>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
M------------------NGTE-G------DNFYVPF----SNKTGLARSPYEYPQY--
--------------------------------------------------YLAEPW----
---------------KYSALAAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLA
MANLFMVLFG-FTVTMYTSMN-GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERY
IVICKPMGNF-RFGNTHAIMGVAFTWIMALAC-AAPPLVG-WS-----RYIPEGMQCSCG
PDYYTLNPNFNNESYVVYMFVVHFLVPFVIIFFCYGRLLCTVKEAAAAQQESA-------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------STQKAEKEVTRMVVLMVIGFLVCWVPYAS
VAFYIFT---HQGS-DFGATFMTLPAFFAKSSALYNPVIYILMNKQFRNCMITTL-----
CC-----GKNPLGDDE-SGA-STSK-TEVSSVS-TSPVSPA-------------------
------------------------------------------------------------
---------------
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
M------------------NGTE-G------PNFYVPF----SNITGVVRSPFEQPQY--
--------------------------------------------------YLAEPW----
---------------QFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLA
VADLFMVFGG-FTTTLYTSLH-GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERY
VVVCKPMSNF-RFGENHAIMGVAFTWVMALAC-AAPPLVG-WS-----RYIPEGMQCSCG
IDYYTLKPEVNNESFVIYMFVVHFTIPMIVIFFCYGQLVFTVKEAAAQQQESA-------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------TTQKAEKEVTRMVIIMVIFFLICWLPYAS
VAMYIFT---HQGS-NFGPIFMTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSL-----
CC-----GKNPLGDDE-ASA-TASK-TETSQVA-PA------------------------
------------------------------------------------------------
---------------
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
M------------------NGTE-G------INFYVPM----SNKTGVVRSPFEYPQY--
--------------------------------------------------YLAEPW----
---------------KYRLVCCYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLA
VADLFMACFG-FTVTFYTAWN-GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERY
IVVCKPMGNF-RFSATHAMMGIAFTWVMAFSC-AAPPLFG-WS-----RYMPEGMQCSCG
PDYYTHNPDYHNESYVLYMFVIHFIIPVVVIFFSYGRLICKVREAAAQQQESA-------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------TTQKAEKEVTRMVILMVLGFMLAWTPYAV
VAFWIFT---NKGA-DFTATLMAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTI-----
CC-----GKNPFGDEDVSSTVSQSK-TEVSSVS-SSQVSPA-------------------
------------------------------------------------------------
---------------
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
M------------------NGTE-G------KNFYVPM----SNRTGLVRSPFEYPQY--
--------------------------------------------------YLAEPW----
---------------QFKILALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLA
VAGTIMVCFG-FTVTFYTAIN-GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERY
IVVCKPMGSF-KFSSSHAFAGIAFTWVMALAC-AAPPLFG-WS-----RYIPEGMQCSCG
PDYYTLNPDYNNESYVIYMFVCHFILPVAVIFFTYGRLVCTVKAAAAQQQDSA-------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------STQKAEREVTKMVILMVFGFLIAWTPYAT
VAAWIFF---NKGA-DFSAKFMAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTI-----
FC-----GKNPLGDDE-SSTVSTSK-TEVSSVS-PA------------------------
------------------------------------------------------------
---------------
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
M------------------NGTE-G------NNFYVPL----SNRTGLVRSPFEYPQY--
--------------------------------------------------YLAEPW----
---------------QFKLLAVYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLA
VAGAIMVCFG-FTVTFYTAIN-GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERY
IVVCKPMGSF-KFSSTHASAGIAFTWVMAMAC-AAPPLVG-WS-----RYIPEGIQCSCG
PDYYTLNPEYNNESYVLYMFICHFILPVTIIFFTYGRLVCTVKAAAAQQQDSA-------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------STQKAEREVTKMVILMVLGFLVAWTPYAT
VAAWIFF---NKGA-AFSAQFMAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTL-----
FC-----GKNPLGDEE-SSTVSTSK-TEVSSVS-PA------------------------
------------------------------------------------------------
---------------
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
M------------------KQVP-EFH----EDFYIPIPL--DINNLSAYSPFLVPQD--
--------------------------------------------------HLGNQG----
---------------IFMAMSVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLS
IANLFVAIFG-SPLSFYSFFN-RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAFERW
LVICKPLGNF-TFKTPHAIAGCILPWISALAA-SLPPLFG-WS-----RYIPEGLQCSCG
PDWYTTNNKYNNESYVMFLFCFCFAVPFGTIVFCYGQLLITLKLAAKAQADSA-------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------STQKAEREVTKMVVVMVLGFLVCWAPYAS
FSLWIVS---HRGE-EFDLRMATIPSCLSKASTVYNPVIYVLMNKQFRSCMMKMV-----
C------GKN-IEEDE-AST-SSQV-TQVSSVA-PEK-----------------------
------------------------------------------------------------
---------------
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
M------------------RKMS-E------EEFYL-------FKNISSVGPWDGPQY--
--------------------------------------------------HIAPVW----
---------------AFYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVS
FGGFLLCIFS-VFPVFVASCN-GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERY
IVICKPFGNF-RFSSKHALTVVLATWTIGIGV-SIPPFFG-WS-----RFIPEGLQCSCG
PDWYTVGTKYRSESYTWFLFIFCFIVPLSLICFSYTQLLRALKAVAAQQQESA-------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------TTQKAEREVSRMVVVMVGSFCVCYVPYAA
FAMYMVN---NRNH-GLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIMKMV-----
C------GKA-MTDES-DTC-SSQK-TEVSTVS-STQVGPN-------------------
------------------------------------------------------------
---------------
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--DLAETVIA-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERW
LVVCKPFGNV-RFDAKLAIVGIAFSWIWAAVW-TAPPIFG-WS-----RYWPHGLKTSCG
PDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQQKESE-------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------STQKAEKEVTRMVVVMVLAFC--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
MAQQWSLQRLAGRHPQDSYEDSTQS------SIFTY-------TNSNSTRGPFEGPNY--
--------------------------------------------------HIAPRW----
---------------VYHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLA
VADLAETVIA-STISVVNQVY-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERW
MVVCKPFGNV-RFDAKLAIVGIAFSWIWAAVW-TAPPIFG-WS-----RYWPHGLKTSCG
PDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQQKESE-------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------STQKAEKEVTRMVVVMVLAFCFCWGPYAF
FACFAAA---NPGY-PFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLF-----
-------GKK-VDDGS-ELS-SASK-TEVSSVS---SVSPA-------------------
------------------------------------------------------------
---------------
>    10== Z68193   1 human Red Opsin <>[]
MAQQWSLQRLAGRHPQDSYEDSTQS------SIFTY-------TNSNSTRGPFEGPNY--
--------------------------------------------------HIAPRW----
---------------VYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLA
VADLAETVIA-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERW
LVVCKPFGNV-RFDAKLAIVGIAFSWIWSAVW-TAPPIFG-WS-----RYWPHGLKTSCG
PDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAIRAVAKQQKESE-------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------STQKAEKEVTRMVVVMIFAYCVCWGPYTF
FACFAAA---NPGY-AFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLF-----
-------GKK-VDDGS-ELS-SASK-TEVSSVS---SVSPA-------------------
------------------------------------------------------------
---------------
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
MTEAWNVAVFAARRSRDD-DDTTRG------SVFTY-------TNTNNTRGPFEGPNY--
--------------------------------------------------HIAPRW----
---------------VYNLVSFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLA
FVDLVETLVA-STISVFNQIF-GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERW
FVVCKPFGNI-KFDSKLAIIGIVFSWVWAWGW-SAPPIFG-WS-----RYWPHGLKTSCG
PDVFSGSVELGCQSFMLTLMITCCFLPLFIIIVCYLQVWMAIRAVAAQQKESE-------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------STQKAEREVSRMVVVMIVAFCICWGPYAS
FVSFAAA---NPGY-AFHPLAAALPAYFAKSATIYNPVIYVFMNRQFRNCIMQLF-----
-------GKK-VDDGS-EAS-TTSR-TEVSSVS-NSSVAPA-------------------
------------------------------------------------------------
---------------
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
MA-AWE-AAFAARRRHEE-EDTTRD------SVFTY-------TNSNNTRGPFEGPNY--
--------------------------------------------------HIAPRW----
---------------VYNLTSVWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLA
VADLGETVIA-STISVINQIS-GYFI--LGHPMCVVEGYTVSACGITALWSLAIISWERW
FVVCKPFGNI-KFDGKLAVAGILFSWLWSCAW-TAPPIFG-WS-----RYWPHGLKTSCG
