>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
------------------------MNGTE--GDNFYV-----------------------
---PFS------------NKTG----------------LARSPYEYPQY-------YLAE
PW---------KYSALAAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANL
FMVLFG-FTVTMYTSMN-GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVIC
KPMGNF-RFGNTHAIMGVAFTWIMALAC-AAPPLVG-WS-----RYIPEGMQCSCGPDYY
TLNPNFNNESYVVYMFVVHFLVPFVIIFFCYGRLLCTVKEAAAA----------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------QQ-ESASTQKAEKEVTRMVVLMVIGFLVCWVPY
ASVAFYIFTHQGS---DFGATFMTLPAFFAKSSALYNPVIYILMNKQFRNCMITTLCC--
----------------------GKNPLGDDE-SGA-STSK-TEVSSVS-TSPVSPA----
------------------------------------------------------------
---------
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
------------------------MNGTE--GPNFYV-----------------------
---PFS------------NITG----------------VVRSPFEQPQY-------YLAE
PW---------QFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADL
FMVFGG-FTTTLYTSLH-GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVC
KPMSNF-RFGENHAIMGVAFTWVMALAC-AAPPLVG-WS-----RYIPEGMQCSCGIDYY
TLKPEVNNESFVIYMFVVHFTIPMIVIFFCYGQLVFTVKEAAAQ----------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------QQ-ESATTQKAEKEVTRMVIIMVIFFLICWLPY
ASVAMYIFTHQGS---NFGPIFMTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSLCC--
----------------------GKNPLGDDE-ASA-TASK-TE------TSQVAPA----
------------------------------------------------------------
---------
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
------------------------MNGTE--GINFYV-----------------------
---PMS------------NKTG----------------VVRSPFEYPQY-------YLAE
PW---------KYRLVCCYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADL
FMACFG-FTVTFYTAWN-GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVC
KPMGNF-RFSATHAMMGIAFTWVMAFSC-AAPPLFG-WS-----RYMPEGMQCSCGPDYY
THNPDYHNESYVLYMFVIHFIIPVVVIFFSYGRLICKVREAAAQ----------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------QQ-ESATTQKAEKEVTRMVILMVLGFMLAWTPY
AVVAFWIFTNKGA---DFTATLMAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTICC--
----------------------GKNPFGDEDVSSTVSQSK-TEVSSVS-SSQVSPA----
------------------------------------------------------------
---------
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
------------------------MNGTE--GKNFYV-----------------------
---PMS------------NRTG----------------LVRSPFEYPQY-------YLAE
PW---------QFKILALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGT
IMVCFG-FTVTFYTAIN-GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVC
KPMGSF-KFSSSHAFAGIAFTWVMALAC-AAPPLFG-WS-----RYIPEGMQCSCGPDYY
TLNPDYNNESYVIYMFVCHFILPVAVIFFTYGRLVCTVKAAAAQ----------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------QQ-DSASTQKAEREVTKMVILMVFGFLIAWTPY
ATVAAWIFFNKGA---DFSAKFMAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTIFC--
----------------------GKNPLGDDE-SSTVSTSK-TEVSSVS-PA---------
------------------------------------------------------------
---------
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
------------------------MNGTE--GNNFYV-----------------------
---PLS------------NRTG----------------LVRSPFEYPQY-------YLAE
PW---------QFKLLAVYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGA
IMVCFG-FTVTFYTAIN-GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVC
KPMGSF-KFSSTHASAGIAFTWVMAMAC-AAPPLVG-WS-----RYIPEGIQCSCGPDYY
TLNPEYNNESYVLYMFICHFILPVTIIFFTYGRLVCTVKAAAAQ----------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------QQ-DSASTQKAEREVTKMVILMVLGFLVAWTPY
ATVAAWIFFNKGA---AFSAQFMAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTLFC--
----------------------GKNPLGDEE-SSTVSTSK-TEVSSVS-PA---------
------------------------------------------------------------
---------
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
------------------------MKQVPEFHEDFYI-----------------------
---PIP--------LDINNLSA------------------YSPFLVPQD-------HLGN
QG---------IFMAMSVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANL
FVAIFG-SPLSFYSFFN-RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVIC
KPLGNF-TFKTPHAIAGCILPWISALAA-SLPPLFG-WS-----RYIPEGLQCSCGPDWY
TTNNKYNNESYVMFLFCFCFAVPFGTIVFCYGQLLITLKLAAKA----------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------QA-DSASTQKAEREVTKMVVVMVLGFLVCWAPY
ASFSLWIVSHRGE---EFDLRMATIPSCLSKASTVYNPVIYVLMNKQFRSCMMKMVC---
----------------------GKN-IEEDE-AST-SSQV-TQVSSVA-PEK--------
------------------------------------------------------------
---------
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
------------------------MRKMS--EEEFYL-----------------------
----FK------------NISS------------------VGPWDGPQY-------HIAP
VW---------AFYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGF
LLCIFS-VFPVFVASCN-GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVIC
KPFGNF-RFSSKHALTVVLATWTIGIGV-SIPPFFG-WS-----RFIPEGLQCSCGPDWY
TVGTKYRSESYTWFLFIFCFIVPLSLICFSYTQLLRALKAVAAQ----------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------QQ-ESATTQKAEREVSRMVVVMVGSFCVCYVPY
AAFAMYMVNNRNH---GLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIMKMVC---
----------------------GKA-MTDES-DTC-SSQK-TEVSTVS-STQVGPN----
------------------------------------------------------------
---------
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------DL
AETVIA-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVC
KPFGNV-RFDAKLAIVGIAFSWIWAAVW-TAPPIFG-WS-----RYWPHGLKTSCGPDVF
SGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQ----------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------QK-ESESTQKAEKEVTRMVVVMVLAFC------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
M----AQQWS-LQRLAGRHPQDSYEDSTQ--SSIFTY-----------------------
---TNS------------NST-------------------RGPFEGPNY-------HIAP
RW---------VYHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADL
AETVIA-STISVVNQVY-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVC
KPFGNV-RFDAKLAIVGIAFSWIWAAVW-TAPPIFG-WS-----RYWPHGLKTSCGPDVF
SGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQ----------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------QK-ESESTQKAEKEVTRMVVVMVLAFCFCWGPY
AFFACFAAANPGY---PFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLF----
----------------------GKK-VDDGS-ELS-SASK-TEVSSV---SSVSPA----
------------------------------------------------------------
---------
>    10== Z68193   1 human Red Opsin <>[]
M----AQQWS-LQRLAGRHPQDSYEDSTQ--SSIFTY-----------------------
---TNS------------NST-------------------RGPFEGPNY-------HIAP
RW---------VYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADL
AETVIA-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVC
KPFGNV-RFDAKLAIVGIAFSWIWSAVW-TAPPIFG-WS-----RYWPHGLKTSCGPDVF
SGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAIRAVAKQ----------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------QK-ESESTQKAEKEVTRMVVVMIFAYCVCWGPY
TFFACFAAANPGY---AFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLF----
----------------------GKK-VDDGS-ELS-SASK-TEVSSV---SSVSPA----
------------------------------------------------------------
---------
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
M----TEAWNVAVFAARRSRDD--DDTTR--GSVFTY-----------------------
---TNT------------NNT-------------------RGPFEGPNY-------HIAP
RW---------VYNLVSFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDL
VETLVA-STISVFNQIF-GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVC
KPFGNI-KFDSKLAIIGIVFSWVWAWGW-SAPPIFG-WS-----RYWPHGLKTSCGPDVF
SGSVELGCQSFMLTLMITCCFLPLFIIIVCYLQVWMAIRAVAAQ----------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------QK-ESESTQKAEREVSRMVVVMIVAFCICWGPY
ASFVSFAAANPGY---AFHPLAAALPAYFAKSATIYNPVIYVFMNRQFRNCIMQLF----
----------------------GKK-VDDGS-EAS-TTSR-TEVSSVS-NSSVAPA----
------------------------------------------------------------
---------
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
-----MAAWE-AAFAARRRHEE--EDTTR--DSVFTY-----------------------
---TNS------------NNT-------------------RGPFEGPNY-------HIAP
RW---------VYNLTSVWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADL
GETVIA-STISVINQIS-GYFI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVC
KPFGNI-KFDGKLAVAGILFSWLWSCAW-TAPPIFG-WS-----RYWPHGLKTSCGPDVF
