>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
----------MNGTE---------------------------GDNFYVP-----------
-FSNKTGLARSP-YEYPQY-------YLAEPWK---------YSALAAYMFFLILVGFPV
NFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-FTVTMYTSMN-GYFV--FGPTMC
SIEGFFATLGGEVALWSLVVLAIERYIVICKPMGN-FRFGNTHAIMGVAFTWIMALAC-A
APPLVG-W-----SRYIPEGMQCSCGPDYYTLNPNFNNESYVVYMFVVHFLVPFVIIFFC
YGRLLCTVKEAAAA----------------------------------------------
------------------------------------------------------------
--------------------------------QQESA-----------------------
-----------STQKAEKEVTRMVVLMVIGFLVCWVPYASVAFYIFT-HQ--GSDFGATF
MTLPAFFAKSSALYNPVIYILMNKQFRNCMITTLCC--------GKNPLGDDE-------
SGASTSKTEVSSVS-TSPVSPA--------------------------------------
----------------------------------------------------
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
----------MNGTE---------------------------GPNFYVP-----------
-FSNITGVVRSP-FEQPQY-------YLAEPWQ---------FSMLAAYMFLLIVLGFPI
NFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTTLYTSLH-GYFV--FGPTGC
NLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSN-FRFGENHAIMGVAFTWVMALAC-A
APPLVG-W-----SRYIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIVIFFC
YGQLVFTVKEAAAQ----------------------------------------------
------------------------------------------------------------
--------------------------------QQESA-----------------------
-----------TTQKAEKEVTRMVIIMVIFFLICWLPYASVAMYIFT-HQ--GSNFGPIF
MTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSLCC--------GKNPLGDDE-------
ASATASKTE------TSQVAPA--------------------------------------
----------------------------------------------------
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
----------MNGTE---------------------------GINFYVP-----------
-MSNKTGVVRSP-FEYPQY-------YLAEPWK---------YRLVCCYIFFLISTGLPI
NLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-FTVTFYTAWN-GYFV--FGPVGC
AVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGN-FRFSATHAMMGIAFTWVMAFSC-A
APPLFG-W-----SRYMPEGMQCSCGPDYYTHNPDYHNESYVLYMFVIHFIIPVVVIFFS
YGRLICKVREAAAQ----------------------------------------------
------------------------------------------------------------
--------------------------------QQESA-----------------------
-----------TTQKAEKEVTRMVILMVLGFMLAWTPYAVVAFWIFT-NK--GADFTATL
MAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTICC--------GKNPFGDEDV-----S
STVSQSKTEVSSVS-SSQVSPA--------------------------------------
----------------------------------------------------
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
----------MNGTE---------------------------GKNFYVP-----------
-MSNRTGLVRSP-FEYPQY-------YLAEPWQ---------FKILALYLFFLMSMGLPI
NGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-FTVTFYTAIN-GYFV--LGPTGC
AVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSSSHAFAGIAFTWVMALAC-A
APPLFG-W-----SRYIPEGMQCSCGPDYYTLNPDYNNESYVIYMFVCHFILPVAVIFFT
YGRLVCTVKAAAAQ----------------------------------------------
------------------------------------------------------------
--------------------------------QQDSA-----------------------
-----------STQKAEREVTKMVILMVFGFLIAWTPYATVAAWIFF-NK--GADFSAKF
MAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTIFC--------GKNPLGDDE------S
STVSTSKTEVSS------VSPA--------------------------------------
----------------------------------------------------
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
----------MNGTE---------------------------GNNFYVP-----------
-LSNRTGLVRSP-FEYPQY-------YLAEPWQ---------FKLLAVYMFFLICLGLPI
NGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-FTVTFYTAIN-GYFA--LGPTGC
AVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSSTHASAGIAFTWVMAMAC-A
