>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
----------MN------------------GTE--G--------------------DNFY
VPFS-N--------KTGL-ARSPYE----YPQY----------YLAEPWKYSALAAYMFF
LILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-FTVTMYTSMN-GYFV
--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGNF-RFGNTHAIMGVAFTW
IMALAC-AAPPLVG-WSRYIPEGMQCSCGPDYYTLNPNFNNESYVVYMFVVHFLVPFVII
FFCYGRLLCTV----KEAAAAQQ-------------------------------------
------------------------------------------------------------
----------------------------ESASTQKAEKEVTRMVVLMVIGFLVCWVPYAS
VAFYIFT-HQGS--DFGATFMTLPAFFAKSSALYNPVIYILMNKQFRNCMITTLCC----
GKNPL------GDDE--SGASTSKTEVSSVS--------------------TSPVSPA--
------------------------------------------------------------
---------
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
----------MN------------------GTE--G--------------------PNFY
VPFS-N--------ITGV-VRSPFE----QPQY----------YLAEPWQFSMLAAYMFL
LIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTTLYTSLH-GYFV
--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSNF-RFGENHAIMGVAFTW
VMALAC-AAPPLVG-WSRYIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIVI
FFCYGQLVFTV----KEAAAQQQ-------------------------------------
------------------------------------------------------------
----------------------------ESATTQKAEKEVTRMVIIMVIFFLICWLPYAS
VAMYIFT-HQGS--NFGPIFMTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSLCC----
GKNPL------GDDE--ASATASKTE-------------------------TSQVAPA--
------------------------------------------------------------
---------
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
----------MN------------------GTE--G--------------------INFY
VPMS-N--------KTGV-VRSPFE----YPQY----------YLAEPWKYRLVCCYIFF
LISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-FTVTFYTAWN-GYFV
--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGNF-RFSATHAMMGIAFTW
VMAFSC-AAPPLFG-WSRYMPEGMQCSCGPDYYTHNPDYHNESYVLYMFVIHFIIPVVVI
FFSYGRLICKV----REAAAQQQ-------------------------------------
------------------------------------------------------------
----------------------------ESATTQKAEKEVTRMVILMVLGFMLAWTPYAV
VAFWIFT-NKGA--DFTATLMAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTICC----
GKNPF------GDEDVSSTVSQSKTEVSSVS--------------------SSQVSPA--
------------------------------------------------------------
---------
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
----------MN------------------GTE--G--------------------KNFY
VPMS-N--------RTGL-VRSPFE----YPQY----------YLAEPWQFKILALYLFF
LMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-FTVTFYTAIN-GYFV
--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGSF-KFSSSHAFAGIAFTW
VMALAC-AAPPLFG-WSRYIPEGMQCSCGPDYYTLNPDYNNESYVIYMFVCHFILPVAVI
FFTYGRLVCTV----KAAAAQQQ-------------------------------------
------------------------------------------------------------
----------------------------DSASTQKAEREVTKMVILMVFGFLIAWTPYAT
VAAWIFF-NKGA--DFSAKFMAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTIFC----
GKNPL------GDDE-SSTVSTSKTEVSS-------------------------VSPA--
------------------------------------------------------------
---------
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
----------MN------------------GTE--G--------------------NNFY
VPLS-N--------RTGL-VRSPFE----YPQY----------YLAEPWQFKLLAVYMFF
LICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-FTVTFYTAIN-GYFA
--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGSF-KFSSTHASAGIAFTW
VMAMAC-AAPPLVG-WSRYIPEGIQCSCGPDYYTLNPEYNNESYVLYMFICHFILPVTII
FFTYGRLVCTV----KAAAAQQQ-------------------------------------
------------------------------------------------------------
----------------------------DSASTQKAEREVTKMVILMVLGFLVAWTPYAT
VAAWIFF-NKGA--AFSAQFMAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTLFC----
GKNPL------GDEE-SSTVSTSKTEVSS-------------------------VSPA--
------------------------------------------------------------