SGSSDPGVQSYMVVLMVTCCFFPLAIIILCYLQVWLAIRAVAAQ----------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------QK-ESESTQKAEKEVSRMVVVMIVAYCFCWGPY
TFFACFAAANPGY---AFHPLAAALPAYFAKSATIYNPIIYVFMNRQFRNCILQLF----
----------------------GKK-VDDGS-EVS--TSR-TEVSSVS-NSSVSPA----
------------------------------------------------------------
---------
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
----------------------------M--SSNSSQ-----------------------
---APP------------NGT-------------------PGPFDGPQWP------YQAP
QS---------TYVGVAVLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADL
LVTLCG-SSVSLSNNIN-GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVC
KPLGDF-QFQRRHAVSGCAFTWGWALLW-SAPPLLG-WS-----SYVPEGLRTSCGPNWY
TGGSN--NNSYILSLFVTCFVLPLSLILFSYTNLLLTLRAAAAQ----------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------QK-EADTTQRAEREVTRMVIVMVMAFLLCWLPY
STFALVVATHKGI---IIQPVLASLPSYFSKTATVYNPIIYVFMNKQFQSCLLEMLCCGY
---------------------QPQR-TGKAS-PGT-PGPH-ADVTAAGLRNKVMPAHP--
------------------------------------------------------------
--------V
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
MESGNVSSS---------------LFGNV--STALR----------PEA-----------
---RLSA---E-------TRLL----------------GWNVPPEELR--------HIPE
HWLTYPEPPESMNYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDF
MMM-VK-TPIFIYNSFH-QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVIT
RPMEG--KMTHGKAIAMIIFIYMYATPW-VVACYTETWG-----RFVPEGYLTSCTFDYL
TDN--FDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKA----------------
------------------------LRDQAKKMNVESL-----------------------
------------------------------------------------------------
---------------------------RSNVDKNKETAEIRIAKAAITICFLFFCSWTPY
GVMSLIGAFGDKT---LLTPGATMIPACACKMVACIDPFVYAISHPRYRMELQKRCPWLA
---------------------LNEK-APESS-AVA-STST-TQEPQ---QTTAA------
------------------------------------------------------------
---------
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
MEYHNVSS----------------VLGNV--SSVLR----------PDA-----------
---RLSA---E-------SRLL----------------GWNVPPDELR--------HIPE
HWLIYPEPPESMNYLLGTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDF
MMM-IK-TPIFIYNSFH-QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVIT
RPMEG--KMTHGKAIAMIIFIYLYATPW-VVACYTESWG-----RFVPEGYLTSCTFDYL
TDN--FDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKA----------------
------------------------LRDQAKKMNVDSL-----------------------
------------------------------------------------------------
---------------------------RSNVDKSKEAAEIRIAKAAITICFLFFASWTPY
GVMSLIGAFGDKT---LLTPGATMIPACTCKMVACIDPFVYAISHPRYRMELQKRCPWLA
---------------------ISEK-APESR-AAI-STST-TQEQQ---QTTAA------
------------------------------------------------------------
---------
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
-----MEP----------------LCNAS--EPPLR----------PEA-----------
---R-SSGNGD-------LQFL----------------GWNVPPDQIQ--------YIPE
HWLTQLEPPASMHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDL
IMC-LK-APIF--NSFH-RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVIT
KPMNR--NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFWD-----RFVPEGYLTSCSFDYL
SDN--FDTRLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKA----------------
------------------------LREQAKKMNVESL-----------------------
------------------------------------------------------------
---------------------------RSNVDKSKETAEIRIAKAAITICFLFFVSWTPY
GVMSLIGAFGDKS---LLTQGATMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWLG
---------------------VNEK-SGEIS-SAQ-STTT-QEQQQ---TTAA-------
------------------------------------------------------------
---------
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
-----MDA----------------LCNAS--EPPLR----------PEA-----------
---RMSSGSDE-------LQFL----------------GWNVPPDQIQ--------YIPE
HWLTQLEPPASMHYMLGVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDL
IMC-LK-APIFIYNSFH-RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVIT
KPMNR--NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFWD-----RFVPEGYLTSCSFDYL
SDN--FDTRLFVGTIFLFSFVVPTLMILYYYSQIVGHVFNHEKA----------------