APPLVG-W-----SRYIPEGIQCSCGPDYYTLNPEYNNESYVLYMFICHFILPVTIIFFT
YGRLVCTVKAAAAQ----------------------------------------------
------------------------------------------------------------
--------------------------------QQDSA-----------------------
-----------STQKAEREVTKMVILMVLGFLVAWTPYATVAAWIFF-NK--GAAFSAQF
MAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTLFC--------GKNPLGDEE------S
STVSTSKTEVSS------VSPA--------------------------------------
----------------------------------------------------
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
----------MKQVPEF-------------------------HEDFYIPIPL--------
DINNLS--AYSP-FLVPQD-------HLGNQGI---------FMAMSVFMFFIFIGGASI
NILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-SPLSFYSFFN-RYFI--FGATAC
KIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGN-FTFKTPHAIAGCILPWISALAA-S
LPPLFG-W-----SRYIPEGLQCSCGPDWYTTNNKYNNESYVMFLFCFCFAVPFGTIVFC
YGQLLITLKLAAKA----------------------------------------------
------------------------------------------------------------
--------------------------------QADSA-----------------------
-----------STQKAEREVTKMVVVMVLGFLVCWAPYASFSLWIVS-HR--GEEFDLRM
ATIPSCLSKASTVYNPVIYVLMNKQFRSCMM-KMVC--------GKN-IEEDE-------
ASTSSQVTQVSS------VAPEK-------------------------------------
----------------------------------------------------
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
----------MRKMS---------------------------EEEFYL------------
-FKNIS--SVGP-WDGPQY-------HIAPVWA---------FYLQAAFMGTVFLIGFPL
NAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-VFPVFVASCN-GYFV--FGRHVC
ALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGN-FRFSSKHALTVVLATWTIGIGV-S
IPPFFG-W-----SRFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLICFS
YTQLLRALKAVAAQ----------------------------------------------
------------------------------------------------------------
--------------------------------QQESA-----------------------
-----------TTQKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVN-NR--NHGLDLRL
VTIPSFFSKSACIYNPIIYCFMNKQFQACIM-KMVC--------GKA-MTDES-------
DTCSSQKTEVSTVS-STQVGPN--------------------------------------
----------------------------------------------------
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
----------------------------DLAETVIA-STISIVNQVS-GYFV--LGHPMC
VLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDAKLAIVGIAFSWIWAAVW-T
APPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLC
YLQVWLAIRAVAKQ----------------------------------------------
------------------------------------------------------------
--------------------------------QKESE-----------------------
-----------STQKAEKEVTRMVVVMVLAFC----------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
----------MAQQWSL-------------QRLAGRHPQDSYEDSTQSSI-F--------
TYTNSNS-TRGP-FEGPNY-------HIAPRWV---------YHLTSVWMIFVVIASVFT
NGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISVVNQVY-GYFV--LGHPMC
VLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGN-VRFDAKLAIVGIAFSWIWAAVW-T
APPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLC
YLQVWLAIRAVAKQ----------------------------------------------
------------------------------------------------------------
--------------------------------QKESE-----------------------
-----------STQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAA-NP--GYPFHPLM
AALPAFFAKSATIYNPVIYVFMNRQFRNCIL-QLF---------GKK-VDDGS-------
ELSSASKTEVSSV---SSVSPA--------------------------------------
----------------------------------------------------
>    10== Z68193   1 human Red Opsin <>[]
----------MAQQWSL-------------QRLAGRHPQDSYEDSTQSSI-F--------
