>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
-----------------------------MNGTE--GDNFYVPFSNKTG--LARSPYE-Y
PQY-----------------------------------YLAEPW----------------
------------KYSALAAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMAN
LFMVLFG-FTVTMYTSMN-GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVI
CKPMGNF-RFGNTHAIMGVAFTWIMALAC-AAPPLV-GW-----SRYIPEGMQCSCGPDY
YTLNPNFNNESYVVYMFVVHFLVPFVIIFFCYGRLLCTVKEAAAA---------------
------------------------------------------------------------
--------------------------------------QQ---------ESA--------
----------------------------STQK------AEKEVTRMVVLMVIGFLVCWVP
YASVAFYIFTHQGSDFGATFMTLPAF-------FAKSSALYNPVIYILMNKQFRNCMITT
L-----CC---GKNPLGDDE-SGA-STSKTEVSSVS-TS------PVSPA----------
------------------------------------------------------------
---------------------
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
-----------------------------MNGTE--GPNFYVPFSNITG--VVRSPFE-Q
PQY-----------------------------------YLAEPW----------------
------------QFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVAD
LFMVFGG-FTTTLYTSLH-GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVV
CKPMSNF-RFGENHAIMGVAFTWVMALAC-AAPPLV-GW-----SRYIPEGMQCSCGIDY
YTLKPEVNNESFVIYMFVVHFTIPMIVIFFCYGQLVFTVKEAAAQ---------------
------------------------------------------------------------
--------------------------------------QQ---------ESA--------
----------------------------TTQK------AEKEVTRMVIIMVIFFLICWLP
YASVAMYIFTHQGSNFGPIFMTLPAF-------FAKTASIYNPIIYIMMNKQFRNCMLTS
L-----CC---GKNPLGDDE-ASA-TASKTETSQVA-PA---------------------
------------------------------------------------------------
---------------------
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
-----------------------------MNGTE--GINFYVPMSNKTG--VVRSPFE-Y
PQY-----------------------------------YLAEPW----------------
------------KYRLVCCYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVAD
LFMACFG-FTVTFYTAWN-GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVV
CKPMGNF-RFSATHAMMGIAFTWVMAFSC-AAPPLF-GW-----SRYMPEGMQCSCGPDY
YTHNPDYHNESYVLYMFVIHFIIPVVVIFFSYGRLICKVREAAAQ---------------
------------------------------------------------------------
--------------------------------------QQ---------ESA--------
----------------------------TTQK------AEKEVTRMVILMVLGFMLAWTP
YAVVAFWIFTNKGADFTATLMAVPAF-------FSKSSSLYNPIIYVLMNKQFRNCMITT
I-----CC---GKNPFGDEDVSSTVSQSKTEVSSVS-SS------QVSPA----------
------------------------------------------------------------
---------------------
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
-----------------------------MNGTE--GKNFYVPMSNRTG--LVRSPFE-Y
PQY-----------------------------------YLAEPW----------------
------------QFKILALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAG
TIMVCFG-FTVTFYTAIN-GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVV
CKPMGSF-KFSSSHAFAGIAFTWVMALAC-AAPPLF-GW-----SRYIPEGMQCSCGPDY
YTLNPDYNNESYVIYMFVCHFILPVAVIFFTYGRLVCTVKAAAAQ---------------
------------------------------------------------------------
--------------------------------------QQ---------DSA--------
----------------------------STQK------AEREVTKMVILMVFGFLIAWTP
YATVAAWIFFNKGADFSAKFMAIPAF-------FSKSSALYNPVIYVLLNKQFRNCMLTT
I-----FC---GKNPLGDDE-SSTVSTSKTEVSSVS-PA---------------------
------------------------------------------------------------
---------------------
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
-----------------------------MNGTE--GNNFYVPLSNRTG--LVRSPFE-Y
PQY-----------------------------------YLAEPW----------------
------------QFKLLAVYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAG
AIMVCFG-FTVTFYTAIN-GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVV
CKPMGSF-KFSSTHASAGIAFTWVMAMAC-AAPPLV-GW-----SRYIPEGIQCSCGPDY