PDVFSGSSDPGVQSYMVVLMVTCCFFPLAIIILCYLQVWLAIRAVAAQQKESE-------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------STQKAEKEVSRMVVVMIVAYCFCWGPYTF
FACFAAA---NPGY-AFHPLAAALPAYFAKSATIYNPIIYVFMNRQFRNCILQLF-----
-------GKK-VDDGS-EVS-T-SR-TEVSSVS-NSSVSPA-------------------
------------------------------------------------------------
---------------
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
-----------------------MS------SNSSQ-------APPNGTPGPFDGPQW--
-------------------------------------------------PYQAPQS----
---------------TYVGVAVLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLA
VADLLVTLCG-SSVSLSNNIN-GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILALERY
VVVCKPLGDF-QFQRRHAVSGCAFTWGWALLW-SAPPLLG-WS-----SYVPEGLRTSCG
PNWYTGGSN--NNSYILSLFVTCFVLPLSLILFSYTNLLLTLRAAAAQQKEAD-------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------TTQRAEREVTRMVIVMVMAFLLCWLPYST
FALVVAT---HKGI-IIQPVLASLPSYFSKTATVYNPIIYVFMNKQFQSCLLEML-----
CCGYQ--PQR-TGKAS-PGT-PGPH-ADVTAAGLRNKVMPAHPV----------------
------------------------------------------------------------
---------------
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
M------------------ESGNVS------SSLF------------GNVSTALRPEA--
-------------------------RLSA---E---TRLLGWNVPPEELRHIPEHWLTYP
----------EPPESMNYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLA
FCDFMMMVK--TPIFIYNSFH-QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRF
NVITRPMEG--KMTHGKAIAMIIFIYMYATPW-VVACYTETWG-----RFVPEGYLTSCT
FDYLTDN--FDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKKMNVES
------------------------------------------------------------
------------------------------------------------------------
-----------------LRS-------NVDKNKETAEIRIAKAAITICFLFFCSWTPYGV
MSLIGAF---GDKT-LLTPGATMIPACACKMVACIDPFVYAISHPRYRMELQKRCPWL--
AL-----NEK-APESS-AVA-STST-TQEPQQT---------------------------
TAA---------------------------------------------------------
---------------
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
M------------------EYHNVS------SVL-------------GNVSSVLRPDA--
-------------------------RLSA---E---SRLLGWNVPPDELRHIPEHWLIYP
----------EPPESMNYLLGTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLA
FCDFMMMIK--TPIFIYNSFH-QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRY
NVITRPMEG--KMTHGKAIAMIIFIYLYATPW-VVACYTESWG-----RFVPEGYLTSCT
FDYLTDN--FDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKKMNVDS
------------------------------------------------------------
------------------------------------------------------------
-----------------LRS-------NVDKSKEAAEIRIAKAAITICFLFFASWTPYGV
MSLIGAF---GDKT-LLTPGATMIPACTCKMVACIDPFVYAISHPRYRMELQKRCPWL--
AI-----SEK-APESR-AAI-STST-TQEQQQT---------------------------
TAA---------------------------------------------------------
---------------
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
M------------------EPLC------------------------NASEPPLRPEA--
-------------------------R-SSGNGD---LQFLGWNVPPDQIQYIPEHWLTQL
----------EPPASMHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLA
VFDLIMCLK--APIF--NSFH-RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRY
NVITKPMNR--NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFWD-----RFVPEGYLTSCS
FDYLSDN--FDTRLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKKMNVES
------------------------------------------------------------
------------------------------------------------------------
-----------------LRS-------NVDKSKETAEIRIAKAAITICFLFFVSWTPYGV
MSLIGAF---GDKS-LLTQGATMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWL--
GV-----NEK-SGEIS-SAQ-STTT-QEQQQTT---------------------------
AA----------------------------------------------------------
---------------
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
M------------------DALC------------------------NASEPPLRPEA--
-------------------------RMSSGSDE---LQFLGWNVPPDQIQYIPEHWLTQL
----------EPPASMHYMLGVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLA
VFDLIMCLK--APIFIYNSFH-RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRY
NVITKPMNR--NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFWD-----RFVPEGYLTSCS