TYTNSNS-TRGP-FEGPNY-------HIAPRWV---------YHLTSVWMIFVVTASVFT
NGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISIVNQVS-GYFV--LGHPMC
VLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDAKLAIVGIAFSWIWSAVW-T
APPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLC
YLQVWLAIRAVAKQ----------------------------------------------
------------------------------------------------------------
--------------------------------QKESE-----------------------
-----------STQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAA-NP--GYAFHPLM
AALPAYFAKSATIYNPVIYVFMNRQFRNCIL-QLF---------GKK-VDDGS-------
ELSSASKTEVSSV---SSVSPA--------------------------------------
----------------------------------------------------
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
----------MTEAWNV-------------AVFAARRSRDD-DDTTRGSV-F--------
TYTNTNN-TRGP-FEGPNY-------HIAPRWV---------YNLVSFFMIIVVIASCFT
NGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-STISVFNQIF-GYFI--LGHPLC
VIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGN-IKFDSKLAIIGIVFSWVWAWGW-S
APPIFG-W-----SRYWPHGLKTSCGPDVFSGSVELGCQSFMLTLMITCCFLPLFIIIVC
YLQVWMAIRAVAAQ----------------------------------------------
------------------------------------------------------------
--------------------------------QKESE-----------------------
-----------STQKAEREVSRMVVVMIVAFCICWGPYASFVSFAAA-NP--GYAFHPLA
AALPAYFAKSATIYNPVIYVFMNRQFRNCIM-QLF---------GKK-VDDGS-------
EASTTSRTEVSSVS-NSSVAPA--------------------------------------
----------------------------------------------------
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
----------MA-AWEA-------------AFAARRRHEE--EDTTRDSV-F--------
TYTNSNN-TRGP-FEGPNY-------HIAPRWV---------YNLTSVWMIFVVAASVFT
NGLVLVATWKFKKLRHPLNWILVNLAVADLGETVIA-STISVINQIS-GYFI--LGHPMC
VVEGYTVSACGITALWSLAIISWERWFVVCKPFGN-IKFDGKLAVAGILFSWLWSCAW-T
APPIFG-W-----SRYWPHGLKTSCGPDVFSGSSDPGVQSYMVVLMVTCCFFPLAIIILC
YLQVWLAIRAVAAQ----------------------------------------------
------------------------------------------------------------
--------------------------------QKESE-----------------------
-----------STQKAEKEVSRMVVVMIVAYCFCWGPYTFFACFAAA-NP--GYAFHPLA
AALPAYFAKSATIYNPIIYVFMNRQFRNCIL-QLF---------GKK-VDDGS-------
EVST-SRTEVSSVS-NSSVSPA--------------------------------------
----------------------------------------------------
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
----------MS------------------------------SNSSQAP-----------
----PNG-TPGP-FDGPQW------PYQAPQST---------YVGVAVLMGTVVACASVV
NGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-SSVSLSNNIN-GFFV--FGRRMC
ELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGD-FQFQRRHAVSGCAFTWGWALLW-S
APPLLG-W-----SSYVPEGLRTSCGPNWYTGGS--NNNSYILSLFVTCFVLPLSLILFS
YTNLLLTLRAAAAQ----------------------------------------------
------------------------------------------------------------
--------------------------------QKEAD-----------------------
-----------TTQRAEREVTRMVIVMVMAFLLCWLPYSTFALVVAT-HK--GIIIQPVL
ASLPSYFSKTATVYNPIIYVFMNKQFQSCLL-EMLCCGY----QPQR-TGKAS-------
PGTPGPHADVTAAGLRNKVMPAHPV-----------------------------------
----------------------------------------------------
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
----------MESGNVS-------------SSLFGNVSTAL-RPEARLSA----------
-----ETRLLGW-NVPPEEL-----RHIPEHWLTYPEPPESMNYLLGTLYIFFTLMSMLG
NGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK--TPIFIYNSFH-QGYA--LGHLGC
QIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--KMTHGKAIAMIIFIYMYATPW-V
VACYTETW-----GRFVPEGYLTSCTFDYLTDNF--DTRLFVACIFFFSFVCPTTMITYY
YSQIVGHVFSHEKA----------------------------------------------
------------------------------------------------------------
