>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
-------------------MNGTEG-----------------------------------
------------DNFYVP----FSNKTGLA--------RSPYEYPQ--------------
-----Y-YLAEPW---------KYSALAAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLN
YILLNLAMANLFMVLFGF-TVTMYTSMN-GYFV--FGPTMCSIEGFFATLGGEVALWSLV
VLAIERYIVICKPMGNF-RFGNTHAIMGVAFTWIMALAC-AAPPLVG-W-----SRYIPE
GMQCSCGPDYYTLNPNFNNESYVVYMFVVHFLVPFVIIFFCYGRLLCTVKEAAAA-----
------------------------------------------------------------
------------------------------------------------------------
-------------------------------QQESASTQK------AEKEVTRMVVLMVI
GFLVCWVPYASVAFYI---FTHQGSDFGATFMTLPAFFAKSSALYNPVIYILMNKQFRNC
MITTLCCGKNPLGDDE-SGA-STSKTEVSSV-STSPVSPA--------------------
------------------------------------------------------------
---------------
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
-------------------MNGTEG-----------------------------------
------------PNFYVP----FSNITGVV--------RSPFEQPQ--------------
-----Y-YLAEPW---------QFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLN
YILLNLAVADLFMVFGGF-TTTLYTSLH-GYFV--FGPTGCNLEGFFATLGGEIGLWSLV
VLAIERYVVVCKPMSNF-RFGENHAIMGVAFTWVMALAC-AAPPLVG-W-----SRYIPE
GMQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIVIFFCYGQLVFTVKEAAAQ-----
------------------------------------------------------------
------------------------------------------------------------
-------------------------------QQESATTQK------AEKEVTRMVIIMVI
FFLICWLPYASVAMYI---FTHQGSNFGPIFMTLPAFFAKTASIYNPIIYIMMNKQFRNC
MLTSLCCGKNPLGDDE-ASA-TASKTE------TSQVAPA--------------------
------------------------------------------------------------
---------------
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
-------------------MNGTEG-----------------------------------
------------INFYVP----MSNKTGVV--------RSPFEYPQ--------------
-----Y-YLAEPW---------KYRLVCCYIFFLISTGLPINLLTLLVTFKHKKLRQPLN
YILVNLAVADLFMACFGF-TVTFYTAWN-GYFV--FGPVGCAVEGFFATLGGQVALWSLV
VLAIERYIVVCKPMGNF-RFSATHAMMGIAFTWVMAFSC-AAPPLFG-W-----SRYMPE
GMQCSCGPDYYTHNPDYHNESYVLYMFVIHFIIPVVVIFFSYGRLICKVREAAAQ-----
------------------------------------------------------------
------------------------------------------------------------
-------------------------------QQESATTQK------AEKEVTRMVILMVL
GFMLAWTPYAVVAFWI---FTNKGADFTATLMAVPAFFSKSSSLYNPIIYVLMNKQFRNC
MITTICCGKNPFGDEDVSSTVSQSKTEVSSV-SSSQVSPA--------------------
------------------------------------------------------------
---------------
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
-------------------MNGTEG-----------------------------------
------------KNFYVP----MSNRTGLV--------RSPFEYPQ--------------
-----Y-YLAEPW---------QFKILALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLN
FILVNLAVAGTIMVCFGF-TVTFYTAIN-GYFV--LGPTGCAVEGFMATLGGEVALWSLV
VLAIERYIVVCKPMGSF-KFSSSHAFAGIAFTWVMALAC-AAPPLFG-W-----SRYIPE
GMQCSCGPDYYTLNPDYNNESYVIYMFVCHFILPVAVIFFTYGRLVCTVKAAAAQ-----
------------------------------------------------------------
------------------------------------------------------------
-------------------------------QQDSASTQK------AEREVTKMVILMVF
GFLIAWTPYATVAAWI---FFNKGADFSAKFMAIPAFFSKSSALYNPVIYVLLNKQFRNC
MLTTIFCGKNPLGDDE-SSTVSTSKTE------VSSVSPA--------------------
------------------------------------------------------------
---------------
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
-------------------MNGTEG-----------------------------------
------------NNFYVP----LSNRTGLV--------RSPFEYPQ--------------
-----Y-YLAEPW---------QFKLLAVYMFFLICLGLPINGLTLICTAQHKKLRQPLN
FILVNLAVAGAIMVCFGF-TVTFYTAIN-GYFA--LGPTGCAVEGFMATLGGEVALWSLV
VLAIERYIVVCKPMGSF-KFSSTHASAGIAFTWVMAMAC-AAPPLVG-W-----SRYIPE
GIQCSCGPDYYTLNPEYNNESYVLYMFICHFILPVTIIFFTYGRLVCTVKAAAAQ-----
