLTPGATMIPACTCKMVACIDPFVYAISHPRYRMELQKRCPWLA------------
---------ISEK-APESR-AAI-STST-TQEQQ---QTTAA------------------
------------------------------------------------------------
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
MEP----------------------------LCNAS--EPPLRPEA--R-SSGNGD----
------LQFL----------------GWNVPPDQIQ--------YIPEHWLTQLEPPASM
HYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMC-LK-APIF-
-NSFH-RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFT
KAVIMNIIIWLYCTPW-VVLPLTQFWD-----RFVPEGYLTSCSFDYLSDN--FDTRLFV
GTIFFFSFVCPTLMILYYYSQIVGHVFSHEKA----------------------------
----------------------------LREQAKKMNVESL-------------------
------------------------------------------------------------
---------------RSNVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDK
S---LLTQGATMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWLG------------
---------VNEK-SGEIS-SAQ-STTT-QEQQQ---TTAA-------------------
------------------------------------------------------------
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
MDA----------------------------LCNAS--EPPLRPEA--RMSSGSDE----
------LQFL----------------GWNVPPDQIQ--------YIPEHWLTQLEPPASM
HYMLGVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMC-LK-APIFI
YNSFH-RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFT
KAVIMNIIIWLYCTPW-VVLPLTQFWD-----RFVPEGYLTSCSFDYLSDN--FDTRLFV
GTIFLFSFVVPTLMILYYYSQIVGHVFNHEKA----------------------------
----------------------------LREQAKKMNVESL-------------------
------------------------------------------------------------
---------------RSNVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDK
S---LLTPGATMIPACTCKLVACIEPFVYAISHPRYRMELQKRCPWLG------------
---------VNEK-SGEAS-SAQ-STTT-QEQTQ---QTSAA------------------
------------------------------------------------------------
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
-------------------------------MTNAT--GPQMAYYGAASMDFGYPE----
------GVSI----------------VDFVRPEIKP--------YVHQHWYNYPPVNPMW
HYLLGVIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTTN-VPFFT
YNCFSGGVWM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNGP-KLTTG
KAVVFALISWVIAIGC-ALPPFFG-WG-----NYILEGILDSCSYDYLTQD--FNTFSYN
IFIFVFDYFLPAAIIVFSYVFIVKAIFAHEAA----------------------------
----------------------------MRAQAKKMNVSTL-------------------
------------------------------------------------------------
---------------RS-NEADAQRAEIRIAKTALVNVSLWFICWTPYALISLKGVMGDT
S---GITPLVSTLPALLAKSCSCYNPFVYAISHPKYRLAITQHLPWFC------------
---------VHET-ETKSN-DDS-QSNS-TVAQD---KA---------------------
------------------------------------------------------------
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
-------------------------------MANVT--GPQMAFYGSGAATFGYPE----
------GMTV----------------ADFVPDRVKH--------MVLDHWYNYPPVNPMW
HYLLGVVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-FPPFC
YNCFSGGRWM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNGP-KLTQG
KATFMCGLAWVISVGW-SLPPFFG-WG-----SYTLEGILDSCSYDYFTRD--MNTITYN
ICIFIFDFFLPASVIVFSYVFIVKAIFAHEAA----------------------------
----------------------------MRAQAKKMNVTNL-------------------
------------------------------------------------------------
---------------RS-NEAETQRAEIRIAKTALVNVSLWFICWTPYAAITIQGLLGNA
E---GITPLLTTLPALLAKSCSCYNPFVYAISHPKFRLAITQHLPWFC------------
---------VHEK-DPNDV-EEN-QSSN-TQTQE---KS---------------------
------------------------------------------------------------
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
ME------------------------SFAV-AAAQL--GPHFAPLS--------------
------NGSV----------------VDKVTPDMAH--------LISPYWNQFPAMDPIW
AKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMG
INLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIP
LALGKM---------------------------YVPEGNLTSCGIDYLERD--WNPRSYL
IFYSIFVYYIPLFLICYSYWFIIAAVSAHEKA----------------------------
----------------------------MREQAKKMNVKSL-------------------
------------------------------------------------------------
---------------RS-SEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLFKF-
E---GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCV------------
---------FGKV-DDGKS-SDA-QSQA-TASEA---ESKA-------------------
------------------------------------------------------------
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
ME------------------------SFAV-AAAQL--GPHFAPLS--------------