--------------------------------LRDQAKKMNV------------------
ESL--RSNVDKNKETAEIRIAKAAITICFLFFCSWTPYGVMSLIGAF-GD--KTLLTPGA
TMIPACACKMVACIDPFVYAISHPRYRMELQKRCPWLAL---------NEKAP-------
ESSAVASTSTTQEP--QQTTAA--------------------------------------
----------------------------------------------------
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
----------MEYHNVS-------------SVL-GNVSSVL-RPDARLSA----------
-----ESRLLGW-NVPPDEL-----RHIPEHWLIYPEPPESMNYLLGTLYIFFTVISMIG
NGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMIK--TPIFIYNSFH-QGYA--LGHLGC
QIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--KMTHGKAIAMIIFIYLYATPW-V
VACYTESW-----GRFVPEGYLTSCTFDYLTDNF--DTRLFVACIFFFSFVCPTTMITYY
YSQIVGHVFSHEKA----------------------------------------------
------------------------------------------------------------
--------------------------------LRDQAKKMNV------------------
DSL--RSNVDKSKEAAEIRIAKAAITICFLFFASWTPYGVMSLIGAF-GD--KTLLTPGA
TMIPACTCKMVACIDPFVYAISHPRYRMELQKRCPWLAI---------SEKAP-------
ESRAAISTSTTQEQ--QQTTAA--------------------------------------
----------------------------------------------------
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
----------ME-------------------PLCNASEPPL-RPEAR-SSG---------
---NGDLQFLGW-NVPPDQI-----QYIPEHWLTQLEPPASMHYMLGVFYIFLFCASTVG
NGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIF--NSFH-RGFAIYLGNTWC
QIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNIIIWLYCTPW-V
VLPLTQFW-----DRFVPEGYLTSCSFDYLSDNF--DTRLFVGTIFFFSFVCPTLMILYY
YSQIVGHVFSHEKA----------------------------------------------
------------------------------------------------------------
--------------------------------LREQAKKMNV------------------
ESL--RSNVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAF-GD--KSLLTQGA
TMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWLGV---------NEKSG-------
EISSAQST-TTQEQ--QQTTAA--------------------------------------
----------------------------------------------------
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
----------MD-------------------ALCNASEPPL-RPEARMSSG---------
---SDELQFLGW-NVPPDQI-----QYIPEHWLTQLEPPASMHYMLGVFYIFLFFASTLG
NGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIFIYNSFH-RGFA--LGNTWC
QIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNIIIWLYCTPW-V
VLPLTQFW-----DRFVPEGYLTSCSFDYLSDNF--DTRLFVGTIFLFSFVVPTLMILYY
YSQIVGHVFNHEKA----------------------------------------------
------------------------------------------------------------
--------------------------------LREQAKKMNV------------------
ESL--RSNVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAF-GD--KSLLTPGA
TMIPACTCKLVACIEPFVYAISHPRYRMELQKRCPWLGV---------NEKSG-------
EASSAQST-TTQEQ-TQQTSAA--------------------------------------
----------------------------------------------------
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
--------------------------------MTNATGPQM-AYYGAASMD---------
-FGYPEGVSIVD-FVRPEIK-----PYVHQHWYNYPPVNPMWHYLLGVIYLFLGTVSIFG
NGLVIYLFNKSAALRTPANILVVNLALSDLIMLTTN-VPFFTYNCFSGGVWM--FSPQYC
EIYACLGAITGVCSIWLLCMISFDRYNIICNGFNG-PKLTTGKAVVFALISWVIAIGC-A
LPPFFG-W-----GNYILEGILDSCSYDYLTQDF--NTFSYNIFIFVFDYFLPAAIIVFS
YVFIVKAIFAHEAA----------------------------------------------
------------------------------------------------------------
--------------------------------MRAQAKKMNV------------------
STL--R-SNEADAQRAEIRIAKTALVNVSLWFICWTPYALISLKGVM-GD--TSGITPLV
STLPALLAKSCSCYNPFVYAISHPKYRLAITQHLPWFCV------HE-TETKS-------
NDDSQSNSTVAQDK-A--------------------------------------------
----------------------------------------------------
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
--------------------------------MANVTGPQM-AFYGSGAAT---------