FDYLSDN--FDTRLFVGTIFLFSFVVPTLMILYYYSQIVGHVFNHEKALREQAKKMNVES
------------------------------------------------------------
------------------------------------------------------------
-----------------LRS-------NVDKSKETAEIRIAKAAITICFLFFVSWTPYGV
MSLIGAF---GDKS-LLTPGATMIPACTCKLVACIEPFVYAISHPRYRMELQKRCPWL--
GV-----NEK-SGEAS-SAQ-STTT-QEQTQQT---------------------------
SAA---------------------------------------------------------
---------------
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
M------------------TNAT-------------------------------GPQMAY
-------YG--------------AASMDFGYPE---GVSIVDFVRPEIKPYVHQHWYNYP
----------PVNPMWHYLLGVIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLA
LSDLIMLTTN-VPFFTYNCFSGGVWM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRY
NIICNGFNGP-KLTTGKAVVFALISWVIAIGC-ALPPFFG-WG-----NYILEGILDSCS
YDYLTQD--FNTFSYNIFIFVFDYFLPAAIIVFSYVFIVKAIFAHEAAMRAQAKKMNVST
------------------------------------------------------------
------------------------------------------------------------
-----------------LRS--------NEADAQRAEIRIAKTALVNVSLWFICWTPYAL
ISLKGVM---GDTS-GITPLVSTLPALLAKSCSCYNPFVYAISHPKYRLAITQHLPWF--
CV-----HET-ETKSN-DDS-QSNS-TVAQDKA---------------------------
------------------------------------------------------------
---------------
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
M------------------ANVT-------------------------------GPQMAF
-------YG--------------SGAATFGYPE---GMTVADFVPDRVKHMVLDHWYNYP
----------PVNPMWHYLLGVVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLA
LSDLIMLTTN-FPPFCYNCFSGGRWM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRY
NIICNGFNGP-KLTQGKATFMCGLAWVISVGW-SLPPFFG-WG-----SYTLEGILDSCS
YDYFTRD--MNTITYNICIFIFDFFLPASVIVFSYVFIVKAIFAHEAAMRAQAKKMNVTN
------------------------------------------------------------
------------------------------------------------------------
-----------------LRS--------NEAETQRAEIRIAKTALVNVSLWFICWTPYAA
ITIQGLL---GNAE-GITPLLTTLPALLAKSCSCYNPFVYAISHPKFRLAITQHLPWF--
CV-----HEK-DPNDV-EEN-QSSN-TQTQEKS---------------------------
------------------------------------------------------------
---------------
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
M------------------ESFA-------------------------VAAAQLGPHF--
------------------------APLS--------NGSVVDKVTPDMAHLISPYWNQFP
----------AMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLA
ISDFGIMITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRY
QVIVKGMAGR-PMTIPLALGKM---------------------------YVPEGNLTSCG
IDYLERD--WNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKS
------------------------------------------------------------
------------------------------------------------------------
-----------------LRS--------SEDAEKSAEGKLAKVALVTITLWFMAWTPYLV
INCMGLF---KF-E-GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCC--
VF-----GKV-DDGKS-SDA-QSQA-TASEAES------KA-------------------
------------------------------------------------------------
---------------
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
M------------------ESFA-------------------------VAAAQLGPHF--
------------------------APLS--------NGSVVDKVTPDMAHLISPYWNQFP
----------AMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLA
ISDFGIMITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRY
QVIVKGMAGR-PMTIPLALGKIAYIWFMSSIW-CLAPAFG-WS-----RYVPEGNLTSCG
IDYLERD--WNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKS
------------------------------------------------------------
------------------------------------------------------------
-----------------LRS--------SEDAEKSAEGKLAKVALVTITLWFMAWTPYLV
INCMGLF---KF-E-GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCC--
VF-----GKV-DDGKS-SDA-QSQA-TASEAES------KA-------------------
------------------------------------------------------------
---------------
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
M------------------DSFA-------------------------AVATQLGPQF--
------------------------AAPS--------NGSVVDKVTPDMAHLISPYWDQFP
----------AMDPIWAKILTAYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLA
ISDFGIMITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRY
QVIVKGMAGR-PMTIPLALGKIAYIWFMSTIWCCLAPVFG-WS-----RYVPEGNLTSCG
IDYLERD--WNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKS
------------------------------------------------------------
------------------------------------------------------------
-----------------LRS--------SEDADKSAEGKLAKVALVTISLWFMAWTPYLV
INCMGLF---KF-E-GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCC--
VF-----GKV-DDGKS-SEA-QSQA-TTSEAES------KA-------------------
------------------------------------------------------------
---------------
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
M------------------ERSH--------------------LPETPFDLAHSGPRF--
------------------------QAQSSG------NGSVLDNVLPDMAHLVNPYWSRFA
----------PMDPMMSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLA
FSDFCMMASQ-SPVMIINFYY-ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRY
NVIVKGINGT-PMTIKTSIMKILFIWMMAVFW-TVMPLIG-WS-----AYVPEGNLTACS
IDYMTRM--WNPRSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKKMNVKS
------------------------------------------------------------
------------------------------------------------------------
-----------------LRS--------SEDCDKSAEGKLAKVALTTISLWFMAWTPYLV
ICYFGLF---KI-D-GLTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMC--
VF-----GNT-DEPKP-DAP-ASDTETTSEADS------KA-------------------
------------------------------------------------------------
---------------
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
M------------------ERSL--------------------LPEPPLAMALLGPRF--
------------------------EAQTGG------NRSVLDNVLPDMAPLVNPHWSRFA
----------PMDPTMSKILGLFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLA
FSDFCMMASQ-SPVMIINFYY-ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRY
NVIVKGINGT-PMTIKTSIMKIAFIWMMAVFW-TIMPLIG-WS-----SYVPEGNLTACS
IDYMTRQ--WNPRSYLITYSLFVYYTPLFMICYSYWFIIATVAAHEKAMRDQAKKMNVKS
------------------------------------------------------------
------------------------------------------------------------
-----------------LRS--------SEDCDKSAENKLAKVALTTISLWFMAWTPYLI
ICYFGLF---KI-D-GLTPLTTIWGATFAKTSAVYNPIVYGISHPNDRLVLKEKCPMC--
VC-----GTT-DEPKP-DAP-PSDTETTSEAES------KD-------------------
------------------------------------------------------------
---------------
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
M-------------------------------------------------IAVSGPSY--
------------------------EAFSYGGQARFNNQTVVDKVPPDMLHLIDANWYQYP
----------PLNPMWHGILGFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLA
ISNFLMMFCM-SPPMVINCYY-ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRY
NVIVKGLSGK-PLSINGALIRIIAIWLFSLGW-TIAPMFG-WN-----RYVPEGNMTACG
TDYFNRG--LLSASYLVCYGIWVYFVPLFLIIYSYWFIIQAVAAHEKNMREQAKKMNVAS
------------------------------------------------------------
------------------------------------------------------------
-----------------LRS--------SENQNTSAECKLAKVALMTISLWFMAWTPYLV
INFSGIF---NL-V-KISPLFTIWGSLFAKANAVYNPIVYGISHPKYRAALFAKFPSL--
AC-----AA--EPSSD-AVS-TTSG-TTTVTDN------EK------------------S
NA----------------------------------------------------------
---------------
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
M------------------ANQL---------------------------------SY--
------------------------SSLGWPYQP---NASVVDTMPKEMLYMIHEHWYAFP
----------PMNPLWYSILGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLA
FSDFCMMAFM-MPTMTSNCFA-ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRY
NVIVRGMAAA-PLTHKKATLLLLFVWIWSGGW-TILPFFG-WS-----RYVPEGNLTSCT
VDYLTKD--WSSASYVVIYGLAVYFLPLITMIYCYFFIVHAVAEHEKQLREQAKKMNVAS
------------------------------------------------------------
------------------------------------------------------------
-----------------LRA-------NADQQKQSAECRLAKVAMMTVGLWFMAWTPYLI
ISWAGVF---SSGT-RLTPLATIWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPSL--
AC-----GSG-ESGSD-VKS-EASA-TTTMEEK------PKIPEA---------------
------------------------------------------------------------
---------------
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
M------------------VEST----------------------TLVNQTWWYNPTV--
--------------------------------------------------DIHPHWAKFD
----------PIPDAVYYSVGIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLA
MSDLSFSAINGFPLKTISAFM-KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRY
NVIGRPMAASKKMSHRRAFLMIIFVWMWSIVW-SVGPVFN-WG-----AYVPEGILTSCS
FDYLSTD--PSTRSFILCMYFCGFMLPIIIIAFCYFNIVMSVSNHEKEMAAMAKRLNAKE
------------------------------------------------------------
------------------------------------------------------------
-----------------LRK---------AQAGASAEMKLAKISMVIITQFMLSWSPYAI
IALLAQF---GPAE-WVTPYAAELPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLT
CCQFD------EKECE-DAN-DAEE-EVVASER----GGESRDAAQMKEMMAMMQKMQAQ
QAAYQP---PPPPQGYPPQGYPPQGAYPPPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAP
QGAPPQGVDNQAYQA
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
M------------------GRDL-----------------------RDNETWWYNPSI--
--------------------------------------------------VVHPHWREFD
----------QVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLA
FSDFTFSLVNGFPLMTISCFL-KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRY
NVIGRPMAASKKMSHRRAFIMIIFVWLWSVLW-AIGPIFG-WG-----AYTLEGVLCNCS
FDYISRD--STTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKRLNAKE
------------------------------------------------------------
------------------------------------------------------------
-----------------LRK---------AQAGANAEMRLAKISIVIVSQFLLSWSPYAV
VALLAQF---GPLE-WVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLT
CCQFD------DKETE-DDK-DAET-EIPAGES--SDAAPSADAAQMKEMMAMMQKMQQQ
QAAYPPQGYAPPPQGYPPQGYPPQGY--PPQGYPPQGYPP---PPQGAPPQGAPP-----
-AAPPQGVDNQAYQA
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
MM-----------------DVNSSGR-----PDLYGHLRS-FLLPEVGRGLPDLSPDG--
----------GADPVAGSWAP---HLLS------------------EVTASPAPTWDAPP
DNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLA
LADLSVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRY
LGITRPLTYPVRQNGKCMAKMILSVWLLSASI-TLPPLFG-WA-----QNVNDDKVCLIS
QDF----------GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPG-------
-------FPRVEPDSVIALNG---------------------------------------
-----------------------IVKLQKE-------------------VEECAN-----
-------------LSRLLKHE------RKNISIFKREQKAATTLGIIVGAFTVCWLPFFL
LSTARPFICGTSCS-CIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLL-----
QCQYRNINRK-------LSAAGMHE-ALKLAER------PERPEFVL------------Q
NADY--------------------------------------------------------
-------CRKKGHDS
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
M-----------------------------------------------------------
--------------------P---HLLS--------GFL-------EVTASPAPTWDAPP
DNVSGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLA
LADLSVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRY
LGITRPLTYPVRQNGKCMAKMILSVWLLSASI-TLPPLFG-WA-----QNVNDDKVCLIS
QDF----------GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPG-------
-------FPRVQPESVISLNG---------------------------------------
-----------------------VVKLQKE-------------------VEECAN-----
-------------LSRLLKHE------RKNISIFKREQKAATTLGIIVGAFTVCWLPFFL
LSTARPFICGTSCS-CIPLWVERTCLWLGYANSLINPFIYAFFNRDLRPTSRSLL-----
QCQYRNINRK-------LSAAGMHE-ALKLAER------PERSEFVL------------Q
NSDH--------------------------------------------------------
-------CGKKGHDT
>    31=p A47425 serotonin receptor 5HT-7 - rat
M-----------------------------------------------------------
--------------------P---HLLS--------GFL-------EVTASPAPTWDAPP
DNVSGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLA
LADLSVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRY
LGITRPLTYPVRQNGKCMAKMILSVWLLSASI-TLPPLFG-WA-----QNVNDDKVCLIS
QDF----------GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPG-------
-------FPRVQPESVISLNG---------------------------------------
-----------------------VVKLQKE-------------------VEECAN-----
-------------LSRLLKHE------RKNISIFKREQKAATTLGIIVGAFTVCWLPFFL
LSTARPFICGTSCS-CIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLL-----
QCQYRNINRK-------LSAAGMHE-ALKLAER------PERSEFVL------------Q
NSDH--------------------------------------------------------
-------CGKKGHDT
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
M------------------DVLSPG-------------------------------QG--