------NGSV----------------VDKVTPDMAH--------LISPYWNQFPAMDPIW
AKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMG
INLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIP
LALGKIAYIWFMSSIW-CLAPAFG-WS-----RYVPEGNLTSCGIDYLERD--WNPRSYL
IFYSIFVYYIPLFLICYSYWFIIAAVSAHEKA----------------------------
----------------------------MREQAKKMNVKSL-------------------
------------------------------------------------------------
---------------RS-SEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLFKF-
E---GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCV------------
---------FGKV-DDGKS-SDA-QSQA-TASEA---ESKA-------------------
------------------------------------------------------------
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
MD------------------------SFAA-VATQL--GPQFAAPS--------------
------NGSV----------------VDKVTPDMAH--------LISPYWDQFPAMDPIW
AKILTAYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMG
INLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIP
LALGKIAYIWFMSTIWCCLAPVFG-WS-----RYVPEGNLTSCGIDYLERD--WNPRSYL
IFYSIFVYYIPLFLICYSYWFIIAAVSAHEKA----------------------------
----------------------------MREQAKKMNVKSL-------------------
------------------------------------------------------------
---------------RS-SEDADKSAEGKLAKVALVTISLWFMAWTPYLVINCMGLFKF-
E---GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCV------------
---------FGKV-DDGKS-SEA-QSQA-TTSEA---ESKA-------------------
------------------------------------------------------------
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
MERSH-------------------LPETPF-DLAHS--GPRFQAQS-----SG-------
------NGSV----------------LDNVLPDMAH--------LVNPYWSRFAPMDPMM
SKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMI
INFYY-ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGINGT-PMTIK
TSIMKILFIWMMAVFW-TVMPLIG-WS-----AYVPEGNLTACSIDYMTRM--WNPRSYL
ITYSLFVYYTPLFLICYSYWFIIAAVAAHEKA----------------------------
----------------------------MREQAKKMNVKSL-------------------
------------------------------------------------------------
---------------RS-SEDCDKSAEGKLAKVALTTISLWFMAWTPYLVICYFGLFKI-
D---GLTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMCV------------
---------FGNT-DEPKP-DAP-ASDTETTSEA---DSKA-------------------
------------------------------------------------------------
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
MERSL-------------------LPEPPL-AMALL--GPRFEAQT-----GG-------
------NRSV----------------LDNVLPDMAP--------LVNPHWSRFAPMDPTM
SKILGLFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMI
INFYY-ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGINGT-PMTIK
TSIMKIAFIWMMAVFW-TIMPLIG-WS-----SYVPEGNLTACSIDYMTRQ--WNPRSYL
ITYSLFVYYTPLFMICYSYWFIIATVAAHEKA----------------------------
----------------------------MRDQAKKMNVKSL-------------------
------------------------------------------------------------
---------------RS-SEDCDKSAENKLAKVALTTISLWFMAWTPYLIICYFGLFKI-
D---GLTPLTTIWGATFAKTSAVYNPIVYGISHPNDRLVLKEKCPMCV------------
---------CGTT-DEPKP-DAP-PSDTETTSEA---ESKD-------------------
------------------------------------------------------------
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
-------------------------------MIAVS--GPSYEAFS-----YGGQA----
---RFNNQTV----------------VDKVPPDMLH--------LIDANWYQYPPLNPMW
HGILGFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-SPPMV
INCYY-ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSGK-PLSIN
GALIRIIAIWLFSLGW-TIAPMFG-WN-----RYVPEGNMTACGTDYFNRG--LLSASYL
VCYGIWVYFVPLFLIIYSYWFIIQAVAAHEKN----------------------------
----------------------------MREQAKKMNVASL-------------------
------------------------------------------------------------
---------------RS-SENQNTSAECKLAKVALMTISLWFMAWTPYLVINFSGIFNL-
V---KISPLFTIWGSLFAKANAVYNPIVYGISHPKYRAALFAKFPSLA------------
---------CAA--EPSSD-AVS-TTSG-TTTVT---DNEKSNA----------------
------------------------------------------------------------
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
-------------------------------MANQL----SYSSLG-----WPYQP----
------NASV----------------VDTMPKEMLY--------MIHEHWYAFPPMNPLW
YSILGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-MPTMT
SNCFA-ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAAA-PLTHK
KATLLLLFVWIWSGGW-TILPFFG-WS-----RYVPEGNLTSCTVDYLTKD--WSSASYV
VIYGLAVYFLPLITMIYCYFFIVHAVAEHEKQ----------------------------