---------
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
----------MK------------------QVPEFH--------------------EDFY
IPIPLD--------INNLSAYSPFL----VPQD----------HLGNQGIFMAMSVFMFF
IFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-SPLSFYSFFN-RYFI
--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGNF-TFKTPHAIAGCILPW
ISALAA-SLPPLFG-WSRYIPEGLQCSCGPDWYTTNNKYNNESYVMFLFCFCFAVPFGTI
VFCYGQLLITL----KLAAKAQA-------------------------------------
------------------------------------------------------------
----------------------------DSASTQKAEREVTKMVVVMVLGFLVCWAPYAS
FSLWIVS-HRGE--EFDLRMATIPSCLSKASTVYNPVIYVLMNKQFRSCMM-KMVC----
GKN-I------EEDE--ASTSSQVTQVSS-------------------------VAPEK-
------------------------------------------------------------
---------
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
----------MR------------------KMS--E--------------------EEFY
L-FK-N--------ISSV---GPWD----GPQY----------HIAPVWAFYLQAAFMGT
VFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-VFPVFVASCN-GYFV
--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNF-RFSSKHALTVVLATW
TIGIGV-SIPPFFG-WSRFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLI
CFSYTQLLRAL----KAVAAQQQ-------------------------------------
------------------------------------------------------------
----------------------------ESATTQKAEREVSRMVVVMVGSFCVCYVPYAA
FAMYMVN-NRNH--GLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIM-KMVC----
GKA-M------TDES--DTCSSQKTEVSTVS--------------------STQVGPN--
------------------------------------------------------------
---------
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
------------------------------------DLAETVIA-STISIVNQVS-GYFV
--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNV-RFDAKLAIVGIAFSW
IWAAVW-TAPPIFG-WSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSII
VLCYLQVWLAI----RAVAKQQK-------------------------------------
------------------------------------------------------------
----------------------------ESESTQKAEKEVTRMVVVMVLAFC--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
----------MAQ-QWSLQRLAGRHPQDSYEDS--T--------------------QSSI
FTYT-N--------SNST--RGPFE----GPNY----------HIAPRWVYHLTSVWMIF
VVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISVVNQVY-GYFV
--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNV-RFDAKLAIVGIAFSW
IWAAVW-TAPPIFG-WSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSII
VLCYLQVWLAI----RAVAKQQK-------------------------------------
------------------------------------------------------------
----------------------------ESESTQKAEKEVTRMVVVMVLAFCFCWGPYAF
FACFAAA-NPGY--PFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCIL-QLF-----
GKK-V------DDGS--ELSSASKTEVSSV----------------------SSVSPA--
------------------------------------------------------------
---------
>    10== Z68193   1 human Red Opsin <>[]
----------MAQ-QWSLQRLAGRHPQDSYEDS--T--------------------QSSI
FTYT-N--------SNST--RGPFE----GPNY----------HIAPRWVYHLTSVWMIF
VVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISIVNQVS-GYFV
--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNV-RFDAKLAIVGIAFSW
IWSAVW-TAPPIFG-WSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAII
MLCYLQVWLAI----RAVAKQQK-------------------------------------
------------------------------------------------------------
----------------------------ESESTQKAEKEVTRMVVVMIFAYCVCWGPYTF
FACFAAA-NPGY--AFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCIL-QLF-----
GKK-V------DDGS--ELSSASKTEVSSV----------------------SSVSPA--
------------------------------------------------------------
---------
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
----------MTE-AWNVAVFAARRSRDD-DDT--T--------------------RGSV
FTYT-N--------TNNT--RGPFE----GPNY----------HIAPRWVYNLVSFFMII
VVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-STISVFNQIF-GYFI
--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGNI-KFDSKLAIIGIVFSW