------------------------------------------------------------
------------------------------------------------------------
-------------------------------QQDSASTQK------AEREVTKMVILMVL
GFLVAWTPYATVAAWI---FFNKGAAFSAQFMAIPAFFSKTSALYNPVIYVLLNKQFRSC
MLTTLFCGKNPLGDEE-SSTVSTSKTE------VSSVSPA--------------------
------------------------------------------------------------
---------------
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
-------------------MKQVPEF----------------------------------
-----------HEDFYIPIPLDINNLSAY----------SPFLVPQ--------------
-----D-HLGNQG---------IFMAMSVFMFFIFIGGASINILTILCTIQFKKLRSHLN
YILVNLSIANLFVAIFGS-PLSFYSFFN-RYFI--FGATACKIEGFLATLGGMVGLWSLA
VVAFERWLVICKPLGNF-TFKTPHAIAGCILPWISALAA-SLPPLFG-W-----SRYIPE
GLQCSCGPDWYTTNNKYNNESYVMFLFCFCFAVPFGTIVFCYGQLLITLKLAAKA-----
------------------------------------------------------------
------------------------------------------------------------
-------------------------------QADSASTQK------AEREVTKMVVVMVL
GFLVCWAPYASFSLWI---VSHRGEEFDLRMATIPSCLSKASTVYNPVIYVLMNKQFRSC
MMKMV-CGKNIEEDE--AST-SSQVTQ------VSSVAPEK-------------------
------------------------------------------------------------
---------------
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
-------------------MRKMSE-----------------------------------
------------EEFYL-----FKNISSV----------GPWDGPQ--------------
-----Y-HIAPVW---------AFYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLN
YILVNVSFGGFLLCIFSV-FPVFVASCN-GYFV--FGRHVCALEGFLGTVAGLVTGWSLA
FLAFERYIVICKPFGNF-RFSSKHALTVVLATWTIGIGV-SIPPFFG-W-----SRFIPE
GLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLICFSYTQLLRALKAVAAQ-----
------------------------------------------------------------
------------------------------------------------------------
-------------------------------QQESATTQK------AEREVSRMVVVMVG
SFCVCYVPYAAFAMYM---VNNRNHGLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQAC
IMKMV-CGKAM--TDE-SDTCSSQKTEVSTV-SSTQVGPN--------------------
------------------------------------------------------------
---------------
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------DLAETVIAS-TISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLA
IISWERWLVVCKPFGNV-RFDAKLAIVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPH
GLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQ-----
------------------------------------------------------------
------------------------------------------------------------
-------------------------------QKESESTQK------AEKEVTRMVVVMVL
AFC---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
MAQQWSLQRLAGRHPQDSYEDSTQS-----------------------------------
------------SIFTYT----NSNST-----------RGPFEGPN--------------
-----Y-HIAPRW---------VYHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLN
WILVNLAVADLAETVIAS-TISVVNQVY-GYFV--LGHPMCVLEGYTVSLCGITGLWSLA
IISWERWMVVCKPFGNV-RFDAKLAIVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPH
GLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQ-----
------------------------------------------------------------
------------------------------------------------------------
-------------------------------QKESESTQK------AEKEVTRMVVVMVL
AFCFCWGPYAFFACFA---AANPGYPFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNC
ILQLF--GKKV--DDG-SELSSASKTEVSSV---SSVSPA--------------------
------------------------------------------------------------
---------------
>    10== Z68193   1 human Red Opsin <>[]
MAQQWSLQRLAGRHPQDSYEDSTQS-----------------------------------
------------SIFTYT----NSNST-----------RGPFEGPN--------------
-----Y-HIAPRW---------VYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLN
WILVNLAVADLAETVIAS-TISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLA
IISWERWLVVCKPFGNV-RFDAKLAIVGIAFSWIWSAVW-TAPPIFG-W-----SRYWPH
GLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAIRAVAKQ-----
------------------------------------------------------------
------------------------------------------------------------
-------------------------------QKESESTQK------AEKEVTRMVVVMIF
AYCVCWGPYTFFACFA---AANPGYAFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNC
ILQLF--GKKV--DDG-SELSSASKTEVSSV---SSVSPA--------------------
------------------------------------------------------------
---------------
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
MTEAWNVAVFAARRSRDD-DDTTRG-----------------------------------
------------SVFTYT----NTNNT-----------RGPFEGPN--------------
-----Y-HIAPRW---------VYNLVSFFMIIVVIASCFTNGLVLVATAKFKKLRHPLN
WILVNLAFVDLVETLVAS-TISVFNQIF-GYFI--LGHPLCVIEGYVVSSCGITGLWSLA
IISWERWFVVCKPFGNI-KFDSKLAIIGIVFSWVWAWGW-SAPPIFG-W-----SRYWPH
GLKTSCGPDVFSGSVELGCQSFMLTLMITCCFLPLFIIIVCYLQVWMAIRAVAAQ-----
------------------------------------------------------------
------------------------------------------------------------
-------------------------------QKESESTQK------AEREVSRMVVVMIV
AFCICWGPYASFVSFA---AANPGYAFHPLAAALPAYFAKSATIYNPVIYVFMNRQFRNC
IMQLF--GKKV--DDG-SEASTTSRTEVSSV-SNSSVAPA--------------------
------------------------------------------------------------
---------------
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
MA-AWEAAFAARRRHEE--EDTTRD-----------------------------------
------------SVFTYT----NSNNT-----------RGPFEGPN--------------
-----Y-HIAPRW---------VYNLTSVWMIFVVAASVFTNGLVLVATWKFKKLRHPLN
WILVNLAVADLGETVIAS-TISVINQIS-GYFI--LGHPMCVVEGYTVSACGITALWSLA
IISWERWFVVCKPFGNI-KFDGKLAVAGILFSWLWSCAW-TAPPIFG-W-----SRYWPH
GLKTSCGPDVFSGSSDPGVQSYMVVLMVTCCFFPLAIIILCYLQVWLAIRAVAAQ-----
------------------------------------------------------------
------------------------------------------------------------
-------------------------------QKESESTQK------AEKEVSRMVVVMIV
AYCFCWGPYTFFACFA---AANPGYAFHPLAAALPAYFAKSATIYNPIIYVFMNRQFRNC
ILQLF--GKKV--DDG-SEVST-SRTEVSSV-SNSSVSPA--------------------
------------------------------------------------------------
---------------
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
---------MSSNSSQAP-PNGTPG-----------------------------------
----------------------------------------PFDGPQ--------------
-----WPYQAPQS---------TYVGVAVLMGTVVACASVVNGLVIVVSICYKKLRSPLN
YILVNLAVADLLVTLCGS-SVSLSNNIN-GFFV--FGRRMCELEGFMVSLTGIVGLWSLA
ILALERYVVVCKPLGDF-QFQRRHAVSGCAFTWGWALLW-SAPPLLG-W-----SSYVPE
GLRTSCGPNWYTGGS--NNNSYILSLFVTCFVLPLSLILFSYTNLLLTLRAAAAQ-----
------------------------------------------------------------
------------------------------------------------------------
-------------------------------QKEADTTQR------AEREVTRMVIVMVM
AFLLCWLPYSTFALVV---ATHKGIIIQPVLASLPSYFSKTATVYNPIIYVFMNKQFQSC
LLEMLCCGYQPQRTGKASPGTPGPHADVTAAGLRNKVMPAHPV-----------------
------------------------------------------------------------
---------------
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
---------MESGNVSSSLFGNVST--ALRPEA---------------------------
------------------------RLSA---ETRLLGWNVPPEELR--------------
-------HIPEHWLTYPEPPESMNYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSN
ILVINLAFCDFMMMVKT--PIFIYNSFHQG-YA--LGHLGCQIFGIIGSYTGIAAGATNA
FIAYDRFNVITRPMEG--KMTHGKAIAMIIFIYMYATPW-VVACYTETW-----GRFVPE
GYLTSCTFDYLT--DNFDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKA-----
------------------------------------------------------------
---LRDQAKKMN----------VESL----------------------------------
-------------------------------RSNVDKNKE-----TAEIRIAKAAITICF
LFFCSWTPYGVMSLIG---AFGDKTLLTPGATMIPACACKMVACIDPFVYAISHPRYRME
LQKRCPWLAL--NEKA-PESSAVASTSTTQE-P-QQTTAA--------------------
------------------------------------------------------------
---------------