----------------------------LREQAKKMNVASL-------------------
------------------------------------------------------------
---------------RANADQQKQSAECRLAKVAMMTVGLWFMAWTPYLIISWAGVFSSG
T---RLTPLATIWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPSLA------------
---------CGSG-ESGSD-VKS-EASA-TTTME---EKPKIPEA---------------
------------------------------------------------------------
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
M------------------------------VESTTLVNQTWWY----------------
------NPTV----------------------------------DIHPHWAKFDPIPDAV
YYSVGIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLKT
ISAFM-KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSHR
RAFLMIIFVWMWSIVW-SVGPVFN-WG-----AYVPEGILTSCSFDYLSTD--PSTRSFI
LCMYFCGFMLPIIIIAFCYFNIVMSVSNHEKE----------------------------
----------------------------MAAMAKRLNAKEL-------------------
------------------------------------------------------------
---------------RK--AQAGASAEMKLAKISMVIITQFMLSWSPYAIIALLAQFGPA
E---WVTPYAAELPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCCQFDEKECED
ANDAEEEVVASER---GGE-SRD-AAQM-KEMMAMMQKMQAQQAAYQP---PPPPQGYPP
QGYPPQGAYPPPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVD---NQAYQA
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
-------------------------------MGRDLRDNETWWY----------------
------NPSI----------------------------------VVHPHWREFDQVPDAV
YYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMT
ISCFL-KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHR
RAFIMIIFVWLWSVLW-AIGPIFG-WG-----AYTLEGVLCNCSFDYISRD--STTRSNI
LCMFILGFFGPILIIFFCYFNIVMSVSNHEKE----------------------------
----------------------------MAAMAKRLNAKEL-------------------
------------------------------------------------------------
---------------RK--AQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPL
E---WVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETED
DKDAETEIPAGES-SDAAP-SAD-AAQM-KEMMAMMQKMQQQQAAYPPQGYAPPPQGYPP
QGYPPQGY--PPQGYPPQGYPP---PPQGAPPQGAPP------AAPPQGVD---NQAYQA
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
M-----MDVNSSGRPDLYGHLRSFL------LPEVGRGLPDLSPDG--GADPVAGSWAPH
LLS---EVTASPAPTW------------DAPPDNAS--------GCGE----QINYGRVE
KVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVS
VTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGK
CMAKMILSVWLLSASI-TLPPLFG-WA-----QNVNDDKVCLISQDF----------GYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKF-------------------------
--------PGF-----------------PRVEPDSV------------------------
---------------I---ALNGIVK-----LQKEV---EECAN----------------
--LSRLLK------HER-KNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICG
TSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQ---------------
----------CQY-RNINR-KLS-AAGM-HEALKLA-ERPERPEF---------------
---------------------------------------------VLQNADYCRKKGHDS
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
---------------------------------------------------------MPH
LLSGFLEVTASPAPTW------------DAPPDNVS--------GCGE----QINYGRVE
KVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVS
VTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGK
CMAKMILSVWLLSASI-TLPPLFG-WA-----QNVNDDKVCLISQDF----------GYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKF-------------------------
--------PGF-----------------PRVQPESV------------------------
---------------I---SLNGVVK-----LQKEV---EECAN----------------
--LSRLLK------HER-KNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICG
TSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRPTSRSLLQ---------------
----------CQY-RNINR-KLS-AAGM-HEALKLA-ERPERSEF---------------
---------------------------------------------VLQNSDHCGKKGHDT
>    31=p A47425 serotonin receptor 5HT-7 - rat
---------------------------------------------------------MPH
LLSGFLEVTASPAPTW------------DAPPDNVS--------GCGE----QINYGRVE
KVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVS
VTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGK
CMAKMILSVWLLSASI-TLPPLFG-WA-----QNVNDDKVCLISQDF----------GYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKF-------------------------
--------PGF-----------------PRVQPESV------------------------
---------------I---SLNGVVK-----LQKEV---EECAN----------------
--LSRLLK------HER-KNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICG
TSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQ---------------