VWAWGW-SAPPIFG-WSRYWPHGLKTSCGPDVFSGSVELGCQSFMLTLMITCCFLPLFII
IVCYLQVWMAI----RAVAAQQK-------------------------------------
------------------------------------------------------------
----------------------------ESESTQKAEREVSRMVVVMIVAFCICWGPYAS
FVSFAAA-NPGY--AFHPLAAALPAYFAKSATIYNPVIYVFMNRQFRNCIM-QLF-----
GKK-V------DDGS--EASTTSRTEVSSVS--------------------NSSVAPA--
------------------------------------------------------------
---------
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
----------MA--AWEAAFAARRRHEE--EDT--T--------------------RDSV
FTYT-N--------SNNT--RGPFE----GPNY----------HIAPRWVYNLTSVWMIF
VVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVIA-STISVINQIS-GYFI
--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGNI-KFDGKLAVAGILFSW
LWSCAW-TAPPIFG-WSRYWPHGLKTSCGPDVFSGSSDPGVQSYMVVLMVTCCFFPLAII
ILCYLQVWLAI----RAVAAQQK-------------------------------------
------------------------------------------------------------
----------------------------ESESTQKAEKEVSRMVVVMIVAYCFCWGPYTF
FACFAAA-NPGY--AFHPLAAALPAYFAKSATIYNPIIYVFMNRQFRNCIL-QLF-----
GKK-V------DDGS--EVST-SRTEVSSVS--------------------NSSVSPA--
------------------------------------------------------------
---------
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
----------MS------------------SNS--S--------------------QAP-
--------------PNGT--PGPFD----GPQWP---------YQAPQSTYVGVAVLMGT
VVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-SSVSLSNNIN-GFFV
--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGDF-QFQRRHAVSGCAFTW
GWALLW-SAPPLLG-WSSYVPEGLRTSCGPNWYTGGSNN--NSYILSLFVTCFVLPLSLI
LFSYTNLLLTL----RAAAAQQK-------------------------------------
------------------------------------------------------------
----------------------------EADTTQRAEREVTRMVIVMVMAFLLCWLPYST
FALVVAT-HKGI--IIQPVLASLPSYFSKTATVYNPIIYVFMNKQFQSCLL-EMLCCGYQ
PQR-T------GKAS--PGTPGPHADVTAAGL-------------------RNKVMPAH-
------------------------------------------PV----------------
---------
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
----------MESGNVSSSLFGNVSTALRPEARLSA--------------------ETRL
LGWNVP--------PEEL-RHIPEH----WLTY----------PEPPESMNYLLGTLYIF
FTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMV-K-TPIFIYNSFH-QGYA
--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEGK--MTHGKAIAMIIFIY
MYATPW-VVACYTETWGRFVPEGYLTSCTFDYLTDNFDT--RLFVACIFFFSFVCPTTMI
TYYYSQIVGHVFSHEKALRDQAKKM-----------------------------------
------------------------------------------------------------
--------------------NVESLRSNVDKNKETAEIRIAKAAITICFLFFCSWTPYGV
MSLIGAF-GDKT--LLTPGATMIPACACKMVACIDPFVYAISHPRYRMELQ-KRCP----
WLA-L------NEKA-PESSAVASTSTTQE---------------------PQQTTAA--
------------------------------------------------------------
---------
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
----------MEYHNVSSVL-GNVSSVLRPDARLSA--------------------ESRL
LGWNVP--------PDEL-RHIPEH----WLIY----------PEPPESMNYLLGTLYIF
FTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMI-K-TPIFIYNSFH-QGYA
--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEGK--MTHGKAIAMIIFIY
LYATPW-VVACYTESWGRFVPEGYLTSCTFDYLTDNFDT--RLFVACIFFFSFVCPTTMI
TYYYSQIVGHVFSHEKALRDQAKKM-----------------------------------
------------------------------------------------------------
--------------------NVDSLRSNVDKSKEAAEIRIAKAAITICFLFFASWTPYGV
MSLIGAF-GDKT--LLTPGATMIPACTCKMVACIDPFVYAISHPRYRMELQ-KRCP----
WLA-I------SEKA-PESRAAISTSTTQE---------------------QQQTTAA--
------------------------------------------------------------
---------
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
----------ME------PLCNASEPPLRPEAR-SSGN-----------------GDLQF
LGWNVP--------PDQI-QYIPEH----WLTQ----------LEPPASMHYMLGVFYIF
LFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCL-K-APIF--NSFH-RGFA
IYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNRN--MTFTKAVIMNIIIW
LYCTPW-VVLPLTQFWDRFVPEGYLTSCSFDYLSDNFDT--RLFVGTIFFFSFVCPTLMI