------------------------LREQAKKMNVESL-----------------------
------------------------------------------------------------
---------------------------RSNVDKSKETAEIRIAKAAITICFLFFVSWTPY
GVMSLIGAFGDKS---LLTPGATMIPACTCKLVACIEPFVYAISHPRYRMELQKRCPWLG
---------------------VNEK-SGEAS-SAQ-STTT-QEQTQ---QTSAA------
------------------------------------------------------------
---------
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
------------------------MTNAT--GPQMAYYGAA-------------------
---SMDFGYPE-------GVSI----------------VDFVRPEIKP--------YVHQ
HWYNYPPVNPMWHYLLGVIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDL
IMLTTN-VPFFTYNCFSGGVWM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIIC
NGFNGP-KLTTGKAVVFALISWVIAIGC-ALPPFFG-WG-----NYILEGILDSCSYDYL
TQD--FNTFSYNIFIFVFDYFLPAAIIVFSYVFIVKAIFAHEAA----------------
------------------------MRAQAKKMNVSTL-----------------------
------------------------------------------------------------
---------------------------RS-NEADAQRAEIRIAKTALVNVSLWFICWTPY
ALISLKGVMGDTS---GITPLVSTLPALLAKSCSCYNPFVYAISHPKYRLAITQHLPWFC
---------------------VHET-ETKSN-DDS-QSNS-TVAQD---KA---------
------------------------------------------------------------
---------
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
------------------------MANVT--GPQMAFYGSG-------------------
---AATFGYPE-------GMTV----------------ADFVPDRVKH--------MVLD
HWYNYPPVNPMWHYLLGVVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDL
IMLTTN-FPPFCYNCFSGGRWM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIIC
NGFNGP-KLTQGKATFMCGLAWVISVGW-SLPPFFG-WG-----SYTLEGILDSCSYDYF
TRD--MNTITYNICIFIFDFFLPASVIVFSYVFIVKAIFAHEAA----------------
------------------------MRAQAKKMNVTNL-----------------------
------------------------------------------------------------
---------------------------RS-NEAETQRAEIRIAKTALVNVSLWFICWTPY
AAITIQGLLGNAE---GITPLLTTLPALLAKSCSCYNPFVYAISHPKFRLAITQHLPWFC
---------------------VHEK-DPNDV-EEN-QSSN-TQTQE---KS---------
------------------------------------------------------------
---------
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
-----MESFA-------------VAAAQL--GPHFA------------------------
---PLS------------NGSV----------------VDKVTPDMAH--------LISP
YWNQFPAMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDF
GIMITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIV
KGMAGR-PMTIPLALGKM---------------------------YVPEGNLTSCGIDYL
ERD--WNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKA----------------
------------------------MREQAKKMNVKSL-----------------------
------------------------------------------------------------
---------------------------RS-SEDAEKSAEGKLAKVALVTITLWFMAWTPY
LVINCMGLFKF-E---GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCV
---------------------FGKV-DDGKS-SDA-QSQA-TASEA---ESKA-------
------------------------------------------------------------
---------
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
-----MESFA-------------VAAAQL--GPHFA------------------------
---PLS------------NGSV----------------VDKVTPDMAH--------LISP
YWNQFPAMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDF
GIMITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIV
KGMAGR-PMTIPLALGKIAYIWFMSSIW-CLAPAFG-WS-----RYVPEGNLTSCGIDYL
ERD--WNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKA----------------
------------------------MREQAKKMNVKSL-----------------------
------------------------------------------------------------
---------------------------RS-SEDAEKSAEGKLAKVALVTITLWFMAWTPY
LVINCMGLFKF-E---GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCV
---------------------FGKV-DDGKS-SDA-QSQA-TASEA---ESKA-------
------------------------------------------------------------
---------
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
-----MDSFA-------------AVATQL--GPQFA------------------------
---APS------------NGSV----------------VDKVTPDMAH--------LISP
YWDQFPAMDPIWAKILTAYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDF
GIMITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIV
KGMAGR-PMTIPLALGKIAYIWFMSTIWCCLAPVFG-WS-----RYVPEGNLTSCGIDYL