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
---------MEYHNVSSVL-GNVSS--VLRPDA---------------------------
------------------------RLSA---ESRLLGWNVPPDELR--------------
-------HIPEHWLIYPEPPESMNYLLGTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSN
ILVINLAFCDFMMMIKT--PIFIYNSFHQG-YA--LGHLGCQIFGVIGSYTGIAAGATNA
FIAYDRYNVITRPMEG--KMTHGKAIAMIIFIYLYATPW-VVACYTESW-----GRFVPE
GYLTSCTFDYLT--DNFDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKA-----
------------------------------------------------------------
---LRDQAKKMN----------VDSL----------------------------------
-------------------------------RSNVDKSKE-----AAEIRIAKAAITICF
LFFASWTPYGVMSLIG---AFGDKTLLTPGATMIPACTCKMVACIDPFVYAISHPRYRME
LQKRCPWLAI--SEKA-PESRAAISTSTTQE-Q-QQTTAA--------------------
------------------------------------------------------------
---------------
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
---------ME------PL-CNASEP-PLRPEA---------------------------
------------------------R-SSGNGDLQFLGWNVPPDQIQ--------------
-------YIPEHWLTQLEPPASMHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSN
MFVLNLAVFDLIMCLKA--PIF--NSFHRG-FAIYLGNTWCQIFASIGSYSGIGAGMTNA
AIGYDRYNVITKPMNR--NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPE
GYLTSCSFDYLS--DNFDTRLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKA-----
------------------------------------------------------------
---LREQAKKMN----------VESL----------------------------------
-------------------------------RSNVDKSKE-----TAEIRIAKAAITICF
LFFVSWTPYGVMSLIG---AFGDKSLLTQGATMIPACTCKLVACIDPFVYAISHPRYRLE
LQKRCPWLGV--NEKS-GEISSAQST-TTQE-Q-QQTTAA--------------------
------------------------------------------------------------
---------------
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
---------MD------AL-CNASEP-PLRPEA---------------------------
------------------------RMSSGSDELQFLGWNVPPDQIQ--------------
-------YIPEHWLTQLEPPASMHYMLGVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSN
MFVLNLAVFDLIMCLKA--PIFIYNSFHRG-FA--LGNTWCQIFASIGSYSGIGAGMTNA
AIGYDRYNVITKPMNR--NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPE
GYLTSCSFDYLS--DNFDTRLFVGTIFLFSFVVPTLMILYYYSQIVGHVFNHEKA-----
------------------------------------------------------------
---LREQAKKMN----------VESL----------------------------------
-------------------------------RSNVDKSKE-----TAEIRIAKAAITICF
LFFVSWTPYGVMSLIG---AFGDKSLLTPGATMIPACTCKLVACIEPFVYAISHPRYRME
LQKRCPWLGV--NEKS-GEASSAQST-TTQE-QTQQTSAA--------------------
------------------------------------------------------------
---------------
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
-------------------MTNATGP-QMAYYGAASM-----------------------
------------D-FGYP-----EGVSIVD--------FVRPEIKP--------------
-------YVHQHWYNYPPVNPMWHYLLGVIYLFLGTVSIFGNGLVIYLFNKSAALRTPAN
ILVVNLALSDLIMLTTNV-PFFTYNCFSGGVWM--FSPQYCEIYACLGAITGVCSIWLLC
MISFDRYNIICNGFNG-PKLTTGKAVVFALISWVIAIGC-ALPPFFG-W-----GNYILE
GILDSCSYDYLT--QDFNTFSYNIFIFVFDYFLPAAIIVFSYVFIVKAIFAHEAA-----
------------------------------------------------------------
---MRAQAKKMN----------VSTL----------------------------------
-------------------------------RS-NEADAQ-----RAEIRIAKTALVNVS
LWFICWTPYALISLKG---VMGDTSGITPLVSTLPALLAKSCSCYNPFVYAISHPKYRLA
ITQHLPWFCV--HETE-TKSNDDSQSNSTVA-QDKA------------------------
------------------------------------------------------------
---------------
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
-------------------MANVTGP-QMAFYGSGAA-----------------------
------------T-FGYP-----EGMTVAD--------FVPDRVKH--------------
-------MVLDHWYNYPPVNPMWHYLLGVVYLFLGVISIAGNGLVIYLYMKSQALKTPAN
MLIVNLALSDLIMLTTNF-PPFCYNCFSGGRWM--FSGTYCEIYAALGAITGVCSIWTLC
MISFDRYNIICNGFNG-PKLTQGKATFMCGLAWVISVGW-SLPPFFG-W-----GSYTLE
GILDSCSYDYFT--RDMNTITYNICIFIFDFFLPASVIVFSYVFIVKAIFAHEAA-----