LYYYSQIVGHVFSHEKALREQAKKM-----------------------------------
------------------------------------------------------------
--------------------NVESLRSNVDKSKETAEIRIAKAAITICFLFFVSWTPYGV
MSLIGAF-GDKS--LLTQGATMIPACTCKLVACIDPFVYAISHPRYRLELQ-KRCP----
WLG-V------NEKS-GEISSAQSTTTQEQ----------------------QQTTAA--
------------------------------------------------------------
---------
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
----------MD------ALCNASEPPLRPEARMSSGS-----------------DELQF
LGWNVP--------PDQI-QYIPEH----WLTQ----------LEPPASMHYMLGVFYIF
LFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCL-K-APIFIYNSFH-RGFA
--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNRN--MTFTKAVIMNIIIW
LYCTPW-VVLPLTQFWDRFVPEGYLTSCSFDYLSDNFDT--RLFVGTIFLFSFVVPTLMI
LYYYSQIVGHVFNHEKALREQAKKM-----------------------------------
------------------------------------------------------------
--------------------NVESLRSNVDKSKETAEIRIAKAAITICFLFFVSWTPYGV
MSLIGAF-GDKS--LLTPGATMIPACTCKLVACIEPFVYAISHPRYRMELQ-KRCP----
WLG-V------NEKS-GEASSAQSTTTQEQ---------------------TQQTSAA--
------------------------------------------------------------
---------
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
----------------MTNATGPQMAYYGAASMDFGYP------------------EGVS
IVDFVR--------PEIK-PYVHQH----WYNY----------PPVNPMWHYLLGVIYLF
LGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTTN-VPFFTYNCFSGGVWM
--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNGP-KLTTGKAVVFALISW
VIAIGC-ALPPFFG-WGNYILEGILDSCSYDYLTQDFNT--FSYNIFIFVFDYFLPAAII
VFSYVFIVKAIFAHEAAMRAQAKKM-----------------------------------
------------------------------------------------------------
--------------------NVSTLRS-NEADAQRAEIRIAKTALVNVSLWFICWTPYAL
ISLKGVM-GDTS--GITPLVSTLPALLAKSCSCYNPFVYAISHPKYRLAIT-QHLP----
WFC-V------HETE-TKSNDDSQSNS-TV---------------------AQDKA----
------------------------------------------------------------
---------
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
----------------MANVTGPQMAFYGSGAATFGYP------------------EGMT
VADFVP--------DRVK-HMVLDH----WYNY----------PPVNPMWHYLLGVVYLF
LGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-FPPFCYNCFSGGRWM
--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNGP-KLTQGKATFMCGLAW
VISVGW-SLPPFFG-WGSYTLEGILDSCSYDYFTRDMNT--ITYNICIFIFDFFLPASVI
VFSYVFIVKAIFAHEAAMRAQAKKM-----------------------------------
------------------------------------------------------------
--------------------NVTNLRS-NEAETQRAEIRIAKTALVNVSLWFICWTPYAA
ITIQGLL-GNAE--GITPLLTTLPALLAKSCSCYNPFVYAISHPKFRLAIT-QHLP----
WFC-V------HEKD-PNDVEENQSSN-TQ---------------------TQEKS----
------------------------------------------------------------
---------
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
-----------------MESFAVAAAQLGPHFAPLS---------------------NGS
VVDKVT--------PDMA-HLISPY----WNQF----------PAMDPIWAKILTAYMIM
IGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV
--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKM----
------------------YVPEGNLTSCGIDYLERDWNP--RSYLIFYSIFVYYIPLFLI
CYSYWFIIAAVSAHEKAMREQAKKM-----------------------------------
------------------------------------------------------------
--------------------NVKSLRS-SEDAEKSAEGKLAKVALVTITLWFMAWTPYLV
INCMGLF-KF-E--GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALK-EKCP----
CCV-F------GKVD-DGKSSDAQSQA-TA---------------------SEAESKA--
------------------------------------------------------------
---------
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
-----------------MESFAVAAAQLGPHFAPLS---------------------NGS
VVDKVT--------PDMA-HLISPY----WNQF----------PAMDPIWAKILTAYMIM
IGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV
--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKIAYIW
FMSSIW-CLAPAFG-WSRYVPEGNLTSCGIDYLERDWNP--RSYLIFYSIFVYYIPLFLI
CYSYWFIIAAVSAHEKAMREQAKKM-----------------------------------
------------------------------------------------------------