YTLNPEYNNESYVLYMFICHFILPVTIIFFTYGRLVCTVKAAAAQ---------------
------------------------------------------------------------
--------------------------------------QQ---------DSA--------
----------------------------STQK------AEREVTKMVILMVLGFLVAWTP
YATVAAWIFFNKGAAFSAQFMAIPAF-------FSKTSALYNPVIYVLLNKQFRSCMLTT
L-----FC---GKNPLGDEE-SSTVSTSKTEVSSVS-PA---------------------
------------------------------------------------------------
---------------------
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
-----------------------------MKQVPEFHEDFYIPIPLDINNLSAYSPFL-V
PQD-----------------------------------HLGNQG----------------
------------IFMAMSVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIAN
LFVAIFG-SPLSFYSFFN-RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVI
CKPLGNF-TFKTPHAIAGCILPWISALAA-SLPPLF-GW-----SRYIPEGLQCSCGPDW
YTTNNKYNNESYVMFLFCFCFAVPFGTIVFCYGQLLITLKLAAKA---------------
------------------------------------------------------------
--------------------------------------QA---------DSA--------
----------------------------STQK------AEREVTKMVVVMVLGFLVCWAP
YASFSLWIVSHRGEEFDLRMATIPSC-------LSKASTVYNPVIYVLMNKQFRSCMMKM
V-----C----GKN-IEEDE-AST-SSQVTQVSSVA-PE------K--------------
------------------------------------------------------------
---------------------
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
-----------------------------MRKMS--EEEFYL-----FKNISSVGPWD-G
PQY-----------------------------------HIAPVW----------------
------------AFYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGG
FLLCIFS-VFPVFVASCN-GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVI
CKPFGNF-RFSSKHALTVVLATWTIGIGV-SIPPFF-GW-----SRFIPEGLQCSCGPDW
YTVGTKYRSESYTWFLFIFCFIVPLSLICFSYTQLLRALKAVAAQ---------------
------------------------------------------------------------
--------------------------------------QQ---------ESA--------
----------------------------TTQK------AEREVSRMVVVMVGSFCVCYVP
YAAFAMYMVNNRNHGLDLRLVTIPSF-------FSKSACIYNPIIYCFMNKQFQACIMKM
V-----C----GKA-MTDES-DTC-SSQKTEVSTVS-ST------QVGPN----------
------------------------------------------------------------
---------------------
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------D
LAETVIA-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVV
CKPFGNV-RFDAKLAIVGIAFSWIWAAVW-TAPPIF-GW-----SRYWPHGLKTSCGPDV
FSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQ---------------
------------------------------------------------------------
--------------------------------------QK---------ESE--------
----------------------------STQK------AEKEVTRMVVVMVLAFC-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
---------MAQQWS-LQRLAGRHPQDSYEDSTQ--SSIFTYTNSN-----STRGPFE-G
PNY-----------------------------------HIAPRW----------------
------------VYHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVAD
LAETVIA-STISVVNQVY-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVV
CKPFGNV-RFDAKLAIVGIAFSWIWAAVW-TAPPIF-GW-----SRYWPHGLKTSCGPDV
FSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQ---------------
------------------------------------------------------------
--------------------------------------QK---------ESE--------
----------------------------STQK------AEKEVTRMVVVMVLAFCFCWGP
YAFFACFAAANPGYPFHPLMAALPAF-------FAKSATIYNPVIYVFMNRQFRNCILQL
F----------GKK-VDDGS-ELS-SASKTEVSSV---S------SVSPA----------
------------------------------------------------------------
---------------------
>    10== Z68193   1 human Red Opsin <>[]
---------MAQQWS-LQRLAGRHPQDSYEDSTQ--SSIFTYTNSN-----STRGPFE-G
PNY-----------------------------------HIAPRW----------------
------------VYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVAD
LAETVIA-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVV
CKPFGNV-RFDAKLAIVGIAFSWIWSAVW-TAPPIF-GW-----SRYWPHGLKTSCGPDV
FSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAIRAVAKQ---------------
------------------------------------------------------------
--------------------------------------QK---------ESE--------
----------------------------STQK------AEKEVTRMVVVMIFAYCVCWGP
YTFFACFAAANPGYAFHPLMAALPAY-------FAKSATIYNPVIYVFMNRQFRNCILQL
F----------GKK-VDDGS-ELS-SASKTEVSSV---S------SVSPA----------
------------------------------------------------------------
---------------------
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
---------MTEAWNVAVFAARRSRDD--DDTTR--GSVFTYTNTN-----NTRGPFE-G
PNY-----------------------------------HIAPRW----------------
------------VYNLVSFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVD
LVETLVA-STISVFNQIF-GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVV
CKPFGNI-KFDSKLAIIGIVFSWVWAWGW-SAPPIF-GW-----SRYWPHGLKTSCGPDV
FSGSVELGCQSFMLTLMITCCFLPLFIIIVCYLQVWMAIRAVAAQ---------------
------------------------------------------------------------
--------------------------------------QK---------ESE--------
----------------------------STQK------AEREVSRMVVVMIVAFCICWGP
YASFVSFAAANPGYAFHPLAAALPAY-------FAKSATIYNPVIYVFMNRQFRNCIMQL
F----------GKK-VDDGS-EAS-TTSRTEVSSVS-NS------SVAPA----------
------------------------------------------------------------
---------------------
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
---------MA-AWE-AAFAARRRHEE--EDTTR--DSVFTYTNSN-----NTRGPFE-G
PNY-----------------------------------HIAPRW----------------
------------VYNLTSVWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVAD
LGETVIA-STISVINQIS-GYFI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVV
CKPFGNI-KFDGKLAVAGILFSWLWSCAW-TAPPIF-GW-----SRYWPHGLKTSCGPDV
FSGSSDPGVQSYMVVLMVTCCFFPLAIIILCYLQVWLAIRAVAAQ---------------
------------------------------------------------------------
--------------------------------------QK---------ESE--------
----------------------------STQK------AEKEVSRMVVVMIVAYCFCWGP
YTFFACFAAANPGYAFHPLAAALPAY-------FAKSATIYNPIIYVFMNRQFRNCILQL
F----------GKK-VDDGS-EVS-T-SRTEVSSVS-NS------SVSPA----------
------------------------------------------------------------
---------------------
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
---------------------------------M--SSNSSQAPPN-----GTPGPFD-G
PQW----------------------------------PYQAPQS----------------
------------TYVGVAVLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVAD
LLVTLCG-SSVSLSNNIN-GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVV
CKPLGDF-QFQRRHAVSGCAFTWGWALLW-SAPPLL-GW-----SSYVPEGLRTSCGPNW
YTGGSN--NNSYILSLFVTCFVLPLSLILFSYTNLLLTLRAAAAQ---------------
------------------------------------------------------------
--------------------------------------QK---------EAD--------
----------------------------TTQR------AEREVTRMVIVMVMAFLLCWLP
YSTFALVVATHKGIIIQPVLASLPSY-------FSKTATVYNPIIYVFMNKQFQSCLLEM
L-----CCGYQPQR-TGKAS-PGT-PGPHADVTAAGLRN------KVMPAHPV-------
------------------------------------------------------------
---------------------
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
----------MESGNVSS----------SLFGNV--STALR---------PEARLSA---
-E---TRLLGWNVPP-------------------EELRHIPEHWLTYPEPPE--------
-----------SMNYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCD
FMMMVK--TPIFIYNSFH-QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVI
TRPMEG--KMTHGKAIAMIIFIYMYATPW-VVACYTETW-----GRFVPEGYLTSCTFDY
LTDN--FDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKA---------------
------------------------------------------------------------
--------------------------------------LR---------DQAKKMN----
--------------VESL----RSNVDKNKET------AEIRIAKAAITICFLFFCSWTP
YGVMSLIGAFGDKTLLTPGATMIPAC-------ACKMVACIDPFVYAISHPRYRMELQKR
CPWL--AL--------NEKA-PES-SAVASTSTTQE-PQ------QTTAA----------