------------------------------------------------------------
---MRAQAKKMN----------VTNL----------------------------------
-------------------------------RS-NEAETQ-----RAEIRIAKTALVNVS
LWFICWTPYAAITIQG---LLGNAEGITPLLTTLPALLAKSCSCYNPFVYAISHPKFRLA
ITQHLPWFCV--HEKD-PNDVEENQSSNTQT-QEKS------------------------
------------------------------------------------------------
---------------
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
---------ME----SFAVAAAQLGP-HFAPLS---------------------------
------------------------NGSVVD--------KVTPDMAH--------------
-------LISPYWNQFPAMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPAN
LLVINLAISDFGIMITNT-PMMGINLYFET-WV--LGPMMCDIYAGLGSAFGCSSIWSMC
MISLDRYQVIVKGMAG-RPMTIPLALGKM---------------------------YVPE
GNLTSCGIDYLE--RDWNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKA-----
------------------------------------------------------------
---MREQAKKMN----------VKSL----------------------------------
-------------------------------RS-SEDAEK-----SAEGKLAKVALVTIT
LWFMAWTPYLVINCMG---LFKF-EGLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLA
LKEKCPCCVFGKVDDG-KSSDAQSQA-TASE-AESKA-----------------------
------------------------------------------------------------
---------------
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
---------ME----SFAVAAAQLGP-HFAPLS---------------------------
------------------------NGSVVD--------KVTPDMAH--------------
-------LISPYWNQFPAMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPAN
LLVINLAISDFGIMITNT-PMMGINLYFET-WV--LGPMMCDIYAGLGSAFGCSSIWSMC
MISLDRYQVIVKGMAG-RPMTIPLALGKIAYIWFMSSIW-CLAPAFG-W-----SRYVPE
GNLTSCGIDYLE--RDWNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKA-----
------------------------------------------------------------
---MREQAKKMN----------VKSL----------------------------------
-------------------------------RS-SEDAEK-----SAEGKLAKVALVTIT
LWFMAWTPYLVINCMG---LFKF-EGLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLA
LKEKCPCCVFGKVDDG-KSSDAQSQA-TASE-AESKA-----------------------
------------------------------------------------------------
---------------
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
---------MD----SFAAVATQLGP-QFAAPS---------------------------
------------------------NGSVVD--------KVTPDMAH--------------
-------LISPYWDQFPAMDPIWAKILTAYMIIIGMISWCGNGVVIYIFATTKSLRTPAN
LLVINLAISDFGIMITNT-PMMGINLYFET-WV--LGPMMCDIYAGLGSAFGCSSIWSMC
MISLDRYQVIVKGMAG-RPMTIPLALGKIAYIWFMSTIWCCLAPVFG-W-----SRYVPE
GNLTSCGIDYLE--RDWNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKA-----
------------------------------------------------------------
---MREQAKKMN----------VKSL----------------------------------
-------------------------------RS-SEDADK-----SAEGKLAKVALVTIS
LWFMAWTPYLVINCMG---LFKF-EGLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLA
LKEKCPCCVFGKVDDG-KSSEAQSQA-TTSE-AESKA-----------------------
------------------------------------------------------------
---------------
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
M----ERSHLP----ETPFDLAHSGP-RFQAQSSG-------------------------
------------------------NGSVLD--------NVLPDMAH--------------
-------LVNPYWSRFAPMDPMMSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPAN
LLVLNLAFSDFCMMASQS-PVMIINFYYET-WV--LGPLWCDIYAGCGSLFGCVSIWSMC
MIAFDRYNVIVKGING-TPMTIKTSIMKILFIWMMAVFW-TVMPLIG-W-----SAYVPE
GNLTACSIDYMT--RMWNPRSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKA-----
------------------------------------------------------------
---MREQAKKMN----------VKSL----------------------------------
-------------------------------RS-SEDCDK-----SAEGKLAKVALTTIS
LWFMAWTPYLVICYFG---LFKI-DGLTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIV
LKEKCPMCVFGNTDEP-KPDAPASDTETTSE-ADSKA-----------------------