--------------------NVKSLRS-SEDAEKSAEGKLAKVALVTITLWFMAWTPYLV
INCMGLF-KF-E--GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALK-EKCP----
CCV-F------GKVD-DGKSSDAQSQA-TA---------------------SEAESKA--
------------------------------------------------------------
---------
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
-----------------MDSFAAVATQLGPQFAAPS---------------------NGS
VVDKVT--------PDMA-HLISPY----WDQF----------PAMDPIWAKILTAYMII
IGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV
--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKIAYIW
FMSTIWCCLAPVFG-WSRYVPEGNLTSCGIDYLERDWNP--RSYLIFYSIFVYYIPLFLI
CYSYWFIIAAVSAHEKAMREQAKKM-----------------------------------
------------------------------------------------------------
--------------------NVKSLRS-SEDADKSAEGKLAKVALVTISLWFMAWTPYLV
INCMGLF-KF-E--GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALK-EKCP----
CCV-F------GKVD-DGKSSEAQSQA-TT---------------------SEAESKA--
------------------------------------------------------------
---------
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
----------ME--RSHLPETPFDLAHSGPRFQAQSS-------------------GNGS
VLDNVL--------PDMA-HLVNPY----WSRF----------APMDPMMSKILGLFTLA
IMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ETWV
--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGINGT-PMTIKTSIMKILFIW
MMAVFW-TVMPLIG-WSAYVPEGNLTACSIDYMTRMWNP--RSYLITYSLFVYYTPLFLI
CYSYWFIIAAVAAHEKAMREQAKKM-----------------------------------
------------------------------------------------------------
--------------------NVKSLRS-SEDCDKSAEGKLAKVALTTISLWFMAWTPYLV
ICYFGLF-KI-D--GLTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLK-EKCP----
MCV-F------GNTD-EPKPDAPASDTETT---------------------SEADSKA--
------------------------------------------------------------
---------
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
----------ME--RSLLPEPPLAMALLGPRFEAQTG-------------------GNRS
VLDNVL--------PDMA-PLVNPH----WSRF----------APMDPTMSKILGLFTLV
ILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ETWV
--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGINGT-PMTIKTSIMKIAFIW
MMAVFW-TIMPLIG-WSSYVPEGNLTACSIDYMTRQWNP--RSYLITYSLFVYYTPLFMI
CYSYWFIIATVAAHEKAMRDQAKKM-----------------------------------
------------------------------------------------------------
--------------------NVKSLRS-SEDCDKSAENKLAKVALTTISLWFMAWTPYLI
ICYFGLF-KI-D--GLTPLTTIWGATFAKTSAVYNPIVYGISHPNDRLVLK-EKCP----
MCV-C------GTTD-EPKPDAPPSDTETT---------------------SEAESKD--
------------------------------------------------------------
---------
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
----------------MIAVSGPSYEAFSYGGQARF--------------------NNQT
VVDKVP--------PDML-HLIDAN----WYQY----------PPLNPMWHGILGFVIGM
LGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-SPPMVINCYY-ETWV
--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSGK-PLSINGALIRIIAIW
LFSLGW-TIAPMFG-WNRYVPEGNMTACGTDYFNRGLLS--ASYLVCYGIWVYFVPLFLI
IYSYWFIIQAVAAHEKNMREQAKKM-----------------------------------
------------------------------------------------------------
--------------------NVASLRS-SENQNTSAECKLAKVALMTISLWFMAWTPYLV
INFSGIF-NL-V--KISPLFTIWGSLFAKANAVYNPIVYGISHPKYRAALF-AKFP----
SLA-C-------AAE-PSSDAVSTTSGTTT---------------------VTDNEKSN-
---------------------------------------------------A--------
---------
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
------------------MANQLSYSSLGWPYQP-----------------------NAS
VVDTMP--------KEML-YMIHEH----WYAF----------PPMNPLWYSILGVAMII
LGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-MPTMTSNCFA-ETWI
--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAAA-PLTHKKATLLLLFVW
IWSGGW-TILPFFG-WSRYVPEGNLTSCTVDYLTKDWSS--ASYVVIYGLAVYFLPLITM
IYCYFFIVHAVAEHEKQLREQAKKM-----------------------------------
------------------------------------------------------------
--------------------NVASLRANADQQKQSAECRLAKVAMMTVGLWFMAWTPYLI