ERD--WNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKA----------------
------------------------MREQAKKMNVKSL-----------------------
------------------------------------------------------------
---------------------------RS-SEDADKSAEGKLAKVALVTISLWFMAWTPY
LVINCMGLFKF-E---GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCV
---------------------FGKV-DDGKS-SEA-QSQA-TTSEA---ESKA-------
------------------------------------------------------------
---------
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
MERSHLPETP-------------FDLAHS--GPRFQ------------------------
---AQSSG----------NGSV----------------LDNVLPDMAH--------LVNP
YWSRFAPMDPMMSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDF
CMMASQ-SPVMIINFYY-ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIV
KGINGT-PMTIKTSIMKILFIWMMAVFW-TVMPLIG-WS-----AYVPEGNLTACSIDYM
TRM--WNPRSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKA----------------
------------------------MREQAKKMNVKSL-----------------------
------------------------------------------------------------
---------------------------RS-SEDCDKSAEGKLAKVALTTISLWFMAWTPY
LVICYFGLFKI-D---GLTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMCV
---------------------FGNT-DEPKP-DAP-ASDTETTSEA---DSKA-------
------------------------------------------------------------
---------
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
MERSLLPEPP-------------LAMALL--GPRFE------------------------
---AQTGG----------NRSV----------------LDNVLPDMAP--------LVNP
HWSRFAPMDPTMSKILGLFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDF
CMMASQ-SPVMIINFYY-ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIV
KGINGT-PMTIKTSIMKIAFIWMMAVFW-TIMPLIG-WS-----SYVPEGNLTACSIDYM
TRQ--WNPRSYLITYSLFVYYTPLFMICYSYWFIIATVAAHEKA----------------
------------------------MRDQAKKMNVKSL-----------------------
------------------------------------------------------------
---------------------------RS-SEDCDKSAENKLAKVALTTISLWFMAWTPY
LIICYFGLFKI-D---GLTPLTTIWGATFAKTSAVYNPIVYGISHPNDRLVLKEKCPMCV
---------------------CGTT-DEPKP-DAP-PSDTETTSEA---ESKD-------
------------------------------------------------------------
---------
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
------------------------MIAVS--GPSYE------------------------
---AFSYGGQARF----NNQTV----------------VDKVPPDMLH--------LIDA
NWYQYPPLNPMWHGILGFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNF
LMMFCM-SPPMVINCYY-ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIV
KGLSGK-PLSINGALIRIIAIWLFSLGW-TIAPMFG-WN-----RYVPEGNMTACGTDYF
NRG--LLSASYLVCYGIWVYFVPLFLIIYSYWFIIQAVAAHEKN----------------
------------------------MREQAKKMNVASL-----------------------
------------------------------------------------------------
---------------------------RS-SENQNTSAECKLAKVALMTISLWFMAWTPY
LVINFSGIFNL-V---KISPLFTIWGSLFAKANAVYNPIVYGISHPKYRAALFAKFPSLA
---------------------CAA--EPSSD-AVS-TTSG-TTTVT---DNEKSNA----
------------------------------------------------------------
---------
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
------------------------MANQL----SYS------------------------
---SLGWPYQP-------NASV----------------VDTMPKEMLY--------MIHE
HWYAFPPMNPLWYSILGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDF
CMMAFM-MPTMTSNCFA-ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIV
RGMAAA-PLTHKKATLLLLFVWIWSGGW-TILPFFG-WS-----RYVPEGNLTSCTVDYL
TKD--WSSASYVVIYGLAVYFLPLITMIYCYFFIVHAVAEHEKQ----------------
------------------------LREQAKKMNVASL-----------------------
------------------------------------------------------------
---------------------------RANADQQKQSAECRLAKVAMMTVGLWFMAWTPY
LIISWAGVFSSGT---RLTPLATIWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPSLA
---------------------CGSG-ESGSD-VKS-EASA-TTTME---EKPKIPEA---
------------------------------------------------------------
---------
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
M-----------------------VESTTLVNQTWWY-----------------------
------------------NPTV----------------------------------DIHP
HWAKFDPIPDAVYYSVGIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDL
SFSAINGFPLKTISAFM-KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIG
RPMAASKKMSHRRAFLMIIFVWMWSIVW-SVGPVFN-WG-----AYVPEGILTSCSFDYL
STD--PSTRSFILCMYFCGFMLPIIIIAFCYFNIVMSVSNHEKE----------------
------------------------MAAMAKRLNAKEL-----------------------
------------------------------------------------------------
---------------------------RK--AQAGASAEMKLAKISMVIITQFMLSWSPY
AIIALLAQFGPAE---WVTPYAAELPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLL
TCCQFDEKECEDANDAEEEVVASER---GGE-SRD-AAQM-KEMMAMMQKMQAQQAAYQP
---PPPPQGYPPQGYPPQGAYPPPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQ
GVDNQAYQA
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
------------------------MGRDLRDNETWWY-----------------------
------------------NPSI----------------------------------VVHP
HWREFDQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDF
TFSLVNGFPLMTISCFL-KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIG
RPMAASKKMSHRRAFIMIIFVWLWSVLW-AIGPIFG-WG-----AYTLEGVLCNCSFDYI
SRD--STTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKE----------------
------------------------MAAMAKRLNAKEL-----------------------
------------------------------------------------------------
---------------------------RK--AQAGANAEMRLAKISIVIVSQFLLSWSPY
AVVALLAQFGPLE---WVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVL
TCCQFDDKETEDDKDAETEIPAGES-SDAAP-SAD-AAQM-KEMMAMMQKMQQQQAAYPP
QGYAPPPQGYPPQGYPPQGY--PPQGYPPQGYPP---PPQGAPPQGAPP------AAPPQ
GVDNQAYQA
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
M-----------------------MDVNSSGRPDLYGHLRS--FLLPEVGRGLPDLSPDG
GADPVAGSWAPHLLS---EVTASPAPTW------------DAPPDNASGCGEQI------
------NYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADL
SVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGIT
RPLTYPVRQNGKCMAKMILSVWLLSASI-TLPPLFG-WA-----QNVNDDKVCLISQDF-
---------GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFP------------
--GFPRVE---------------------------------------------PDSVI--
-------------------------------ALNGIVKL-----QKEV---EECAN----
--------------LSRLLKH------ER-KNISIFKREQKAATTLGIIVGAFTVCWLPF
FLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQ---
----------------------CQY-RNINR-KLS-AAGM-HEALKLA-ERPERPE----
--------------FVLQNA----------------------------------DYCRKK
GHDS-----
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
------------------------------------------------------------
---------MPHLLSGFLEVTASPAPTW------------DAPPDNVSGCGEQI------
------NYGRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADL
SVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGIT
RPLTYPVRQNGKCMAKMILSVWLLSASI-TLPPLFG-WA-----QNVNDDKVCLISQDF-
---------GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFP------------
--GFPRVQ---------------------------------------------PESVI--
-------------------------------SLNGVVKL-----QKEV---EECAN----
--------------LSRLLKH------ER-KNISIFKREQKAATTLGIIVGAFTVCWLPF
FLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRPTSRSLLQ---
----------------------CQY-RNINR-KLS-AAGM-HEALKLA-ERPERSE----
--------------FVLQNS----------------------------------DHCGKK
GHDT-----
>    31=p A47425 serotonin receptor 5HT-7 - rat
------------------------------------------------------------
---------MPHLLSGFLEVTASPAPTW------------DAPPDNVSGCGEQI------
------NYGRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADL
SVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGIT
RPLTYPVRQNGKCMAKMILSVWLLSASI-TLPPLFG-WA-----QNVNDDKVCLISQDF-
---------GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFP------------
--GFPRVQ---------------------------------------------PESVI--
-------------------------------SLNGVVKL-----QKEV---EECAN----
--------------LSRLLKH------ER-KNISIFKREQKAATTLGIIVGAFTVCWLPF
FLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQ---
----------------------CQY-RNINR-KLS-AAGM-HEALKLA-ERPERSE----
--------------FVLQNS----------------------------------DHCGKK
GHDT-----
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
------------------------MDVLSPGQGN--------------------------
------------------NTTSP-----------------PAPFETGGNT-TGIS-----
------DVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDL
MVSVLV-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAIT
DPIDYVNKRTPRRAAALISLTWLIGFLI-SIPPMLG-WRTP---EDRSDPDACTISKDH-
---------GYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK----------------
-----------------------TVKKVEKTGADTRHGASPAPQ---------PKKS--V
NGESGS----------RNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEH
LPLPSEAG--PTPCAPASFERKNERNAEA-KRKMALARERKTVKTLGIIMGTFILCWLPF
FIVALVLPFCESSC--HMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIK---
----------------------CKF-CRQ-------------------------------
------------------------------------------------------------
---------
>    33=p A35181 serotonin receptor class 1A - rat
------------------------MDVFSFGQGN--------------------------
------------------NTTAS-----------------QEPFGTGGNV-TSIS-----
------DVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDL
MVSVLV-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAIT
DPIDYVNKRTPRRAAALISLTWLIGFLI-SIPPMLG-WRTP---EDRSDPDACTISKDH-
---------GYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK----------------
-----------------------TVRKVEKKGAGTSLGTSSAPP---------PKKS--L
NGQPGS----------GDWRRCAENRAVGTPCTNGAVRQGDDEATLEVIEVHRVGNSKEH
LPLPSESG--SNSYAPACLERKNERNAEA-KRKMALARERKTVKTLGIIMGTFILCWLPF
FIVALVLPFCESSC--HMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIK---
----------------------CKF-CRR-------------------------------
------------------------------------------------------------
---------
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
------------------------MANFTFGDLALDVARMGGLASTPS---GLRSTGLT-
-----TPGLSPTG-----LVTSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATNMTDD
RYWSLTVYSHEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADL
MVAVLV-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVT
S-IDYIRRRSARRILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK-
---------GYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETT
LVASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGV
NSNSSS----------SERLKQIQIETAEA-FANGCAEE----ASIAMLE-RQCNNGKK-
------------------ISSNDTPYSRT-REKLELKRERKAARTLAIITGAFLICWLPF
FIIALIGPFVDPE---GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILF---
----------------------GKY-RRGHR-----------------------------
------------------------------------------------------------
---------
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
------------------------MANFTFGDLALDVARMGGLASTPS---GLRSTGLT-
-----TPGLSPTG-----LVTSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATNMTDD
RYWSLTVYSHEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADL
MVAVLV-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVT
S-IDYIRRRSARRILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK-
---------GYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETT
LVASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGV
NSNSSS----------SERLKQIQIETAEA-FANGCAEE----ASIAMLE-RQCNNGKK-
------------------ISSNDTPYSRT-REKLELKRERKAARTLAIITGAFLICWLPF
FIIALIGPFVDPE---GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILF---
----------------------GKY-RRGHR-----------------------------
------------------------------------------------------------
---------
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
------------------------MEGAE-GQEELDWEALY--LRLP-----LQNCSWN-
-----STGWEPNW-----NVTVVPNTTWW---------QASAPFDTPAAL----------
----------VRAAAKAVVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADL
LVACLV-MPLGAVYEVV-QRWT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVT
N-IDYIHASTAKRVGMMIACVWTVSFFV-CIAQLLG-WKDPDWNQRVSEDLRCVVSQDV-
---------GYQIFATASSFYVPVLIILILYWRIYQTARKRIRR----------------
-----------------------------RRGATARGGVGPPPV---------PAGGALV
AGGGSGGIAAAVVAVIGRPLPTISETTTTG-FTNVSSNN----TSPEK---QSCANGLEA
DPPTTGYGAVAAAYYPSLVRR------KP-KEAADSKRERKAAKTLAIITGAFVACWLPF
FVLAILVPTCDCE----VSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRLLC---
----------------------GRR-VRRRR----------------------APQ----
------------------------------------------------------------
---------