-FGYPEGMTVAD-FVPDRVK-----HMVLDHWYNYPPVNPMWHYLLGVVYLFLGVISIAG
NGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-FPPFCYNCFSGGRWM--FSGTYC
EIYAALGAITGVCSIWTLCMISFDRYNIICNGFNG-PKLTQGKATFMCGLAWVISVGW-S
LPPFFG-W-----GSYTLEGILDSCSYDYFTRDM--NTITYNICIFIFDFFLPASVIVFS
YVFIVKAIFAHEAA----------------------------------------------
------------------------------------------------------------
--------------------------------MRAQAKKMNV------------------
TNL--R-SNEAETQRAEIRIAKTALVNVSLWFICWTPYAAITIQGLL-GN--AEGITPLL
TTLPALLAKSCSCYNPFVYAISHPKFRLAITQHLPWFCV------HE-KDPND-------
VEENQSSNTQTQEK-S--------------------------------------------
----------------------------------------------------
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
----------ME---SF-------------AVAAAQLGPHF-APLS--------------
------NGSVVD-KVTPDMA-----HLISPYWNQFPAMDPIWAKILTAYMIMIGMISWCG
NGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV--LGPMMC
DIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKM------------
---------------YVPEGNLTSCGIDYLERDW--NPRSYLIFYSIFVYYIPLFLICYS
YWFIIAAVSAHEKA----------------------------------------------
------------------------------------------------------------
--------------------------------MREQAKKMNV------------------
KSL--R-SSEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLF-KF---EGLTPLN
TIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------GK-VDDGK-------
SSDAQSQA-TASEA-ESKA-----------------------------------------
----------------------------------------------------
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
----------ME---SF-------------AVAAAQLGPHF-APLS--------------
------NGSVVD-KVTPDMA-----HLISPYWNQFPAMDPIWAKILTAYMIMIGMISWCG
NGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV--LGPMMC
DIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKIAYIWFMSSIW-C
LAPAFG-W-----SRYVPEGNLTSCGIDYLERDW--NPRSYLIFYSIFVYYIPLFLICYS
YWFIIAAVSAHEKA----------------------------------------------
------------------------------------------------------------
--------------------------------MREQAKKMNV------------------
KSL--R-SSEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLF-KF---EGLTPLN
TIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------GK-VDDGK-------
SSDAQSQA-TASEA-ESKA-----------------------------------------
----------------------------------------------------
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
----------MD---SF-------------AAVATQLGPQF-AAPS--------------
------NGSVVD-KVTPDMA-----HLISPYWDQFPAMDPIWAKILTAYMIIIGMISWCG
NGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV--LGPMMC
DIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKIAYIWFMSTIWCC
LAPVFG-W-----SRYVPEGNLTSCGIDYLERDW--NPRSYLIFYSIFVYYIPLFLICYS
YWFIIAAVSAHEKA----------------------------------------------
------------------------------------------------------------
--------------------------------MREQAKKMNV------------------
KSL--R-SSEDADKSAEGKLAKVALVTISLWFMAWTPYLVINCMGLF-KF---EGLTPLN
TIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------GK-VDDGK-------
SSEAQSQA-TTSEA-ESKA-----------------------------------------
----------------------------------------------------
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
-----MERSHLP---ET-------------PFDLAHSGPRF-QAQSSG------------
------NGSVLD-NVLPDMA-----HLVNPYWSRFAPMDPMMSKILGLFTLAIMIISCCG
NGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ETWV--LGPLWC
DIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIKTSIMKILFIWMMAVFW-T
VMPLIG-W-----SAYVPEGNLTACSIDYMTRMW--NPRSYLITYSLFVYYTPLFLICYS
YWFIIAAVAAHEKA----------------------------------------------
------------------------------------------------------------