------------------------------------------------------------
---------------------
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
----------MEYHNVS-----------SVLGNV--SSVLR---------PDARLSA---
-E---SRLLGWNVPP-------------------DELRHIPEHWLIYPEPPE--------
-----------SMNYLLGTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCD
FMMMIK--TPIFIYNSFH-QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVI
TRPMEG--KMTHGKAIAMIIFIYLYATPW-VVACYTESW-----GRFVPEGYLTSCTFDY
LTDN--FDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKA---------------
------------------------------------------------------------
--------------------------------------LR---------DQAKKMN----
--------------VDSL----RSNVDKSKEA------AEIRIAKAAITICFLFFASWTP
YGVMSLIGAFGDKTLLTPGATMIPAC-------TCKMVACIDPFVYAISHPRYRMELQKR
CPWL--AI--------SEKA-PES-RAAISTSTTQE-QQ------QTTAA----------
------------------------------------------------------------
---------------------
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
----------ME----------------PLCNAS--EPPLR---------PEAR-SSG-N
GD---LQFLGWNVPP-------------------DQIQYIPEHWLTQLEPPA--------
-----------SMHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFD
LIMCLK--APIF--NSFH-RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVI
TKPMNR--NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDY
LSDN--FDTRLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKA---------------
------------------------------------------------------------
--------------------------------------LR---------EQAKKMN----
--------------VESL----RSNVDKSKET------AEIRIAKAAITICFLFFVSWTP
YGVMSLIGAFGDKSLLTQGATMIPAC-------TCKLVACIDPFVYAISHPRYRLELQKR
CPWL--GV--------NEKS-GEI-SSAQSTTTQEQ-QQ------TTAA-----------
------------------------------------------------------------
---------------------
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
----------MD----------------ALCNAS--EPPLR---------PEARMSSG-S
DE---LQFLGWNVPP-------------------DQIQYIPEHWLTQLEPPA--------
-----------SMHYMLGVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFD
LIMCLK--APIFIYNSFH-RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVI
TKPMNR--NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDY
LSDN--FDTRLFVGTIFLFSFVVPTLMILYYYSQIVGHVFNHEKA---------------
------------------------------------------------------------
--------------------------------------LR---------EQAKKMN----
--------------VESL----RSNVDKSKET------AEIRIAKAAITICFLFFVSWTP
YGVMSLIGAFGDKSLLTPGATMIPAC-------TCKLVACIEPFVYAISHPRYRMELQKR
CPWL--GV--------NEKS-GEA-SSAQSTTTQEQ-TQ------QTSAA----------
------------------------------------------------------------
---------------------
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
-----------------------------MTNAT--GPQMAY-----YG--AASMDFG-Y
PE---GVSIVDFVRP-------------------EIKPYVHQHWYNYPPVNP--------
-----------MWHYLLGVIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSD
LIMLTTN-VPFFTYNCFSGGVWM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNII
CNGFNGP-KLTTGKAVVFALISWVIAIGC-ALPPFF-GW-----GNYILEGILDSCSYDY
LTQD--FNTFSYNIFIFVFDYFLPAAIIVFSYVFIVKAIFAHEAA---------------
------------------------------------------------------------
--------------------------------------MR---------AQAKKMN----
--------------VSTL----RS-NEADAQR------AEIRIAKTALVNVSLWFICWTP
YALISLKGVMGDTSGITPLVSTLPAL-------LAKSCSCYNPFVYAISHPKYRLAITQH
LPWF--CV---HET--ETKS-NDD-SQSNS-TVAQD-KA---------------------
------------------------------------------------------------
---------------------
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
-----------------------------MANVT--GPQMAF-----YG--SGAATFG-Y
PE---GMTVADFVPD-------------------RVKHMVLDHWYNYPPVNP--------
-----------MWHYLLGVVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSD
LIMLTTN-FPPFCYNCFSGGRWM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNII
CNGFNGP-KLTQGKATFMCGLAWVISVGW-SLPPFF-GW-----GSYTLEGILDSCSYDY
FTRD--MNTITYNICIFIFDFFLPASVIVFSYVFIVKAIFAHEAA---------------
------------------------------------------------------------
--------------------------------------MR---------AQAKKMN----
--------------VTNL----RS-NEAETQR------AEIRIAKTALVNVSLWFICWTP
YAAITIQGLLGNAEGITPLLTTLPAL-------LAKSCSCYNPFVYAISHPKFRLAITQH
LPWF--CV---HEK--DPND-VEE-NQSSN-TQTQE-KS---------------------
------------------------------------------------------------
---------------------
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
----------MESFAV-------------AAAQL--GPHFA------------PLS----
-----NGSVVDKVTP-------------------DMAHLISPYWNQFPAMDP--------
-----------IWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISD
FGIMITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVI
VKGMAGR-PMTIPLALGKM---------------------------YVPEGNLTSCGIDY
LERD--WNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKA---------------
------------------------------------------------------------
--------------------------------------MR---------EQAKKMN----
--------------VKSL----RS-SEDAEKS------AEGKLAKVALVTITLWFMAWTP
YLVINCMGLFKF-EGLTPLNTIWGAC-------FAKSAACYNPIVYGISHPKYRLALKEK
CPCC--VF---GKV--DDGK-SSD-AQSQA-TASEA-ES------KA-------------
------------------------------------------------------------
---------------------
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
----------MESFAV-------------AAAQL--GPHFA------------PLS----
-----NGSVVDKVTP-------------------DMAHLISPYWNQFPAMDP--------
-----------IWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISD
FGIMITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVI
VKGMAGR-PMTIPLALGKIAYIWFMSSIW-CLAPAF-GW-----SRYVPEGNLTSCGIDY
LERD--WNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKA---------------
------------------------------------------------------------
--------------------------------------MR---------EQAKKMN----
--------------VKSL----RS-SEDAEKS------AEGKLAKVALVTITLWFMAWTP
YLVINCMGLFKF-EGLTPLNTIWGAC-------FAKSAACYNPIVYGISHPKYRLALKEK
CPCC--VF---GKV--DDGK-SSD-AQSQA-TASEA-ES------KA-------------
------------------------------------------------------------
---------------------
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
----------MDSFAA-------------VATQL--GPQFA------------APS----
-----NGSVVDKVTP-------------------DMAHLISPYWDQFPAMDP--------
-----------IWAKILTAYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISD
FGIMITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVI
VKGMAGR-PMTIPLALGKIAYIWFMSTIWCCLAPVF-GW-----SRYVPEGNLTSCGIDY
LERD--WNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKA---------------
------------------------------------------------------------
--------------------------------------MR---------EQAKKMN----
--------------VKSL----RS-SEDADKS------AEGKLAKVALVTISLWFMAWTP
YLVINCMGLFKF-EGLTPLNTIWGAC-------FAKSAACYNPIVYGISHPKYRLALKEK
CPCC--VF---GKV--DDGK-SSE-AQSQA-TTSEA-ES------KA-------------
------------------------------------------------------------
---------------------
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
----------MERSHLPETP--------FDLAHS--GPRFQ------------AQSSG--
-----NGSVLDNVLP-------------------DMAHLVNPYWSRFAPMDP--------
-----------MMSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSD
FCMMASQ-SPVMIINFYY-ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVI
VKGINGT-PMTIKTSIMKILFIWMMAVFW-TVMPLI-GW-----SAYVPEGNLTACSIDY
MTRM--WNPRSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKA---------------
------------------------------------------------------------
--------------------------------------MR---------EQAKKMN----
--------------VKSL----RS-SEDCDKS------AEGKLAKVALTTISLWFMAWTP