ISWAGVF-SSGT--RLTPLATIWGSVFAKANSCYNPIVYGISHPRYKAALY-QRFP----
SLA-C------GSGE-SGSDVKSEASATTT---------------------MEEKPKIP-
---------------------------------------------------EA-------
---------
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
--------------------------MVESTTLVNQ------------------------
-TWWYN--------PTVD---IHPH----WAKF----------DPIPDAVYYSVGIFIGV
VGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLKTISAFM-KKWI
--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSHRRAFLMIIFVW
MWSIVW-SVGPVFN-WGAYVPEGILTSCSFDYLSTDPST--RSFILCMYFCGFMLPIIII
AFCYFNIVMSVSNHEKEMAAMAKRL-----------------------------------
------------------------------------------------------------
--------------------NAKELRK--AQAGASAEMKLAKISMVIITQFMLSWSPYAI
IALLAQF-GPAE--WVTPYAAELPVLFAKASAIHNPIVYSVSHPKFREAIQ-TTFP----
WLL-TCCQFDEKECE-DANDAEEEVVASER--GGESRDAAQMKEMMAMMQKMQAQQAAYQ
PPPPPQGY--PPQGYPPQGAYPPPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQ
GVDNQAYQA
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
---------------------------MGRDLRDNE------------------------
-TWWYN--------PSIV---VHPH----WREF----------DQVPDAVYYSLGIFIGI
CGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFL-KKWI
--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVW
LWSVLW-AIGPIFG-WGAYTLEGVLCNCSFDYISRDSTT--RSNILCMFILGFFGPILII
FFCYFNIVMSVSNHEKEMAAMAKRL-----------------------------------
------------------------------------------------------------
--------------------NAKELRK--AQAGANAEMRLAKISIVIVSQFLLSWSPYAV
VALLAQF-GPLE--WVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAIS-QTFP----
WVL-TCCQFDDKETE-DDKDAETEIPAGESSDAAPSADAAQMKEMMAMMQKMQQQQAAY-
---PPQGYAPPPQGYPPQGY--PPQGYPPQGYPPQGYPP---PPQGAPPQ-GAPPAAPPQ
GVDNQAYQA
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
M---------MD----VNSSG---RPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSW
APHLLS---------EVT-ASPAPT----WDAPPDNASGCGEQINYGRVEKVVIGSILTL
ITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI
--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVW
LLSASI-TLPPLFG-W--------AQNVNDDKVCLISQD--FGYTIYSTAVAFYIPMSVM
LFMYYQIYKAARKSAAKHKFPG------------FPRVEPDSVIAL--NGIVKLQKEVEE
-----------CANLS--------------------------------------------
--------------------RLLKHER-KNISIFKREQKAATTLGIIVGAFTVCWLPFFL
LSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYR-SLLQ----
CQY-R------NINR--KLSAAGMHEALKLA--------------------ERPERPEF-
------------------------------------------VLQ------NADYCR-KK
GHDS-----
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
------------------------------------------------------------
MPHLLSGF------LEVT-ASPAPT----WDAPPDNVSGCGEQINYGRVEKVVIGSILTL
ITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI
--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVW
LLSASI-TLPPLFG-W--------AQNVNDDKVCLISQD--FGYTIYSTAVAFYIPMSVM
LFMYYQIYKAARKSAAKHKFPG------------FPRVQPESVISL--NGVVKLQKEVEE
-----------CANLS--------------------------------------------
--------------------RLLKHER-KNISIFKREQKAATTLGIIVGAFTVCWLPFFL
LSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRPTSR-SLLQ----
CQY-R------NINR--KLSAAGMHEALKLA--------------------ERPERSEF-
------------------------------------------VLQ------NSDHCG-KK
GHDT-----
>    31=p A47425 serotonin receptor 5HT-7 - rat
------------------------------------------------------------
MPHLLSGF------LEVT-ASPAPT----WDAPPDNVSGCGEQINYGRVEKVVIGSILTL
ITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI
--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVW
LLSASI-TLPPLFG-W--------AQNVNDDKVCLISQD--FGYTIYSTAVAFYIPMSVM
LFMYYQIYKAARKSAAKHKFPG------------FPRVQPESVISL--NGVVKLQKEVEE
-----------CANLS--------------------------------------------
--------------------RLLKHER-KNISIFKREQKAATTLGIIVGAFTVCWLPFFL
LSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYR-SLLQ----
CQY-R------NINR--KLSAAGMHEALKLA--------------------ERPERSEF-