------------------------------------------------------------
---------------
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
M----ERSLLP----EPPLAMALLGP-RFEAQTGG-------------------------
------------------------NRSVLD--------NVLPDMAP--------------
-------LVNPHWSRFAPMDPTMSKILGLFTLVILIISCCGNGVVVYIFGGTKSLRTPAN
LLVLNLAFSDFCMMASQS-PVMIINFYYET-WV--LGPLWCDIYAACGSLFGCVSIWSMC
MIAFDRYNVIVKGING-TPMTIKTSIMKIAFIWMMAVFW-TIMPLIG-W-----SSYVPE
GNLTACSIDYMT--RQWNPRSYLITYSLFVYYTPLFMICYSYWFIIATVAAHEKA-----
------------------------------------------------------------
---MRDQAKKMN----------VKSL----------------------------------
-------------------------------RS-SEDCDK-----SAENKLAKVALTTIS
LWFMAWTPYLIICYFG---LFKI-DGLTPLTTIWGATFAKTSAVYNPIVYGISHPNDRLV
LKEKCPMCVCGTTDEP-KPDAPPSDTETTSE-AESKD-----------------------
------------------------------------------------------------
---------------
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
-------------------MIAVSGP-SYEAFSYGGQ-----------------------
------------ARF--------NNQTVVD--------KVPPDMLH--------------
-------LIDANWYQYPPLNPMWHGILGFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSN
LFVINLAISNFLMMFCMS-PPMVINCYYET-WV--LGPLFCQIYAMLGSLFGCGSIWTMT
MIAFDRYNVIVKGLSG-KPLSINGALIRIIAIWLFSLGW-TIAPMFG-W-----NRYVPE
GNMTACGTDYFN--RGLLSASYLVCYGIWVYFVPLFLIIYSYWFIIQAVAAHEKN-----
------------------------------------------------------------
---MREQAKKMN----------VASL----------------------------------
-------------------------------RS-SENQNT-----SAECKLAKVALMTIS
LWFMAWTPYLVINFSG---IFNL-VKISPLFTIWGSLFAKANAVYNPIVYGISHPKYRAA
LFAKFPSLAC-AAEPS-SDAVSTTSGTTTVT-DNEKSNA---------------------
------------------------------------------------------------
---------------
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
---------------------MANQL-SYSSLGWPYQ-----------------------
------------P-----------NASVVD--------TMPKEMLY--------------
-------MIHEHWYAFPPMNPLWYSILGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTN
LLVVNLAFSDFCMMAFMM-PTMTSNCFAET-WI--LGPFMCEVYGMAGSLFGCASIWSMV
MITLDRYNVIVRGMAA-APLTHKKATLLLLFVWIWSGGW-TILPFFG-W-----SRYVPE
GNLTSCTVDYLT--KDWSSASYVVIYGLAVYFLPLITMIYCYFFIVHAVAEHEKQ-----
------------------------------------------------------------
---LREQAKKMN----------VASL----------------------------------
-------------------------------RANADQQKQ-----SAECRLAKVAMMTVG
LWFMAWTPYLIISWAG---VFSSGTRLTPLATIWGSVFAKANSCYNPIVYGISHPRYKAA
LYQRFPSLACGSGESG-SDVKSEASATTTME-EKPKIPEA--------------------
------------------------------------------------------------
---------------
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
---------------------MVEST-TLVNQTWWY------------------------
------------------------NPTVD-------------------------------
--------IHPHWAKFDPIPDAVYYSVGIFIGVVGIIGILGNGVVIYLFSKTKSLQTPAN
MFIINLAMSDLSFSAINGFPLKTISAFMKK-WI--FGKVACQLYGLLGGIFGFMSINTMA
MISIDRYNVIGRPMAASKKMSHRRAFLMIIFVWMWSIVW-SVGPVFN-W-----GAYVPE
GILTSCSFDYLS--TDPSTRSFILCMYFCGFMLPIIIIAFCYFNIVMSVSNHEKE-----
------------------------------------------------------------
---MAAMAKRLN----------AKEL----------------------------------
-------------------------------R--KAQAGA-----SAEMKLAKISMVIIT
QFMLSWSPYAIIALLA---QFGPAEWVTPYAAELPVLFAKASAIHNPIVYSVSHPKFREA
IQTTFPWLLTCCQFDE-KECEDANDAEEEVV-ASER--GGESRDAAQMKEMMAMMQKMQA
QQAAYQPPPPPQGY--PPQGYPPQGAYPPPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAP
QGAPPQGVDNQAYQA
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
----------------------MGRD-LRDNETWWY------------------------
------------------------NPSIV-------------------------------
--------VHPHWREFDQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPAN
MFIINLAFSDFTFSLVNGFPLMTISCFLKK-WI--FGFAACKVYGFIGGIFGFMSIMTMA
MISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLW-AIGPIFG-W-----GAYTLE