----------CQY-RNINR-KLS-AAGM-HEALKLA-ERPERSEF---------------
---------------------------------------------VLQNSDHCGKKGHDT
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
M------DVLSPGQ-----------------GNNTTSPPAPFETGG--------------
------NTTGISDVTV------------------------------------------SY
QVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAA
LYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPR
RAAALISLTWLIGFLI-SIPPMLG-WRTP---EDRSDPDACTISKDH----------GYT
IYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK----------------------------
-----------TVKKVEKTGADTRHGASPAPQPKKS-----------VNGESGS------
----RNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAG--PT
PCAPASFERKNERNAEA-KRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCES
S-C-HMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIK---------------
----------CKF-CRQ-------------------------------------------
------------------------------------------------------------
>    33=p A35181 serotonin receptor class 1A - rat
M------DVFSFGQ-----------------GNNTTASQEPFGTGG--------------
------NVTSISDVTF------------------------------------------SY
QVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAA
LYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPR
RAAALISLTWLIGFLI-SIPPMLG-WRTP---EDRSDPDACTISKDH----------GYT
IYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK----------------------------
-----------TVRKVEKKGAGTSLGTSSAPPPKKS-----------LNGQPGS------
----GDWRRCAENRAVGTPCTNGAVRQGDDEATLEVIEVHRVGNSKEHLPLPSESG--SN
SYAPACLERKNERNAEA-KRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCES
S-C-HMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIK---------------
----------CKF-CRR-------------------------------------------
------------------------------------------------------------
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
M------ANFTFGDLALDVARMGGLASTPSGLRSTGLTTPGLSPTG--------------
------LVTSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATNMTDDRYWSLTVYSHEH
LVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSV
VSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSAR
RILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK----------GYT
IFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVV
SDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSS------
----SERLKQIQIET-----AEAFANGCAEEASIAMLE-RQCNNGKK-------------
------ISSNDTPYSRT-REKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPFVDP
E---GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILF---------------
----------GKY-RRGHR-----------------------------------------
------------------------------------------------------------
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
M------ANFTFGDLALDVARMGGLASTPSGLRSTGLTTPGLSPTG--------------
------LVTSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATNMTDDRYWSLTVYSHEH
LVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSV
VSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSAR
RILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK----------GYT
IFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVV
SDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSS------
----SERLKQIQIET-----AEAFANGCAEEASIAMLE-RQCNNGKK-------------
------ISSNDTPYSRT-REKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPFVDP
E---GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILF---------------
----------GKY-RRGHR-----------------------------------------
------------------------------------------------------------
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
MEGAE-------GQEELDWEAL--YLRLP--LQNCSWNSTGWEPNW--------------
------NVTVVPNTTW---------WQASAPFDTPAA--------------------LVR
AAAKAVVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACLV-MPLGA
VYEVV-QRWT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIHASTAK
RVGMMIACVWTVSFFV-CIAQLLG-WKDPDWNQRVSEDLRCVVSQDV----------GYQ
IFATASSFYVPVLIILILYWRIYQTARKRIRR----------------------------
-----------------RRGATARGGVGPPPVPAGG-----A----LVAGGGSGGIAAAV
VAVIGRPLPTISETT-----TTGFTNVSSNNTSPEK---QSCANGLEADPPTTGYGAVAA
AYYPSLVR------RKP-KEAADSKRERKAAKTLAIITGAFVACWLPFFVLAILVPTCDC
E----VSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRLLC---------------
----------GRR-VRRRR----------------------APQ----------------
------------------------------------------------------------