------------------------------------------VLQ------NSDHCG-KK
GHDT-----
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
----------MD----VLSPG------QGNNTTSPPAP---------------------F
ETG-----------GNTT-GISDVT--------------------VSYQ--VITSLLLGT
LIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NKWT
--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTW
LIGFLI-SIPPMLG-WRT--P---EDRSDPDA-CTISKD--HGYTIYSTFGAFYIPLLLM
LVLYGRIFRAARFRIRKTVKKVEKTGADTRHGA-SPAPQPKKSVNGE-SGSRNWRLGVES
KAGGAL-----CANGAVRQGDDGAAL--EVIEVHRVGNSKEHLPL----PSEAGPTPCAP
----ASFERK----------NERNAEA-KRKMALARERKTVKTLGIIMGTFILCWLPFFI
VALVLPF-CESSC-HMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFK-KIIK----
CKF-C------RQ-----------------------------------------------
------------------------------------------------------------
---------
>    33=p A35181 serotonin receptor class 1A - rat
----------MD----VFSFG------QGNNTTASQEP---------------------F
GTG-----------GNVT-SISDVT--------------------FSYQ--VITSLLLGT
LIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NKWT
--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTW
LIGFLI-SIPPMLG-WRT--P---EDRSDPDA-CTISKD--HGYTIYSTFGAFYIPLLLM
LVLYGRIFRAARFRIRKTVRKVEKKGAGTSLGT-SSAPPPKKSLNGQ-PGSGDWRRCAEN
RAVGTP-----CTNGAVRQGDDEATL--EVIEVHRVGNSKEHLPL----PSESGSNSYAP
----ACLERK----------NERNAEA-KRKMALARERKTVKTLGIIMGTFILCWLPFFI
VALVLPF-CESSC-HMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFK-KIIK----
CKF-C------RR-----------------------------------------------
------------------------------------------------------------
---------
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
MANFTFGDLALD----VARMGGLASTPSGLRSTGLTTPGLSPTGLVTSDFNDSYGLTGQF
INGSHSSRSRDNASANDT-SATNMTDDRYWSL-----------TVYSHEHLVLTSVILGL
FVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KVWF
--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMVVW
IVALFI-SIPPLFG-WRD--P---NNDPDKTGTCIISQD--KGYTIFSTVGAFYLPMLVM
MIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNSPDSTTEK
KKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSSSERLKQIQIETAEAFANGCAE
EASIAMLERQCNNGKKISSNDTPYSRT-REKLELKRERKAARTLAIITGAFLICWLPFFI
IALIGPF-VDPE--GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQ-KILF----
GKY-R------RGHR---------------------------------------------
------------------------------------------------------------
---------
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
MANFTFGDLALD----VARMGGLASTPSGLRSTGLTTPGLSPTGLVTSDFNDSYGLTGQF
INGSHSSRSRDNASANDT-SATNMTDDRYWSL-----------TVYSHEHLVLTSVILGL
FVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KVWF
--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMVVW
IVALFI-SIPPLFG-WRD--P---NNDPDKTGTCIISQD--KGYTIFSTVGAFYLPMLVM
MIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNSPDSTTEK
KKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSSSERLKQIQIETAEAFANGCAE
EASIAMLERQCNNGKKISSNDTPYSRT-REKLELKRERKAARTLAIITGAFLICWLPFFI
IALIGPF-VDPE--GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQ-KILF----
GKY-R------RGHR---------------------------------------------
------------------------------------------------------------
---------
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
----------ME----GAEGQ----EELDWEALYLRLP-LQ---------NCSWNSTG-W
EPN-----------WNVT-VVPNTT---WWQASAPF------DTPAALVRAAAKAVVLGL
LILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACLV-MPLGAVYEVV-QRWT
--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIHASTAKRVGMMIACVW
TVSFFV-CIAQLLG-WKD--PD-WNQRVSEDLRCVVSQD--VGYQIFATASSFYVPVLII
LILYWRIYQTARKRIRRRRGATARGGVGP-----PPVPAGGALVAG--GGSGGIAAAVVA
-----------VIGRPLPTISETTTT--GFTNVSSNNTSPEKQSCANGLEADPPTTGYGA
---VAAAYYP----------SLVRRKP-KEAADSKRERKAAKTLAIITGAFVACWLPFFV
LAILVPT-CDCE---VSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQ-RLLC----
GRR-V------RRRR--A-----------------------------------PQ-----
------------------------------------------------------------
---------