GVLCNCSFDYIS--RDSTTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKE-----
------------------------------------------------------------
---MAAMAKRLN----------AKEL----------------------------------
-------------------------------R--KAQAGA-----NAEMRLAKISIVIVS
QFLLSWSPYAVVALLA---QFGPLEWVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREA
ISQTFPWVLTCCQFDD-KETEDDKDAETEIP-AGESSDAAPSADAAQMKEMMAMMQKMQQ
QQAAY----PPQGYAPPPQGYPPQGY--PPQGYPPQGYPPQGYPP---PPQGAPPQ-GAP
PAAPPQGVDNQAYQA
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
---------------------------MMDVNSSGRPDLYGHLRSFL-LPEVGRGLPDLS
PDGGADPVAGSWAPHLLS------EVTASP--------APTWDAPPDNASGCGEQIN---
-----YGRVE-------------KVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSN
YLIVSLALADLSVAVAVM-PFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLC
VISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVND
DKVCLISQDF----------GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKF--
-----------------------------------------------------PGFPRV-
---EPDSVIALNG---------IVKL----------------------QK---------E
VEECAN------------------LSRLLKHERKNISIFK------REQKAATTLGIIVG
AFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTT
YRSLL-QCQYRNINRKLSAAGMHEALKLAE-------RPERPEFVLQNADYCR-------
------------------------------------------------------------
----KKGHDS-----
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
------------------------------------------------------------
------------MPHLLS---GFLEVTASP--------APTWDAPPDNVSGCGEQIN---
-----YGRVE-------------KVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSN
YLIVSLALADLSVAVAVM-PFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLC
VISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVND
DKVCLISQDF----------GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKF--
-----------------------------------------------------PGFPRV-
---QPESVISLNG---------VVKL----------------------QK---------E
VEECAN------------------LSRLLKHERKNISIFK------REQKAATTLGIIVG
AFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRPT
SRSLL-QCQYRNINRKLSAAGMHEALKLAE-------RPERSEFVLQNSDHCG-------
------------------------------------------------------------
----KKGHDT-----
>    31=p A47425 serotonin receptor 5HT-7 - rat
------------------------------------------------------------
------------MPHLLS---GFLEVTASP--------APTWDAPPDNVSGCGEQIN---
-----YGRVE-------------KVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSN
YLIVSLALADLSVAVAVM-PFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLC
VISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVND
DKVCLISQDF----------GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKF--
-----------------------------------------------------PGFPRV-
---QPESVISLNG---------VVKL----------------------QK---------E
VEECAN------------------LSRLLKHERKNISIFK------REQKAATTLGIIVG
AFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTT
YRSLL-QCQYRNINRKLSAAGMHEALKLAE-------RPERSEFVLQNSDHCG-------
------------------------------------------------------------
----KKGHDT-----
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
----------------------------MDVLSP--------------------------
---------------------GQGNNTTSP--------PAPFET-GGNTTGISDVT----
-----VSYQ---------------VITSLLLGTLIFCAVLGNACVVAAIALERSLQNVAN
YLIGSLAVTDLMVSVLVL-PMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLC
AIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLI-SIPPMLG-WRTPEDRSDPD-
--ACTISKDH----------GYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK-----
----------------------------------TVKKVEKTGADTRHGASPAPQPKKS-
----------VNGESGSR---------NWRLGVESKAGGALCANGAVRQGDDGAALEVIE
VHRVGNSKEHLPLPSEAG--PTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMG
TFILCWLPFFIVALVLPF-CESSC-HMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNA
FKKII-KCKFCRQ-----------------------------------------------
------------------------------------------------------------
---------------
>    33=p A35181 serotonin receptor class 1A - rat
----------------------------MDVFSF--------------------------
---------------------GQGNNTTAS--------QEPFGT-GGNVTSISDVT----
-----FSYQ---------------VITSLLLGTLIFCAVLGNACVVAAIALERSLQNVAN
YLIGSLAVTDLMVSVLVL-PMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLC
AIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLI-SIPPMLG-WRTPEDRSDPD-
--ACTISKDH----------GYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK-----
----------------------------------TVRKVEKKGAGTSLGTSSAPPPKKS-
----------LNGQPGSG---------DWRRCAENRAVGTPCTNGAVRQGDDEATLEVIE
VHRVGNSKEHLPLPSESG--SNSYAPACLERKNERNAEAKRKMALARERKTVKTLGIIMG
TFILCWLPFFIVALVLPF-CESSC-HMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNA
FKKII-KCKFCRR-----------------------------------------------
------------------------------------------------------------
---------------
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
M------------------ANFTFGDLALDVARMG-----GLASTPSGLRSTGLTTPGLS
PTGLVTSDFN--DSYGLT---GQFINGSHS--------SRSRDNASANDTSATNMTDDRY
WSLTVYSHEH-------------LVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVAN
YLILSLAVADLMVAVLVM-PLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLV
AIAMDRYWAVTS-IDYIRRRSARRILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDK
TGTCIISQDK----------GYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQM
TKARLKTEETTLVASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNR
AKKLPENANGVNSNSSS----------SERLKQIQIETAEAFANGCA----EEASIAMLE
RQ-CNNGKKISSNDTPYS-------------RTREKLELK------RERKAARTLAIITG
AFLICWLPFFIIALIGPF-VDPE--GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSA
FQKIL-FGKYRRGHR---------------------------------------------
------------------------------------------------------------
---------------
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
M------------------ANFTFGDLALDVARMG-----GLASTPSGLRSTGLTTPGLS
PTGLVTSDFN--DSYGLT---GQFINGSHS--------SRSRDNASANDTSATNMTDDRY
WSLTVYSHEH-------------LVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVAN
YLILSLAVADLMVAVLVM-PLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLV
AIAMDRYWAVTS-IDYIRRRSARRILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDK
TGTCIISQDK----------GYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQM
TKARLKTEETTLVASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNR
AKKLPENANGVNSNSSS----------SERLKQIQIETAEAFANGCA----EEASIAMLE
RQ-CNNGKKISSNDTPYS-------------RTREKLELK------RERKAARTLAIITG
AFLICWLPFFIIALIGPF-VDPE--GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSA
FQKIL-FGKYRRGHR---------------------------------------------
------------------------------------------------------------
---------------
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
-------------------MEGAEGQEELDWEAL-------YLRLP--LQNCSWNSTGWE
PNWNVTVVPN--TTWW------------QA--------SAPFDTPAALVRAAAK------
---------------------------AVVLGLLILATVVGNVFVIAAILLERHLRSAAN
NLILSLAVADLLVACLVM-PLGAVYEVV-QRWT--LGPELCDMWTSGDVLCCTASILHLV
AIALDRYWAVTN-IDYIHASTAKRVGMMIACVWTVSFFV-CIAQLLG-WKDPDWNQRVSE
DLRCVVSQDV----------GYQIFATASSFYVPVLIILILYWRIYQTARKRIR------
---------------------------------------RRRGATARGGVGPPP------
---VPAGGALVAGGGSGGIAAAVVAVIGRPLPTISETTTTGFTNVSS----NNTSP---E
KQSCANGLEADPPTTGYGAVAAAYYPSLVRRKPKEAADSK------RERKAAKTLAIITG
AFVACWLPFFVLAILVPT-CDCE---VSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHA
FQRLL-CGRRVRRRRA----------------------PQ--------------------
------------------------------------------------------------
---------------