YLVICYFGLFKI-DGLTPLTTIWGAT-------FAKTSAVYNPIVYGISHPKYRIVLKEK
CPMC--VF---GNT--DEPK-PDA-PASDTETTSEA-DS------KA-------------
------------------------------------------------------------
---------------------
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
----------MERSLLPEPP--------LAMALL--GPRFE------------AQTGG--
-----NRSVLDNVLP-------------------DMAPLVNPHWSRFAPMDP--------
-----------TMSKILGLFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSD
FCMMASQ-SPVMIINFYY-ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVI
VKGINGT-PMTIKTSIMKIAFIWMMAVFW-TIMPLI-GW-----SSYVPEGNLTACSIDY
MTRQ--WNPRSYLITYSLFVYYTPLFMICYSYWFIIATVAAHEKA---------------
------------------------------------------------------------
--------------------------------------MR---------DQAKKMN----
--------------VKSL----RS-SEDCDKS------AENKLAKVALTTISLWFMAWTP
YLIICYFGLFKI-DGLTPLTTIWGAT-------FAKTSAVYNPIVYGISHPNDRLVLKEK
CPMC--VC---GTT--DEPK-PDA-PPSDTETTSEA-ES------KD-------------
------------------------------------------------------------
---------------------
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
-----------------------------MIAVS--GPSYE------------AFSYG-G
QARFNNQTVVDKVPP-------------------DMLHLIDANWYQYPPLNP--------
-----------MWHGILGFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISN
FLMMFCM-SPPMVINCYY-ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVI
VKGLSGK-PLSINGALIRIIAIWLFSLGW-TIAPMF-GW-----NRYVPEGNMTACGTDY
FNRG--LLSASYLVCYGIWVYFVPLFLIIYSYWFIIQAVAAHEKN---------------
------------------------------------------------------------
--------------------------------------MR---------EQAKKMN----
--------------VASL----RS-SENQNTS------AECKLAKVALMTISLWFMAWTP
YLVINFSGIFNL-VKISPLFTIWGSL-------FAKANAVYNPIVYGISHPKYRAALFAK
FPSL--AC----AA--EPSS-DAV-STTSG-TTTVT-DN------EKSNA----------
------------------------------------------------------------
---------------------
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
-------------------------------MAN--QLSYS------------SLGWP-Y
QP---NASVVDTMPK-------------------EMLYMIHEHWYAFPPMNP--------
-----------LWYSILGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSD
FCMMAFM-MPTMTSNCFA-ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVI
VRGMAAA-PLTHKKATLLLLFVWIWSGGW-TILPFF-GW-----SRYVPEGNLTSCTVDY
LTKD--WSSASYVVIYGLAVYFLPLITMIYCYFFIVHAVAEHEKQ---------------
------------------------------------------------------------
--------------------------------------LR---------EQAKKMN----
--------------VASL----RANADQQKQS------AECRLAKVAMMTVGLWFMAWTP
YLIISWAGVFSSGTRLTPLATIWGSV-------FAKANSCYNPIVYGISHPRYKAALYQR
FPSL--AC---GSG--ESGS-DVK-SEASA-TTTME-EK------PKIPEA---------
------------------------------------------------------------
---------------------
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
-------------------------------MVE--STTLV------------NQTWW-Y
-----NPTV-----------------------------DIHPHWAKFDPIPD--------
-----------AVYYSVGIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSD
LSFSAINGFPLKTISAFM-KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVI
GRPMAASKKMSHRRAFLMIIFVWMWSIVW-SVGPVF-NW-----GAYVPEGILTSCSFDY
LSTD--PSTRSFILCMYFCGFMLPIIIIAFCYFNIVMSVSNHEKE---------------
------------------------------------------------------------
--------------------------------------MA---------AMAKRLN----
--------------AKEL----RK-AQ-AGAS------AEMKLAKISMVIITQFMLSWSP
YAIIALLAQFGPAEWVTPYAAELPVL-------FAKASAIHNPIVYSVSHPKFREAIQTT
FPWLLTCC---QFD--EKEC-EDA-NDAEE-EVVAS-ER----GGESRDAAQMKEMMAMM
QKMQAQQAAYQP---PPPPQGYPPQGYPPQGAYPPPQGYPPQGYPPQGYPPQGYPPQGAP
PQVEAPQGAPPQGVDNQAYQA
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
--------------------------------MG--RDLRD------------NETWW-Y
-----NPSI-----------------------------VVHPHWREFDQVPD--------