------------------------NNTTSPPAPF-E---------------TGGNTTGIS
----------DVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLA
VTDLMVSVLV-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRY
WAITDPIDYVNKRTPRRAAALISLTWLIGFLI-SIPPMLG-WRTP---EDRSDPDACTIS
KDH----------GYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKK-----SVNGE--SGSRNWRLGVESKAGGALC-----------------
-------------------------------ANGAVRQGDDGAALEVIEVHRVGNSKEHL
PLPSEAG--PTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFI
VALVLPF---CESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKII-----
KCKFCRQ-----------------------------------------------------
------------------------------------------------------------
---------------
>    33=p A35181 serotonin receptor class 1A - rat
M------------------DVFSFG-------------------------------QG--
------------------------NNTTASQEPF-G---------------TGGNVTSIS
----------DVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLA
VTDLMVSVLV-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRY
WAITDPIDYVNKRTPRRAAALISLTWLIGFLI-SIPPMLG-WRTP---EDRSDPDACTIS
KDH----------GYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVRKVEKKGAGT
SLGTSSAPPPKK-----SLNGQ--PGSGDWRRCAENRAVGTPC-----------------
-------------------------------TNGAVRQGDDEATLEVIEVHRVGNSKEHL
PLPSESG--SNSYAPACLERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFI
VALVLPF---CESSCHMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKII-----
KCKFCRR-----------------------------------------------------
------------------------------------------------------------
---------------
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
M------------------ANFTFGDLALDVARMGGLASTPSGLRSTGLTTPGLSPTGLV
TSDFNDSYGLTGQFINGSHSSRSRDNASANDT--------------SATNMTDDRYWSLT
----------VYSHEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLA
VADLMVAVLV-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRY
WAVTS-IDYIRRRSARRILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIIS
QDK----------GYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKT
EETTLVASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPEN
ANGVNSNSSS----------SERLKQIQIETAEAFANGCAEEASIAML-ERQCNNGKK--
-----------------ISSNDTPYSRTREKLELKRERKAARTLAIITGAFLICWLPFFI
IALIGPF---VDPE-GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKIL-----
FGKYRRGHR---------------------------------------------------
------------------------------------------------------------
---------------
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
M------------------ANFTFGDLALDVARMGGLASTPSGLRSTGLTTPGLSPTGLV
TSDFNDSYGLTGQFINGSHSSRSRDNASANDT--------------SATNMTDDRYWSLT
----------VYSHEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLA
VADLMVAVLV-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRY
WAVTS-IDYIRRRSARRILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIIS
QDK----------GYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKT
EETTLVASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPEN
ANGVNSNSSS----------SERLKQIQIETAEAFANGCAEEASIAML-ERQCNNGKK--
-----------------ISSNDTPYSRTREKLELKRERKAARTLAIITGAFLICWLPFFI
IALIGPF---VDPE-GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKIL-----
FGKYRRGHR---------------------------------------------------
------------------------------------------------------------
---------------
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
M------------------EGAE-GQEELDWEALYLRLPL--------------------
------------------------QNCSWNSTGWEPNW--------NVTVVPNTTWWQAS
-----APFDTPAALVRAAAKAVVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLA
VADLLVACLV-MPLGAVYEVV-QRWT--LGPELCDMWTSGDVLCCTASILHLVAIALDRY
WAVTN-IDYIHASTAKRVGMMIACVWTVSFFV-CIAQLLG-WKDPDWNQRVSEDLRCVVS
QDV----------GYQIFATASSFYVPVLIILILYWRIYQTARKRIRRRRGATARGGVGP
-------PP-----------------------------------------------VPAG
GALVAGGGSGGIAAAVVAVIGRPLPTISETTTTGFTNVSSNNTSPE---KQSCANGLEAD
PPTTGYGAVAAAYYPSLVRRK------PKEAADSKRERKAAKTLAIITGAFVACWLPFFV
LAILVPT---CDCE--VSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRLL-----
CGRRVRRRRA-----------------------------PQ-------------------
------------------------------------------------------------
---------------