--------------------------------MREQAKKMNV------------------
KSL--R-SSEDCDKSAEGKLAKVALTTISLWFMAWTPYLVICYFGLF-KI---DGLTPLT
TIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMCVF------GN-TDEPK-------
PDAPASDTETTSEA-DSKA-----------------------------------------
----------------------------------------------------
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
-----MERSLLP---EP-------------PLAMALLGPRF-EAQTGG------------
------NRSVLD-NVLPDMA-----PLVNPHWSRFAPMDPTMSKILGLFTLVILIISCCG
NGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ETWV--LGPLWC
DIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIKTSIMKIAFIWMMAVFW-T
IMPLIG-W-----SSYVPEGNLTACSIDYMTRQW--NPRSYLITYSLFVYYTPLFMICYS
YWFIIATVAAHEKA----------------------------------------------
------------------------------------------------------------
--------------------------------MRDQAKKMNV------------------
KSL--R-SSEDCDKSAENKLAKVALTTISLWFMAWTPYLIICYFGLF-KI---DGLTPLT
TIWGATFAKTSAVYNPIVYGISHPNDRLVLKEKCPMCVC------GT-TDEPK-------
PDAPPSDTETTSEA-ESKD-----------------------------------------
----------------------------------------------------
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
--------------------------------MIAVSGPSY-EAFSYGGQAR--------
-F---NNQTVVD-KVPPDML-----HLIDANWYQYPPLNPMWHGILGFVIGMLGFVSAMG
NGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-SPPMVINCYY-ETWV--LGPLFC
QIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSG-KPLSINGALIRIIAIWLFSLGW-T
IAPMFG-W-----NRYVPEGNMTACGTDYFNRGL--LSASYLVCYGIWVYFVPLFLIIYS
YWFIIQAVAAHEKN----------------------------------------------
------------------------------------------------------------
--------------------------------MREQAKKMNV------------------
ASL--R-SSENQNTSAECKLAKVALMTISLWFMAWTPYLVINFSGIF-NL---VKISPLF
TIWGSLFAKANAVYNPIVYGISHPKYRAALFAKFPSLAC-------A-AEPSS-------
DAVSTTSGTTTVTD-NEKSNA---------------------------------------
----------------------------------------------------
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
----------------------------------MANQLSY-SSLGWPYQP---------
------NASVVD-TMPKEML-----YMIHEHWYAFPPMNPLWYSILGVAMIILGIICVLG
NGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-MPTMTSNCFA-ETWI--LGPFMC
EVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAA-APLTHKKATLLLLFVWIWSGGW-T
ILPFFG-W-----SRYVPEGNLTSCTVDYLTKDW--SSASYVVIYGLAVYFLPLITMIYC
YFFIVHAVAEHEKQ----------------------------------------------
------------------------------------------------------------
--------------------------------LREQAKKMNV------------------
ASL--RANADQQKQSAECRLAKVAMMTVGLWFMAWTPYLIISWAGVF-SS--GTRLTPLA
TIWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPSLAC------GS-GESGS-------
DVKSEASATTTMEE-KPKIPEA--------------------------------------
----------------------------------------------------
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
---------------------------------------MV-ESTTLVNQT---------
-WWY--NPTVD----------------IHPHWAKFDPIPDAVYYSVGIFIGVVGIIGILG
NGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLKTISAFM-KKWI--FGKVAC
QLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSHRRAFLMIIFVWMWSIVW-S
VGPVFN-W-----GAYVPEGILTSCSFDYLSTDP--STRSFILCMYFCGFMLPIIIIAFC
YFNIVMSVSNHEKE----------------------------------------------
------------------------------------------------------------
--------------------------------MAAMAKRLNA------------------
KEL--R--KAQAGASAEMKLAKISMVIITQFMLSWSPYAIIALLAQF-GP--AEWVTPYA
AELPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCCQFDEKE-CEDAN-------
DAEEEVVASER--G-GESRDAAQMKEMMAMMQKMQAQQAAYQP---PPPPQGYPPQGYPP
QGAYPPPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVDNQAYQA
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
----------------------------------------M-GRDLRDNET---------
-WWY--NPSIV----------------VHPHWREFDQVPDAVYYSLGIFIGICGIIGCGG
NGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFL-KKWI--FGFAAC
KVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLW-A
IGPIFG-W-----GAYTLEGVLCNCSFDYISRDS--TTRSNILCMFILGFFGPILIIFFC
YFNIVMSVSNHEKE----------------------------------------------
------------------------------------------------------------
--------------------------------MAAMAKRLNA------------------
KEL--R--KAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQF-GP--LEWVTPYA
AQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKE-TEDDK-------
DAETEIPAGESSDA-APSADAAQMKEMMAMMQKMQQQQAAYPPQGYAPPPQGYPPQGYPP
QGY--PPQGYPPQGYPP---PPQGAPPQGAPP------AAPPQGVDNQAYQA
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
---------MMDVNSSGRPDLYGHLRSFL-LPEVGRGLPDL-SPDGGADPVAGSWAPHLL
S---EVTASPAPTWDAPPDNASGCGEQIN--------YGRVEKVVIGSILTLITLLTIAG
NCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI--FGHFFC
NVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASI-T
LPPLFG-W-----AQNVNDDKVCLISQDF----------GYTIYSTAVAFYIPMSVMLFM
YYQIYKAARKSAAKHKFP--------------GFPRVE----------------------
------------PDSVIALNG-----------------------------------IVKL
Q--------------------------------KEVEECANL------------------
SRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWV
ERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYR----NINRKLSAAGMHEALKL
AERPERPEFVLQNA----------------------------------------------
-------------------------------------DYCRKKGHDS-----
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
-------------------------------------------------------MPHLL
SGFLEVTASPAPTWDAPPDNVSGCGEQIN--------YGRVEKVVIGSILTLITLLTIAG
NCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI--FGHFFC
NVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASI-T
LPPLFG-W-----AQNVNDDKVCLISQDF----------GYTIYSTAVAFYIPMSVMLFM
YYQIYKAARKSAAKHKFP--------------GFPRVQ----------------------
------------PESVISLNG-----------------------------------VVKL
Q--------------------------------KEVEECANL------------------
SRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWV
ERTCLWLGYANSLINPFIYAFFNRDLRPTSRSLLQCQYR----NINRKLSAAGMHEALKL
AERPERSEFVLQNS----------------------------------------------
-------------------------------------DHCGKKGHDT-----
>    31=p A47425 serotonin receptor 5HT-7 - rat
-------------------------------------------------------MPHLL
SGFLEVTASPAPTWDAPPDNVSGCGEQIN--------YGRVEKVVIGSILTLITLLTIAG
NCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI--FGHFFC
NVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASI-T
LPPLFG-W-----AQNVNDDKVCLISQDF----------GYTIYSTAVAFYIPMSVMLFM
YYQIYKAARKSAAKHKFP--------------GFPRVQ----------------------
------------PESVISLNG-----------------------------------VVKL
Q--------------------------------KEVEECANL------------------
SRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWV
ERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYR----NINRKLSAAGMHEALKL
AERPERSEFVLQNS----------------------------------------------
-------------------------------------DHCGKKGHDT-----
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
----------MDVLSP--------------------------------------------
GQGNNTTSPPAP-FET-GGNTTGISDVT---------VSYQ--VITSLLLGTLIFCAVLG
NACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NKWT--LGQVTC
DLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLI-S
IPPMLG-WRTPEDRSDPDA---CTISKDH----------GYTIYSTFGAFYIPLLLMLVL
YGRIFRAARFRIRK---------------------------------------TVKKVEK
TGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEV
HRVGNSKEHLPLPSEAGPTPCAPAS--------FERKNERNA------------------
------EAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF-CESSCH-MPTLL
GAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC----RQ---------------
------------------------------------------------------------
----------------------------------------------------
>    33=p A35181 serotonin receptor class 1A - rat
----------MDVFSF--------------------------------------------
GQGNNTTASQEP-FGT-GGNVTSISDVT---------FSYQ--VITSLLLGTLIFCAVLG
NACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NKWT--LGQVTC
DLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLI-S
IPPMLG-WRTPEDRSDPDA---CTISKDH----------GYTIYSTFGAFYIPLLLMLVL
YGRIFRAARFRIRK---------------------------------------TVRKVEK
KGAGTSLGTSSAPPPKKSLNGQPGSGDWRRCAENRAVGTPCTNGAVRQGDDEATLEVIEV
HRVGNSKEHLPLPSESGSNSYAPAC--------LERKNERNA------------------
------EAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF-CESSCH-MPALL
GAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC----RR---------------
------------------------------------------------------------
----------------------------------------------------
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
MANFTFGDLALDVARMG-----GLASTPSGLRSTGLTTPGL-SPTGLVTSDFND-SYGLT
GQFINGSHSSRS-RDNASANDTSATNMTDDRYWSLTVYSHEHLVLTSVILGLFVLCCIIG
NCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KVWF--LHSEVC
DMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMVVWIVALFI-S
IPPLFG-WRDP--NNDPDKTGTCIISQDK----------GYTIFSTVGAFYLPMLVMMII
YIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNSPDSTTEKKKR
RAPFKSYGCSPRPERKK----------------NRAKKLPENANGVNSNSSS--------
------SERLKQIQIETAEAFANGCAEEASIAMLERQ-CNNGKKISSNDTPYS-------
------RTREKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPF-VD--PEGIPPFA
RSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYR----RGHR-------------
------------------------------------------------------------
----------------------------------------------------
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
MANFTFGDLALDVARMG-----GLASTPSGLRSTGLTTPGL-SPTGLVTSDFND-SYGLT
GQFINGSHSSRS-RDNASANDTSATNMTDDRYWSLTVYSHEHLVLTSVILGLFVLCCIIG
NCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KVWF--LHSEVC
DMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMVVWIVALFI-S
IPPLFG-WRDP--NNDPDKTGTCIISQDK----------GYTIFSTVGAFYLPMLVMMII
YIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNSPDSTTEKKKR
RAPFKSYGCSPRPERKK----------------NRAKKLPENANGVNSNSSS--------
------SERLKQIQIETAEAFANGCAEEASIAMLERQ-CNNGKKISSNDTPYS-------
------RTREKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPF-VD--PEGIPPFA
RSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYR----RGHR-------------
------------------------------------------------------------
----------------------------------------------------
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
-MEGAEGQEELDWEAL-------YLRLP--LQNCSWNSTGW-EPNWNVTVVPNT-TWW--
-------QASAP-FDTPAALVRAAAK--------------------AVVLGLLILATVVG
NVFVIAAILLERHLRSAANNLILSLAVADLLVACLV-MPLGAVYEVV-QRWT--LGPELC
DMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIHASTAKRVGMMIACVWTVSFFV-C
IAQLLG-WKDPDWNQRVSEDLRCVVSQDV----------GYQIFATASSFYVPVLIILIL
YWRIYQTARKRIR---------------------------------------------RR
RGATARGGVGPPP-------------------------VPAGGALVAGGGSGGIAAAV--
--VAVIGRPLPTISETTTTGFTNVSSNNTSP---EKQSCANGLEADPPTTGYGAVAAAYY
PSLVRRKPKEAADSKRERKAAKTLAIITGAFVACWLPFFVLAILVPT-CD--CE-VSPVL
TSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRLLCGRRV----RRRRA------------
---PQ-------------------------------------------------------
----------------------------------------------------