-----------AVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSD
FTFSLVNGFPLMTISCFL-KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVI
GRPMAASKKMSHRRAFIMIIFVWLWSVLW-AIGPIF-GW-----GAYTLEGVLCNCSFDY
ISRD--STTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKE---------------
------------------------------------------------------------
--------------------------------------MA---------AMAKRLN----
--------------AKEL----RK-AQ-AGAN------AEMRLAKISIVIVSQFLLSWSP
YAVVALLAQFGPLEWVTPYAAQLPVM-------FAKASAIHNPMIYSVSHPKFREAISQT
FPWVLTCC---QFD--DKET-EDD-KDAET-EIPAG-ESS--DAAPSADAAQMKEMMAMM
QKMQQQQAAYPPQGYAPPPQGYPPQGYPPQGY--PPQGYPPQGYPP---PPQGAPPQGAP
P------AAPPQGVDNQAYQA
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
---------MMD-----------------VNSSG--RPDLY----------GHLRSFL-L
PEV--GRGLPDLSPDGGADPVAGSWAPHLLS---EVTASPAPTW-DAPPDNASGCGEQIN
--------YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALAD
LSVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGI
TRPLTYPVRQNGKCMAKMILSVWLLSASI-TLPPLF-GW-----AQNVNDDKVCLISQDF
----------GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKF------------
-------------------------------------------PGFPRV----EPDSVIA
LNG---------IVKL----------------------QK---------EVEECAN----
--------------LSRLLKHERKNI--SIFK------REQKAATTLGIIVGAFTVCWLP
FFLLSTARPF----ICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSL
L-----QC--QYRN-INRKL-SAA-GMHEALKLAER-PERPEFVLQNADYCRKK------
------------------------------------------------------------
------------GHDS-----
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
------------------------------------------------------------
-------------------------MPHLLSGFLEVTASPAPTW-DAPPDNVSGCGEQIN
--------YGRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALAD
LSVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGI
TRPLTYPVRQNGKCMAKMILSVWLLSASI-TLPPLF-GW-----AQNVNDDKVCLISQDF
----------GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKF------------
-------------------------------------------PGFPRV----QPESVIS
LNG---------VVKL----------------------QK---------EVEECAN----
--------------LSRLLKHERKNI--SIFK------REQKAATTLGIIVGAFTVCWLP
FFLLSTARPF----ICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRPTSRSL
L-----QC--QYRN-INRKL-SAA-GMHEALKLAER-PERSEFVLQNSDHCGKK------
------------------------------------------------------------
------------GHDT-----
>    31=p A47425 serotonin receptor 5HT-7 - rat
------------------------------------------------------------
-------------------------MPHLLSGFLEVTASPAPTW-DAPPDNVSGCGEQIN
--------YGRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALAD
LSVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGI
TRPLTYPVRQNGKCMAKMILSVWLLSASI-TLPPLF-GW-----AQNVNDDKVCLISQDF
----------GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKF------------
-------------------------------------------PGFPRV----QPESVIS
LNG---------VVKL----------------------QK---------EVEECAN----
--------------LSRLLKHERKNI--SIFK------REQKAATTLGIIVGAFTVCWLP
FFLLSTARPF----ICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSL
L-----QC--QYRN-INRKL-SAA-GMHEALKLAER-PERSEFVLQNSDHCGKK------
------------------------------------------------------------
------------GHDT-----
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
----------MD-----------------VLSP---------------------------
-------------------------------GQGNNTTSPPAPF-ET-GGNTTGISDVT-
--------VSYQ--VITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTD
LMVSVLV-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAI
TDPIDYVNKRTPRRAAALISLTWLIGFLI-SIPPML-GWRTPEDRSDPD---ACTISKDH
----------GYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK---------------
------------------------TVKKVEKTGADTRHGASPAPQPKKS-----------
VNGESGSR---------NWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEH
LPLPSEAG--PTPCAPASFERKNERN--AEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPF-----CESSC-HMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKI
I-----KC--KFCR-Q--------------------------------------------
------------------------------------------------------------
---------------------
>    33=p A35181 serotonin receptor class 1A - rat
----------MD-----------------VFSF---------------------------
-------------------------------GQGNNTTASQEPF-GT-GGNVTSISDVT-
--------FSYQ--VITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTD
LMVSVLV-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAI
TDPIDYVNKRTPRRAAALISLTWLIGFLI-SIPPML-GWRTPEDRSDPD---ACTISKDH
----------GYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK---------------
------------------------TVRKVEKKGAGTSLGTSSAPPPKKS-----------
LNGQPGSG---------DWRRCAENRAVGTPCTNGAVRQGDDEATLEVIEVHRVGNSKEH
LPLPSESG--SNSYAPACLERKNERN--AEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPF-----CESSC-HMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKI
I-----KC--KFCR-R--------------------------------------------
------------------------------------------------------------
---------------------
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
MANFTFGDLALD-----------------VARMG-----------------GLASTPSGL
RST--GLTTPGLSPTGLVTSDFN--DSYGLTGQFINGSHSSRSR-DNASANDTSATNMTD
DRYWSLTVYSHEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVAD
LMVAVLV-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAV
TS-IDYIRRRSARRILLMIMVVWIVALFI-SIPPLF-GWRDP--NNDPDKTGTCIISQDK
----------GYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEET
TLVASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANG
VNSNSSS----------SERLKQIQIETAEAFANGCA----EEASIAMLERQ-CNNGKKI
SSNDTPYS-------------RTREK--LELK------RERKAARTLAIITGAFLICWLP
FFIIALIGPF-----VDPE--GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKI
L-----FG--KYRR-GHR------------------------------------------
------------------------------------------------------------
---------------------
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
MANFTFGDLALD-----------------VARMG-----------------GLASTPSGL
RST--GLTTPGLSPTGLVTSDFN--DSYGLTGQFINGSHSSRSR-DNASANDTSATNMTD
DRYWSLTVYSHEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVAD
LMVAVLV-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAV
TS-IDYIRRRSARRILLMIMVVWIVALFI-SIPPLF-GWRDP--NNDPDKTGTCIISQDK
----------GYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEET
TLVASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANG
VNSNSSS----------SERLKQIQIETAEAFANGCA----EEASIAMLERQ-CNNGKKI
SSNDTPYS-------------RTREK--LELK------RERKAARTLAIITGAFLICWLP
FFIIALIGPF-----VDPE--GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKI
L-----FG--KYRR-GHR------------------------------------------
------------------------------------------------------------
---------------------
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
-MEGAEGQEELD-----------------WEAL-------------------YLRLP--L
QNC--SWNSTGWEPNWNVTVVPN--TTWW---------QASAPF-DTPAALVRAAAK---
-----------------AVVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVAD
LLVACLV-MPLGAVYEVV-QRWT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAV
TN-IDYIHASTAKRVGMMIACVWTVSFFV-CIAQLL-GWKDPDWNQRVSEDLRCVVSQDV
----------GYQIFATASSFYVPVLIILILYWRIYQTARKRIR----------------
-----------------------------RRRGATARGGVGPPP---------VPAGGAL
VAGGGSGGIAAAVVAVIGRPLPTISETTTTGFTNVSS----NNTSP---EKQSCANGLEA
DPPTTGYGAVAAAYYPSLVRRKPKEA--ADSK------RERKAAKTLAIITGAFVACWLP
FFVLAILVPT-----CDCE---VSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRL
L-----CG--RRVR-RRRA------------------PQ---------------------
------------------------------------------------------------
---------------------
